Lipid-II Independent Antimicrobial Mechanism of Nisin Depends On Its Crowding And Degree Of Oligomerization.

abstract：:Thermoelectric properties of Graphene nano-ribbons (GNRs) with nanopores (NPs) are explored for a range of pore dimensions in order to achieve a high performance two-dimensional nano-scale thermoelectric device. We reduce thermal conductivity of GNRs by introducing pores in them in order to enhance their thermoelectri...

journal_title：Scientific reports

authors： Hossain MS,Al-Dirini F,Hossain FM,Skafidas E

更新日期：2015-06-17 00:00:00

abstract：:Knowledge of the structure-property-function relationship of humic substances (HSs) is key for understanding their role in soil. Despite progress, studies on this topic are still under discussion. We analyzed 37 humic fractions with respect to their isotopic composition, structural characteristics, and properties resp...

journal_title：Scientific reports

authors： García AC,de Souza LG,Pereira MG,Castro RN,García-Mina JM,Zonta E,Lisboa FJ,Berbara RL

更新日期：2016-02-10 00:00:00

abstract：:Labeling nuclear proteins with electron dense probes in living cells has been a major challenge due to their inability to penetrate into nuclei. We developed a lipid-based approach for delivering antibodies coupled to 0.8 nm ultrasmall gold particles into the nucleus to label RNA polymerase II. Focussed Ion Beam slici...

journal_title：Scientific reports

authors： Orlov I,Schertel A,Zuber G,Klaholz B,Drillien R,Weiss E,Schultz P,Spehner D

更新日期：2015-02-09 00:00:00

abstract：:Lonicera japonica Thunb, rich in chlorogenic acid (CHA), is used for viral upper respiratory tract infection treatment caused by influenza virus, parainfluenza virus, and respiratory syncytial virus, ect in China. It was reported that CHA reduced serum hepatitis B virus level and death rate of influenza virus-infected...

journal_title：Scientific reports

authors： Ding Y,Cao Z,Cao L,Ding G,Wang Z,Xiao W

更新日期：2017-04-10 00:00:00

abstract：:Cholangiocarcinoma (CCA) represents a rare form of primary liver cancer with increasing incidence but dismal prognosis. Surgical treatment has remained the only potentially curative treatment option, but it remains unclear which patients benefit most from liver surgery, highlighting the need for new preoperative strat...

journal_title：Scientific reports

authors： Loosen SH,Roderburg C,Kauertz KL,Koch A,Vucur M,Schneider AT,Binnebösel M,Ulmer TF,Lurje G,Schoening W,Tacke F,Trautwein C,Longerich T,Dejong CH,Neumann UP,Luedde T

更新日期：2017-12-05 00:00:00

abstract：:Biological armors such as mollusk shells have long been recognized and studied for their values in inspiring novel designs of engineering materials with higher toughness and strength. However, no material is invincible and biological armors also have their rivals. In this paper, our attention is focused on the teeth o...

journal_title：Scientific reports

authors： Fu J,He C,Xia B,Li Y,Feng Q,Yin Q,Shi X,Feng X,Wang H,Yao H

更新日期：2016-03-22 00:00:00

abstract：:Male moths use species-specific sex pheromones to identify and orientate toward conspecific females. Odorant receptors (ORs) for sex pheromone substances have been identified as sex pheromone receptors in various moth species. However, direct in vivo evidence linking the functional role of these ORs with behavioural r...

journal_title：Scientific reports

authors： Sakurai T,Mitsuno H,Mikami A,Uchino K,Tabuchi M,Zhang F,Sezutsu H,Kanzaki R

更新日期：2015-06-05 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Ghazizadeh E,Moosavifard SE,Daneshmand N,Kaverlavani SK

更新日期：2020-08-11 00:00:00

abstract：:Vaccine trials and cohort studies in Plasmodium falciparum endemic areas indicate that naturally-acquired and vaccine-induced antibodies to merozoite surface protein 2 (MSP2) are associated with resistance to malaria. These data indicate that PfMSP2 has significant potential as a component of a multi-antigen malaria v...

journal_title：Scientific reports

authors： Eacret JS,Gonzales DM,Franks RG,Burns JM Jr

更新日期：2019-06-21 00:00:00

abstract：:Diffusion magnetic resonance imaging (dMRI) proved promising in patients with non-myelopathic degenerative cervical cord compression (NMDCCC), i.e., without clinically manifested myelopathy. Aim of the study is to present a fast multi-shell HARDI-ZOOMit dMRI protocol and validate its usability to detect microstructura...

journal_title：Scientific reports

authors： Labounek R,Valošek J,Horák T,Svátková A,Bednařík P,Vojtíšek L,Horáková M,Nestrašil I,Lenglet C,Cohen-Adad J,Bednařík J,Hluštík P

更新日期：2020-10-16 00:00:00

abstract：:Endothelial cells respond to changes in subendothelial stiffness by altering their migration and mechanics, but whether those responses are due to transcriptional reprogramming remains largely unknown. We measured traction force generation and also performed gene expression profiling for two endothelial cell types gro...

journal_title：Scientific reports

authors： Bastounis EE,Yeh YT,Theriot JA

更新日期：2019-12-03 00:00:00

abstract：:The immune checkpoint based therapy targeting the programmed death-1 (PD-1) receptor and its PD-L1 ligand has recently been approved for the therapy of different malignant conditions, but not yet for gastroenteropancreatic neuroendocrine tumors (GEP-NETs). In this context, we evaluated the expression of PD-1 and PD-L1...

journal_title：Scientific reports

authors： Sampedro-Núñez M,Serrano-Somavilla A,Adrados M,Cameselle-Teijeiro JM,Blanco-Carrera C,Cabezas-Agricola JM,Martínez-Hernández R,Martín-Pérez E,Muñoz de Nova JL,Díaz JÁ,García-Centeno R,Caneiro-Gómez J,Abdulkader I,González-Amaro

更新日期：2018-12-13 00:00:00

abstract：:Practical alternatives to gold-standard measures of circadian timing in shift workers are needed. We assessed the feasibility of applying a limit-cycle oscillator model of the human circadian pacemaker to estimate circadian phase in 25 nursing and medical staff in a field setting during a transition from day/evening s...

journal_title：Scientific reports

authors： Stone JE,Aubert XL,Maass H,Phillips AJK,Magee M,Howard ME,Lockley SW,Rajaratnam SMW,Sletten TL

更新日期：2019-07-30 00:00:00

abstract：:We have measured artificial radionuclides, such as 90Sr and 137Cs, in atmospheric depositions since 1957 in Japan. We observed the variations in 90Sr and 137Cs, which were emitted from atmospheric nuclear tests and nuclear power plant accidents, due to their diffusion, deposition, and resuspension. In March 2011, the ...

journal_title：Scientific reports

authors： Kinase T,Adachi K,Sekiyama TT,Kajino M,Zaizen Y,Igarashi Y

更新日期：2020-12-10 00:00:00

abstract：:Platelet aggregation and adhesion are critically involved in both normal hemostasis and thrombosis during vascular injury. Before any surgery, it is important to identify the number of platelets and their functionality to reduce the risk of bleeding; therefore, platelet function testing is a requirement. We introduce ...

journal_title：Scientific reports

authors： Jeon HJ,Qureshi MM,Lee SY,Badadhe JD,Cho H,Chung E

更新日期：2019-11-11 00:00:00

abstract：:The synthesis and subsequent genomic integration of DNA that is complementary to the genomes of non-retroviral RNA viruses are rarely observed. However, upon infection of various human cell lines and primary fibroblasts with the vesicular stomatitis virus (VSV), we detected DNA complementary to the VSV RNA. The VSV DN...

journal_title：Scientific reports

authors： Shimizu A,Nakatani Y,Nakamura T,Jinno-Oue A,Ishikawa O,Boeke JD,Takeuchi Y,Hoshino H

更新日期：2014-05-30 00:00:00

abstract：:We investigate the timescales of the horizontal mass flux decay of wind remobilised volcanic particles in Argentina, associated with the tephra-fallout deposit produced by the 2011-2012 Cordón Caulle (Chile) eruption. Particle removal processes are controlled by complex interactions of meteorological conditions, surfa...

journal_title：Scientific reports

authors： Dominguez L,Rossi E,Mingari L,Bonadonna C,Forte P,Panebianco JE,Bran D

更新日期：2020-09-02 00:00:00

abstract：:Connectivity is fundamentally important for shaping the resilience of complex human and natural networks when systems are disturbed. Ecosystem resilience is, in part, shaped by the spatial arrangement of habitats, the permeability and fluxes between them, the stabilising functions performed by organisms, their dispers...

journal_title：Scientific reports

authors： Pearson RM,Schlacher TA,Jinks KI,Olds AD,Brown CJ,Connolly RM

更新日期：2021-01-13 00:00:00

abstract：:Extracellular signal-regulated kinase (ERK) is a member of the family of mitogen-activated protein kinases (MAPKs) and coordinately regulates a multitude of cellular processes. In response to a variety of extracellular stimuli, phosphorylation of both threonine and tyrosine residues activates ERK. Recent evidence indi...

journal_title：Scientific reports

authors： Kurioka T,Matsunobu T,Satoh Y,Niwa K,Endo S,Fujioka M,Shiotani A

更新日期：2015-11-18 00:00:00

abstract：:Accumulating evidence indicates that cancer cells show specific alterations in phospholipid metabolism that contribute to tumour progression in several types of cancer, including colorectal cancer. Questions still remain as to what lipids characterize the outer edge of cancer tissues and whether those cancer outer edg...

journal_title：Scientific reports

authors： Hiraide T,Ikegami K,Sakaguchi T,Morita Y,Hayasaka T,Masaki N,Waki M,Sugiyama E,Shinriki S,Takeda M,Shibasaki Y,Miyazaki S,Kikuchi H,Okuyama H,Inoue M,Setou M,Konno H

更新日期：2016-07-20 00:00:00

abstract：:Hydrogels have been developed and applied to various biomedical applications due to their biocompatibility. However, understanding of modulation between cells to hydrogel interface is still unclear, and parameters to explain the interaction are not sophisticated enough. In this report, we studied the effect of polymer...

journal_title：Scientific reports

authors： Lee J,Song B,Subbiah R,Chung JJ,Choi UH,Park K,Kim SH,Oh SJ

更新日期：2019-02-21 00:00:00

abstract：:In total, 303 randomly selected clinical Mycobacterium tuberculosis (MTB) isolates from 303 patients (collected January to December 2012) in central Taiwan were examined. The major lineages found were Beijing (N = 114, 37.62%), Haarlem (N = 76, 25.08%) and East African-Indian (EAI) (N = 42, 13.86%). Notably, younger p...

journal_title：Scientific reports

authors： Chen YY,Chang JR,Wu CD,Yeh YP,Yang SJ,Hsu CH,Lin MC,Tsai CF,Lin MS,Su IJ,Dou HY

更新日期：2017-07-14 00:00:00

abstract：:The origin and domestication of cultivated barley have long been under debate. A population-based resequencing and phylogenetic analysis of the single copy of RPB2 gene was used to address barley domestication, to explore genetic differentiation of barley populations on the worldwide scale, and to understand gene-pool...

journal_title：Scientific reports

authors： Wang Y,Ren X,Sun D,Sun G

更新日期：2016-10-27 00:00:00

abstract：:We introduce a compact, fast large area multiphoton exoscope (FLAME) system with enhanced molecular contrast for macroscopic imaging of human skin with microscopic resolution. A versatile imaging platform, FLAME combines optical and mechanical scanning mechanisms with deep learning image restoration to produce depth-r...

journal_title：Scientific reports

authors： Fast A,Lal A,Durkin AF,Lentsch G,Harris RM,Zachary CB,Ganesan AK,Balu M

更新日期：2020-10-22 00:00:00

abstract：:Integrative and conjugative elements (ICEs) are mobile genetic elements that contribute to horizontal gene transfer. The aim of this work was to study different types of ICEs in clinical isolates of the emergent pathogen Shewanella spp., to compare their transfer efficiency and their ability to integrate a new host. H...

journal_title：Scientific reports

authors： Parmeciano DI Noto G,Iriarte A,Ramírez MS,Centrón D,Quiroga C

更新日期：2019-05-29 00:00:00

abstract：:The Morris Water Maze is a widely used task in studies of spatial learning with rodents. Classical performance measures of animals in the Morris Water Maze include the escape latency, and the cumulative distance to the platform. Other methods focus on classifying trajectory patterns to stereotypical classes representi...

journal_title：Scientific reports

authors： Gehring TV,Luksys G,Sandi C,Vasilaki E

更新日期：2015-10-01 00:00:00

abstract：:Test anxiety is a condition in which people experience extreme distress and anxiety before and in test situations. It affects up to 40 percent of all students. Conventional treatment includes both medication and psychotherapy, but studies also demonstrated that placebos affect anxiety symptoms. Although in the traditi...

journal_title：Scientific reports

authors： Schaefer M,Denke C,Harke R,Olk N,Erkovan M,Enge S

更新日期：2019-09-16 00:00:00

abstract：:We utilized size-tunable gold nanoparticles (Au NPs) to investigate the toxicogenomic responses of the model organism Caenorhabditis elegans. We demonstrated that the nematode C. elegans can uptake Au NPs coated with or without 11-mercaptoundecanoic acid (MUA), and Au NPs are detectable in worm intestines using X-ray ...

journal_title：Scientific reports

authors： Hu CC,Wu GH,Lai SF,Muthaiyan Shanmugam M,Hwu Y,Wagner OI,Yen TJ

更新日期：2018-10-15 00:00:00

abstract：:Methylacetoin (3-hydroxy-3-methylbutan-2-one) and 2-methyl-2,3-butanediol are currently obtained exclusively via chemical synthesis. Here, we report, to the best of our knowledge, the first alternative route, using engineered Escherichia coli. The biological synthesis of methylacetoin was first accomplished by reversi...

journal_title：Scientific reports

authors： Jiang X,Zhang H,Yang J,Zheng Y,Feng D,Liu W,Xu X,Cao Y,Zou H,Zhang R,Cheng T,Jiao F,Xian M

更新日期：2013-01-01 00:00:00

abstract：:Maternal obesity in pregnancy increases the risk of adverse long-term health outcomes in both mother and offspring. A population-based cohort of prospectively collected routine antenatal healthcare data collected between January 2003 and September 2017 at University Hospital Southampton, UK was utilised to investigate...

journal_title：Scientific reports

authors： Ziauddeen N,Roderick PJ,Macklon NS,Alwan NA

更新日期：2019-06-24 00:00:00