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Regenerated cellulose/wool blend enhanced biomimetic hydroxyapatite mineralization.

Abstract：

:The current article investigates the effect of bioactive cellulose/wool blend on calcium phosphate biomimetic mineralization. Regenerated cellulose/wool blend was prepared by dissolution-regeneration of neat cellulose and natural wool in 1-butyl-3-methyl imidazolium chloride [Bmim][Cl], as a solvent for the two polymers. Crystalline hydroxyapatite nanofibers with a uniform size, shape and dimension were formed after immersing the bioactive blend in simulated body fluid. The cytotoxicity of cellulose/wool/hydroxyapatite was studied using animal fibroblast baby hamster kidney cells (BHK-21) and the result displayed good cytocompatability. This research work presents a green processing method for the development of novel cellulose/wool/hydroxyapatite hybrid materials for tissue engineering applications.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Salama A,El-Sakhawy M

doi

10.1016/j.ijbiomac.2016.07.077

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

920-925

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(16)30964-3

journal_volume

92

pub_type

杂志文章

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