Abstract：
PURPOSE:To evaluate the clinical course after early surgical treatment with excision of retinal hemangioblastomas (RHs) before development of major complications. METHODS:Interventional case series of four eyes (four patients) with a peripheral RH that had not yet been treated by laser or cryotherapy prior to surgery. All eyes underwent 23-gauge vitrectomy with lesion excision. One patient underwent ligation of the feeder vessel prior to lesion excision. Best-corrected visual acuity and clinical course were assessed during a follow-up period of at least 4 years. RESULTS:Four patients (mean age 27.3 years; range 19-32) were included, of whom two had von Hippel-Lindau syndrome. Visual acuity improved in three patients (mean 4.8 lines; range 3-10) and remained stable at 0.0 logMAR in one patient. There were no intraoperative complications. Postoperative complications included transient mild vitreous haemorrhage (n = 2), and local epiretinal membrane formation at the excision location (n = 1). At 4 years postoperatively, there were no long-term complications. There was one case of a new lesion, which was effectively treated with laser. CONCLUSION:Vitrectomy with RH excision seems to be an effective approach for larger RHs and could be considered an early treatment option in selected cases. Postoperative complications were limited in scope of this case series. Important points to consider during vitrectomy are effective closure of feeder and draining vessels as well as complete removal of posterior hyaloid and epiretinal membranes in order to avoid postoperative vitreous haemorrhage and proliferative vitreoretinopathy.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
van Overdam KA,Missotten T,Kilic E,Spielberg LHdoi
10.1111/aos.13223subject
Has Abstractpub_date
2017-02-01 00:00:00pages
97-102issue
1eissn
1755-375Xissn
1755-3768journal_volume
95pub_type
abstract：PURPOSE:We aimed to assess the macular anatomy using spectral domain optical coherence tomography (SD-OCT), in children born preterm who had laser-treated retinopathy of prematurity (ROP), and to investigate the relationship between structural changes in macula and visual function. METHODS:Thirty-seven 3-8 years old c...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.13536
更新日期：2018-03-01 00:00:00
abstract：PURPOSE:To evaluate intraocular pressure (IOP) control over 24 hours using travoprost and timolol fixed combination (TTFC) administered in the morning or evening in primary open-angle and exfoliative glaucoma. METHODS:Patients were randomized to TTFC administered in either the morning or evening for 8 weeks. Previousl...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1755-3768.2007.01145.x
更新日期：2009-02-01 00:00:00
abstract：:This literature review is aimed at the evaluation of the potential for cataract prevention in Europe. It was performed using PubMed with Mesh and free-text terms. Studies included were (i) performed on a population of Caucasian origin at an age range of 40-95 years, (ii) cataract was clinically verified, (iii) drug re...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,评审
doi：10.1111/j.1755-3768.2012.02444.x
更新日期：2013-08-01 00:00:00
abstract：PURPOSE:To determine the molecular genetic cause in previously unreported probands with optic atrophy from the United Kingdom, Czech Republic and Canada. METHODS:OPA1 coding regions and flanking intronic sequences were screened by direct sequencing in 82 probands referred with a diagnosis of bilateral optic atrophy. D...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.13285
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:To compare the outcomes of microcatheter-assisted circumferential trabeculotomy to standard rigid probe trabeculotomy in childhood glaucomas. METHODS:Eyes of children requiring trabeculotomy for primary congenital or secondary paediatric glaucoma were randomized to undergo either trabeculotomy using the Glauco...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,随机对照试验
doi：10.1111/aos.13414
更新日期：2017-12-01 00:00:00
abstract：PURPOSE:To estimate the prevalence of primary angle-closure glaucoma (PACG), primary angle closure (PAC) and primary angle-closure suspect (PACS) and associated risk factors for PACG in a rural population in Northeast China. METHODS:A population-based survey was conducted in Bin County, Harbin, Northeast China. Glauco...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2011.02146.x
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:To compare the effectiveness of intravitreal conbercept and ranibizumab treatment for retinopathy of prematurity (ROP). METHODS:In this retrospective study, the date of patients with ROP treated with intravitreal conbercept or ranibizumab from July 2012 to March 2018 with at least 12 months of follow-up at the...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14460
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:Eyelid sebaceous carcinoma (SC) remains a common diagnostic pitfall for both the clinician and histopathologist. The aim of this study was to describe perforin as a new marker in the immunohistochemistry panel for SC. METHODS:A total of 29 cases were retrieved from the Pathology archives, including 11 sebaceou...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.12972
更新日期：2016-08-01 00:00:00
abstract：PURPOSE:We investigated the natural course of the intraretinal hyperreflective (IRH) sign after macular haemorrhage (MHE) absorption in eyes with pathologic myopia. METHODS:This prospective observational cohort study evaluated 28 patients with pathologic myopia and MHE. The eyes were categorized into IRH and non-IRH s...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14332
更新日期：2019-12-06 00:00:00
abstract：PURPOSE:To compare visual acuity (VA) change at 24 months in eyes with clinically significant DME (CSDME) and good VA initially treated versus initially observed in routine clinical practice. METHODS:Retrospective analysis of treatment-naïve eyes with CSDME and good VA (baseline VA ≥ 79 letters), with at least 24 mont...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14672
更新日期：2020-11-16 00:00:00
abstract：:There is still no agreement on total plasma homocysteine (tHcy) role in age-related macular degeneration (AMD), the leading cause of new blindness in industrialized countries. We performed a systematic review and meta-analysis of the published data on the correlation between tHcy and AMD. MEDLINE/PubMed and ISI Web of...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,meta分析,评审
doi：10.1111/aos.13343
更新日期：2018-05-01 00:00:00
abstract：PURPOSE:The introduction of vascular endothelial growth factor inhibitors for the treatment of exudative age-related macular degeneration (AMD) has increased the referral rates of AMD patients with visual symptoms to treating centres considerably. However, a large proportion of the referred patients do not qualify for ...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2010.02074.x
更新日期：2012-08-01 00:00:00
abstract：PURPOSE:Angiogenic inhibitors, alone or combined with other therapies, are believed to represent a promising treatment for neovascularization in age-related macular degeneration (wet AMD). They can maintain or improve visual acuity (VA), at least for the first 2years. However, evolution to retinal atrophy cannot be rul...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2009.01526.x
更新日期：2010-09-01 00:00:00
abstract：PURPOSE:To evaluate the impact of pseudoexfoliation syndrome on intraocular lens (IOL) dislocation after phacoemulsification cataract surgery and explore possible associations related to surgical technique. METHODS:We systematically searched the MEDLINE, Embase, Web of Science, Cochrane, and Lilacs databases and grey ...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,meta分析,评审
doi：10.1111/aos.13234
更新日期：2017-05-01 00:00:00
abstract：PURPOSE:Retinal pigment epithelium (RPE) tear is an extremely rare complication in patients with classic neovascular membranes without RPE detachment. We evaluate their incidence and functional outcome following treatment with intravitreal ranibizumab. METHODS:Observational study of 72 consecutive patients (74 eyes) t...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2009.01547.x
更新日期：2010-11-01 00:00:00
abstract：PURPOSE:Photoscreening assesses risk factors for amblyopia, as an alternative to measurement of visual acuity (VA) to detect amblyopia, on the premise that its early correction could prevent development of amblyopia. We studied implementations of Plusoptix photoscreening in existing population-based screening in Flande...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,评审
doi：10.1111/aos.14144
更新日期：2020-02-01 00:00:00
abstract：:Asteroid hyalosis is defined by the presence of white, snowball-like non-crystalline vitreous opacities that move with the vitreous and appear to be anchored to its matrix. Asteroid hyalosis commonly occurs in the absence of other identifiable ocular abnormalities and is usually an incidental finding. The vitreous opa...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,评审
doi：10.1111/aos.14465
更新日期：2020-12-01 00:00:00
abstract：PURPOSE: To evaluate the precision of techniques for measuring intraocular pressure (IOP) in corneas with presumably altered biomechanical properties. METHODS: Intraocular pressure was measured with a Goldmann applanation tonometer (GAT), ocular response analyzer (ORA) and dynamic contour tonometer (DCT) in 70 eyes....
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.12137
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:To evaluate the ability of ultrasound biomicroscopy (UBM) to detect abnormalities in the zonular apparatus in unaffected eyes of patients with clinically unilateral exfoliation syndrome (XFS) using a standardized grading system. METHODS:The affected and unaffected eyes of 17 patients with clinically unilateral...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1600-0420.2007.01105.x
更新日期：2008-08-01 00:00:00
abstract：PURPOSE:To assess the condition of the corneal endothelium an extended period after cataract surgery in eyes with and without pseudoexfoliation syndrome (PES). METHODS:Forty-six patients with PES who underwent cataract surgery in the Eye Department, Oslo University Hospital, in 2001 and 2002 were enrolled and compared...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2010.02012.x
更新日期：2012-08-01 00:00:00
abstract：PURPOSE:Our purpose was to evaluate the surgical outcome after intra-ocular lens exchange in patients who presented impairing visual complaints after primary multifocal intra-ocular lens (MIOL) implantation. In particular, the study was undertaken to look at the number of eyes that could be equipped with the bag-in-the...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.12093
更新日期：2014-05-01 00:00:00
abstract：PURPOSE:To evaluate the impact of dynamic exercise on retinal vessel oxygen saturation in healthy individuals. METHODS:Twenty-six healthy participants underwent moderate dynamic exercise (modified Master's two-step exercise). In all subjects, intraocular pressures (IOP), systolic and diastolic blood pressures (SBP and...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.13576
更新日期：2018-05-01 00:00:00
abstract：PURPOSE:To evaluate effectiveness, tolerability and safety of repeated intravitreal injections of 0.5 mg ranibizumab for the treatment of neovascular age-related macular degeneration in routine medical practice in Germany. METHODS:A noninterventional study with 3470 patients treated in 274 medical centres according to...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1755-3768.2012.02493.x
更新日期：2013-09-01 00:00:00
abstract：PURPOSE:To report the functional and anatomical outcomes resulting from the use of intravitreal pegaptanib sodium (Macugen) in patients with diabetic macular oedema (DMO). METHODS:We conducted a retrospective outcome analysis, by optical coherence tomography (OCT) and best-corrected visual acuity (BCVA), of eyes with ...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2009.01580.x
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:To evaluate the effect of photodynamic therapy (PDT) on central serous chorioretinopathy (CSC) compared with laser therapy and intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) drugs, and to find the maximum treatment effect with minimal dose and fluence of PDT. METHODS:A systematic...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,meta分析,评审
doi：10.1111/aos.12482
更新日期：2014-12-01 00:00:00
abstract：PURPOSE:To explore associations of lamina cribrosa thickness with axial length and thickness of the posterior sclera in monkeys. METHODS:Examining histological sections by light microscopy, we measured the thickness of the lamina cribrosa and posterior sclera and axial length. RESULTS:The study included 28 animals (2...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.13070
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:To describe the retinal structure of a group of patients affected by methylmalonic aciduria with homocystinuria cblC type, caused by mutations in the MMACHC gene, using spectral domain optical coherence tomography (SD-OCT). METHODS:Young patients (n = 11, age 0-74 months) with cblC disease, detected by newborn...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,多中心研究
doi：10.1111/aos.13441
更新日期：2017-12-01 00:00:00
abstract：PURPOSE:To investigate the utility of biomechanical property measurements using a Scheimpflug-based tonometer (SBT) and/or anterior segment optical coherence tomography (AS-OCT) for diagnosing forme fruste keratoconus (FFK). METHODS:In this retrospective interventional case series, 23 eyes with FFK of 23 consecutive p...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14700
更新日期：2020-12-16 00:00:00
abstract：PURPOSE:Orally administered angiotensin II receptor blockers (ARBs) decrease intraocular pressure (IOP). Topical administration may reduce systemic side effects and result in a useful glaucoma drug. The aim of this study is to test the ocular delivery and pharmacologic effect of nanoparticle eye drops containing ARBs (...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14639
更新日期：2020-11-16 00:00:00
abstract：PURPOSE:To describe three cases of Charles Bonnet syndrome (CBS) in glaucoma patients with preserved visual acuity. METHODS:Three glaucoma patients who had taken part in a recent CBS study were interviewed about their hallucinations. The patients underwent macular optical coherence tomography (OCT) of both eyes. The v...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14620
更新日期：2020-09-11 00:00:00
