The effects of repetitive transcranial magnetic stimulation in an animal model of tinnitus.

abstract：:The aim of this study was to identify the synergistic effect of microRNA expression with classical risk factors of coronary heart disease (CHD) and to explore their diagnostic value for coronary stenotic lesions in subjects with CHD. Plasma samples were obtained from 66 subjects with CHD and from 58 control individual...

journal_title：Scientific reports

authors： Ding XQ,Ge PC,Liu Z,Jia H,Chen X,An FH,Li LH,Chen ZH,Mao HW,Li ZY,Gu Y,Zhu TB,Li CJ,Wang LS,Ma WZ,Yang ZJ,Jia EZ

更新日期：2015-10-08 00:00:00

abstract：:Ionotropic activation of NMDA receptors (NMDARs) requires agonist glutamate and co-agonist glycine. Here we show that glycine enhances the activation of cell survival-promoting kinase Akt in cultured cortical neurons in which both the channel activity of NMDARs and the glycine receptors are pre-inhibited. The effect o...

journal_title：Scientific reports

authors： Hu R,Chen J,Lujan B,Lei R,Zhang M,Wang Z,Liao M,Li Z,Wan Y,Liu F,Feng H,Wan Q

更新日期：2016-10-03 00:00:00

abstract：:Relative gene expression analyses by RT-qPCR (reverse transcription-quantitative PCR) are highly dependent on the reference genes in normalizing the expression data of target genes. Therefore, inappropriate endogenous control genes will lead to inaccurate target gene expression profiles, and the selection and validati...

journal_title：Scientific reports

authors： Liang L,He Z,Yu H,Wang E,Zhang X,Zhang B,Zhang C,Liang Z

更新日期：2020-01-28 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Krukowski K,Feng X,Paladini MS,Chou A,Sacramento K,Grue K,Riparip LK,Jones T,Campbell-Beachler M,Nelson G,Rosi S

更新日期：2018-07-03 00:00:00

abstract：:Primary IgA nephropathy (IgAN) diagnosis is based on IgA-dominant glomerular deposits and histological scoring is done on formalin-fixed paraffin embedded tissue (FFPE) sections using the Oxford classification. Our aim was to use this underexploited resource to extract RNA and identify genes that characterize active (...

journal_title：Scientific reports

authors： Cox SN,Chiurlia S,Divella C,Rossini M,Serino G,Bonomini M,Sirolli V,Aiello FB,Zaza G,Squarzoni I,Gangemi C,Stangou M,Papagianni A,Haas M,Schena FP

更新日期：2020-09-16 00:00:00

abstract：:Congenital ptosis may be associated with abnormalities of visual development and function, including amblyopia, strabismus and refractive errors. However, the prevalence estimates of these abnormalities vary widely. We performed a systematic review and meta-analysis to estimate the prevalence of amblyopia, strabismus ...

journal_title：Scientific reports

authors： Wang Y,Xu Y,Liu X,Lou L,Ye J

更新日期：2018-05-29 00:00:00

abstract：:Near-surface ozone is enhanced under particular chemical reactions and physical processes. This study showed the seasonal variation of near-surface ozone in Nicosia, Cyprus and focused in summers when the highest ozone levels were noted using a seven year hourly dataset from 2007 to 2014. The originality of this study...

journal_title：Scientific reports

authors： Pyrgou A,Hadjinicolaou P,Santamouris M

更新日期：2018-06-15 00:00:00

abstract：:Caloric restriction (CR) is known to promote health and longevity, likely via modification of the gut microbiota (GM). However, functional and metabolic changes induced in the GM during CR are still unidentified. Here, we investigated the short- and long-term effects of CR on the rat GM using a metaproteogenomic appro...

journal_title：Scientific reports

authors： Tanca A,Abbondio M,Palomba A,Fraumene C,Marongiu F,Serra M,Pagnozzi D,Laconi E,Uzzau S

更新日期：2018-10-03 00:00:00

abstract：:Choosing an option increases a person's preference for that option. This phenomenon, called choice-based learning (CBL), has been investigated separately in the contexts of internally guided decision-making (IDM, e.g., preference judgment), for which no objectively correct answer exists, and externally guided decision...

journal_title：Scientific reports

authors： Nakao T,Kanayama N,Katahira K,Odani M,Ito Y,Hirata Y,Nasuno R,Ozaki H,Hiramoto R,Miyatani M,Northoff G

更新日期：2016-08-31 00:00:00

abstract：:Chemotherapy (CTx)-induced premature ovarian failure (POF) in woman remains clinically irreversible. Amniotic fluid stem cells (AFSCs) have shown the potential to treat CTx-induced POF; however, the underlying mechanism is unclear. Here we demonstrate that AFSC-derived exosomes recapitulate the anti-apoptotic effect o...

journal_title：Scientific reports

authors： Xiao GY,Cheng CC,Chiang YS,Cheng WT,Liu IH,Wu SC

更新日期：2016-03-16 00:00:00

abstract：:Extreme weather events (e.g., cyclones, floods, droughts) are capable of changing ecosystems and altering how animals obtain resources. Understanding the behavioural responses of animals being impacted by these natural events can help initiate and ameliorate conservation or management programs. This study investigated...

journal_title：Scientific reports

authors： Matley JK,Eanes S,Nemeth RS,Jobsis PD

更新日期：2019-10-03 00:00:00

abstract：:Copper is an essential trace metal that has been implicated in angiogenesis, the formation of new blood vessels. As tumor growth relies on establishing a functional capillary network for blood supply, copper chelation therapy may hold promise as an anti-cancer strategy by suppressing angiogenesis. To test the anti-ang...

journal_title：Scientific reports

authors： Heuberger DM,Harankhedkar S,Morgan T,Wolint P,Calcagni M,Lai B,Fahrni CJ,Buschmann J

更新日期：2019-10-01 00:00:00

abstract：:Previous studies have shown that CD61 (integrin-β3) promotes the differentiation of human umbilical cord mesenchymal stem cells (hUC-MSCs) into germ-like cells. However, the mechanism remains unclear. In this study, we showed that overexpression of CD61 in canine adipose-derived mesenchymal stem cells (cADMSCs) promot...

journal_title：Scientific reports

authors： Fang J,Wei Y,Lv C,Peng S,Zhao S,Hua J

更新日期：2017-03-03 00:00:00

abstract：:Hyperactivated mTOR signaling in the developing brain has been implicated in multiple forms of pathology including tuberous sclerosis complex (TSC). To date, various phenotypic defects such as cortical lamination irregularity, subependymal nodule formation, dysmorphic astrocyte differentiation and dendritic malformati...

journal_title：Scientific reports

authors： Shin J,Kim M,Jung HJ,Cha HL,Suh-Kim H,Ahn S,Jung J,Kim Y,Jun Y,Lee S,Hwang D,Kim J

更新日期：2017-06-06 00:00:00

abstract：:In addition to its role in sister chromatid cohesion, genome stability and integrity, the cohesin complex is involved in gene transcription. Mutations in core cohesin subunits SMC1A, SMC3 and RAD21, or their regulators NIPBL and HDAC8, cause Cornelia de Lange syndrome (CdLS). Recent evidence reveals that gene expressi...

journal_title：Scientific reports

authors： Mannini L,C Lamaze F,Cucco F,Amato C,Quarantotti V,Rizzo IM,Krantz ID,Bilodeau S,Musio A

更新日期：2015-11-19 00:00:00

abstract：:Obesity involves alterations in transcriptional programs that can change in response to genetic and environmental signals through chromatin modifications. Since chromatin modifications involve different biochemical, neurological and molecular signaling pathways related to energy homeostasis, we hypothesize that geneti...

journal_title：Scientific reports

authors： Giri AK,Parekatt V,Dwivedi OP,Banerjee P,Bandesh K,Prasad G,Tandon N,Bharadwaj D

更新日期：2018-03-02 00:00:00

abstract：:The present work demonstrates the synthesis, characterization and biological activities of different concentrations of tin doped indium oxide nanoparticles (Sn doped In2O3 NPs), i.e., (Sn/In = 5%, 10% and 15%). We have synthesized different size (38.11 nm, 18.46 nm and 10.21 nm) of Sn doped In2O3 NPs. by using an ultr...

journal_title：Scientific reports

authors： Rehman S,Asiri SM,Khan FA,Jermy BR,Ravinayagam V,Alsalem Z,Jindan RA,Qurashi A

更新日期：2020-02-24 00:00:00

abstract：:Skin-derived dendritic cells (DCs) play a crucial role in the maintenance of immune homeostasis due to their role in antigen trafficking from the skin to the draining lymph nodes (dLNs). To quantify the spatiotemporal regulation of skin-derived DCs in vivo, we generated knock-in mice expressing the photoconvertible fl...

journal_title：Scientific reports

authors： Tomura M,Hata A,Matsuoka S,Shand FH,Nakanishi Y,Ikebuchi R,Ueha S,Tsutsui H,Inaba K,Matsushima K,Miyawaki A,Kabashima K,Watanabe T,Kanagawa O

更新日期：2014-08-12 00:00:00

abstract：:This work highlights the possibility of using microstructured fibres with predefined doped regions to produce functional microstructures at a fibre facet with differential chemical etching. A specially designed silica microstructured fibre (MSF) that possesses specific boron-doped silica regions was fabricated for the...

journal_title：Scientific reports

authors： Fu Y,Morency S,Bachus K,Simon D,Hutama T,Gibson GTT,Messaddeq Y,Oleschuk RD

更新日期：2016-02-19 00:00:00

abstract：:Numerous past studies have investigated neurophysiological correlates of music-syntactic processing. However, only little is known about how prior knowledge about an upcoming syntactically irregular event modulates brain correlates of music-syntactic processing. Two versions of a short chord sequence were presented re...

journal_title：Scientific reports

authors： Guo S,Koelsch S

更新日期：2016-01-19 00:00:00

abstract：:Evidence showed preventive impacts of the highly active antiretroviral therapy (HAART) on the Human Immunodeficiency Virus (HIV) transmission amomg heterosexual population, however, that is of deficit among men who have sex with men (MSM). The aim was to systematically examine the efficacy of HAART on HIV transmission...

journal_title：Scientific reports

authors： Jiang Y,Su S,Borné Y

更新日期：2020-01-23 00:00:00

abstract：:Receptivity is a limited time in which uterine endometrium can establish a successful dialogue with blastocyst. This study was to investigate the effect of asynchronous embryo transfer on uterine receptivity in mice. Embryos under different stages were transferred into two oviduct sides of a recipient mouse on day 1 o...

journal_title：Scientific reports

authors： Li SJ,Wang TS,Qin FN,Huang Z,Liang XH,Gao F,Song Z,Yang ZM

更新日期：2015-11-04 00:00:00

abstract：:Cancer dissemination is initiated by the movement of cells into the vasculature which has been reported to be triggered by EMT (epithelial to mesenchymal transition). Cellular dissemination also requires proteases that remodel the extracellular matrix. The protease, plasmin is a prominent player in matrix remodeling a...

journal_title：Scientific reports

authors： Bydoun M,Sterea A,Weaver ICG,Bharadwaj AG,Waisman DM

更新日期：2018-09-20 00:00:00

abstract：:In this study, Tb3+-doped natural sodium feldspar (NaAlSi3O8) phosphors have been successfully prepared using high-temperature solid-state method with natural sodium feldspar as a substrate. Energy-dispersive X-ray spectrometry analysis (EDX) of NaAlSi3O8 showed that 0.03 wt% of Eu element was present, and elemental d...

journal_title：Scientific reports

authors： Halmurat D,Yusufu T,Wang QL,He J,Sidike A

更新日期：2019-10-10 00:00:00

abstract：:Micro/nanophotonic structures that are capable of optical wave-front shaping are implemented in optical waveguides and passive optical devices to alter the phase of the light propagating through them. The beam division directions and beam power distribution depend on the design of the micro/nanostructures. The ultimat...

journal_title：Scientific reports

authors： Li P,Han Y,Wang W,Liu Y,Jin P,Leng J

更新日期：2017-03-09 00:00:00

abstract：:Proteomics studies of fungal systems have progressed dramatically based on the availability of more fungal genome sequences in recent years. Different proteomics strategies have been applied toward characterization of fungal proteome and revealed important gene functions and proteome dynamics. Presented here is the ap...

journal_title：Scientific reports

authors： Sun S,Xie S,Cheng Y,Yu H,Zhao H,Li M,Li X,Zhang X,Yuan JS,Dai SY

更新日期：2017-09-12 00:00:00

abstract：:Gut dysbiosis contributes to the development of a dysfunctional gut barrier, facilitating the translocation of bacteria and inflammagens, and is implicated in colorectal cancer (CRC) pathogenesis. Such 'leaky gut' conditions result in systemic inflammation, of which a hallmark is increased hypercoagulability. Fluoresc...

journal_title：Scientific reports

authors： de Waal GM,de Villiers WJS,Forgan T,Roberts T,Pretorius E

更新日期：2020-05-29 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Zaluski R,Bittarello AC,Vieira JCS,Braga CP,Padilha PM,Fernandes MDS,Bovi TS,Orsi RO

更新日期：2020-04-07 00:00:00

abstract：:Joint deterioration and associated chronic pain are common among people with haemophilia (PWH), having an impact on quality-of-life. Though non-pharmacological strategies are recommended, psychological interventions to promote pain control and quality-of-life have scarcely been tested in haemophilia. This randomised c...

journal_title：Scientific reports

authors： Paredes AC,Costa P,Fernandes S,Lopes M,Carvalho M,Almeida A,Pinto PR

更新日期：2019-09-16 00:00:00

abstract：:GABAA receptor-mediated inhibition depends on the maintenance of low level intracellular [Cl-] concentration, which in adult depends on neuron specific K+-Cl- cotransporter-2 (KCC2). Previous studies have shown that KCC2 was downregulated in both epileptic patients and various epileptic animal models. However, the tem...

journal_title：Scientific reports

authors： Chen L,Wan L,Wu Z,Ren W,Huang Y,Qian B,Wang Y

更新日期：2017-03-13 00:00:00