Abstract：
BACKGROUND:Gramineae bee-collected pollen is identified as being at the origin of allergic accidents but the biological potency of Gramineae bee-collected pollen is not well known. Cereal grasses (e.g., Zea) and European wild forage grasses (FG) are contained in bee-collected pollen. METHOD:In this experiment, Zea-mass and FG-mass were identified in bee pollen mass and the proportion of Zea and of FG was calculated using the bee pollen melissopalynology spectrum. Skin reactivity to Zea and to FG were assessed by measuring wheal diameters (W) from skin prick tests using three serial dilutions of bee-collected pollen on 10 allergic patients to Gramineae, in order to calculate the relationship between Zea mass (Masszea) or FG mass (MassFG) in bee pollen and skin reactivity. RESULTS:The linear function Log10(WFG)=0.24(Log10(MassFG))+0.33 (R=0.99) was established using a bee pollen sample with 0.168mg of FG pollen per mg. The linear function Log10(Wzea)=0.23(Log10(Masszea))+0.14 (R=0.99) was established using a bee pollen sample with 0.983mg of Zea pollen per mg. Gramineae allergens seem to be little altered by bee secretions. Gramineae bee pollen retains its allergenic capacity but it depends on the members of the Gramineae family. CONCLUSIONS:To our knowledge this is the first time it has been shown that skin reactivity to Gramineae is proportional to the absolute Gramineae mass contained in the bee-collected pollen and that it depends on the members of the Gramineae family.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Nonotte-Varly Cdoi
10.1016/j.aller.2015.05.003subject
Has Abstractpub_date
2016-05-01 00:00:00pages
232-40issue
3eissn
0301-0546issn
1578-1267pii
S0301-0546(15)00099-3journal_volume
44pub_type
杂志文章abstract：:Platelet-activating factor (PAF), identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine, exhibits potent proinflammatory properties. PAF is produced by numerous cell types, including endothelial cells, neutrophils, monocytes, macrophages, basophils, eosinophils and mastocytes. Since the discovery and identi...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：
更新日期：1997-09-01 00:00:00
abstract：BACKGROUND:Atopic dermatitis (AD) has been associated with impairment of sleep. The aim of this study was to evaluate sleep disorders in AD Latin-American children (4-10 years) from nine countries, and in normal controls (C). METHODS:Parents from 454 C and 340 AD children from referral clinics answered the Children Sl...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.aller.2016.08.014
更新日期：2017-01-01 00:00:00
abstract：:The etiological importance of the dietary factor as related to infantile bronchial asthma is not, at times, sufficiently taken into consideration. Nevertheless, many times foods or their components are capable of provoking asthmatic symptoms. A group of asthmatic children was studied with the goal of more throughly co...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Carrot is frequently involved in food allergies and oral allergy syndromes, usually in association with other foods. Nevertheless, carrot alone is rarely responsible for severe systemic reactions. We report a case of anaphylactic shock due to the inadvertent ingestion of carrot as a hidden allergen contained in an ice...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(02)79128-3
更新日期：2002-07-01 00:00:00
abstract：UNLABELLED:Hypersensitivity reactions to hymenoptera venom are infrequent in paediatric patients. A study was made to determine the incidence of this pathology in children, based on an epidemiological survey targeted to all members of the SEICAP (Sociedad Española de Inmunología Clínica y Alergia Pediátrica/Spanish Soc...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2010.02.004
更新日期：2010-09-01 00:00:00
abstract：:We report a case of nasal candidiasis in an immunocompetent host who denied the use of topical or systemic corticosteroids. The patient was treated with itraconazole 100 mg. with resolution of the symptoms. ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:The results of previous studies on the proliferative response of resting cord blood mononuclear cells (CBMC) of term neonates to human recombinant interleukin 2 (hrIL-2) are contrasting. Some authors have reported a good and others a poor response. In our study we have obtained a significant reactivity, compared with ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:The relationship between ingestion of cow's milk and lymphocyte transformation in cow's milk allergic children was studied. Fifty-six children were selected. Nineteen of them suffered from cow's milk hypersensitivity (HCM); 22 were allergic to several agents except to cow's milk (HOE) and 15 normal and healthy childre...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Autosomal dominant hyper-IgE syndrome (AD-HIES) is a primary immunodeficiency mainly caused by mutations in STAT3, a signalling molecule implicated in the development of appropriate immune responses. We aimed to characterise the innate immune response in AD-HIES. METHODS:The frequency of innate immune cells...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2014.11.002
更新日期：2015-11-01 00:00:00
abstract：:House dust mites (HDM) are a major cause of allergic sensitization and airway disease. Technological advances in assays permit the measurement of major mite allergens in house dust samples more accurately. We compared the results of different methods in the assessment of exposure to domestic mites in sensitized patien...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1996-11-01 00:00:00
abstract：BACKGROUND:Previous studies have shown that serum interleukin 33 serving as an "alarmin" is increased in children with asthma. The objective of this study was to assess the validity of serum IL33 test for early diagnosis of childhood asthma. METHODS:A literature search was performed in June 2016 using PubMed, Embase, ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.aller.2016.12.007
更新日期：2017-01-01 00:00:00
abstract：:The authors selected 28 severe asthmatic children in order to compare the effect of different prophylactic regimens. Patients experiencing at least one wheezing attack per week were included in the study. In a randomized manner, they were allocated Zaditen or Intal. After 8 weeks of active treatment and a 2 week wash-...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1983-01-01 00:00:00
abstract：:For one year dust was sampled monthly from a single mattress. Until August mite counts were at background levels. In September and October there was a burst in the counts for the house-dust mite, Dermatophagoides farinae and for the house mite, Glycyphagus domesticus. Their occurrence might be interpreted as a respons...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1983-05-01 00:00:00
abstract：:Five patients with atopic dermatitis, three males and two females, aged 2 to 17 years, had positive reactions to air allergens (Dermatophagoides pteronyssinus and/or farinae). All the patients suffered from severe recurrent dermatophytosis that responded poorly to antifungal treatment. The results of immunologic evalu...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(02)79135-0
更新日期：2002-09-01 00:00:00
abstract：:Asthma is a complex disease determined by the interaction of different genes and environmental factors. The first genetic investigations in asthma were candidate gene association studies and linkage studies. In recent years research has focused on association studies that scan the entire genome without any prior condi...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2014.07.004
更新日期：2015-11-01 00:00:00
abstract：:The influence of disodium-cromoglycate on different humoral and cellular immune reactions was examined. When injected intravenously DSCG reduces the formation of specific IgG producing (plaque forming) spleen cells in mice. It reduces also the mitogen induced macrophage migration inhibition in vitro. The same reduced ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1982-05-01 00:00:00
abstract：:Asthma morbidity and mortality has increased. One of the possible causes is the excessive use of beta agonists. The aim of this study is to compare the effects of six week treatment with beclomethasone alone (Ibec) or the combination of beclomethasone-salmeterol (Ibe + Isal) on serum potassium (K), CPK-MB and ECG in c...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0301-0546(01)79010-6
更新日期：2001-01-01 00:00:00
abstract：:Immunotherapy delivered a new therapeutic option to the oncologist: Ipilimumab (anti-CTLA-4), Nivolumab and Pembrolizumab (anti-PD1), and Atezolizumab (anti-PD-L1) increase overall survival and show a better safety profile compared to chemotherapy in patients with metastatic melanoma, lung, renal cancer among others. ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2018.04.005
更新日期：2019-01-01 00:00:00
abstract：:Anaphylaxis is a systemic reaction which can be very dangerous in many patients. In addition to the most common antigens (drugs, venoms, foods), physical exercise can provoke anaphylaxis in the sensitized patients. The mechanism of this reaction is still unknown. In this report, we describe a case of exercise-induced ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1986-09-01 00:00:00
abstract：AIM:To prospectively evaluate interferences between viruses of the upper respiratory tract in asymptomatic preschool children. METHODS:Nasal-pharyngeal swabs from 233 preschool aged children were prospectively collected over four consecutive time periods, during one school year. The samples were tested using a RT-PCR ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2018.07.005
更新日期：2019-01-01 00:00:00
abstract：:The study was performed on 22 patients with sensitivity to aspirin which manifested as urticaria and angioedema. Sensitivity to aspirin was established based on the anamnesis of urticaria and angioedema occurring after ingestion of aspirin and oral challenge tests with acetylsalicylic acid. At first, the threshold dos...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1988-09-01 00:00:00
abstract：BACKGROUND:Despite growing evidence suggesting potential association between innate and adaptive immunity in viral-induced acute asthma, there is paucity of data in this area. OBJECTIVE:This study aimed to investigate the association of innate and adaptive immunity with acute asthma attacks by analysing the role of IF...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2016.07.003
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Asthma hospitalization rates in Chilean children have increased in the last 14 years, but little is known about the factors associated with this. OBJECTIVE:Describe clinical characteristics of children hospitalized for asthma exacerbation. METHODS:Observational prospective cohort study in 14 hospitals. Ove...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.aller.2018.02.006
更新日期：2018-01-01 00:00:00
abstract：:In a previous study we had found a high correlation between the positive reaction to standard house dust and to a mites pool extract of 0.86. The study had indicated that the dominant mite found in standard house dust in Barcelona seemed to be D. pteronyssinus. We wished to further confirm this finding by comparing sk...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:A lot of recent works point out the role of the eosinophil as one of the most harmful cells in asthma. Eosinophilic granules contain strongly basiec cytotoxic proteins. Some of these proteins were shown to damage airway epithelial cells and degranulate basophils and mast cells. The concentration of eosinophil-derived ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
abstract：:Toll-like receptors (TLRs) are a family of transmembrane receptors that have been preserved throughout evolution and which selectively recognize a broad spectrum of microbial components and endogenous molecules released by injured tissue. Identification of these ligands by TLRs triggers signalling pathways which lead ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2009.04.004
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:The objective of this study was to evaluate safety and efficacy of Privigen®, a 10% intravenous immunoglobulin (IVIG), in a particular group of paediatric patients (highly sensitive to previous IVIG infusion) affected with Primary Immunodeficiencies (PID). MATERIAL AND METHODS:Patients (n=8) from 3 to 17 ye...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2012.10.006
更新日期：2014-03-01 00:00:00
abstract：:This paper aims to establish the diagnostic reliability of the Prick test and its correlation to other techniques used in allergologic diagnosis: intracutaneous testing, RAST, hemagglutination, histamine liberation test. All of these tests were realized in 55 patients with bronchial asthma and with marked sensitizatio...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:Thirteen patients with severe partially reversible chronic obstructive lung disease received long-term treatment with a sustained-release preparation of theophylline and a beta 2-agonist (terbutaline) alone and in combination. Combination therapy induced significantly greater bronchodilation than treatment with terbut...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-11-01 00:00:00
abstract：BACKGROUND:Epidemiological evidence suggests the existence of a direct link between allergic rhinitis (AR) and asthma. Several studies also support the presence of small-airway dysfunction (SAD) in non-asthmatic children with AR. However, it remains unknown whether SAD can predict the progression of AR to asthma. Our o...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2017.09.025
更新日期：2018-01-01 00:00:00
