Abstract：
:In populations of Drosophila larvae, both, an aggregation and a dispersal behavior can be observed. However, the mechanisms coordinating larval locomotion in respect to other animals, especially in close proximity and during/after physical contacts are currently only little understood. Here we test whether relevant information is perceived before or during larva-larva contacts, analyze its influence on behavior and ask whether larvae avoid or pursue collisions. Employing frustrated total internal reflection-based imaging (FIM) we first found that larvae visually detect other moving larvae in a narrow perceptive field and respond with characteristic escape reactions. To decipher larval locomotion not only before but also during the collision we utilized a two color FIM approach (FIM(2c)), which allowed to faithfully extract the posture and motion of colliding animals. We show that during collision, larval locomotion freezes and sensory information is sampled during a KISS phase (german: Kollisions Induziertes Stopp Syndrom or english: collision induced stop syndrome). Interestingly, larvae react differently to living, dead or artificial larvae, discriminate other Drosophila species and have an increased bending probability for a short period after the collision terminates. Thus, Drosophila larvae evolved means to specify behaviors in response to other larvae.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Otto N,Risse B,Berh D,Bittern J,Jiang X,Klämbt Cdoi
10.1038/srep31564subject
Has Abstractpub_date
2016-08-11 00:00:00pages
31564issn
2045-2322pii
srep31564journal_volume
6pub_type
杂志文章abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-60882-x
更新日期：2020-03-02 00:00:00
abstract：:The association between perioperative blood transfusion (PBT) with adverse oncological outcomes have been previously reported in multiple malignancies including RCC. Nevertheless, the importance of transfusion timing is still unclear. The primary purpose of this study is to appraise whether the receipt of intraoperati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37691-4
更新日期：2019-02-04 00:00:00
abstract：:Aquaporin 9 (AQP9), as an aquaglyceroporin, is expressed in many immune cells and plays important role in tumor initiation and progression. However, the relationship between AQP9 and tumor-infiltrating cells, and its prognostic value in cancers still require comprehensive understanding. Herein, we aimed to elucidate t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-77657-z
更新日期：2020-11-27 00:00:00
abstract：:While carbon-based materials have spearheaded numerous breakthroughs in biomedicine, they also have procreated many logical concerns on their overall toxicity. Carbon dots (CDs) as a respectively new member have been extensively explored in nucleus directed delivery and bioimaging due to their intrinsic fluorescence p...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-70796-3
更新日期：2020-08-17 00:00:00
abstract：:Known susceptibility loci together can only explain about 6-8% of the disease heritability of IgA nephropathy (IgAN), suggesting that there are still a large number of genetic variants remained to be discovered. We previously identified IgAN and systemic lupus erythematosus (SLE)/lupus nephritis (LN) shared many loci ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35781
更新日期：2016-11-02 00:00:00
abstract：:The cartilaginous and non-neopterygian bony fishes have an electric sense typically comprised of hundreds or thousands of sensory canals distributed in broad clusters over the head. This morphology facilitates neural encoding of local electric field intensity, orientation, and polarity, used for determining the positi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08962
更新日期：2015-03-11 00:00:00
abstract：:This is the first study to demonstrate that colour transformations in the volume of a photochromic material (PM) are induced at the intersections of two control light channels, one controlling PM colouration and the other controlling decolouration. Thus, PM colouration is induced by position selectivity, and therefore...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31543
更新日期：2016-08-16 00:00:00
abstract：:Proteins are of interest in nano-bio electronic devices due to their versatile structures, exquisite functionality and specificity. However, quantum transport measurements produce conflicting results due to technical limitations whereby it is difficult to precisely determine molecular orientation, the nature of the mo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39792
更新日期：2017-01-04 00:00:00
abstract：:Fluid-feeding insects have evolved a unique strategy to distribute the labor between a liquid-acquisition device (proboscis) and a sucking pump. We theoretically examined physical constraints associated with coupling of the proboscis and sucking pump into a united functional organ. Classification of fluid feeders with...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06391-w
更新日期：2017-07-26 00:00:00
abstract：:Studies suggest that chromium deficiency is associated with elevated levels of fasting blood glucose, circulating insulin, cholesterol and triglycerides, and decreased proportion of lean body mass. However, data directly relating chromium levels to metabolic syndrome (MetS) risk are lacking. A total of 3,648 American ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep15606
更新日期：2015-10-22 00:00:00
abstract：:New computer vision solutions combined with artificial intelligence algorithms can help recognize patterns in biological images, reducing subjectivity and optimizing the analysis process. The aim of this study was to propose an approach based on interactive and traditional machine learning methods to classify soybean ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68273-y
更新日期：2020-07-09 00:00:00
abstract：:Ultrafast thermomechanical responses and spallation behaviours of monocrystal copper films irradiated by femtosecond laser pulse are investigated using molecular dynamics simulation (MDS). Films with 〈100〉, 〈110〉 and 〈111〉 crystal orientations along the thickness direction were studied. The results show that the cryst...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09559-6
更新日期：2017-08-23 00:00:00
abstract：:The brain lacks a traditional lymphatic system for metabolite clearance. The existence of a "glymphatic system" where metabolites are removed from the brain's extracellular space by convective exchange between interstitial fluid (ISF) and cerebrospinal fluid (CSF) along the paravascular spaces (PVS) around cerebral bl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66887-w
更新日期：2020-06-22 00:00:00
abstract：:Wolfram syndrome (WS) is a recessive multisystem disorder defined by the association of diabetes mellitus and optic atrophy, reminiscent of mitochondrial diseases. The role played by mitochondria remains elusive, with contradictory results on the occurrence of mitochondrial dysfunction. We evaluated 13 recessive WS pa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61735-3
更新日期：2020-03-16 00:00:00
abstract：:Analysis of intact glycopeptides by mass spectrometry is essential to determining the microheterogeneity of protein glycosylation. Higher-energy collisional dissociation (HCD) fragmentation of glycopeptides generates mono- or disaccharide ions called oxonium ions that carry information about the structure of the fragm...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37189
更新日期：2016-11-21 00:00:00
abstract：:Cytotoxic T lymphocyte-associated antigen 4 immunoglobulin fusion protein (CTLA4Ig, abatacept) is a B7/CD28 costimulation inhibitor that can ward off the immune response by preventing the activation of naïve T cells. This therapeutic agent is administered to patients with autoimmune diseases such as rheumatoid arthrit...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06935
更新日期：2014-11-06 00:00:00
abstract：:Vocal expression of emotions has been suggested to be conserved throughout evolution. However, since vocal indicators of emotions have never been compared between closely related species using similar methods, it remains unclear whether this is the case. Here, we investigated vocal indicators of emotional valence (neg...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09437-1
更新日期：2017-08-18 00:00:00
abstract：:CoO nanocrystal/graphene nanosheets (GNS) composites, consisting of a triangular CoO nanocrystal of 2~20 nm on the surface of GNS, are synthesized by a mild synthetic method. First, cobalt acetate tetrahydrate is recrystallized in the alcohol solution at a low temperature. Then, graphene oxide mixed with cobalt-precur...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10017
更新日期：2015-05-11 00:00:00
abstract：:The anisotropic hole and electron mobilities in N,N'-3,4,9,10-perylenediimide-1,7-phenoxy (PDIB-2OPh) and N,N'-3,4,9,10-perylenediimide (PDIB) were theoretically predicted using the Marcus-Hush theory. The substituent effect of phenoxy on their mobility rates, absorption spectra, electron affinities, and ionization po...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35555
更新日期：2016-10-19 00:00:00
abstract：:Lavender (Lavandula angustifolia) is an important economic plant because of the value of its essential oil (EO). The Yili Valley in Xinjiang has become the largest lavender planting base in China. However, there is a lack of research on the gene expression regulation of EO biosynthesis and metabolism in local varietie...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-63950-4
更新日期：2020-04-24 00:00:00
abstract：:A novel protein, designated as DOI, isolated from the Chinese yam (Dioscorea opposita Thunb.) could be the first protein drug for the treatment of menopausal syndrome and an alternative to hormone replacement therapy (HRT), which is known to have undesirable side effects. DOI is an acid- and thermo-stable protein with...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10179
更新日期：2015-07-10 00:00:00
abstract：:CD96 is a promising candidate for immunotherapy. However, its role and importance in glioma remains unknown. We thus aimed to genetically and clinically characterize CD96 expression in gliomas. For this, we extracted RNA-seq data of 699 glioma samples from the TCGA dataset and validated these findings using the CGGA d...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66806-z
更新日期：2020-07-01 00:00:00
abstract：:This study aimed to investigate the possible association between diabetes susceptibility gene transcription factor 7-like 2 (TCF7L2) and gestational diabetes mellitus (GDM) in a Chinese Han population. A total of 556 GDM patients and 500 Non-GDM were included. Eighteen single nucleotide polymorphisms (SNPs) were evalu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30686
更新日期：2016-07-28 00:00:00
abstract：:The development of novel small molecule inhibitors of the cancer-associated tropomyosin 3.1 (Tpm3.1) provides the ability to examine the metabolic function of specific actin filament populations. We have determined the ability of these anti-Tpm (ATM) compounds to regulate glucose metabolism in mice. Acute treatment (1...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22946-x
更新日期：2018-03-15 00:00:00
abstract：:Restless Legs syndrome (RLS) is a common sleep disorder for which the genetic contribution remains poorly explained. In 2007, the first large scale genome wide association study (GWAS) identified three genomic regions associated with RLS. MEIS1, BTBD9 and MAP2K5/SKOR1 are the only known genes located within these loci...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30665-6
更新日期：2018-08-15 00:00:00
abstract：:Methods to repair bone defects arising from trauma, resection, or disease, continue to be sought after. Cyclic mechanical loading is well established to influence bone (re)modelling activity, in which bone formation and resorption are correlated to micro-scale strain. Based on this, the application of mechanical stimu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81132-8
更新日期：2021-01-21 00:00:00
abstract：:The unconventional myosin MYO18A that contains a PDZ domain is required for muscle integrity during zebrafish development. However, the mechanism by which it functions in myofibers is not clear. The presence of a PDZ domain suggests that MYO18A may interact with other partners to perform muscle-specific functions. Her...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36768
更新日期：2016-11-08 00:00:00
abstract：:Aluminium adjuvants remain the most widely used and effective adjuvants in vaccination and immunotherapy. Herein, the particle size distribution (PSD) of aluminium oxyhydroxide and aluminium hydroxyphosphate adjuvants was elucidated in attempt to correlate these properties with the biological responses observed post v...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31578
更新日期：2016-08-12 00:00:00
abstract：:Circulating levels of Brain Derived Neurotrophic Factor (BDNF) are lower in coronary heart disease (CHD) than in healthy subjects and are associated with coronary events and mortality. However, the mechanism(s) underling this association is not fully understood. We hypothesize that BDNF may influence fibrin fiber stru...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/s41598-018-37117-1
更新日期：2019-01-23 00:00:00
abstract：:Alignment-free methods, in which shared properties of sub-sequences (e.g. identity or match length) are extracted and used to compute a distance matrix, have recently been explored for phylogenetic inference. However, the scalability and robustness of these methods to key evolutionary processes remain to be investigat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06504
更新日期：2014-09-30 00:00:00
