T-cell exhaustion in tuberculosis: pitfalls and prospects.

abstract：:Riboflavin derivatives are essential cofactors for a myriad of flavoproteins. In bacteria, flavins importance extends beyond their role as intracellular protein cofactors, as secreted flavins are a key metabolite in a variety of physiological processes. Bacteria obtain riboflavin through the endogenous riboflavin bios...

journal_title：Critical reviews in microbiology

authors： García-Angulo VA

更新日期：2017-03-01 00:00:00

abstract：:Staphylococcus aureus biofilms represent a unique micro-environment that directly contribute to the bacterial fitness within hospital settings. The accumulation of this structure on implanted medical devices has frequently caused the development of persistent and chronic S. aureus-associated infections, which represen...

journal_title：Critical reviews in microbiology

authors： Figueiredo AMS,Ferreira FA,Beltrame CO,Côrtes MF

更新日期：2017-09-01 00:00:00

abstract：:Due to the rise of multidrug-resistant infections in humans, phage therapy is gaining renewed attention in Western medicine. Despite the increasing number of publications focussed on the isolation, characterization and in vitro performance of different phages, there is still a lack of concise pre-clinical information ...

journal_title：Critical reviews in microbiology

authors： Melo LDR,Oliveira H,Pires DP,Dabrowska K,Azeredo J

更新日期：2020-02-01 00:00:00

abstract：:Following a brief review of the ecology of Escherichia coli in general, the role of Shiga-Toxigenic (Verocytotoxigenic) E. coli (STEC) as pathogens is addressed. While STEC belonging to the serogroup O157 have been extensively studied and shown to be involved in many cases and outbreaks of human disease, the importanc...

journal_title：Critical reviews in microbiology

authors： Bettelheim KA

更新日期：2007-01-01 00:00:00

abstract：:Eugenol is a hydroxyphenyl propene, naturally occurring in the essential oils of several plants belonging to the Lamiaceae, Lauraceae, Myrtaceae, and Myristicaceae families. It is one of the major constituents of clove (Syzygium aromaticum (L.) Merr. & L.M. Perry, Myrtaceae) oil and is largely used in both foods and c...

journal_title：Critical reviews in microbiology

authors： Marchese A,Barbieri R,Coppo E,Orhan IE,Daglia M,Nabavi SF,Izadi M,Abdollahi M,Nabavi SM,Ajami M

更新日期：2017-11-01 00:00:00

abstract：:It is clear that mannan has the potential to influence multiple biologic functions in vivo and in vitro, including both mannan-specific and mannan-nonspecific activities. Based on in vitro studies, various mechanisms have been proposed for the regulatory activities observed, ranging from interference with normal PMNL ...

journal_title：Critical reviews in microbiology

authors： Domer JE

更新日期：1989-01-01 00:00:00

abstract：:The use of many rapid detection technologies could be expanded if the bacteria were separated, concentrated, and purified from the sample matrix before detection. Specific advantages of bacterial concentration might include facilitating the detection of multiple bacterial strains; removal of matrix-associated assay in...

journal_title：Critical reviews in microbiology

authors： Stevens KA,Jaykus LA

更新日期：2004-01-01 00:00:00

abstract：:Antibiotic resistance in Gram-negative pathogens has emerged and constituted a global crisis, thereby novel antibiotics and other anti-infective strategies are urgently needed. However, the growing gap between clinical need and drug innovation, coupled with the membrane permeability barrier in Gram-negative bacteria r...

journal_title：Critical reviews in microbiology

authors： Liu Y,Li R,Xiao X,Wang Z

更新日期：2019-05-01 00:00:00

abstract：:The cell wall of Saccharomyces cerevisiae is an extracellular organelle crucial for preserving its cellular integrity and detecting environmental cues. The cell wall is composed of mannoproteins attached to a polysaccharide network and is continuously remodelled as cells undergo cell division, mating, gametogenesis or...

journal_title：Critical reviews in microbiology

authors： Novačić A,Vučenović I,Primig M,Stuparević I

更新日期：2020-02-01 00:00:00

abstract：:Brucellosis is a worldwide zoonosis causing reproductive failures in livestock and a severe multi-organ disease in humans. The genus Brucella is divided into seven species and various biotypes differing in pathogenicity and host specificity. Although Brucella spp. represent a highly homogenous group of bacteria, RFLPs...

journal_title：Critical reviews in microbiology

authors： Al Dahouk S,Tomaso H,Prenger-Berninghoff E,Splettstoesser WD,Scholz HC,Neubauer H

更新日期：2005-01-01 00:00:00

abstract：:The first Alicyclobacillus spp. was isolated in 1982, and was originally thought to be strictly limited to thermophilic and acidic environments. Two years later, another Alicyclobacillus sp., A. acidoterrestris, was identified as the causative agent in spoilage of commercially pasteurized apple juice. Subsequent studi...

journal_title：Critical reviews in microbiology

authors： Chang SS,Kang DH

更新日期：2004-01-01 00:00:00

abstract：:Urease activity is a physiological function of many bacteria that enables these organisms to utilize urea as a source of nitrogen. The association of ureolytic bacteria with human or animal hosts varies widely from a commensal relationship as demonstrated with skin microflora, a symbiotic relationship in the gastroint...

journal_title：Critical reviews in microbiology

authors： McLean RJ,Nickel JC,Cheng KJ,Costerton JW

更新日期：1988-01-01 00:00:00

abstract：:Humans ingest large numbers of microbes daily. Food provides distinctly different physical and physiological conditions from drinking water. With high concentrations of carbohydrate, protein, and ionic strength, food is much closer to the human physiological state than drinking water, which is essentially devoid of nu...

journal_title：Critical reviews in microbiology

authors： Wadhwa SG,Khaled GH,Edberg SC

更新日期：2002-01-01 00:00:00

abstract：:The female genital tract is an intricate, yet balanced ecosystem that hosts a variety of different residential microflora. The physiological changes that occur during pregnancy may disrupt this balanced ecosystem and predispose women to a potentially pathogenic microbiota. Bacteria that are associated with bacterial v...

journal_title：Critical reviews in microbiology

authors： Redelinghuys MJ,Ehlers MM,Dreyer AW,Kock MM

更新日期：2016-05-01 00:00:00

abstract：:Within Gram-positive bacteria, the expression of target genes is controlled at the population level via signaling peptides, also known as pheromones. Pheromones control a wide range of functions, including competence, virulence, and others that remain unknown. Until now, their role in bacterial gene regulation has pro...

journal_title：Critical reviews in microbiology

authors： Monnet V,Juillard V,Gardan R

更新日期：2016-05-01 00:00:00

abstract：:The immune system is well-equipped with sensors that detect invading pathogens and dictate subsequent immune responses for clearing the infections. One such class of sensor is the toll-like receptor (TLR), that can sense diverse molecules of pathogen origin such as proteins, lipids, carbohydrate, DNA, RNA, and trigger...

journal_title：Critical reviews in microbiology

authors： Udgata A,Dolasia K,Ghosh S,Mukhopadhyay S

更新日期：2019-05-01 00:00:00

abstract：:The increasing emergence of antimicrobial multiresistant bacteria is of great concern to public health. While these bacteria are becoming an ever more prominent cause of nosocomial and community-acquired infections worldwide, the antibiotic discovery pipeline has been stalled in the last few years with very few effort...

journal_title：Critical reviews in microbiology

authors： Cardona ST,Selin C,Gislason AS

更新日期：2015-01-01 00:00:00

abstract：:Giardia lamblia is the causative agent of the diarrheal disease giardiasis, against which only a limited number of drugs are currently available. Increasing reports of resistance to these drugs makes it necessary to identify new cellular targets for designing the next generation of anti-giardial drugs. Towards this go...

journal_title：Critical reviews in microbiology

authors： Ray A,Sarkar S

更新日期：2017-08-01 00:00:00

abstract：:The exact aetiology of most autoimmune diseases remains unknown, nonetheless, several factors contributing to the induction or exacerbation of autoimmune reactions have been suggested. These include the genetic profile and lifestyle of the affected individual in addition to environmental triggers such as bacterial, pa...

journal_title：Critical reviews in microbiology

authors： Hussein HM,Rahal EA

更新日期：2019-08-01 00:00:00

abstract：:With the increase in antibiotic-resistant bacteria and the lack of new antibiotics being brought onto the market, alternative strategies need to be found to cope with infections resulting from drug-resistant bacteria. A possible solution may be to combine existing antibiotics with phytochemicals to enhance the efficac...

journal_title：Critical reviews in microbiology

authors： Langeveld WT,Veldhuizen EJ,Burt SA

更新日期：2014-02-01 00:00:00

abstract：:Nanotechnology has revolutionized almost all the fields of science and technology, particularly the food packaging industry. Accordingly, some nanoparticles can be used in food contact materials to preserve food products for longer periods. To date, many inorganic and metal nanoparticles have been implemented to synth...

journal_title：Critical reviews in microbiology

authors： Hoseinnejad M,Jafari SM,Katouzian I

更新日期：2018-03-01 00:00:00

abstract：:Microbially synthesized iron oxide nanoparticles (FeONPs) hold great potential for biomedical, clinical, and environmental applications owing to their several unique features. Biomineralization, a process that exists in almost every living organism playing a significant role in the fabrication of FeONPs through the in...

journal_title：Critical reviews in microbiology

authors： Ashraf N,Ahmad F,Da-Wei L,Zhou RB,Feng-Li H,Yin DC

更新日期：2019-05-01 00:00:00

abstract：:Toxic shock syndrome (TSS) was first described in 1978 and since that year over 2990 cases have been reported to the Communicable Disease Center. The estimated case-fatality rate is 5.6%. The disease is characterized by fever, hypotension, rash, desquamation, and involvement of at least three other organ systems. Appr...

journal_title：Critical reviews in microbiology

authors： Quimby F,Nguyen HT

更新日期：1985-01-01 00:00:00

abstract：:Both coagulation and fibrinolysis are tightly connected with the innate immune system. Infection and inflammation cause profound alterations in the otherwise well-controlled balance between coagulation and fibrinolysis. Many pathogenic bacteria directly exploit the host's hemostatic system to increase their virulence....

journal_title：Critical reviews in microbiology

authors： Peetermans M,Vanassche T,Liesenborghs L,Lijnen RH,Verhamme P

更新日期：2016-11-01 00:00:00

abstract：:Enteroaggregative Escherichia coli heat-stable enterotoxin 1 (EAST1) is a small protein that was first detected more than a decade ago in an enteroaggregative E. coli (EAEC) strain isolated from the stools of a diarrheic child. The EAST1 gene, astA, is not solely present in EAEC, but also in other categories of diarrh...

journal_title：Critical reviews in microbiology

authors： Ménard LP,Dubreuil JD

更新日期：2002-01-01 00:00:00

abstract：:Highly significant evidence of the intellectual and cultural efforts of the human race is contained in documents. They take many forms, from papyri through paper to modern magnetic media and optical records. These items are mainly made of organic materials many of which contain polymers, which span from cellulose and ...

journal_title：Critical reviews in microbiology

authors： Cappitelli F,Sorlini C

更新日期：2005-01-01 00:00:00

abstract：:Heavy metal contamination has become a worldwide environmental concern due to its toxicity, non-degradability and food-chain bioaccumulation. Conventional physical and chemical treatment methods for heavy metal removal have disadvantages such as cost-intensiveness, incomplete removal, secondary pollution and the lack ...

journal_title：Critical reviews in microbiology

authors： Li PS,Tao HC

更新日期：2015-06-01 00:00:00

abstract：:Lipases are esterases able to hydrolyze water-insoluble esters such as long-chain triglycerides. These enzymes also catalyze the formation of esters (esterification) and the exchange of ester bonds (transesterification) when present in nonaqueous media. Lipases display a high degree of specificity and enantioselectivi...

journal_title：Critical reviews in microbiology

authors： Soberón-Chávez G,Palmeros B

更新日期：1994-01-01 00:00:00

abstract：:A pheromone is a chemical excreted by an organism into the environment that acts to elicit a specific response from other organisms of the same species. The importance of pheromones in the life cycle of various species of mammals, insects, and fungi is well known. In the past decade, it has become apparent that pherom...

journal_title：Critical reviews in microbiology

authors： Stephens K

更新日期：1986-01-01 00:00:00

abstract：:The numbers and diversity of microbes in ecosystems within and around us is unmatched, yet most of these microorganisms remain recalcitrant to in vitro cultivation. Various high-throughput molecular techniques, collectively termed multi-omics, provide insights into the genomic structure and metabolic potential as well...

journal_title：Critical reviews in microbiology

authors： Gutleben J,Chaib De Mares M,van Elsas JD,Smidt H,Overmann J,Sipkema D

更新日期：2018-03-01 00:00:00