Supine linac treatment versus tomotherapy in craniospinal irradiation: planning comparison and dosimetric evaluation.

Abstract:

:Craniospinal irradiation (CSI) is the standard treatment of primary intracranial tumour with risk of leptomeningeal dissemination. However, supine setup field-in-field technique does not need inter-fractional junction shift. Recently, the studies of CSI with tomotherapy showed excellent target coverage and tolerable normal organ dose in paediatric patients. The planning comparison and dosimetric difference between conventional radiotherapy and tomotherapy are presented. Three patients with central nervous system germinoma received supine CSI treatment. Normal tissue complication probability calculation was performed for parotid gland, kidney, lens, small bowel, ovary and testis. Homogenous vertebral body coverage for tomotherapy compared with conformal radiotherapy was found. The mean dose to each parotid gland decreased by 7.3 and 10 Gy, respectively, with tomotherapy. The volume of oesophagus and small bowel receiving >10 Gy was significantly lower. The V2, V5, V10 and V20 of the lungs are 81.6, 12.4, 2.3 and 0 % with tomotherapy. Tomotherapy showed excellent homogenous dose distribution through the craniospinal axis (PTV) and higher conformity index.

journal_name

Radiat Prot Dosimetry

authors

Hong JY,Kim GW,Kim CU,Cheon GS,Son SH,Lee JY,Lee YH,Lee JH,Choi BO,Kim YS,Lee SN,Jang HS,Kang YN,Yoon SC

doi

10.1093/rpd/ncr190

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

364-6

issue

1-3

eissn

0144-8420

issn

1742-3406

pii

ncr190

journal_volume

146

pub_type

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