Turning the respiratory flexibility of Mycobacterium tuberculosis against itself.

abstract：:Electrochemical water splitting requires efficient water oxidation catalysts to accelerate the sluggish kinetics of water oxidation reaction. Here, we report a promisingly dendritic core-shell nickel-iron-copper metal/metal oxide electrode, prepared via dealloying with an electrodeposited nickel-iron-copper alloy as a...

journal_title：Nature communications

authors： Zhang P,Li L,Nordlund D,Chen H,Fan L,Zhang B,Sheng X,Daniel Q,Sun L

更新日期：2018-01-26 00:00:00

abstract：:The precise molecular mechanism underlying the regulation of early B cell lymphopoiesis is unclear. The PLCγ signaling pathway is critical for antigen receptor-mediated lymphocyte activation, but its function in cytokine signaling is unknown. Here we show that PLCγ1/PLCγ2 double deficiency in mice blocks early B cell ...

journal_title：Nature communications

authors： Yu M,Chen Y,Zeng H,Zheng Y,Fu G,Zhu W,Broeckel U,Aggarwal P,Turner A,Neale G,Guy C,Zhu N,Chi H,Wen R,Wang D

更新日期：2017-11-13 00:00:00

abstract：:Superlubricity of graphite and graphene has aroused increasing interest in recent years. Yet how to obtain a long-lasting superlubricity between graphene layers, under high applied normal load in ambient atmosphere still remains a challenge but is highly desirable. Here, we report a direct measurement of sliding frict...

journal_title：Nature communications

authors： Liu SW,Wang HP,Xu Q,Ma TB,Yu G,Zhang C,Geng D,Yu Z,Zhang S,Wang W,Hu YZ,Wang H,Luo J

更新日期：2017-02-14 00:00:00

abstract：:Evidence from animal and human studies has suggested that the amygdala plays a role in detecting threat and in directing attention to the eyes. Nevertheless, there has been no systematic investigation of whether the amygdala specifically facilitates attention to the eyes or whether other features can also drive attent...

journal_title：Nature communications

authors： Dal Monte O,Costa VD,Noble PL,Murray EA,Averbeck BB

更新日期：2015-12-14 00:00:00

abstract：:Perovskite quantum-dot-based light-emitting diodes (QLEDs) possess the features of wide gamut and real color expression, which have been considered as candidates for high-quality lightings and displays. However, massive defects are prone to be reproduced during the quantum dot (QD) film assembly, which would sorely af...

journal_title：Nature communications

authors： Xu L,Li J,Cai B,Song J,Zhang F,Fang T,Zeng H

更新日期：2020-08-06 00:00:00

abstract：:Synonymous mutations have been viewed as silent mutations, since they only affect the DNA and mRNA, but not the amino acid sequence of the resulting protein. Nonetheless, recent studies suggest their significant impact on splicing, RNA stability, RNA folding, translation or co-translational protein folding. Hence, we ...

journal_title：Nature communications

authors： Sharma Y,Miladi M,Dukare S,Boulay K,Caudron-Herger M,Groß M,Backofen R,Diederichs S

更新日期：2019-06-12 00:00:00

abstract：:The stratospheric Arctic vortex (SAV) plays a critical role in forecasting cold winters in northern mid-latitudes. Its influence on the tropospheric mid- and high-latitudes has attracted growing attention in recent years. However, the trend in the SAV during the recent two decades is still unknown. Here, using three r...

journal_title：Nature communications

authors： Hu D,Guan Z,Tian W,Ren R

更新日期：2018-04-27 00:00:00

abstract：:Exploitation of drug-drug synergism and allostery could yield superior therapies by capitalizing on the immensely diverse, but highly specific, potential associated with the biological macromolecular landscape. Here we describe a drug-drug synergy mediated by allosteric cross-talk in chromatin, whereby the binding of ...

journal_title：Nature communications

authors： Adhireksan Z,Palermo G,Riedel T,Ma Z,Muhammad R,Rothlisberger U,Dyson PJ,Davey CA

更新日期：2017-03-30 00:00:00

abstract：:Understanding the biomolecular interactions between graphene and human immune cells is a prerequisite for its utilization as a diagnostic or therapeutic tool. To characterize the complex interactions between graphene and immune cells, we propose an integrative analytical pipeline encompassing the evaluation of molecul...

journal_title：Nature communications

authors： Orecchioni M,Bedognetti D,Newman L,Fuoco C,Spada F,Hendrickx W,Marincola FM,Sgarrella F,Rodrigues AF,Ménard-Moyon C,Cesareni G,Kostarelos K,Bianco A,Delogu LG

更新日期：2017-10-24 00:00:00

abstract：:Transcribing and replicating a double-stranded genome require protein modules to unwind, transcribe/replicate nucleic acid substrates, and release products. Here we present in situ cryo-electron microscopy structures of rotavirus dsRNA-dependent RNA polymerase (RdRp) in two states pertaining to transcription. In addit...

journal_title：Nature communications

authors： Ding K,Celma CC,Zhang X,Chang T,Shen W,Atanasov I,Roy P,Zhou ZH

更新日期：2019-05-17 00:00:00

abstract：:Considering the rapid increase of CO2 emission, especially from power plants, there is a constant need for materials which can effectively eliminate post-combustion CO2 (the main component: CO2/N2 = 15/85). Here, we show the design and synthesis of a Cu(II) metal-organic framework (FJI-H14) with a high density of acti...

journal_title：Nature communications

authors： Liang L,Liu C,Jiang F,Chen Q,Zhang L,Xue H,Jiang HL,Qian J,Yuan D,Hong M

更新日期：2017-11-01 00:00:00

abstract：:Lifespan is a trait of enormous personal interest. Research into the biological basis of human lifespan, however, is hampered by the long time to death. Using a novel approach of regressing (272,081) parental lifespans beyond age 40 years on participant genotype in a new large data set (UK Biobank), we here show that ...

journal_title：Nature communications

authors： Joshi PK,Fischer K,Schraut KE,Campbell H,Esko T,Wilson JF

更新日期：2016-03-31 00:00:00

abstract：:Sunlight is the ultimate driver of biosynthesis but photochemical steps late in biosynthetic pathways are very rare. They appear to play a role in the formation of certain furanocembranoids isolated from Caribbean corals. One of these compounds, intricarene, has been suspected to arise from an intramolecular 1,3-dipol...

journal_title：Nature communications

authors： Stichnoth D,Kölle P,Kimbrough TJ,Riedle E,de Vivie-Riedle R,Trauner D

更新日期：2014-12-03 00:00:00

abstract：:The resting-state human brain networks underlie fundamental cognitive functions and consist of complex interactions among brain regions. However, the level of complexity of the resting-state networks has not been quantified, which has prevented comprehensive descriptions of the brain activity as an integrative system....

journal_title：Nature communications

authors： Watanabe T,Hirose S,Wada H,Imai Y,Machida T,Shirouzu I,Konishi S,Miyashita Y,Masuda N

更新日期：2013-01-01 00:00:00

abstract：:Nanocrystal quantum dots are attractive materials for applications as nanoscale light sources. One impediment to these applications is fluctuations of single-dot emission intensity, known as blinking. Recent progress in colloidal synthesis has produced nonblinking nanocrystals; however, the physics underlying blinking...

journal_title：Nature communications

authors： Galland C,Ghosh Y,Steinbrück A,Hollingsworth JA,Htoon H,Klimov VI

更新日期：2012-06-19 00:00:00

abstract：:In most applications of nanoporous materials the pore structure is as important as the chemical composition as a determinant of performance. For example, one can alter performance in applications like carbon capture or methane storage by orders of magnitude by only modifying the pore structure. For these applications ...

journal_title：Nature communications

authors： Lee Y,Barthel SD,Dłotko P,Moosavi SM,Hess K,Smit B

更新日期：2017-05-23 00:00:00

abstract：:In the original version of this Article, the affiliation details for Antoine Aze, Michalis Fragkos, Stéphane Bocquet, Julien Cau and Marcel Méchali incorrectly omitted 'CNRS and the University of Montpellier'. This has now been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Aze A,Fragkos M,Bocquet S,Cau J,Méchali M

更新日期：2018-02-05 00:00:00

abstract：:In nature, plant tendrils can produce two fundamental motion modes, bending and chiral twisting (helical curling) distortions, under the stimuli of sunlight, humidity, wetting or other atmospheric conditions. To date, many artificial plant-like mechanical machines have been developed. Although some previously reported...

journal_title：Nature communications

authors： Wang M,Lin BP,Yang H

更新日期：2016-12-22 00:00:00

abstract：:The long external filament of bacterial flagella is composed of several thousand copies of a single protein, flagellin. Here, we explore the role played by lysine methylation of flagellin in Salmonella, which requires the methylase FliB. We show that both flagellins of Salmonella enterica serovar Typhimurium, FliC and...

journal_title：Nature communications

authors： Horstmann JA,Lunelli M,Cazzola H,Heidemann J,Kühne C,Steffen P,Szefs S,Rossi C,Lokareddy RK,Wang C,Lemaire L,Hughes KT,Uetrecht C,Schlüter H,Grassl GA,Stradal TEB,Rossez Y,Kolbe M,Erhardt M

更新日期：2020-04-24 00:00:00

abstract：:Striatum processes a wide range of functions including goal-directed behavior and habit formation, respectively encoded by the dorsomedial striatum (DMS) and dorsolateral striatum (DLS). GABAergic feedforward inhibition is known to control the integration of cortical information by striatal projection neurons (SPNs). ...

journal_title：Nature communications

authors： Fino E,Vandecasteele M,Perez S,Saudou F,Venance L

更新日期：2018-08-21 00:00:00

abstract：:Most DNA in the genomes of higher organisms does not encode proteins, yet much is transcribed by RNA polymerase II (RNAPII) into long non-coding RNAs (lncRNAs). The biological significance of most lncRNAs is largely unclear. Here, we identify a lncRNA (SVALKA) in a cold-sensitive region of the Arabidopsis genome. Muta...

journal_title：Nature communications

authors： Kindgren P,Ard R,Ivanov M,Marquardt S

更新日期：2018-11-01 00:00:00

abstract：:Chronic nonalcoholic steatohepatitis (NASH) is a metabolic disorder that often leads to liver fibrosis, a condition with limited therapy options. Adiponectin is an adipocytokine that regulates glucose and lipid metabolism via binding to its receptors AdipoR1 and AdipoR2, and AdipoRs signaling is reported to enhance fa...

journal_title：Nature communications

authors： Xu H,Zhao Q,Song N,Yan Z,Lin R,Wu S,Jiang L,Hong S,Xie J,Zhou H,Wang R,Jiang X

更新日期：2020-11-16 00:00:00

abstract：:The yeast Saccharomyces cerevisiae has been an essential component of human civilization because of its long global history of use in food and beverage fermentation. However, the diversity and evolutionary history of the domesticated populations of the yeast remain elusive. We show here that China/Far East Asia is lik...

journal_title：Nature communications

authors： Duan SF,Han PJ,Wang QM,Liu WQ,Shi JY,Li K,Zhang XL,Bai FY

更新日期：2018-07-12 00:00:00

abstract：:In two-dimensional interfacial assemblies, there is an interplay between molecular ordering and interface geometry, which determines the final morphology and order of entire systems. Here we present the interfacial phenomenon of spontaneous facet formation in a water droplet driven by designed peptide assembly. The id...

journal_title：Nature communications

authors： Jang HS,Lee JH,Park YS,Kim YO,Park J,Yang TY,Jin K,Lee J,Park S,You JM,Jeong KW,Shin A,Oh IS,Kwon MK,Kim YI,Cho HH,Han HN,Kim Y,Chang YH,Paik SR,Nam KT,Lee YS

更新日期：2014-04-11 00:00:00

abstract：:Enlarged vestibular aqueduct (EVA) is one of the most commonly identified inner ear malformations in hearing loss patients including Pendred syndrome. While biallelic mutations of the SLC26A4 gene, encoding pendrin, causes non-syndromic hearing loss with EVA or Pendred syndrome, a considerable number of patients appea...

journal_title：Nature communications

authors： Li M,Nishio SY,Naruse C,Riddell M,Sapski S,Katsuno T,Hikita T,Mizapourshafiyi F,Smith FM,Cooper LT,Lee MG,Asano M,Boettger T,Krueger M,Wietelmann A,Graumann J,Day BW,Boyd AW,Offermanns S,Kitajiri SI,Usami SI,Nak

更新日期：2020-03-12 00:00:00

abstract：:Angiogenesis is a necessary process for solid tumor growth. Cellular markers for endothelial cell proliferation are potential targets for identifying the vasculature of tumors in homeostasis. Here we customize the behaviors of engineered cells to recognize Apj, a surface marker of the neovascular endothelium, using sy...

journal_title：Nature communications

authors： Wang Z,Wang F,Zhong J,Zhu T,Zheng Y,Zhao T,Xie Q,Ma F,Li R,Tang Q,Xu F,Tian X,Zhu J

更新日期：2020-05-01 00:00:00

abstract：:Sodium-ion batteries are an alternative to lithium-ion batteries for large-scale applications. However, low capacity and poor rate capability of existing anodes are the main bottlenecks to future developments. Here we report a uniform coating of antimony sulphide (stibnite) on graphene, fabricated by a solution-based ...

journal_title：Nature communications

authors： Yu DY,Prikhodchenko PV,Mason CW,Batabyal SK,Gun J,Sladkevich S,Medvedev AG,Lev O

更新日期：2013-01-01 00:00:00

abstract：:Semiconductur nano- and micropillars represent a promising platform for hybrid nanodevices. Their ability to couple to a broad variety of nanomechanical, acoustic, charge, spin, excitonic, polaritonic, or electromagnetic excitations is utilized in fields as diverse as force sensing or optoelectronics. In order to full...

journal_title：Nature communications

authors： Doster J,Hoenl S,Lorenz H,Paulitschke P,Weig EM

更新日期：2019-11-20 00:00:00

abstract：:Practice improves perception and enhances neural representations of trained visual stimuli, a phenomenon known as visual perceptual learning (VPL). While attention to task-relevant stimuli plays an important role in such learning, Pavlovian stimulus-reinforcer associations are sufficient to drive VPL, even subconsciou...

journal_title：Nature communications

authors： Arsenault JT,Vanduffel W

更新日期：2019-08-09 00:00:00

abstract：:Understanding the impact of rare variants is essential to understanding human health. We analyze rare (MAF < 0.1%) variants against 4264 phenotypes in 49,960 exome-sequenced individuals from the UK Biobank and 1934 phenotypes (1821 overlapping with UK Biobank) in 21,866 members of the Healthy Nevada Project (HNP) coho...

journal_title：Nature communications

authors： Cirulli ET,White S,Read RW,Elhanan G,Metcalf WJ,Tanudjaja F,Fath DM,Sandoval E,Isaksson M,Schlauch KA,Grzymski JJ,Lu JT,Washington NL

更新日期：2020-01-28 00:00:00