Live-cell visualization of excitation energy dynamics in chloroplast thylakoid structures.

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Winkowski M,Stacewicz T

更新日期：2020-01-14 00:00:00

abstract：:Cosolvent Molecular Dynamics (MD) simulations are increasingly popular techniques developed for prediction and characterization of allosteric and cryptic binding sites, which can be rendered "druggable" by small molecule ligands. Despite their conceptual simplicity and effectiveness, the analysis of cosolvent MD traje...

journal_title：Scientific reports

authors： Sabanés Zariquiey F,de Souza JV,Bronowska AK

更新日期：2019-12-13 00:00:00

abstract：:Newly synthesized mitochondrial precursor proteins have to become unfolded to cross the mitochondrial membranes. This unfolding is achieved primarily by mitochondrial Hsp70 (mtHsp70) for presequence-containing precursor proteins. However, the membrane potential across the inner membrane (ΔΨ) could also contribute to u...

journal_title：Scientific reports

authors： Sato TK,Kawano S,Endo T

更新日期：2019-05-21 00:00:00

abstract：:Deregulated expression of microRNAs has been associated with angiogenesis. Studying the miRNome of locally advanced breast tumors we unsuspectedly found a dramatically repression of miR-204, a small non-coding RNA with no previous involvement in tumor angiogenesis. Downregulation of miR-204 was confirmed in an indepen...

journal_title：Scientific reports

authors： Flores-Pérez A,Marchat LA,Rodríguez-Cuevas S,Bautista-Piña V,Hidalgo-Miranda A,Ocampo EA,Martínez MS,Palma-Flores C,Fonseca-Sánchez MA,Astudillo-de la Vega H,Ruíz-García E,González-Barrios JA,Pérez-Plasencia C,Streber ML,Lópe

更新日期：2016-10-05 00:00:00

abstract：:Electrical power systems are one of the most important infrastructures that support our society. However, their vulnerabilities have raised great concern recently due to several large-scale blackouts around the world. In this paper, we investigate the robustness of power systems against cascading failures initiated by...

journal_title：Scientific reports

authors： Zhang Y,Yağan O

更新日期：2016-06-21 00:00:00

abstract：:This research investigated the association between prolonged disposable diaper (DD) wearing in infancy and primary enuresis (PNE). As a case-control study, we collected data from 376 children with enuresis and 379 healthy children who were sex- and age-matched at three tertiary care institutions in mainland China from...

journal_title：Scientific reports

authors： Li X,Wen JG,Shen T,Yang XQ,Peng SX,Wang XZ,Xie H,Wu XD,Du YK

更新日期：2020-09-01 00:00:00

abstract：:Activation of TLR4 by lipopolysaccharide (LPS) induces both pro-inflammatory and anti-inflammatory cytokine production in macrophages. Type 4 phosphodiesterases (PDE4) are key cAMP-hydrolyzing enzymes, and PDE4 inhibitors are considered as immunosuppressors to various inflammatory responses. We demonstrate here that P...

journal_title：Scientific reports

authors： Yang JX,Hsieh KC,Chen YL,Lee CK,Conti M,Chuang TH,Wu CP,Jin SC

更新日期：2017-04-06 00:00:00

abstract：:Rapid histopathological evaluation of fresh, unfixed human tissue using optical sectioning microscopy would have applications to intraoperative surgical margin assessment. Microscopy with ultraviolet surface excitation (MUSE) is a low-cost optical sectioning technique using ultraviolet illumination which limits fluore...

journal_title：Scientific reports

authors： Yoshitake T,Giacomelli MG,Quintana LM,Vardeh H,Cahill LC,Faulkner-Jones BE,Connolly JL,Do D,Fujimoto JG

更新日期：2018-03-14 00:00:00

abstract：:Plant-based proteins are increasingly being used in aquafeeds, but one of the limitations is taurine deficiency that can be especially detrimental for carnivorous fish. In this study, taurine supplementation in high plant protein diets (low fish meal, 15%) was investigated on the growth performance and fillet organole...

journal_title：Scientific reports

authors： Kotzamanis Y,Tsironi T,Brezas A,Grigorakis K,Ilia V,Vatsos I,Romano N,van Eys J,Kumar V

更新日期：2020-07-23 00:00:00

abstract：:Metformin is used to treat type 2 diabetes. Metformin activates AMP-activated kinase (AMPK), which may contribute to the action of metformin. Metformin also shows anti-proliferation activity. However, the mechanism is remained unknown. We found that treatment of MCF-7 cells with metformin induced the demethylase activ...

journal_title：Scientific reports

authors： Tanaka Y,Konishi A,Obinata H,Tsuneoka M

更新日期：2019-12-10 00:00:00

abstract：:Meromictic lakes are useful biogeochemical models because of their stratified chemical gradients and separation of redox reactions down the water column. Perennially ice-covered meromictic lakes are particularly stable, with long term constancy in their density profiles. Here we sampled Lake A, a deep meromictic lake ...

journal_title：Scientific reports

authors： Comeau AM,Harding T,Galand PE,Vincent WF,Lovejoy C

更新日期：2012-01-01 00:00:00

abstract：:During viral infections, some viruses subvert the host proteins to promote the translation or RNA replication with their protease-mediated cleavage. Poly (A)-binding protein (PABP) is a target for several RNA viruses; however, the impact of duck hepatitis A virus (DHAV) on PABP remains unknown. In this study, we demon...

journal_title：Scientific reports

authors： Sun D,Wang M,Wen X,Cheng A,Jia R,Sun K,Yang Q,Wu Y,Zhu D,Chen S,Liu M,Zhao X,Chen X

更新日期：2017-11-24 00:00:00

abstract：:This paper describes two different electrochemical affinity biosensing approaches for the simple, fast and bisulfite and PCR-free quantification of 5-methylated cytosines (5-mC) in DNA using the anti-5-mC antibody as biorecognition element. One of the biosensing approaches used the anti-5-mC as capture bioreceptor and...

journal_title：Scientific reports

authors： Povedano E,Vargas E,Montiel VR,Torrente-Rodríguez RM,Pedrero M,Barderas R,Segundo-Acosta PS,Peláez-García A,Mendiola M,Hardisson D,Campuzano S,Pingarrón JM

更新日期：2018-04-23 00:00:00

abstract：:The CoCrMo matrix composites with nano-TiO2 particle (2 wt.%, 4 wt.% and 6 wt.%) were fabricated by using a powder metallurgy technique (P/M), and the nano-TiO2 content was optimized in matrix. The microstructures, mechanical and high-temperature tribological properties of the synthesized composites were systematicall...

journal_title：Scientific reports

authors： Cui G,Liu Y,Li S,Liu H,Gao G,Kou Z

更新日期：2020-04-22 00:00:00

abstract：:We study heat dissipation of a multi-wall carbon nanotube (MWCNT) device fabricated from two crossed nanotubes on a SiNx substrate under the influence of a constant (DC) electric bias. By monitoring the temperature of the substrate, we observe negligible Joule heating within the nanotube lattice itself and instead hea...

journal_title：Scientific reports

authors： Voskanian N,Olsson E,Cumings J

更新日期：2019-07-25 00:00:00

abstract：:Orexins are originally characterized as orexigenic hypothalamic neuropeptides in mammals. Subsequent studies found orexin to be expressed and perform pleiotropic functions in multiple tissues in mammals. In avian (non-mammalian) species, however, orexin seemed to not affect feeding behavior and its physiological roles...

journal_title：Scientific reports

authors： Greene ES,Zampiga M,Sirri F,Ohkubo T,Dridi S

更新日期：2020-11-05 00:00:00

abstract：:Superdirective antennas developed over the last century have received renewed interest in recent years from the development of metamaterials. These arrays of electromagnetic resonators (or meta-atoms) carrying short wavelength electro- and/or magneto-inductive waves support current distributions with very high spatial...

journal_title：Scientific reports

authors： Vallecchi A,Radkovskaya A,Li L,Faulkner G,Stevens CJ,Shamonina E

更新日期：2020-01-14 00:00:00

abstract：:The human pathogen Legionella pneumophila delivers a large array of the effector proteins into host cells using the Dot/Icm type IVB secretion system. Among the proteins composing the Dot/Icm system, an inner membrane protein DotI is known to be crucial for the secretion function but its structure and role in type IV ...

journal_title：Scientific reports

authors： Kuroda T,Kubori T,Thanh Bui X,Hyakutake A,Uchida Y,Imada K,Nagai H

更新日期：2015-06-03 00:00:00

abstract：:Our purpose was to examine the effect of model, puffing topography (voltage, air-flow, puff interval), and method of collection on 19 elements/metals in aerosols from six tank-style electronic cigarettes (EC). Aerosols were collected from six brands using a cold trap or impinger and various puffing topographies. 19 el...

journal_title：Scientific reports

authors： Williams M,Li J,Talbot P

更新日期：2019-09-27 00:00:00

abstract：:Dissolved organic carbon (DOC) concentrations and water colour are increasing in many inland waters across northern Europe and northeastern North America. This inland-water "browning" has profound physical, chemical and biological repercussions for aquatic ecosystems affecting water quality, biological community struc...

journal_title：Scientific reports

authors： Meyer-Jacob C,Michelutti N,Paterson AM,Cumming BF,Keller WB,Smol JP

更新日期：2019-11-13 00:00:00

abstract：:New techniques for the field detection of inorganic improvised explosive devices (IEDs) are urgently developed. Although ion mobility spectrometry (IMS) has been proved to be the most effective method for screening organic explosives, it still faces a major challenge to detect inorganic explosives owing to their low v...

journal_title：Scientific reports

authors： Peng L,Hua L,Wang W,Zhou Q,Li H

更新日期：2014-10-16 00:00:00

abstract：:Cytochrome P450 monooxygenases (P450s) are heme-thiolate proteins whose role as drug targets against pathogens, as well as in valuable chemical production and bioremediation, has been explored. In this study we performed comprehensive comparative analysis of P450s in 13 newly explored oomycete pathogens. Three hundred...

journal_title：Scientific reports

authors： Sello MM,Jafta N,Nelson DR,Chen W,Yu JH,Parvez M,Kgosiemang IKR,Monyaki R,Raselemane SC,Qhanya LB,Mthakathi NT,Sitheni Mashele S,Syed K

更新日期：2015-07-01 00:00:00

abstract：:An industrial waste, 1,2,3-trichloropropane (TCP), is toxic and extremely recalcitrant to biodegradation. To date, no natural TCP degraders able to mineralize TCP aerobically have been isolated. In this work, we engineered a biosafety Pseudomonas putida strain KT2440 for aerobic mineralization of TCP by implantation o...

journal_title：Scientific reports

authors： Gong T,Xu X,Che Y,Liu R,Gao W,Zhao F,Yu H,Liang J,Xu P,Song C,Yang C

更新日期：2017-08-01 00:00:00

abstract：:The high growth rate of Ulva seaweeds makes it a potential algal biomass resource. In particular, Ulva meridionalis grows up to fourfold a day. Here, we demonstrated strong carbon fixation by U. meridionalis using 13C stable isotope labelling and traced the 13C flux through sugar metabolites with isotope-ratio mass sp...

journal_title：Scientific reports

authors： Tsubaki S,Nishimura H,Imai T,Onda A,Hiraoka M

更新日期：2020-11-23 00:00:00

abstract：:By moving the alkoxy group on the spacer from position 5 to position 4 to add another protocol for the algorithm for intermolecular and intramolecular hydrogen bonding interactions, highly regioselectivity of noncovalent synthesis of the hydrazide-based cyclic hexamers was achieved: one out of thirteen possible isomer...

journal_title：Scientific reports

authors： Yang Y,Huang F,Chen CF,Xia M,Cai Q,Qian FJ,Xiang J

更新日期：2013-01-01 00:00:00

abstract：:Sorting nexin 27 (SNX27) recycles PSD-95, Dlg1, ZO-1 (PDZ) domain-interacting membrane proteins and is essential to sustain adequate brain functions. Here we define a fundamental SNX27 function in T lymphocytes controlling antigen-induced transcriptional activation and metabolic reprogramming. SNX27 limits the activat...

journal_title：Scientific reports

authors： Tello-Lafoz M,Rodríguez-Rodríguez C,Kinna G,Loo LS,Hong W,Collins BM,Teasdale RD,Mérida I

更新日期：2017-11-27 00:00:00

abstract：:Our study aimed to compare the ability of anthropometric obesity indices to predict MetS and to determine the sex-specific optimal cut-off values for MetS among Malaysian vegetarians. Body weight, height, waist circumference (WC), blood pressure (BP), fasting venous blood sample were collected from 273 vegetarians in ...

journal_title：Scientific reports

authors： Ching YK,Chin YS,Appukutty M,Gan WY,Chan YM

更新日期：2020-11-30 00:00:00

abstract：:Doxorubicin (Dox) is a highly effective anticancer drug but cause acute ventricular dysfunction, and also induce late-onset cardiomyopathy and heart failure. Despite extensive studies, the pathogenic sequelae leading to the progression of Dox-associated cardiomyopathy remains unknown. We assessed temporal changes in a...

journal_title：Scientific reports

authors： Abdullah CS,Alam S,Aishwarya R,Miriyala S,Bhuiyan MAN,Panchatcharam M,Pattillo CB,Orr AW,Sadoshima J,Hill JA,Bhuiyan MS

更新日期：2019-02-14 00:00:00

abstract：:It is well known that haem serves as the prosthetic group of various haemoproteins that function in oxygen transport, respiratory chain, and drug metabolism. However, much less is known about the functions of the catabolites of haem in mammalian cells. Haem is enzymatically degraded to iron, carbon monoxide (CO), and ...

journal_title：Scientific reports

authors： Takeda TA,Mu A,Tai TT,Kitajima S,Taketani S

更新日期：2015-05-20 00:00:00

abstract：:This paper studies the social acceptability and feasibility of a focused protection strategy against coronavirus disease 2019 (COVID-19). We propose a control scheme to develop herd immunity while satisfying the following two basic requirements for a viable policy option. The first requirement is social acceptability:...

journal_title：Scientific reports

authors： Akamatsu T,Nagae T,Osawa M,Satsukawa K,Sakai T,Mizutani D

更新日期：2021-01-21 00:00:00