A Novel, Stable, Estradiol-Stimulating, Osteogenic Yam Protein with Potential for the Treatment of Menopausal Syndrome.

abstract：:Medication-related osteonecrosis of the jaw (MRONJ) represents a complication of bisphosphonate treatment that responds poorly to standard treatment. In a retrospective cohort study we investigated a possible role of Actinomyces spp. in the pathogenesis of MRONJ. Deep biopsies of necrotic bone were collected during su...

journal_title：Scientific reports

authors： Russmueller G,Seemann R,Weiss K,Stadler V,Speiss M,Perisanidis C,Fuereder T,Willinger B,Sulzbacher I,Steininger C

更新日期：2016-08-17 00:00:00

abstract：:Overuse of nitrogen (N) fertilizer has led to low N use efficiency (NUE) and high N loss in single rice cropping systems in southeast China. Application of controlled-release urea (CRU) is considered as an effective N fertilizer practice for improving crop yields and NUE. Here, field experiments were conducted during ...

journal_title：Scientific reports

authors： Chen Z,Wang Q,Ma J,Zou P,Jiang L

更新日期：2020-06-26 00:00:00

abstract：:The immune system is constantly challenged, being required to protect the organism against a wide variety of infectious pathogens and, at the same time, to avoid autoimmune disorders. One of the most important molecules involved in these events is the Major Histocompatibility Complex class I (MHC-I), responsible for b...

journal_title：Scientific reports

authors： Rigo MM,Antunes DA,Vaz de Freitas M,Fabiano de Almeida Mendes M,Meira L,Sinigaglia M,Vieira GF

更新日期：2015-12-17 00:00:00

abstract：:The pine wood nematode, Bursaphelenchus xylophilus, is the causal agent of pine wilt disease that has devastated pine forests in Asia. Parasitic nematodes are known to have evolved antioxidant stress responses that defend against host plant defenses. In this study, the infestation of whitebark pine, Pinus bungean, wit...

journal_title：Scientific reports

authors： Li Z,Zhang Q,Zhou X

更新日期：2016-06-07 00:00:00

abstract：:The hitherto difficult task of reliably estimating populations of wide-ranging megafauna has been enabled by advances in capture-recapture methodology. Here we combine photographic sampling with a Bayesian spatially-explicit capture-recapture (SCR) model to estimate population parameters for the endangered Asian eleph...

journal_title：Scientific reports

authors： Goswami VR,Yadava MK,Vasudev D,Prasad PK,Sharma P,Jathanna D

更新日期：2019-06-12 00:00:00

abstract：:We demonstrate fluorescent Fe embedded magnetic nanodiamonds by ion implantation and two-step annealing. The diamond characteristics with a highly ordered core and a graphite surface layer are maintained after the implantation process. After the two-step annealing process, a bright red fluorescence associated with nit...

journal_title：Scientific reports

authors： Lin BR,Kunuku S,Chen CH,Chen TY,Hsiao TY,Yu HK,Chang YJ,Liao LC,Niu H,Lee CP

更新日期：2019-02-04 00:00:00

abstract：:The first instar larva of a species of the Australian endemic genus Aenigmetopia Malloch is described for the first time, along with the first instar larvae of three other Australian species representing the genera Amobia Robineau-Desvoidy and Protomiltogramma Townsend. Larval morphology was analysed using a combinati...

journal_title：Scientific reports

authors： Szpila K,Walczak K,Johnston NP,Pape T,Wallman JF

更新日期：2021-01-29 00:00:00

abstract：:Inflammation plays central roles in the immune response. Inflammatory response normally requires higher energy and therefore is associated with glucose metabolism. Our recent study demonstrates that lncRNA HOTAIR plays key roles in NF-kB activation, cytokine expression, and inflammation. Here, we investigated if HOTAI...

journal_title：Scientific reports

authors： Obaid M,Udden SMN,Alluri P,Mandal SS

更新日期：2021-01-08 00:00:00

abstract：:Thermal rectifiers whose forward heat fluxes are greater than reverse counterparts have been extensively studied. Here we have discovered, idealized, and derived the ultimate limit of such rectification ratios, which are partially validated by numerical simulations, experiments, and micro-scale Hamiltonian-oscillator ...

journal_title：Scientific reports

authors： Shih TM,Gao Z,Guo Z,Merlitz H,Pagni PJ,Chen Z

更新日期：2015-08-04 00:00:00

abstract：:The competitive multi-armed bandit (CMAB) problem is related to social issues such as maximizing total social benefits while preserving equality among individuals by overcoming conflicts between individual decisions, which could seriously decrease social benefits. The study described herein provides experimental evide...

journal_title：Scientific reports

authors： Chauvet N,Jegouso D,Boulanger B,Saigo H,Okamura K,Hori H,Drezet A,Huant S,Bachelier G,Naruse M

更新日期：2019-08-22 00:00:00

abstract：:The serum macrophage inhibitory cytokine-1 (MIC-1) levels are elevated in some inflammatory conditions and cancers. We thus compared the levels of biliary and serum MIC-1 and conventional tumour markers between 23 biliary tract cancer (BTC) patients (malignant group) and 29 benign biliary disease patients (benign grou...

journal_title：Scientific reports

authors： Sugimoto M,Takagi T,Konno N,Suzuki R,Asama H,Watanabe K,Nakamura J,Waragai Y,Kikuchi H,Takasumi M,Sato Y,Hikichi T,Ohira H

更新日期：2017-08-23 00:00:00

abstract：:Connectivity is fundamentally important for shaping the resilience of complex human and natural networks when systems are disturbed. Ecosystem resilience is, in part, shaped by the spatial arrangement of habitats, the permeability and fluxes between them, the stabilising functions performed by organisms, their dispers...

journal_title：Scientific reports

authors： Pearson RM,Schlacher TA,Jinks KI,Olds AD,Brown CJ,Connolly RM

更新日期：2021-01-13 00:00:00

abstract：:There is a scarcity of data of zinc transporter-8 autoantibody (ZnT8A) on mixed populations such as Brazilian. Therefore, we evaluated the relevance of ZnT8A for type 1 diabetes (T1D) diagnosis and the role of ZnT8 coding gene (SLC30A8) in T1D predisposition. Patients with T1D (n = 629; diabetes duration = 11 (6-16) y...

journal_title：Scientific reports

authors： Gomes KF,Semzezem C,Batista R,Fukui RT,Santos AS,Correia MR,Passos-Bueno MR,Silva ME

更新日期：2017-03-16 00:00:00

abstract：:This paper presented a conformal smoothing theory, and smoothing capability evaluation was established on the proposed theory. According to pressure distribution model, processing parameters have been optimized and the CPP sample with a size of 340 × 340 mm was applied in conformal smoothing. The middle spatial freque...

journal_title：Scientific reports

authors： Song C,Zhang W,Shi F,Lin Z,Nie X

更新日期：2020-02-13 00:00:00

abstract：:Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic outputs-the efficacy of the synapses-plays a principal role in all aspects of hi...

journal_title：Scientific reports

authors： Dabaghian Y

更新日期：2019-01-24 00:00:00

abstract：:Epidemiologic studies have identified a positive association between obesity and colorectal neoplasia. Adiposity induces systemic low-grade inflammation, which is commonly assessed with a sensitive biomarker, C-reactive protein (CRP). To understand the molecular mechanisms of obesity in the etiology of colorectal neop...

journal_title：Scientific reports

authors： Kigawa N,Budhathoki S,Yamaji T,Iwasaki M,Inoue M,Tsugane S

更新日期：2017-06-30 00:00:00

abstract：:Archaeological evidence suggests that dogs were introduced to the islands of Oceania via Island Southeast Asia around 3,300 years ago, and reached the eastern islands of Polynesia by the fourteenth century AD. This dispersal is intimately tied to human expansion, but the involvement of dogs in Pacific migrations is no...

journal_title：Scientific reports

authors： Greig K,Gosling A,Collins CJ,Boocock J,McDonald K,Addison DJ,Allen MS,David B,Gibbs M,Higham CFW,Liu F,McNiven IJ,O'Connor S,Tsang CH,Walter R,Matisoo-Smith E

更新日期：2018-06-14 00:00:00

abstract：:The spreading of cooperation in structured population is a challenging problem which can be observed at different scales of social and biological organization. Generally, the problem is studied by evaluating the chances that few initial invading cooperators, randomly appearing in a network, can lead to the spreading o...

journal_title：Scientific reports

authors： Yang G,Cavaliere M,Zhu C,Perc M

更新日期：2021-01-13 00:00:00

abstract：:Diagnostic test accuracy of the loop-mediated isothermal amplification (LAMP) assay for culture proven tuberculosis is unclear. We searched electronic databases for both cohort and case-control studies that provided data to calculate sensitivity and specificity. The index test was any LAMP assay including both commerc...

journal_title：Scientific reports

authors： Nagai K,Horita N,Yamamoto M,Tsukahara T,Nagakura H,Tashiro K,Shibata Y,Watanabe H,Nakashima K,Ushio R,Ikeda M,Narita A,Kanai A,Sato T,Kaneko T

更新日期：2016-12-13 00:00:00

abstract：:Aneurysmal subarachnoid hemorrhage (aSAH)-induced cerebral vasospasm and delayed ischemic neurological deficit (DIND) are the major causes of morbidity and mortality in patients with aSAH. The effects of statins-use for patients with aSAH remain controversial. Here,a total of 249 patients from six randomized controlle...

journal_title：Scientific reports

authors： Su SH,Xu W,Hai J,Wu YF,Yu F

更新日期：2014-04-25 00:00:00

abstract：:Transposable elements (TEs) are genomic sequences that can move, multiply, and often form sizable fractions of vertebrate genomes. Fish belong to a unique group of vertebrates, since their karyotypes and genome sizes are more diverse and complex, with probably higher diversity and evolution specificity of TE. To inves...

journal_title：Scientific reports

authors： Shao F,Han M,Peng Z

更新日期：2019-10-28 00:00:00

abstract：:Natural variability in pH in the diffusive boundary layer (DBL), the discrete layer of seawater between bulk seawater and the outer surface of organisms, could be an important factor determining the response of corals and coralline algae to ocean acidification (OA). Here, two corals with different morphologies and one...

journal_title：Scientific reports

authors： Comeau S,Cornwall CE,Pupier CA,DeCarlo TM,Alessi C,Trehern R,McCulloch MT

更新日期：2019-09-06 00:00:00

abstract：:Neonatal hypoxic-ischaemic (HI) encephalopathy is among the most serious complications in neonatology. In the present study, we studied the immediate (0 hour), subacute (36 hours) and late (144 hours) responses of the neonatal brain to experimental HI insult in laboratory rats. At the striatal level, the mass spectrom...

journal_title：Scientific reports

authors： Luptakova D,Baciak L,Pluhacek T,Skriba A,Sediva B,Havlicek V,Juranek I

更新日期：2018-05-03 00:00:00

abstract：:Severe sepsis or septic shock is one of the rising causes for mortality worldwide representing nearly 10% of intensive care unit admissions. Susceptibility to sepsis is identified to be mediated by innate pattern recognition receptors and responsive signaling pathways of the host. The c-Jun N-terminal Kinase (JNK)-med...

journal_title：Scientific reports

authors： Prasad KD,Trinath J,Biswas A,Sekar K,Balaji KN,Guru Row TN

更新日期：2014-11-27 00:00:00

abstract：:Cystine-knot peptides are attractive templates in drug discovery due to a number of features they possess including their 3D conformation, physicochemical stability and synthetic tractability. Yet, their cellular uptake mechanisms remain largely unexplored. Recently, we demonstrated that the cystine-knot peptide EETI-...

journal_title：Scientific reports

authors： Gao X,De Mazière A,Iaea DB,Arthur CP,Klumperman J,Ciferri C,Hannoush RN

更新日期：2019-05-06 00:00:00

abstract：:Gapmer antisense oligonucleotides cleave target RNA effectively in vivo, and is considered as promising therapeutics. Especially, gapmers modified with locked nucleic acid (LNA) shows potent knockdown activity; however, they also cause hepatotoxic side effects. For developing safe and effective gapmer drugs, a deeper ...

journal_title：Scientific reports

authors： Kasuya T,Hori S,Watanabe A,Nakajima M,Gahara Y,Rokushima M,Yanagimoto T,Kugimiya A

更新日期：2016-07-27 00:00:00

abstract：:Traumatic brain injury (TBI) has been associated with atherosclerosis and cardiovascular mortality in humans. However the causal relationship between TBI and vascular disease is unclear. This study investigated the direct role of TBI on vascular disease using a murine model of atherosclerosis. Apolipoprotein E deficie...

journal_title：Scientific reports

authors： Wang J,Su E,Wang H,Guo C,Lawrence DA,Eitzman DT

更新日期：2018-04-04 00:00:00

abstract：:Photoluminescence and photomodulated reflectivity measurements of ZnOSe alloys are used to demonstrate a splitting of the valence band due to the band anticrossing interaction between localized Se states and the extended valence band states of the host ZnO matrix. A strong multiband emission associated with optical tr...

journal_title：Scientific reports

authors： Welna M,Baranowski M,Linhart WM,Kudrawiec R,Yu KM,Mayer M,Walukiewicz W

更新日期：2017-03-13 00:00:00

abstract：:Genetic circuit-based biosensors have emerged as an effective analytical tool in synthetic biology; these biosensors can be applied to high-throughput screening of new biocatalysts and metabolic pathways. Sigma 54 (σ54)-dependent transcription factor (TF) can be a valuable component of these biosensors owing to its in...

journal_title：Scientific reports

authors： Kwon KK,Yeom SJ,Choi SL,Rha E,Lee H,Kim H,Lee DH,Lee SG

更新日期：2020-04-08 00:00:00

abstract：:Biological armors such as mollusk shells have long been recognized and studied for their values in inspiring novel designs of engineering materials with higher toughness and strength. However, no material is invincible and biological armors also have their rivals. In this paper, our attention is focused on the teeth o...

journal_title：Scientific reports

authors： Fu J,He C,Xia B,Li Y,Feng Q,Yin Q,Shi X,Feng X,Wang H,Yao H

更新日期：2016-03-22 00:00:00