Dribbling through the host defence: targeting the TLRs by pathogens.

abstract：:The female genital tract is an intricate, yet balanced ecosystem that hosts a variety of different residential microflora. The physiological changes that occur during pregnancy may disrupt this balanced ecosystem and predispose women to a potentially pathogenic microbiota. Bacteria that are associated with bacterial v...

journal_title：Critical reviews in microbiology

authors： Redelinghuys MJ,Ehlers MM,Dreyer AW,Kock MM

更新日期：2016-05-01 00:00:00

abstract：:Humans ingest large numbers of microbes daily. Food provides distinctly different physical and physiological conditions from drinking water. With high concentrations of carbohydrate, protein, and ionic strength, food is much closer to the human physiological state than drinking water, which is essentially devoid of nu...

journal_title：Critical reviews in microbiology

authors： Wadhwa SG,Khaled GH,Edberg SC

更新日期：2002-01-01 00:00:00

abstract：:Resuscitation promoting factors (Rpf) are peptidoglycan-hydrolyzing enzymes that are pivotal in the resuscitation of quiescent actinobacteria including Mycobacterium tuberculosis. From the published data, it is clear that Rpf are required for the resuscitation of non-replicating bacilli and pathogenesis in murine infe...

journal_title：Critical reviews in microbiology

authors： Rosser A,Stover C,Pareek M,Mukamolova GV

更新日期：2017-09-01 00:00:00

abstract：:Heavy metal contamination has become a worldwide environmental concern due to its toxicity, non-degradability and food-chain bioaccumulation. Conventional physical and chemical treatment methods for heavy metal removal have disadvantages such as cost-intensiveness, incomplete removal, secondary pollution and the lack ...

journal_title：Critical reviews in microbiology

authors： Li PS,Tao HC

更新日期：2015-06-01 00:00:00

abstract：:Enteroaggregative Escherichia coli heat-stable enterotoxin 1 (EAST1) is a small protein that was first detected more than a decade ago in an enteroaggregative E. coli (EAEC) strain isolated from the stools of a diarrheic child. The EAST1 gene, astA, is not solely present in EAEC, but also in other categories of diarrh...

journal_title：Critical reviews in microbiology

authors： Ménard LP,Dubreuil JD

更新日期：2002-01-01 00:00:00

abstract：:This review followed from experiments suggesting that some fungi do not require calcium. It was found that many studies of a calcium requirement in microorganisms had assumed specificity for chelation agents such as EGTA and A23187, which the reagents did not possess. Early studies still cited today often preceded the...

journal_title：Critical reviews in microbiology

authors： Youatt J

更新日期：1993-01-01 00:00:00

abstract：:Escherichia coli can commonly be found, either as a commensal, probiotic or a pathogen, in the human gastrointestinal (GI) tract. Biofilm formation and its regulation is surprisingly variable, although distinct regulatory pattern of red, dry and rough (rdar) biofilm formation arise in certain pathovars and even clones...

journal_title：Critical reviews in microbiology

authors： Rossi E,Cimdins A,Lüthje P,Brauner A,Sjöling Å,Landini P,Römling U

更新日期：2018-02-01 00:00:00

abstract：:The agriculture industry is in need of novel biopesticides and development of large-scale production of mycopesticide, either fungal cells themselves or cell-free fungal components. The identification of a fungal strain with pesticide activity, and its improvement, is the primary step in developing infective propagule...

journal_title：Critical reviews in microbiology

authors： Deshpande MV

更新日期：1999-01-01 00:00:00

abstract：:The cyanobacteria (blue-green algae) are photosynthetic prokaryotes having applications in human health with numerous biological activities and as a dietary supplement. It is used as a food supplement because of its richness in nutrients and digestibility. Many cyanobacteria (Microcystis sp, Anabaena sp, Nostoc sp, Os...

journal_title：Critical reviews in microbiology

authors： Raja R,Hemaiswarya S,Ganesan V,Carvalho IS

更新日期：2016-05-01 00:00:00

abstract：:The use of marine microorganisms as potential biofactories for green synthesis of metallic nanoparticles is a relatively new field of research with considerable prospects. This method is eco-friendly, time saving, and inexpensive and can be easily scaled up for large-scale synthesis. The increasing need to develop sim...

journal_title：Critical reviews in microbiology

authors： Manivasagan P,Nam SY,Oh J

更新日期：2016-11-01 00:00:00

abstract：:Toxin-antitoxin (TA) systems consist of a bicistronic operon, encoding a toxin and an antitoxin. They are widely distributed in the prokaryotic kingdom, often in multiple numbers. TAs are implicated in contradicting phenomena of persistence and programmed cell death (PCD) in bacteria. mazEF TA system, one of the widel...

journal_title：Critical reviews in microbiology

authors： Ramisetty BC,Natarajan B,Santhosh RS

更新日期：2015-02-01 00:00:00

abstract：:Riboflavin derivatives are essential cofactors for a myriad of flavoproteins. In bacteria, flavins importance extends beyond their role as intracellular protein cofactors, as secreted flavins are a key metabolite in a variety of physiological processes. Bacteria obtain riboflavin through the endogenous riboflavin bios...

journal_title：Critical reviews in microbiology

authors： García-Angulo VA

更新日期：2017-03-01 00:00:00

abstract：:Programmed cell death (PCD), also referred to as apoptosis, is a cellular "suicide" mechanism, based on information from its own internal metabolism, environment, developmental history, and genome. This system was described in eukaryotes continuously along evolution, through amoebae, nematodes, insects, and animals. P...

journal_title：Critical reviews in microbiology

authors： Hochman A

更新日期：1997-01-01 00:00:00

abstract：:The first Alicyclobacillus spp. was isolated in 1982, and was originally thought to be strictly limited to thermophilic and acidic environments. Two years later, another Alicyclobacillus sp., A. acidoterrestris, was identified as the causative agent in spoilage of commercially pasteurized apple juice. Subsequent studi...

journal_title：Critical reviews in microbiology

authors： Chang SS,Kang DH

更新日期：2004-01-01 00:00:00

abstract：:The brucellae are α-Proteobacteria causing brucellosis, an important zoonosis. Although multiplying in endoplasmic reticulum-derived vacuoles, they cause no cell death, suggesting subtle but efficient use of host resources. Brucellae are amino-acid prototrophs able to grow with ammonium or use glutamate as the sole ca...

journal_title：Critical reviews in microbiology

authors： Ronneau S,Moussa S,Barbier T,Conde-Álvarez R,Zuniga-Ripa A,Moriyon I,Letesson JJ

更新日期：2016-08-01 00:00:00

abstract：:Escherichia coli enterotoxigenic strains produce one or more toxins which action result in production of diarrhea in animals including Man. One of these toxins, STb, has been mainly associated with colibacillosis in swine. Although highly prevalent in pigs with diarrhea, a relation between STb and disease was arduous ...

journal_title：Critical reviews in microbiology

authors： Dubreuil JD

更新日期：2010-08-01 00:00:00

abstract：:The increasing emergence of antimicrobial multiresistant bacteria is of great concern to public health. While these bacteria are becoming an ever more prominent cause of nosocomial and community-acquired infections worldwide, the antibiotic discovery pipeline has been stalled in the last few years with very few effort...

journal_title：Critical reviews in microbiology

authors： Cardona ST,Selin C,Gislason AS

更新日期：2015-01-01 00:00:00

abstract：:The environmental health-related relevance of cyanobacteria is primarily related to their ability to produce a wide range of toxins, which are known to be hazardous to many organisms, including human beings. The occurrence of cyanobacterial blooms has been related to eutrophic surface water. In the bloom-forming proce...

journal_title：Critical reviews in microbiology

authors： Baptista MS,Vasconcelos MT

更新日期：2006-01-01 00:00:00

abstract：:Antibiotic resistance in Gram-negative pathogens has emerged and constituted a global crisis, thereby novel antibiotics and other anti-infective strategies are urgently needed. However, the growing gap between clinical need and drug innovation, coupled with the membrane permeability barrier in Gram-negative bacteria r...

journal_title：Critical reviews in microbiology

authors： Liu Y,Li R,Xiao X,Wang Z

更新日期：2019-05-01 00:00:00

abstract：:Re-emergence of resistance in different pathogens including viruses are the major cause of human disease and death, which is posing a serious challenge to the medical, pharmaceutical and biotechnological sectors. Though many efforts have been made to develop drug and vaccines against re-emerging viruses, researchers a...

journal_title：Critical reviews in microbiology

authors： Rai M,Deshmukh SD,Ingle AP,Gupta IR,Galdiero M,Galdiero S

更新日期：2016-01-01 00:00:00

abstract：:A chronically weak area in research papers, reports, and reviews is the complete identification of important background reference documents that formed the building blocks for the research. A method for systematically determining these important references is presented. Citation-Assisted Background (CAB) is based on t...

journal_title：Critical reviews in microbiology

authors： Kostoff RN

更新日期：2010-11-01 00:00:00

abstract：:Dermatophytoses are superficial infections caused by a group of fungi, the dermatophytes, which invade keratinized tissue of skin, hair, and nails in humans and animals. The importance of normal immune function in resistance to dermatophytoses is substantiated by an increased susceptibility to chronic infection seen i...

journal_title：Critical reviews in microbiology

authors： Calderon RA

更新日期：1989-01-01 00:00:00

abstract：:In terms of genetically determined susceptibility to the clinical antifungal agent 5-fluorocytosine (5-FC), Candida albicans may be homozygous sensitive (FCY/FCY), homozygous resistant (fcy/fcy), or heterozygous (fcy/FCY). Although heterozygotes are only slightly resistant, they occur at significant frequency among cl...

journal_title：Critical reviews in microbiology

authors： Whelan WL

更新日期：1987-01-01 00:00:00

abstract：:Emerging infectious diseases remain among the leading causes of global mortality. Traditional laboratory diagnostic approaches designed to detect and track infectious disease agents provide a framework for surveillance of bio threats. However, surveillance and outbreak investigations using such time-consuming approach...

journal_title：Critical reviews in microbiology

authors： Bokhari H

更新日期：2018-08-01 00:00:00

abstract：:Urease activity is a physiological function of many bacteria that enables these organisms to utilize urea as a source of nitrogen. The association of ureolytic bacteria with human or animal hosts varies widely from a commensal relationship as demonstrated with skin microflora, a symbiotic relationship in the gastroint...

journal_title：Critical reviews in microbiology

authors： McLean RJ,Nickel JC,Cheng KJ,Costerton JW

更新日期：1988-01-01 00:00:00

abstract：:There is an increasing interest in non-albicans Candida species because of the increasing number of fungal infections they cause. Most of these infections can be found in immunocompromised individuals, especially in those infected with human immunodeficiency virus (HIV). Candida dubliniensis is a recently identified y...

journal_title：Critical reviews in microbiology

authors： Schorling SR,Kortinga HC,Froschb M,Mühlschlegel FA

更新日期：2000-01-01 00:00:00

abstract：:The ability of serum complement to kill bacteria has been linked to host resistance to Gram-negative bacteria. A mechanism for killing extracellular organisms during early invasion, following release from infected phagocytic cells, or during bacteremia would contribute to a host's ability to resist disease. In fact, t...

journal_title：Critical reviews in microbiology

authors： Hoffmann EM,Houle JJ

更新日期：1995-01-01 00:00:00

abstract：:Bacterial populations that are exposed to rapidly changing and sometimes hostile environments constantly switch between growth, survival, and death. Understanding bacterial survival and death are therefore cornerstones in a full comprehension of microbial life. During the last few years, new insights have emerged rega...

journal_title：Critical reviews in microbiology

authors： Aertsen A,Michiels CW

更新日期：2004-01-01 00:00:00

abstract：:Biofilms are complex microbial architectures that encase microbial cells in a matrix comprising self-produced extracellular polymeric substances. Microorganisms living in biofilms are much more resistant to hostile environments than their planktonic counterparts and exhibit enhanced resistance against the microbicides...

journal_title：Critical reviews in microbiology

authors： Yin W,Xu S,Wang Y,Zhang Y,Chou SH,Galperin MY,He J

更新日期：2020-12-28 00:00:00

abstract：:Gonorrhea is a major, global public health problem for which there is no vaccine. The continuing emergence of antibiotic-resistant strains raises concerns that untreatable Neisseria gonorrhoeae may become widespread in the near future. Consequently, there is an urgent need for increased efforts towards the development...

journal_title：Critical reviews in microbiology

authors： Edwards JL,Jennings MP,Apicella MA,Seib KL

更新日期：2016-11-01 00:00:00