Binding of cellulose binding modules reveal differences between cellulose substrates.

abstract：:To examine associations between cognitive function and ophthalmological parameters, the population-based Beijing Eye Study examined ophthalmologically and physically 3127 individuals (mean age: 64.2 ± 9.8 years). Using the mini-mental state examination, cognitive function was assessed as cognitive function score (CFS)...

journal_title：Scientific reports

authors： Jonas JB,Wei WB,Zhu LP,Xu L,Wang YX

更新日期：2018-03-19 00:00:00

abstract：:Globally breast cancer is the leading cause of cancer death among women. The breast consists of epithelium, stroma and a mucosal immune system that make up a complex microenvironment. Growing awareness of the role of microbes in the microenvironment recently has led to a series of findings important for human health. ...

journal_title：Scientific reports

authors： Hieken TJ,Chen J,Hoskin TL,Walther-Antonio M,Johnson S,Ramaker S,Xiao J,Radisky DC,Knutson KL,Kalari KR,Yao JZ,Baddour LM,Chia N,Degnim AC

更新日期：2016-08-03 00:00:00

abstract：:The current theories of antimalarial mechanism of artemisinin are inadequate to fully explain the observed effects. In our study, "organism-like" formation of Schistosoma hemozoin granules by attaching to and utilizing erythrocytes to form new ones was observed. This indicates that heme iron is transferred from erythr...

journal_title：Scientific reports

authors： Sun J,Li C,Wang S

更新日期：2016-10-03 00:00:00

abstract：:Topical anesthetics are widely applied in order to relieve the discomfort and anxiety caused by needle insertion and other painful superficial interventions at the oral cavity. So far, there are no commercially available effective topical anesthetic formulations for that purpose, and the most of developments are relat...

journal_title：Scientific reports

authors： Ribeiro LNM,Franz-Montan M,Alcântara ACS,Breitkreitz MC,Castro SR,Guilherme VA,Muniz BV,Rodrigues da Silva GH,de Paula E

更新日期：2020-07-09 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Ravaioli M,De Pace V,Angeletti A,Comai G,Vasuri F,Baldassarre M,Maroni L,Odaldi F,Fallani G,Caraceni P,Germinario G,Donadei C,Malvi D,Del Gaudio M,Bertuzzo VR,Siniscalchi A,Ranieri VM,D'Errico A,Pasquinelli G,Morell

更新日期：2020-09-01 00:00:00

abstract：:'Big data' in healthcare encompass measurements collated from multiple sources with various degrees of data quality. These data require quality control assessment to optimise quality for clinical management and for robust large-scale data analysis in healthcare research. Height and weight data represent one of the mos...

journal_title：Scientific reports

authors： Phan HTT,Borca F,Cable D,Batchelor J,Davies JH,Ennis S

更新日期：2020-06-23 00:00:00

abstract：:The focus of this study is to evaluate the efficacy of Machine Learning (ML) algorithms in the long-lead prediction of El Niño (La Niña) Modoki (ENSO Modoki) index (EMI). We evaluated two widely used non-linear ML algorithms namely Support Vector Regression (SVR) and Random Forest (RF) to forecast the EMI at various l...

journal_title：Scientific reports

authors： Pal M,Maity R,Ratnam JV,Nonaka M,Behera SK

更新日期：2020-01-15 00:00:00

abstract：:The gene separation anxiety (san) encodes Naa50/San, a N-terminal acetyltransferase required for chromosome segregation during mitosis. Although highly conserved among higher eukaryotes, the mitotic function of this enzyme is still poorly understood. Naa50/San was originally proposed to be required for centromeric sis...

journal_title：Scientific reports

authors： Ribeiro AL,Silva RD,Foyn H,Tiago MN,Rathore OS,Arnesen T,Martinho RG

更新日期：2016-12-20 00:00:00

abstract：:Sphingobium sp. strain TCM1 can degrade tris(2-chloroethyl) phosphate (TCEP) to inorganic phosphate and 2-chloroethanol. A phosphotriesterase (PTE), phosphodiesterase (PDE) and phosphomonoesterase (PME) are believed to be involved in the degradation of TCEP. The PTE and PME that respectively catalyze the first and thi...

journal_title：Scientific reports

authors： Abe K,Mukai N,Morooka Y,Makino T,Oshima K,Takahashi S,Kera Y

更新日期：2017-06-06 00:00:00

abstract：:When and where animals breed can shape the genetic structure and diversity of animal populations. The importance of drivers of genetic diversity is amplified in island populations that tend to have more delineated gene pools compared to continental populations. Studies of relatedness as a function of the spatial distr...

journal_title：Scientific reports

authors： Garrett LJH,Myatt JP,Sadler JP,Dawson DA,Hipperson H,Colbourne JK,Dickey RC,Weber SB,Reynolds SJ

更新日期：2020-11-26 00:00:00

abstract：:The current study was conducted to assess the effects of microinjection of different dosages of guide RNA (gRNA)/Cas9 protein on the mutation rate, embryo survival, embryonic development, hatchability and early fry survival in channel catfish, Ictalurus punctatus. Guide RNAs targeting two of the channel catfish immune...

journal_title：Scientific reports

authors： Elaswad A,Khalil K,Ye Z,Liu Z,Liu S,Peatman E,Odin R,Vo K,Drescher D,Gosh K,Qin G,Bugg W,Backenstose N,Dunham R

更新日期：2018-11-07 00:00:00

abstract：:Osteochondral defects contain damage to both the articular cartilage and underlying subchon- dral bone, which remains a significant challenge in orthopedic surgery. Layered structure of bone, cartilage and the bone-cartilage interface must be taken into account in the case of biofabrication of the osteochondral (OC) i...

journal_title：Scientific reports

authors： Ayan B,Wu Y,Karuppagounder V,Kamal F,Ozbolat IT

更新日期：2020-08-04 00:00:00

abstract：:Exposure to silica can cause lung fibrosis and cancer. Identification of molecular targets is important for the intervention and/or prevention of silica-induced lung diseases. Telomeres consist of tandem repeats of DNA sequences at the end of chromosomes, preventing chromosomal fusion and degradation. Regulator of tel...

journal_title：Scientific reports

authors： Shoeb M,Joseph P,Kodali V,Mustafa G,Farris BY,Umbright C,Roberts JR,Erdely A,Antonini JM

更新日期：2017-12-11 00:00:00

abstract：:NOTCH plays a pivotal role during normal development and in congenital disorders and cancer. γ-secretase inhibitors are commonly used to probe NOTCH function, but also block processing of numerous other proteins. We discovered a new class of small molecule inhibitor that disrupts the interaction between NOTCH and RBPJ...

journal_title：Scientific reports

authors： Hurtado C,Safarova A,Smith M,Chung R,Bruyneel AAN,Gomez-Galeno J,Oswald F,Larson CJ,Cashman JR,Ruiz-Lozano P,Janiak P,Suzuki T,Mercola M

更新日期：2019-07-25 00:00:00

abstract：:Potential of microalgal cultivation as an alternative approach to the treatment of anaerobic digestion (AD) effluents was examined using two representative Chlorella species, Chlorella vulgaris (CV) and Chlorella protothecoides (CP). Both species effectively removed NH4+-N from the AD effluents from four digesters tre...

journal_title：Scientific reports

authors： Yu H,Kim J,Lee C

更新日期：2019-04-16 00:00:00

abstract：:Huanglongbing (HLB) (citrus greening disease) is one of the most serious bacterial diseases of citrus. It is caused by (1) Candidatus Liberibacter africanus, transmitted by Trioza erytreae and (2) C.L. asiaticus and C.L. americanus, transmitted by Diaphorina citri. As part of a multidisciplinary project on D. citri (w...

journal_title：Scientific reports

authors： Alba-Alejandre I,Alba-Tercedor J,Hunter WB

更新日期：2020-04-28 00:00:00

abstract：:Ultrasound imaging is affected by coherent noise or speckle, which reduces contrast and overall image quality and degrades the diagnostic precision of the collected images. Elevational angular compounding (EAC) is an attractive means of addressing this limitation, since it reduces speckle noise while operating in real...

journal_title：Scientific reports

authors： Afshari P,Zakian C,Ntziachristos V

更新日期：2020-10-23 00:00:00

abstract：:Difficulties in the production of lignin from rice straw because of high silica content in the recovered lignin reduce its recovery yield and applications as bio-fuel and aromatic chemicals. Therefore, the objective of this study is to develop a novel method to reduce the silica content in lignin from rice straw more ...

journal_title：Scientific reports

authors： Do NH,Pham HH,Le TM,Lauwaert J,Diels L,Verberckmoes A,Do NHN,Tran VT,Le PK

更新日期：2020-12-04 00:00:00

abstract：:Cellular clearance mechanisms including the autophagy-lysosome pathway are impaired in amyotrophic lateral sclerosis (ALS). One of the most important proteins involved in the regulation of autophagy is the lysosomal Ca2+ channel Mucolipin TRP channel 1 (TRPML1). Therefore, we investigated the role of TRPML1 in a neuro...

journal_title：Scientific reports

authors： Tedeschi V,Petrozziello T,Sisalli MJ,Boscia F,Canzoniero LMT,Secondo A

更新日期：2019-07-24 00:00:00

abstract：:We have investigated the rotating magnetocaloric effect (R-MCE) of TmB4 - an anisotropic magnetic system with geometrical frustration of Shastry-Sutherland type. The R-MCE was obtained from detailed temperature dependencies of heat capacity in various magnetic fields of a single crystalline sample for crystal axes ori...

journal_title：Scientific reports

authors： Orendáč M,Gabáni S,Gažo E,Pristáš G,Shitsevalova N,Siemensmeyer K,Flachbart K

更新日期：2018-07-19 00:00:00

abstract：:Osteoporosis medication in fragility fracture patients is associated with better outcomes. However, limited studies have investigated whether fracture types affect outcomes among patients undergoing treatment. We performed a secondary data analysis on participants from a fracture liaison service and an osteoporosis me...

journal_title：Scientific reports

authors： Chang CB,Yang RS,Chang LY,Peng JK,Tsai KS,Huang WJ,Yang TH,Chan DC

更新日期：2019-07-12 00:00:00

abstract：:To investigate changes in the size of the population of patients who are receiving long-term, active treatment for neovascular age-related macular degeneration (AMD). This retrospective, observational study included 18,165 patients who received anti-vascular endothelial growth factor injections (3,974 eyes). The injec...

journal_title：Scientific reports

authors： Baek SK,Kim JH,Kim JW,Kim CG

更新日期：2019-09-13 00:00:00

abstract：:The p53 protein is a key mediator of the cellular response to various stress signals. In response to DNA damage, the concentration of p53 can temporally oscillate with fluctuations in both the amplitude and period. The underlying mechanism for p53 variability is not fully understood. Here, we construct a core regulato...

journal_title：Scientific reports

authors： Wang DG,Wang S,Huang B,Liu F

更新日期：2019-04-10 00:00:00

abstract：:Circulating levels of Brain Derived Neurotrophic Factor (BDNF) are lower in coronary heart disease (CHD) than in healthy subjects and are associated with coronary events and mortality. However, the mechanism(s) underling this association is not fully understood. We hypothesize that BDNF may influence fibrin fiber stru...

journal_title：Scientific reports

authors： Amadio P,Porro B,Sandrini L,Fiorelli S,Bonomi A,Cavalca V,Brambilla M,Camera M,Veglia F,Tremoli E,Barbieri SS

更新日期：2019-01-23 00:00:00

abstract：:The response of olfactory receptor neurons to odor mixtures is not well understood. Here, using experimental constraints, we investigate the mathematical structure of the odor response space and its consequences. The analysis suggests that the odor response space is 3-dimensional, and predicts that the dose-response c...

journal_title：Scientific reports

authors： Marasco A,De Paris A,Migliore M

更新日期：2016-04-07 00:00:00

abstract：:The end-Triassic is characterized by one of the largest mass extinctions in the Phanerozoic, coinciding with major carbon cycle perturbations and global warming. It has been suggested that the environmental crisis is linked to widespread sill intrusions during magmatism associated with the Central Atlantic Magmatic Pr...

journal_title：Scientific reports

authors： Heimdal TH,Svensen HH,Ramezani J,Iyer K,Pereira E,Rodrigues R,Jones MT,Callegaro S

更新日期：2018-01-09 00:00:00

abstract：:DNA-based data storage has emerged as a promising method to satisfy the exponentially increasing demand for information storage. However, practical implementation of DNA-based data storage remains a challenge because of the high cost of data writing through DNA synthesis. Here, we propose the use of degenerate bases a...

journal_title：Scientific reports

authors： Choi Y,Ryu T,Lee AC,Choi H,Lee H,Park J,Song SH,Kim S,Kim H,Park W,Kwon S

更新日期：2019-04-29 00:00:00

abstract：:Elevated ground-level ozone (O3), which is an important aspect of air quality related to public health, has been causing increasing concern. This study investigated the spatiotemporal distribution of ground-level O3 concentrations in China using a dataset from the Chinese national air quality monitoring network during...

journal_title：Scientific reports

authors： Wang WN,Cheng TH,Gu XF,Chen H,Guo H,Wang Y,Bao FW,Shi SY,Xu BR,Zuo X,Meng C,Zhang XC

更新日期：2017-06-16 00:00:00

abstract：:Superior cervical ganglion neurons (SCGN) are often used to investigate neurotransmitter release mechanisms. In this study, we optimized the dissociation and culture conditions of rat SCGN cultures for dual patch clamp recordings. Two weeks in vitro are sufficient to achieve a significant CNTF-induced cholinergic swit...

journal_title：Scientific reports

authors： Amendola J,Boumedine N,Sangiardi M,El Far O

更新日期：2015-09-24 00:00:00

abstract：:Preventing the protein-protein interaction of the cellular chromatin binding protein Lens Epithelium-Derived Growth Factor (LEDGF) and human immunodeficiency virus (HIV) integrase is an important possible strategy for anti-viral treatment for AIDS. We have used Intracellular Antibody Capture technology to isolate a si...

journal_title：Scientific reports

authors： Bao L,Hannon C,Cruz-Mignoni A,Ptchelkine D,Sun MY,Miller A,Bunjobpol W,Quevedo CE,Derveni M,Chambers J,Simmons A,Phillips SEV,Rabbitts TH

更新日期：2017-12-04 00:00:00