Abstract:
:Daily rhythmic changes are found in cellular events in cell cycle, DNA repair, apoptosis and angiogenesis in both normal and tumour tissue, as well as in enzymatic activity and drug metabolism. In this paper, we hypothesize that circadian rhythms need to be considered in radiation protection and optimization in personalized medicine, especially for paediatric care. The sensitivity of the eye lens to ionizing radiation makes the case for limiting damage to the lens epithelium by planning medical radio-imaging procedures for the afternoon, rather than the morning. Equally, the tumour and normal tissue response to radiotherapy is also subject to diurnal variation enabling optimization of time of treatment.
journal_name
Radiat Prot Dosimetryjournal_title
Radiation protection dosimetryauthors
Forssell-Aronsson E,Quinlan RAdoi
10.1093/rpd/ncw328subject
Has Abstractpub_date
2017-04-01 00:00:00pages
16-20issue
1-3eissn
0144-8420issn
1742-3406pii
ncw328journal_volume
173pub_type
杂志文章abstract::The three general principles of the International Commission on Radiological Protection (ICRP) are: justification, optimisation (ALARA) and dose limitation. The principle application of optimisation (ALARA) for occupational exposures of workers or the public to external radiation is reliant on low doses being assessed...
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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更新日期:2005-01-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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journal_title:Radiation protection dosimetry
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更新日期:2017-04-20 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncz032
更新日期:2019-12-31 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncn237
更新日期:2008-01-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncaa143
更新日期:2020-11-27 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006848
更新日期:2002-01-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006047
更新日期:2002-01-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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更新日期:2006-01-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncr089
更新日期:2011-05-01 00:00:00
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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更新日期:2004-01-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 历史文章,杂志文章,评审
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006656
更新日期:2001-01-01 00:00:00
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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更新日期:2020-06-24 00:00:00
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncw026
更新日期:2016-09-01 00:00:00