Novel identified associations of RGS1 and RASGRP1 variants in IgA Nephropathy.

abstract：:When estimating national PM2.5 concentrations, the results of traditional interpolation algorithms are unreliable due to a lack of monitoring sites and heterogeneous spatial distributions. PM2.5 spatial distribution is strongly correlated to elevation, and the information diffusion algorithm has been shown to be highl...

journal_title：Scientific reports

authors： Ma L,Gao Y,Fu T,Cheng L,Chen Z,Li M

更新日期：2017-11-14 00:00:00

abstract：:Cardiovascular diseases are directly linked to smoking habits, which has both physiological and anatomical effects on the systemic and retinal circulations, and these changes can be detected with fundus photographs. Here, we aimed to 1- design a Convolutional Neural Network (CNN), using retinal photographs, to differe...

journal_title：Scientific reports

authors： Vaghefi E,Yang S,Hill S,Humphrey G,Walker N,Squirrell D

更新日期：2019-05-09 00:00:00

abstract：:From mid-May to August 2011, extreme runoff in the Columbia River ranged from 14,000 to over 17,000 m(3)/s, more than two standard deviations above the mean for this period. The extreme runoff was the direct result of both melting of anomalously high snowpack and rainfall associated with the 2010-2011 La Niña. The eff...

journal_title：Scientific reports

authors： Mazzini PL,Risien CM,Barth JA,Pierce SD,Erofeev A,Dever EP,Kosro PM,Levine MD,Shearman RK,Vardaro MF

更新日期：2015-11-26 00:00:00

abstract：:In situ HfB2-SiC-VSi2 composite was fabricated by reactive pressureless sintering at the temperature of 2150 °C for 4 h under a vacuum atmosphere. In situ SiC and VSi2 reinforcements were formed using VC and Si powders as starting materials according to the following reaction: VC + 3Si = SiC + VSi2. Microstructural st...

journal_title：Scientific reports

authors： Ghadami S,Taheri-Nassaj E,Baharvandi HR,Ghadami F

更新日期：2020-10-06 00:00:00

abstract：:Proteasomes are a critical component of quality control that regulate turnover of short-lived, unfolded, and misfolded proteins. Proteasome activity has been therapeutically targeted and considered as a treatment option for several chronic lung disorders including pulmonary fibrosis. Although pharmacologic inhibition ...

journal_title：Scientific reports

authors： Sitaraman S,Na CL,Yang L,Filuta A,Bridges JP,Weaver TE

更新日期：2019-08-29 00:00:00

abstract：:Semen fertilizing potential is dependent upon the morphological, functional and molecular attributes of sperm. Sperm microRNAs (miRNAs) were recently shown to hold promise regarding their association with different fertility phenotypes. However, their role in fertility regulation remains to be determined. We postulate...

journal_title：Scientific reports

authors： Alves MBR,de Arruda RP,De Bem THC,Florez-Rodriguez SA,Sá Filho MF,Belleannée C,Meirelles FV,da Silveira JC,Perecin F,Celeghini ECC

更新日期：2019-07-17 00:00:00

abstract：:Biomedical researchers often encounter the large-p-small-n situations-a great number of variables are measured/recorded for only a few subjects. The authors propose a fuzzy permutation method to address the multiple testing problem for small sample size studies. The method introduces fuzziness into standard permutatio...

journal_title：Scientific reports

authors： Yang YH,Lin WY,Lee WC

更新日期：2016-06-22 00:00:00

abstract：:Autosomal dominant North Carolina macular dystrophy (NCMD) is believed to represent a failure of macular development. The disorder has been linked to two loci, MCDR1 (chromosome 6q16) and MCDR3 (chromosome 5p15-p13). Recently, non-coding variants upstream of PRDM13 (MCDR1) and a duplication including IRX1 (MCDR3) have...

journal_title：Scientific reports

authors： Cipriani V,Silva RS,Arno G,Pontikos N,Kalhoro A,Valeina S,Inashkina I,Audere M,Rutka K,Puech B,Michaelides M,van Heyningen V,Lace B,Webster AR,Moore AT

更新日期：2017-08-08 00:00:00

abstract：:Two objects can be distinguished if they have different measurable properties. Thus, distinguishability depends on the Physics of the objects. In considering graphs, we revisit the Ising model as a framework to define physically meaningful spectral invariants. In this context, we introduce a family of refinements of t...

journal_title：Scientific reports

authors： Vinci W,Markström K,Boixo S,Roy A,Spedalieri FM,Warburton PA,Severini S

更新日期：2014-07-16 00:00:00

abstract：:The habit of blood feeding evolved independently in many insect orders of families. Sand flies and mosquitoes belong to separate lineages of blood-feeding Diptera and are thus considered to have evolved the trait independently. Because of this, sand fly salivary proteins differ structurally from those of mosquitoes, a...

journal_title：Scientific reports

authors： Jablonka W,Kim IH,Alvarenga PH,Valenzuela JG,Ribeiro JMC,Andersen JF

更新日期：2019-03-29 00:00:00

abstract：:Semi-arid ecosystems are key contributors to the global carbon cycle and may even dominate the inter-annual variability (IAV) and trends of the land carbon sink, driven largely by the El Niño-Southern Oscillation (ENSO). The linkages between dynamics of semi-arid ecosystems and climate at the hemispheric scale however...

journal_title：Scientific reports

authors： Zhang A,Jia G,Epstein HE,Xia J

更新日期：2017-02-09 00:00:00

abstract：:Electrospun gelatin nanofibers attract great interest as a natural biomaterial for cartilage and tendon repair despite their high solubility in aqueous solution, which makes them also difficult to crosslink by means of chemical agents. In this work, we explore the efficiency of non-equilibrium atmospheric pressure pla...

journal_title：Scientific reports

authors： Liguori A,Bigi A,Colombo V,Focarete ML,Gherardi M,Gualandi C,Oleari MC,Panzavolta S

更新日期：2016-12-07 00:00:00

abstract：:Rett syndrome (RTT) is a neurodevelopmental disorder mainly caused by mutations in the gene encoding the transcriptional regulator Methyl-CpG-binding protein 2 (MeCP2), located on the X chromosome. Many RTT patients have breathing abnormalities, such as apnea and breathing irregularity, and respiratory infection is th...

journal_title：Scientific reports

authors： Kida H,Takahashi T,Nakamura Y,Kinoshita T,Hara M,Okamoto M,Okayama S,Nakamura K,Kosai KI,Taniwaki T,Yamashita Y,Matsuishi T

更新日期：2017-09-20 00:00:00

abstract：:Accidental introduction through ballast water and biofouling are currently the main factors responsible for spreading non-indigenous species in the marine realm. In the Southwestern Atlantic, two scleractinian corals, Tubastraea coccinea and T. tagusensis, have been introduced by opportunistic colonization in 1980 and...

journal_title：Scientific reports

authors： Capel KCC,Creed J,Kitahara MV,Chen CA,Zilberberg C

更新日期：2019-09-27 00:00:00

abstract：:The dispersion of organic N-benzyl-2-methyl-4-nitroaniline (BNA) in nematic liquid crystals (LCs) is studied. BNA doping decreases the threshold voltage of cell because of the reduced splay elastic constant and increased dielectric anisotropy of the LC mixture. When operated in the high voltage difference condition, t...

journal_title：Scientific reports

authors： Selvaraj P,Subramani K,Srinivasan B,Hsu CJ,Huang CY

更新日期：2020-08-31 00:00:00

abstract：:The mobilities of electrons and holes determine the applicability of any semiconductor, but their individual measurement remains a major challenge. Here, we show that time-resolved terahertz spectroscopy (TRTS) can distinguish the mobilities of minority and majority charge carriers independently of the doping-type and...

journal_title：Scientific reports

authors： Hempel H,Hages CJ,Eichberger R,Repins I,Unold T

更新日期：2018-09-27 00:00:00

abstract：:To investigate the mechanism underlying AT1-AA-induced retinopathy in severe preeclampsia by measuring the positive rate and titer of AT1-AA in plasma from women with severe preeclampsia and normal pregnant women to see whether AT1-AA titer was correlated with the grade of retinopathy. A preeclampsia rat model was als...

journal_title：Scientific reports

authors： Liu F,Wang Y,Wang X,Zheng Y,Jin Z,Zhi J

更新日期：2016-07-06 00:00:00

abstract：:Previous observational studies supported a positive association of glycated hemoglobin A1c (HbA1c) level with serum triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). However, the causal relationship between HbA1c and either one of ...

journal_title：Scientific reports

authors： Jia X,Hou Y,Xu M,Zhao Z,Xuan L,Wang T,Li M,Xu Y,Lu J,Bi Y,Wang W,Chen Y

更新日期：2019-04-02 00:00:00

abstract：:Pesticides, including neonicotinoids, typically target pest insects by being neurotoxic. Inadvertent exposure to foraging insect pollinators is usually sub-lethal, but may affect cognition. One cognitive trait, spatial working memory, may be important in avoiding previously-visited flowers and other spatial tasks such...

journal_title：Scientific reports

authors： Samuelson EE,Chen-Wishart ZP,Gill RJ,Leadbeater E

更新日期：2016-12-13 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Huang S,Sun C,Hou Y,Tang Y,Zhu Z,Zhang Z,Zhang Y,Wang L,Zhao Q,Chen MG,Guo Z,Wang D,Ju W,Zhou Q,Wu L,He X

更新日期：2019-05-03 00:00:00

abstract：:Visceral leishmaniasis (VL) is a fatal form of leishmaniasis which affects 70 countries, worldwide. Increasing drug resistance, HIV co-infection, and poor health system require operative vaccination strategy to control the VL transmission dynamics. Therefore, a holistic approach is needed to generate T and B memory ce...

journal_title：Scientific reports

authors： Khatoon N,Pandey RK,Prajapati VK

更新日期：2017-08-15 00:00:00

abstract：:We investigated how the organization of functional brain networks was related to cognitive reserve (CR) during a memory task in healthy aging. We obtained the magnetoencephalographic functional networks of 20 elders with a high or low CR level to analyse the differences at network features. We reported a negative corr...

journal_title：Scientific reports

authors： Martínez JH,López ME,Ariza P,Chavez M,Pineda-Pardo JA,López-Sanz D,Gil P,Maestú F,Buldú JM

更新日期：2018-07-12 00:00:00

abstract：:Unwanted clots lead to heart attack and stroke that result in a large number of deaths. Currently available anticoagulants have some drawbacks including their non-specific actions. Therefore novel anticoagulants that target specific steps in the coagulation pathway are being sought. Here we describe the identification...

journal_title：Scientific reports

authors： Girish VM,Kini RM

更新日期：2016-08-25 00:00:00

abstract：:SeviL is a recently isolated lectin found to bind to the linear saccharides of the ganglioside GM1b (Neu5Ac[Formula: see text](2-3)Gal[Formula: see text](1-3)GalNAc[Formula: see text](1-4)Gal[Formula: see text](1-4)Glc) and its precursor, asialo-GM1 (Gal[Formula: see text](1-3)GalNAc[Formula: see text](1-4)Gal[Formula...

journal_title：Scientific reports

authors： Kamata K,Mizutani K,Takahashi K,Marchetti R,Silipo A,Addy C,Park SY,Fujii Y,Fujita H,Konuma T,Ikegami T,Ozeki Y,Tame JRH

更新日期：2020-12-16 00:00:00

abstract：:Optical polarizing devices exploiting graphene embedded in waveguides have been demonstrated in the literature recently and both the TE- and TM-pass behaviors were reported. The determination of the passing polarization is usually attributed to graphene's Fermi level (and, therefore, doping level), with, however, no d...

journal_title：Scientific reports

authors： de Oliveira RE,de Matos CJ

更新日期：2015-11-19 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Stringer BW,Day BW,D'Souza RCJ,Jamieson PR,Ensbey KS,Bruce ZC,Lim YC,Goasdoué K,Offenhäuser C,Akgül S,Allan S,Robertson T,Lucas P,Tollesson G,Campbell S,Winter C,Do H,Dobrovic A,Inglis PL,Jeffree RL,Johns TG,Boy

更新日期：2020-01-21 00:00:00

abstract：:In an era of climate change, biological invasions by alien species represent one of the main anthropogenic drivers of global environmental change. The present study, using an ensemble modelling approach, has mapped current and future global distribution of the invasive Leucanthemum vulgare (Ox-eye Daisy) and predicted...

journal_title：Scientific reports

authors： Ahmad R,Khuroo AA,Charles B,Hamid M,Rashid I,Aravind NA

更新日期：2019-08-06 00:00:00

abstract：:The seed storage proteins of soybean (Glycine max) are composed mainly of glycinin (11S globulin) and β-conglycinin (7S globulin). The subunits of glycinin (A1aB1b, A1bB2, A2B1a, A3B4, and A5A4B3) are synthesized as a single polypeptide precursor. These precursors are assembled into trimers with a random combination o...

journal_title：Scientific reports

authors： Maruyama N,Matsuoka Y,Yokoyama K,Takagi K,Yamada T,Hasegawa H,Terakawa T,Ishimoto M

更新日期：2018-01-18 00:00:00

abstract：:Rice yield have been affected by the increased extreme precipitation events in recent decades. Yet, the spatio-temporal patterns of extreme precipitation by rice type and phenology remain elusive. Here, we investigate the characteristics of four extreme precipitation indices across China's rice paddy and their potenti...

journal_title：Scientific reports

authors： Jian Y,Fu J,Li B,Zhou F

更新日期：2020-06-30 00:00:00

abstract：:Antimicrobial peptides (AMPs) are peptide antibiotics with a broad spectrum of antimicrobial activities. Activity prediction of AMPs from their amino acid sequences is of great therapeutic importance but imposes challenges on prediction methods due to label interactions. In this paper we propose a novel multi-label le...

journal_title：Scientific reports

authors： Wang P,Ge R,Liu L,Xiao X,Li Y,Cai Y

更新日期：2017-05-19 00:00:00