Abstract:
:In this report, membranes removed during vitrectomy were observed by various methods of electron microscopy to determine their three-dimensional structure and the mechanism of the contraction of preretinal membranes. The vitreous side surface of the preretinal membranes was covered by two types of flat cells, cells with long, extended processes and cells in a pavement arrangement. The lamellae of the flat cells in the internal structures of the preretinal membranes were also observed. In each lamella, the cells appeared to have a connection with each other and formed networks. The retinal side surface of the preretinal membranes was smooth and acellular. The glycerinated preretinal membranes were exposed to ATP and Mg2+, which induced the contraction of the component cells of the preretinal membranes. When the cells on the vitreous side surface of the preretinal membranes contracted, the intercellular connections among them appeared to be preserved.
journal_name
Jpn J Ophthalmoljournal_title
Japanese journal of ophthalmologyauthors
Yamamoto T,Yamashita H,Hori Ssubject
Has Abstractpub_date
1989-01-01 00:00:00pages
151-65issue
2eissn
0021-5155issn
1613-2246journal_volume
33pub_type
杂志文章abstract:PURPOSE:The purpose of this study was to estimate the optimal size of visual field test for detecting longitudinal changes in retinitis pigmentosa (RP) by dividing the visual field. METHODS:We reviewed the results of 10° static visual field tests in 19 eyes of 19 RP patients. Sixty-eight numeric value points were divi...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-013-0235-y
更新日期:2013-05-01 00:00:00
abstract::Single fiber electromyography (SFEMG) was carried out in the extraocular muscles (EOMs) of 40 adult cats, and the recordings were analyzed. The small fluctuations of the interpotential interval (IPI), so-called "jitter phenomenon", were represented quantitatively as a mean consecutive difference (MCD). The MCD and the...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:To verify, by use of data collected by the Japan Glaucoma Society Survey of Bleb-related Infection (JGSSBI), that bleb morphology changes within 12 months of the development of bleb-related infection. METHODS:JGSSBI data from 57 eyes of 57 patients with primary open-angle glaucoma and normal tension glaucoma w...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10384-015-0398-9
更新日期:2015-09-01 00:00:00
abstract::A unilateral intravitreal inoculation of herpes simplex virus type 1 (HSV-1) induced bilateral retinitis and encephalitis in the rat. Immunohistochemistry was employed to clarify the pathway of transmission of HSV-1 from the inoculated eye to the contralateral eye, and to identify localization of the viral antigen in ...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To compare the accuracy of postoperative pachymetry between Orbscan II (Bausch & Lomb) scanning-slit corneal topography/pachymetry and the Pentacam (Oculus) rotating Scheimpflug camera. METHODS:Central corneal thickness (CCT) was determined in 24 patients (48 eyes) before and after laser in situ keratomileusis...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-008-0550-x
更新日期:2008-07-01 00:00:00
abstract::A major and a minor ascorbate free radical (AFR) reductase were separated from the soluble fraction in the human lens cortex by DEAE-cellulose ion-exchange column chromatography. These AFR reductases also exhibited diaphorase activity using dichlorophenolindophenol and ferricyanide as electron acceptors. The major AFR...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:To study the effects of antiglaucoma eye drops on N-methyl-D-aspartate (NMDA)-induced retinal damage. METHODS:Several antiglaucoma eye drops, beta-blockers, alpha/beta-blockers, an alpha1-blocker, an alpha2-agonist, and a prostaglandin derivative, were topically administrated to NMDA-treated rat eyes daily for...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-005-0253-5
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:To determine whether exposure to ozonated solution alters the morphology of corneal endothelial cells in rats and to examine the protective effect of ascorbic acid. METHODS:The anterior chambers of rat eyes were filled with 4 ppm of ozonated solution. Some were left in that state, while others were flushed out...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-008-0629-4
更新日期:2009-03-01 00:00:00
abstract::The clinical and etiological findings in 727 patients with viral conjunctivitis treated from January 1982 through December 1984 at Aoki Eye Clinic in Sapporo, Japan, were presented. The age of the patients ranged from 11 days to 88 years, and the monthly incidences of the disease from 18 to 131 cases, with a clusterin...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::A 25-year-old woman is described whose clinical features included infantile hypotonia, obesity after infancy, intellectual impairment, dysmorphic facial features, short stature, small hands and feet, and abnormal dentition, which are typical of the Prader-Willi syndrome. The patient had almond-shaped eyes, spot-like h...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::The effects of local hypothermia on postoperative inflammation, electroretinogram (ERG) and histological changes of the retina were evaluated in experimental vitrectomy in pressure-induced ischemic rabbit eyes. The solutions used for intraocular perfusion were maintained at 8 degrees C, 22 degrees C or 38 degrees C. F...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Silicone oil was injected into the eyes of 28 rabbits. Utilizing the specific affinity of osmium tetroxide for lipids, the pathological features and histochemical localization of silicone oil within the retina were studied. This osmium tetroxide technique makes it possible to identify the presence of silicone oil part...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::A case of unilateral disc-shaped cataract with coloboma of the lens is reported. The patient, a 17-year-old girl, had best corrected visual acuity of 0.01 (+ 9 D) in the right eye and 1.2 in the left eye. Exotropia of 10 Hirschberg degrees was found in her right eye. The visual disturbance of that eye was thought to b...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::We evaluated the effectiveness of performing a core vitrectomy to prevent intraoperative posterior chamber pressure evaluation in eyes at high risk for development of this complication, prior to penetrating keratoplasty, extracapsular cataract extraction and posterior chamber lens (IOL) implantation. Results in 10 cas...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(97)00046-4
更新日期:1997-07-01 00:00:00
abstract:PURPOSE:To investigate the expression of beta-defensin in the ocular surface of a mouse experimental allergic conjunctivitis (EAC) model. METHODS:Mouse beta-defensin (mBD)-1 and -2 mRNA expressed in conjunctival tissue of both the EAC and the control group were analyzed by real-time reverse transcriptase-polymerase ch...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-005-0262-4
更新日期:2006-01-01 00:00:00
abstract::The ocular penetration of two beta-adrenergic blockers, befunolol and timolol, was studied using albino and pigmented rabbits. A 1% ophthalmic solution of 14C-befunolol hydrochloride or 14C-timolol maleate was instilled in one eye of nonsedated rabbits, and the concentrations of radioactive material in the ocular tiss...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Conventional vitreoretinal surgery for proliferative vitreoretinopathy is unsatisfactory despite numerous innovations over the past 20 years. Silicone oil injections in this series resulted in 70% reattachment of these end-stage cases, but within twelve months over 90% had no useful visual result. The development of a...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to investigate the usefulness of laser speckle flowgraphy (LSFG) for the differentiation of acute nonarteritic ischemic optic neuropathy (NAION) from anterior optic neuritis (ON). METHODS:To investigate blood flow in the optic disc under normal conditions, NAION, and anterior ON, we c...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-013-0246-8
更新日期:2013-07-01 00:00:00
abstract::Cell population and proportion of each component cell type in preretinal membranes formed after retinal detachment were studied by light microscopy (LM) and transmission electron microscopy (TEM). The preretinal membranes were surgically obtained from 20 proliferative vitreoretinopathy (PVR) and 7 macular pucker patie...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:To verify the current Japanese classification of vision disability in regard to visual acuity. METHODS:A questionnaire was sent to 100 ophthalmology services in Japan. Each service was asked to extract 300 of their outpatient records. From these records, patients who had a sum of corrected visual acuity in bot...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10384-011-0081-8
更新日期:2011-11-01 00:00:00
abstract:PURPOSE:To evaluate the effect of tetramethylpyrazine on the elevation of aqueous flare and intraocular pressure (IOP) induced by prostaglandin (PG) E(2) and PGE(2) receptor (EP) agonists. METHODS:PGE(2) or EP agonists (11-deoxy PGE(1), EP(2) agonist; 17-phenyl trinor PGE(2), EP(1) and EP(3) agonist; or sulprostone, E...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0021-5155(01)00320-3
更新日期:2001-05-01 00:00:00
abstract:PURPOSE:To compare the visualization of microaneurysms (MAs) in patients with diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA) with that using fluorescein angiography (FA). STUDY DESIGN:Prospective, clinical, and experimental. METHODS:This study was a prospective evaluation of imaging t...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-018-0570-0
更新日期:2018-03-01 00:00:00
abstract::The usefulness of the Fluorotron Master fluorophotometer fitted with a small animal adapter was evaluated with tree shrews. We also determined that the optimal measurement parameters for these animals, which are regarded as promising for experimental use in ophthalmic research, are: fluorescein-Na concentration, 0.5 x...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::For the past 30 years, I have worked as a physician-scientist in both the clinic and laboratory setting at a number of university medical schools. Encountering patients in the clinic for whom treatment was not available led me to the laboratory in an attempt to develop the appropriate treatment for future patients. Th...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10384-012-0165-0
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:We previously reported that human conjunctival epithelial cells expressed functioning interleukin-4 receptor α (IL-4Rα). In this study, we investigated whether human corneal epithelial cells also express functioning IL-4Rα. METHODS:The presence of IL-4Rα mRNA and protein in human corneal epithelium was examine...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-011-0030-6
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:The new microemulsion preconcentrate (MEPC) formulation of ciclosporin has been developed to reduce problems in intestinal absorption and to stabilize fluctuations in blood levels. A multicenter, open-label clinical trial of MEPC was conducted to assess its efficacy and safety in Behçet's disease patients with ...
journal_title:Japanese journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/s0021-5155(99)00025-8
更新日期:1999-07-01 00:00:00
abstract::Astrocytes were cultured from the cerebral cortices of newborn rabbits and were so confirmed by staining of the glial fibrillary acidic protein (GFAP). In Experiment I, the astrocytes of newborn rabbits of both sexes from one mother were pooled and suspended in a culture medium, and approximately 1-2 X 10(4) cells wer...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:To report optical coherence tomography (OCT) findings of macular edema secondary to retinal arterial macroaneurysms. METHODS:Six eyes with retinal arterial macroaneurysms were retrospectively examined by OCT. All eyes had macular edema without massive macular hemorrhage. Fluorescein angiography was performed i...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-006-0347-0
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:To evaluate the repeatability of corneal deformation parameters measured using a dynamic Scheimpflug analyzer and the impact of baseline clinical factors on the repeatability of each parameter. STUDY DESIGN:Retrospective, cross-sectional study. METHODS:Forty-eight eyes (48 healthy subjects; mean age, 49.0 ± 1...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:10.1007/s10384-017-0534-9
更新日期:2017-11-01 00:00:00
abstract::We examined ophthalmologically five affected members of a family with type IIa hyperlipoproteinemia. All of them had increased levels of cholesterol and low-density lipoprotein. Corneal arcus was found in three of the five members; a 50-year-old man, a 43-year-old woman and a 13-year-old boy. We believe that the corne...
journal_title:Japanese journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00