Abstract:
:In bulk superfluid 3He at zero magnetic field, two phases emerge with the B-phase stable everywhere except at high pressures and temperatures, where the A-phase is favoured. Aerogels with nanostructure smaller than the superfluid coherence length are the only means to introduce disorder into the superfluid. Here we use a torsion pendulum to study 3He confined in an extremely anisotropic, nematically ordered aerogel consisting of ∼10 nm-thick alumina strands, spaced by ∼100 nm, and aligned parallel to the pendulum axis. Kinks in the development of the superfluid fraction (at various pressures) as the temperature is varied correspond to phase transitions. Two such transitions are seen in the superfluid state, and we identify the superfluid phase closest to Tc at low pressure as the polar state, a phase that is not seen in bulk 3He.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Zhelev N,Reichl M,Abhilash TS,Smith EN,Nguyen KX,Mueller EJ,Parpia JMdoi
10.1038/ncomms12975subject
Has Abstractpub_date
2016-09-27 00:00:00pages
12975issn
2041-1723pii
ncomms12975journal_volume
7pub_type
杂志文章abstract::Adoptive immunotherapy using chimeric antigen receptor (CAR) expressing T cells targeting the CD19 B lineage receptor has demonstrated marked success in relapsed pre-B-cell acute lymphoblastic leukaemia (ALL). Persisting CAR-T cells generate sustained pressure against CD19 that may drive unique mechanisms of resistanc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12320
更新日期:2016-07-27 00:00:00
abstract::Functional blood vessel growth depends on generation of distinct but coordinated responses from endothelial cells. Bone morphogenetic proteins (BMP), part of the TGFβ superfamily, bind receptors to induce phosphorylation and nuclear translocation of SMAD transcription factors (R-SMAD1/5/8) and regulate vessel growth. ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13247
更新日期:2016-11-11 00:00:00
abstract::Overexpression of a drug's molecular target often increases drug resistance, offering a pathway for adaptive evolution and a tool for target identification. It is unclear though why this phenomenon applies to some drugs but not others. Here we gradually overexpressed antibiotic targets in Escherichia coli and found th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5296
更新日期:2014-07-01 00:00:00
abstract::Photothermal heating represents a major constraint that limits the performance of many nanoscale optoelectronic and optomechanical devices including nanolasers, quantum optomechanical resonators, and integrated photonic circuits. Here, we demonstrate the direct laser refrigeration of a semiconductor optomechanical res...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16472-6
更新日期:2020-06-23 00:00:00
abstract::Increasing evidence suggests that neural population responses have their own internal drive, or dynamics, that describe how the neural population evolves through time. An important prediction of neural dynamical models is that previously observed neural activity is informative of noisy yet-to-be-observed activity on s...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8759
更新日期:2015-07-29 00:00:00
abstract::Identifying regions important for spreading and mediating perturbations is crucial to assess the susceptibilities of spatio-temporal complex systems such as the Earth's climate to volcanic eruptions, extreme events or geoengineering. Here a data-driven approach is introduced based on a dimension reduction, causal reco...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9502
更新日期:2015-10-07 00:00:00
abstract::Zinc finger E-box binding homeobox 1 (Zeb1) has been demonstrated to participate in the acquisition of the properties of cancer stem cells (CSCs). However, it is largely unknown how signals from the tumor microenvironment (TME) contribute to aberrant Zeb1 expression. Here, we show that Zeb1 depletion suppresses stemne...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18860-4
更新日期:2020-10-12 00:00:00
abstract::This corrects the article DOI: 10.1038/ncomms15317. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/ncomms16128
更新日期:2017-06-30 00:00:00
abstract::Wilms tumor gene on the X chromosome (WTX) is a putative tumor suppressor gene in Wilms tumor, but its expression and functions in other tumors are unclear. Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in women and the second leading cause in men in the United States. We demonstrated tha...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07998-x
更新日期:2019-01-10 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 已发布勘误
doi:10.1038/s41467-019-13138-w
更新日期:2019-11-22 00:00:00
abstract::Epilepsy is a common brain disorder throughout history. Epilepsy-related ligand-receptor complex, LGI1-ADAM22, regulates synaptic transmission and has emerged as a determinant of brain excitability, as their mutations and acquired LGI1 autoantibodies cause epileptic disorders in human. Here, we report the crystal stru...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03947-w
更新日期:2018-04-18 00:00:00
abstract::Starting from the gas phase, small clusters can be produced and deposited with huge flexibility with regard to composition, materials choice and cluster size. Despite many advances in experimental characterization, a detailed morphology of such clusters is still lacking. Here we present an atomic scale observation as ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1887
更新日期:2012-06-12 00:00:00
abstract::The human Immunodeficiency Centromeric Instability Facial Anomalies (ICF) 4 syndrome is a severe disease with increased mortality caused by mutation in the LSH gene. Although LSH belongs to a family of chromatin remodeling proteins, it remains unknown how LSH mediates its function on chromatin in vivo. Here, we use ch...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19159-0
更新日期:2020-11-06 00:00:00
abstract::Non-linear interactions in coherent gases are not only at the origin of bright and dark solitons and superfluids; they also give rise to phenomena such as multistability, which hold great promise for the development of advanced photonic and spintronic devices. In particular, spinor multistability in strongly coupled s...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3008
更新日期:2013-01-01 00:00:00
abstract::Digital polymers with precisely ordered units acting as the coded 0- or 1-bit, are introduced as a promising option for molecular data storage. However, the pursuit of better performance in terms of high storage capacity and useful functions never stops. Herein, we propose a concept of an information-coded 2D digital ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09957-6
更新日期:2019-04-23 00:00:00
abstract::It is difficult to achieve minimally invasive injectable cell delivery while maintaining high cell retention and animal survival for in vivo stem cell therapy of myocardial infarction. Here we show that pluripotent stem cell aggregates pre-differentiated into the early cardiac lineage and encapsulated in a biocompatib...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13306
更新日期:2016-10-27 00:00:00
abstract::Lithium- and sodium-rich layered transition-metal oxides have recently been attracting significant interest because of their large capacity achieved by additional oxygen-redox reactions. However, layered transition-metal oxides exhibit structural degradation such as cation migration, layer exfoliation or cracks upon d...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09409-1
更新日期:2019-05-16 00:00:00
abstract::CD47 is a cell surface molecule that inhibits phagocytosis of cells that express it by binding to its receptor, SIRPα, on macrophages and other immune cells. CD47 is expressed at different levels by neoplastic and normal cells. Here, to reveal mechanisms by which different neoplastic cells generate this dominant 'don'...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14802
更新日期:2017-04-05 00:00:00
abstract::Microalbuminuria is an important clinical marker of several cardiovascular, metabolic, and other diseases such as diabetes, hypertension, atherosclerosis, and cancer. The accurate detection of microalbuminuria relies on albumin quantification in the urine, usually via an immunoturbidity assay; however, like many antib...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11583-1
更新日期:2019-08-09 00:00:00
abstract::Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr Virus (EBV) establish life-long infections and are associated with malignancies. Striking geographic variation in incidence and the fact that virus alone is insufficient to cause disease, suggests other co-factors are involved. Here we present epidemiolog...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17696-2
更新日期:2020-07-31 00:00:00
abstract::Cortical neurons are often functionally heterogeneous even for molecularly defined subtypes. In sensory cortices, physiological responses to natural stimuli can be sparse and vary widely even for neighboring neurons. It is thus difficult to parse out circuits that encode specific stimuli for further experimentation. H...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03183-2
更新日期:2018-02-28 00:00:00
abstract::Epitaxial films may be released from growth substrates and transferred to structurally and chemically incompatible substrates, but epitaxial films of transition metal perovskite oxides have not been transferred to electroactive substrates for voltage control of their myriad functional properties. Here we demonstrate g...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16942-x
更新日期:2020-06-24 00:00:00
abstract::Advances in chemistry and massively parallel detection underlie DNA-sequencing platforms that are poised for application in personalized medicine. In stark contrast, systematic generation of protein-level data lags well behind genomics in virtually every aspect: depth of coverage, throughput, ease of sample preparatio...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3171
更新日期:2013-01-01 00:00:00
abstract::The original HTML version of this Article had an incorrect Published online date of 20 March 2019; it should have been 18 March 2019. This has been corrected in the HTML version of the Article. The PDF version was correct from the time of publication. ...
journal_title:Nature communications
pub_type: 已发布勘误
doi:10.1038/s41467-019-09797-4
更新日期:2019-04-18 00:00:00
abstract::Adult neural stem cells (NSCs) reside in a specialized microenvironment, the subventricular zone (SVZ), which provides them with unique signaling cues to control their basic properties and prevent their exhaustion. While the signaling mechanisms that regulate NSC lineage progression are well characterized, the molecul...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02440-0
更新日期:2018-01-02 00:00:00
abstract::Plasmids are important members of the bacterial mobile gene pool, and are among the most important contributors to horizontal gene transfer between bacteria. They typically harbour a wide spectrum of host beneficial traits, such as antibiotic resistance, inserted into their backbones. Although these inserted elements ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1267
更新日期:2011-01-01 00:00:00
abstract::Capturing and controlling plasmons at buried interfaces with nanometre and femtosecond resolution has yet to be achieved and is critical for next generation plasmonic devices. Here we use light to excite plasmonic interference patterns at a buried metal-dielectric interface in a nanostructured thin film. Plasmons are ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13156
更新日期:2016-10-11 00:00:00
abstract::Cytokines are involved in early host defense against pathogen infections. In particular, tumor necrosis factor (TNF) and interferon-gamma (IFN-γ) have critical functions in non-cytopathic elimination of hepatitis B virus (HBV) in hepatocytes. However, the molecular mechanisms and mediator molecules are largely unknown...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05782-5
更新日期:2018-08-16 00:00:00
abstract::Osteosarcoma is the most frequent primary bone tumor with poor prognosis. Through RNA-sequencing of 100,987 individual cells from 7 primary, 2 recurrent, and 2 lung metastatic osteosarcoma lesions, 11 major cell clusters are identified based on unbiased clustering of gene expression profiles and canonical markers. The...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20059-6
更新日期:2020-12-10 00:00:00
abstract::Diatoms contribute roughly 20% of global primary production, but the factors determining their ability to adapt to global warming are unknown. Here we quantify the capacity for adaptation to warming in the marine diatom Thalassiosira pseudonana. We find that evolutionary rescue under severe (32 °C) warming is slow, bu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03906-5
更新日期:2018-04-30 00:00:00