Differential regulation of receptivity in two uterine horns of a recipient mouse following asynchronous embryo transfer.


:Receptivity is a limited time in which uterine endometrium can establish a successful dialogue with blastocyst. This study was to investigate the effect of asynchronous embryo transfer on uterine receptivity in mice. Embryos under different stages were transferred into two oviduct sides of a recipient mouse on day 1 of pseudopregnancy. Our results showed the asynchronously transferred embryos can implant in all groups. Compared to zygote-transfer group, the length of implanted embryos is longer in 8-cell embryo- or blastocyst-transfer group. The levels of Snail and COX-2 immunostaining in blastocyst-transfer group are significantly stronger than that in zygote-transfer group. Embryos in blastocyst-transfer group migrate faster than that in zygote-transfer group within uterus. Blastocysts are in a state of developmental delay after they are transferred into oviducts, and they are reactivated and implanted rapidly in uterus. The developmental rate to newborn in zygote-transfer group is obviously higher than that in blastocyst-transfer group, suggesting that a delay in embryo development and implantation will lead to a decrease of litter size. These results indicated that the window of implantation is differentially regulated in two uterine horns of a recipient by embryos at different stages.


Sci Rep


Scientific reports


Li SJ,Wang TS,Qin FN,Huang Z,Liang XH,Gao F,Song Z,Yang ZM




Has Abstract


2015-11-04 00:00:00










  • Author Correction: Designing a whole cell bioreporter to show antioxidant activities of agents that work by promotion of the KEAP1-NRF2 signaling pathway.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误


    authors: Mozaheb N,Arefian E,Amoozegar MA

    更新日期:2020-10-28 00:00:00

  • Historical BCG vaccination combined with drug treatment enhances inhibition of mycobacterial growth ex vivo in human peripheral blood cells.

    abstract::Tuberculosis (TB) is a leading infectious cause of death globally. Drug treatment and vaccination, in particular with Bacillus Calmette-Guérin (BCG), remain the main strategies to control TB. With the emergence of drug resistance, it has been proposed that a combination of TB vaccination with pharmacological treatment...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Prabowo SA,Zelmer A,Stockdale L,Ojha U,Smith SG,Seifert K,Fletcher HA

    更新日期:2019-03-19 00:00:00

  • Persisting and Increasing Neutrophil Infiltration Associates with Gastric Carcinogenesis and E-cadherin Downregulation.

    abstract::H. pylori-induced chronic inflammation is considered the most important cause of gastric cancer. The actual process how chronic inflammation triggers gastric carcinogenesis is still not clear. In this study, neutrophils and relative markers in gastric cancer development were examined with immunohistochemistry and fluo...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Fu H,Ma Y,Yang M,Zhang C,Huang H,Xia Y,Lu L,Jin W,Cui D

    更新日期:2016-07-14 00:00:00

  • Author Correction: Rectosigmoidal manifestations of venous malformations: MR imaging findings and interdisciplinary therapeutic modalities.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误


    authors: Brill R,Brill E,Uller W,Teusch V,Gufler H,Hammer S,Fellner C,Evert K,Goldann C,Helm M,Rosendahl J,Wohlgemuth WA

    更新日期:2020-02-07 00:00:00

  • Variation of soil organic carbon and physical properties in relation to land uses in the Yellow River Delta, China.

    abstract::Soil physical properties and soil organic carbon (SOC) are considered as important factors of soil quality. Arable land, grassland, and forest land coexist in the saline-alkali reclamation area of the Yellow River Delta (YRD), China. Such different land uses strongly influence the services of ecosystem to induce soil ...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Jiao S,Li J,Li Y,Xu Z,Kong B,Li Y,Shen Y

    更新日期:2020-11-23 00:00:00

  • Prediction of amyloid β PET positivity using machine learning in patients with suspected cerebral amyloid angiopathy markers.

    abstract::Amyloid-β(Aβ) PET positivity in patients with suspected cerebral amyloid angiopathy (CAA) MRI markers is predictive of a worse cognitive trajectory, and it provides insights into the underlying vascular pathology (CAA vs. hypertensive angiopathy) to facilitate prognostic prediction and appropriate treatment decisions....

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Jung YH,Lee H,Kim HJ,Na DL,Han HJ,Jang H,Seo SW

    更新日期:2020-11-02 00:00:00

  • TGF-β regulates Sca-1 expression and plasticity of pre-neoplastic mammary epithelial stem cells.

    abstract::The epithelial-mesenchymal plasticity, in tight association with stemness, contributes to the mammary gland homeostasis, evolution of early neoplastic lesions and cancer dissemination. Focused on cell surfaceome, we used mouse models of pre-neoplastic mammary epithelial and cancer stem cells to reveal the connection b...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Remšík J,Pícková M,Vacek O,Fedr R,Binó L,Hampl A,Souček K

    更新日期:2020-07-09 00:00:00

  • Toll-like receptor 7 deficiency protects apolipoprotein E-deficient mice from diet-induced atherosclerosis.

    abstract::Toll-like receptor 7 (TLR7) mediates autoantigen and viral RNA-induced cytokine production. Increased TLR7 expression in human atherosclerotic lesions suggests its involvement in atherogenesis. Here we demonstrated TLR7 expression in macrophages, smooth muscle cells (SMCs), and endothelial cells from mouse atheroscler...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Liu CL,Santos MM,Fernandes C,Liao M,Iamarene K,Zhang JY,Sukhova GK,Shi GP

    更新日期:2017-04-12 00:00:00

  • Differential binding affinity of tau repeat region R2 with neuronal-specific β-tubulin isotypes.

    abstract::Tau is a microtubule-associated protein whose C-terminal domain consisting of four repeat regions R1, R2, R3 and R4 binds to microtubules to stabilize them. In several neurodegenerative diseases, tau detaches from microtubules to form insoluble aggregates leading to tauopathy. Microtubules are made up of αβ tubulin su...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Bhandare VV,Kumbhar BV,Kunwar A

    更新日期:2019-07-25 00:00:00

  • Versatile multi-wavelength ultrafast fiber laser mode-locked by carbon nanotubes.

    abstract::Multi-wavelength lasers have widespread applications (e.g. fiber telecommunications, pump-probe measurements, terahertz generation). Here, we report a nanotube-mode-locked all-fiber ultrafast oscillator emitting three wavelengths at the central wavelengths of about 1540, 1550, and 1560 nm, which are tunable by stretch...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Liu X,Han D,Sun Z,Zeng C,Lu H,Mao D,Cui Y,Wang F

    更新日期:2013-01-01 00:00:00

  • Time-lapse imaging reveals highly dynamic structural maturation of postnatally born dentate granule cells in organotypic entorhino-hippocampal slice cultures.

    abstract::Neurogenesis of hippocampal granule cells (GCs) persists throughout mammalian life and is important for learning and memory. How newborn GCs differentiate and mature into an existing circuit during this time period is not yet fully understood. We established a method to visualize postnatally generated GCs in organotyp...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Radic T,Jungenitz T,Singer M,Beining M,Cuntz H,Vlachos A,Deller T,Schwarzacher SW

    更新日期:2017-03-03 00:00:00

  • Tunable graphene-based mid-infrared plasmonic wide-angle narrowband perfect absorber.

    abstract::In this paper, the periodic double-layer graphene ribbon arrays placed near a metallic ground plate coated by a dielectric layer are proposed and analyzed by the coupled-mode theory (CMT) to predict the perfect absorption response in the mid-infrared region. Numerical simulations of the finite-difference time-domain (...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Li H,Wang L,Zhai X

    更新日期:2016-11-15 00:00:00

  • Three-Dimensional Anisotropic Magnetoresistance in the Dirac Node-Line Material ZrSiSe.

    abstract::The family of materials defined as ZrSiX (X = S, Se, Te) has been established as Dirac node-line semimetals, and subsequent study is urgent to exploit the promising applications of unusual magnetoresistance (MR) properties. Herein, we systematically investigated the anisotropic MR in the newly-discovered Dirac node-li...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Pan H,Tong B,Yu J,Wang J,Fu D,Zhang S,Wu B,Wan X,Zhang C,Wang X,Song F

    更新日期:2018-06-19 00:00:00

  • In-plane Isotropic Microwave Performance of CoZr Trilayer in GHz Range.

    abstract::In this paper, we investigate the high frequency performance of Co90Zr10/SiO2/Co90Zr10 trilayers. It is demonstrated that the in-plane isotropic microwave performance is theoretically derived from the solution of the Landau-Lifshitz-Gilbert equation and experimentally achieved in that sandwich structured film. The val...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Pan L,Wang F,Wang W,Chai G,Xue D

    更新日期:2016-02-17 00:00:00

  • Association of Pre-Operative Albuminuria with Post-Operative Outcomes after Coronary Artery Bypass Grafting.

    abstract::The effect on post-operative outcomes after coronary artery bypass graft (CABG) surgery is not clear. Among 17,812 patients who underwent CABG during October 1,2006-September 28,2012 in any Department of US Veterans Affairs (VA) hospital, we identified 5,968 with available preoperative urine albumin-creatinine ratio (...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: George LK,Molnar MZ,Lu JL,Kalantar-Zadeh K,Koshy SK,Kovesdy CP

    更新日期:2015-11-09 00:00:00

  • The Arabidopsis-Trichoderma interaction reveals that the fungal growth medium is an important factor in plant growth induction.

    abstract::Trichoderma spp colonizes the plant rhizosphere and provides pathogen resistance, abiotic stress tolerance, and enhance growth and development. We evaluated the Arabidopsis-Trichoderma interaction using a split system in which Trichoderma atroviride and Trichoderma virens were grown on PDA or MS medium. Arabidopsis gr...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: González-Pérez E,Ortega-Amaro MA,Salazar-Badillo FB,Bautista E,Douterlungne D,Jiménez-Bremont JF

    更新日期:2018-11-06 00:00:00

  • Study of temporal variability of salivary cortisol and cortisone by LC-MS/MS using a new atmospheric pressure ionization source.

    abstract::There is a growing interest concerning the relevance of salivary cortisone levels in stress-related research. However, studies investigating morning patterns and day-to-day variability of cortisone versus cortisol levels are lacking. Cortisol and cortisone analysis by liquid chromatography-tandem mass spectroscopy (LC...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Bakusic J,De Nys S,Creta M,Godderis L,Duca RC

    更新日期:2019-12-17 00:00:00

  • DoOR 2.0--Comprehensive Mapping of Drosophila melanogaster Odorant Responses.

    abstract::Odors elicit complex patterns of activated olfactory sensory neurons. Knowing the complete olfactome, i.e. the responses in all sensory neurons for all relevant odorants, is desirable to understand olfactory coding. The DoOR project combines all available Drosophila odorant response data into a single consensus respon...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Münch D,Galizia CG

    更新日期:2016-02-25 00:00:00

  • Polyphenols (S3) Isolated from Cone Scales of Pinus koraiensis Alleviate Decreased Bone Formation in Rat under Simulated Microgravity.

    abstract::In order to screen out an effective bone loss protectant from natural plant polyphenol and to elucidate the mechanism of the plant polyphenols that alleviate bone loss under simulated microgravity, the proliferation activities of 9 total polyphenol extracts from natural product (TPENP) on osteoblasts were measured. Po...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Diao Y,Chen B,Wei L,Wang Z

    更新日期:2018-08-24 00:00:00

  • Diagnostic accuracy of tomosynthesis-guided vacuum assisted breast biopsy of ultrasound occult lesions.

    abstract::This study aims to evaluate the diagnostic accuracy of digital breast tomosynthesis-guided vacuum assisted breast biopsy (DBT-VABB) of screening detected suspicious mammographic abnormalities comprising of calcifications, asymmetric densities, architectural distortions and spiculated masses. In this institutionally ap...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Bohan S,Ramli Hamid MT,Chan WY,Vijayananthan A,Ramli N,Kaur S,Rahmat K

    更新日期:2021-01-08 00:00:00

  • Humanization of Antibodies using a Statistical Inference Approach.

    abstract::Antibody humanization is a key step in the preclinical phase of the development of therapeutic antibodies, originally developed and tested in non-human models (most typically, in mouse). The standard technique of Complementarity-Determining Regions (CDR) grafting into human Framework Regions of germline sequences has ...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Clavero-Álvarez A,Di Mambro T,Perez-Gaviro S,Magnani M,Bruscolini P

    更新日期:2018-10-04 00:00:00

  • Evolution of deceptive and true courtship songs in moths.

    abstract::Ultrasonic mating signals in moths are argued to have evolved via exploitation of the receivers' sensory bias towards bat echolocation calls. We have demonstrated that female moths of the Asian corn borer are unable to distinguish between the male courtship song and bat calls. Females react to both the male song and b...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Nakano R,Takanashi T,Surlykke A,Skals N,Ishikawa Y

    更新日期:2013-01-01 00:00:00

  • Energy of injection-induced seismicity predicted from in-situ experiments.

    abstract::The ability to predict the magnitude of an earthquake caused by deep fluid injections is an important factor for assessing the safety of the reservoir storage and the seismic hazard. Here, we propose a new approach to evaluate the seismic energy released during fluid injection by integrating injection parameters, indu...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: De Barros L,Cappa F,Guglielmi Y,Duboeuf L,Grasso JR

    更新日期:2019-03-21 00:00:00

  • Identification and characterization of SEC24D as a susceptibility gene for hepatitis B virus infection.

    abstract::Single nucleotide polymorphisms (SNPs) and genes associated with susceptibility to hepatitis B virus (HBV) infection that have been identified by genome-wide association studies explain only a limited portion of the known heritability, indicating more genetic variants remain to be discovered. In this study, we adopted...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Jiang X,Zhang B,Zhao J,Xu Y,Han H,Su K,Tao J,Fan R,Zhao X,Li L,Li MD

    更新日期:2019-09-17 00:00:00

  • Geometric quantum discord of Heisenberg model with dissipative terms.

    abstract::In this paper, we study a system with two interacting qubits described by the Heisenberg model with dissipative terms, and analyze decay dynamics and the steady-state of geometric quantum discords. Our results indicate that we can ignore the interaction force in the z-direction and adjust the parameters to change the ...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Liang J,Zhang C

    更新日期:2020-07-02 00:00:00

  • Closed-form solutions and scaling laws for Kerr frequency combs.

    abstract::A single closed-form analytical solution of the driven nonlinear Schrödinger equation is developed, reproducing a large class of the behaviors in Kerr-comb systems, including bright-solitons, dark-solitons, and a large class of periodic wavetrains. From this analytical framework, a Kerr-comb area theorem and a pump-de...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Renninger WH,Rakich PT

    更新日期:2016-04-25 00:00:00

  • Graft revascularization is essential for non-invasive monitoring of transplanted islets with radiolabeled exendin.

    abstract::Islet transplantation is a novel promising strategy to cure type 1 diabetes. However, the long-term outcome is still poor, because both function and survival of the transplant decline over-time. Non-invasive imaging methods have the potential to enable monitoring of islet survival after transplantation and the effects...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Eter WA,Bos D,Frielink C,Boerman OC,Brom M,Gotthardt M

    更新日期:2015-10-22 00:00:00

  • The adaptive value of camouflage and colour change in a polymorphic prawn.

    abstract::Camouflage has been a textbook example of natural selection and adaptation since the time of the earliest evolutionists. However, aside from correlational evidence and studies using artificial dummy prey, experiments directly showing that better camouflaged prey to predator vision are at reduced risk of attack are lac...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Duarte RC,Stevens M,Flores AAV

    更新日期:2018-10-30 00:00:00

  • Author Correction: Dogs and humans respond to emotionally competent stimuli by producing different facial actions.

    abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误


    authors: Caeiro C,Guo K,Mills D

    更新日期:2018-07-05 00:00:00

  • Modelling survival: exposure pattern, species sensitivity and uncertainty.

    abstract::The General Unified Threshold model for Survival (GUTS) integrates previously published toxicokinetic-toxicodynamic models and estimates survival with explicitly defined assumptions. Importantly, GUTS accounts for time-variable exposure to the stressor. We performed three studies to test the ability of GUTS to predict...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Ashauer R,Albert C,Augustine S,Cedergreen N,Charles S,Ducrot V,Focks A,Gabsi F,Gergs A,Goussen B,Jager T,Kramer NI,Nyman AM,Poulsen V,Reichenberger S,Schäfer RB,Van den Brink PJ,Veltman K,Vogel S,Zimmer EI,Preuss

    更新日期:2016-07-06 00:00:00