Developmental programming of polycystic ovary syndrome (PCOS): prenatal androgens establish pancreatic islet α/β cell ratio and subsequent insulin secretion.

abstract：:Gait speed in laboratory settings (in-laboratory gait speed) is one of the important indicators associated with the decline in functional abilities in older adulthood. Recently, it has become possible to measure gait speed during daily living (daily gait speed) using accelerometers. However, the relationship between t...

journal_title：Scientific reports

authors： Takayanagi N,Sudo M,Yamashiro Y,Lee S,Kobayashi Y,Niki Y,Shimada H

更新日期：2019-03-05 00:00:00

abstract：:Polysialic acid (PSA) is a large negatively charged glycan mainly attached to the neural cell adhesion molecule (NCAM). Several studies have shown that it is important for correct formation of brain circuitries during development and for synaptic plasticity, learning and memory in the adult. PSA also plays a major rol...

journal_title：Scientific reports

authors： Saini V,Lutz D,Kataria H,Kaur G,Schachner M,Loers G

更新日期：2016-06-21 00:00:00

abstract：:Effects of elevated seawater temperatures on deep-water benthos has been poorly studied, despite reports of increased seawater temperature (up to 4 °C over 24 hrs) coinciding with mass mortality events of the sponge Geodia barretti at Tisler Reef, Norway. While the mechanisms driving these mortality events are unclear...

journal_title：Scientific reports

authors： Strand R,Whalan S,Webster NS,Kutti T,Fang JKH,Luter HM,Bannister RJ

更新日期：2017-05-22 00:00:00

abstract：:Increased filaggrin expression was found to be correlated with severity scores in chronic spontaneous urticaria (CSU); however, the role of filaggrin breakdown products (FBPs) in CSU has not been studied. We collected stratum corneum (SC) specimens from the volar forearms of 10 CSU patients, 10 AD patients, and 10 hea...

journal_title：Scientific reports

authors： Pham DL,Lim KM,Joo KM,Park HS,Leung DYM,Ye YM

更新日期：2017-05-02 00:00:00

abstract：:Carbon fiber-synthetic foam core sandwich composites are widely used for many structural applications due to their superior mechanical performance and low weight. Unfortunately these structures typically have very poor acoustic performance. There is increasingly growing demand in mitigating this noise issue in sandwic...

journal_title：Scientific reports

authors： Sargianis J,Kim HI,Suhr J

更新日期：2012-01-01 00:00:00

abstract：:If the components of a battery, including electrodes, separator, electrolyte and the current collectors can be designed as paints and applied sequentially to build a complete battery, on any arbitrary surface, it would have significant impact on the design, implementation and integration of energy storage devices. Her...

journal_title：Scientific reports

authors： Singh N,Galande C,Miranda A,Mathkar A,Gao W,Reddy AL,Vlad A,Ajayan PM

更新日期：2012-01-01 00:00:00

abstract：:The recombination is one of the most frequently identified drivers of double-stranded DNA viruses evolution. However, the recombination events in African swine fever virus (ASFV) genomes have been poorly annotated. We hypothesize that the genetic determinants of ASFV variability are potential hot-spots for recombinati...

journal_title：Scientific reports

authors： Nefedeva M,Titov I,Tsybanov S,Malogolovkin A

更新日期：2020-10-28 00:00:00

abstract：:Multi-domain voltage-gated ion channels appear to have evolved through sequential rounds of intragenic duplication from a primordial one-domain precursor. Whereas modularity within one-domain symmetrical channels is established, little is known about the roles of individual regions within more complex asymmetrical cha...

journal_title：Scientific reports

authors： Penny CJ,Rahman T,Sula A,Miles AJ,Wallace BA,Patel S

更新日期：2016-12-12 00:00:00

abstract：:This study contrasted the impact of Tai Chi Chuan and general aerobic exercise on brain plasticity in terms of an increased grey matter volume and functional connectivity during structural magnetic resonance imaging (sMRI) and resting-state functional magnetic resonance imaging (rs-fMRI), explored the advantages of Ta...

journal_title：Scientific reports

authors： Cui L,Yin H,Lyu S,Shen Q,Wang Y,Li X,Li J,Li Y,Zhu L

更新日期：2019-11-21 00:00:00

abstract：:Ctenodactylinae (gundis) is a clade of rodents that experienced, in Miocene time, their greatest diversification and widest distribution. They expanded from the Far East, their area of origin, to Africa, which they entered from what would become the Arabian Peninsula. Questions concerning the origin of African Ctenoda...

journal_title：Scientific reports

authors： López-Antoñanzas R,Knoll F,Maksoud S,Azar D

更新日期：2015-08-07 00:00:00

abstract：:Quercetin is a natural flavonoid, which has been shown to have anti hepatitis C virus (HCV) properties. However, the exact mechanisms whereby quercetin impacts the HCV life cycle are not fully understood. We assessed the effect of quercetin on different steps of the HCV life cycle in Huh-7.5 cells and primary human he...

journal_title：Scientific reports

authors： Rojas Á,Del Campo JA,Clement S,Lemasson M,García-Valdecasas M,Gil-Gómez A,Ranchal I,Bartosch B,Bautista JD,Rosenberg AR,Negro F,Romero-Gómez M

更新日期：2016-08-22 00:00:00

abstract：:The impact of statin therapy on plasma asymmetric dimethylarginine (ADMA) levels has not been conclusively studied. Therefore the aim of the meta-analysis was to assess the effect of statins on circulating ADMA levels. We searched selected databases (up to August 2014) to identify randomized controlled trials (RCTs) t...

journal_title：Scientific reports

authors： Serban C,Sahebkar A,Ursoniu S,Mikhailidis DP,Rizzo M,Lip GY,Kees Hovingh G,Kastelein JJ,Kalinowski L,Rysz J,Banach M

更新日期：2015-05-13 00:00:00

abstract：:Muscle specific receptor tyrosine kinase (MuSK) is an essential postsynaptic transmembrane molecule that mediates clustering of acetylcholine receptors (AChR). MUSK exon 10 is alternatively skipped in human, but not in mouse. Skipping of this exon disrupts a cysteine-rich region (Fz-CRD), which is essential for Wnt-me...

journal_title：Scientific reports

authors： Nasrin F,Rahman MA,Masuda A,Ohe K,Takeda J,Ohno K

更新日期：2014-10-30 00:00:00

abstract：:The quest to 'forward-engineer' and fabricate biological machines remains a grand challenge. Towards this end, we have fabricated locomotive "bio-bots" from hydrogels and cardiomyocytes using a 3D printer. The multi-material bio-bot consisted of a 'biological bimorph' cantilever structure as the actuator to power the ...

journal_title：Scientific reports

authors： Chan V,Park K,Collens MB,Kong H,Saif TA,Bashir R

更新日期：2012-01-01 00:00:00

abstract：:Bacterial pneumonia is a major cause of acute lung injury and acute respiratory distress syndrome, characterized by alveolar barrier disruption. NLRP3 is best known for its ability to form inflammasomes and to regulate IL-1β and IL-18 production in myeloid cells. Here we show that NLRP3 protects the integrity of the a...

journal_title：Scientific reports

authors： Kostadinova E,Chaput C,Gutbier B,Lippmann J,Sander LE,Mitchell TJ,Suttorp N,Witzenrath M,Opitz B

更新日期：2016-08-01 00:00:00

abstract：:Archaeologically defined Upper Palaeolithic (UP, 45,000-10,000 years ago) "cultures" are often used as proxies to designate fossil populations. While recent genomic studies have partly clarified the complex relationship between European UP "cultures" and past population dynamics, they leave open numerous questions reg...

journal_title：Scientific reports

authors： Mounier A,Heuzé Y,Samsel M,Vasilyev S,Klaric L,Villotte S

更新日期：2020-12-14 00:00:00

abstract：:Renewable natural resources, such as solar radiation, rainfall, wind, and geothermal heat, together with ecosystem services, provide the elementary supports for the sustainable development of human society. To improve regional sustainability, we studied the spatial distributions and quantities of renewable natural res...

journal_title：Scientific reports

authors： Wang C,Zhang S,Yan W,Wang R,Liu J,Wang Y

更新日期：2016-11-18 00:00:00

abstract：:Stabilization exercise (SE) is evident for the management of chronic non-specific low back pain (LBP). The optimal dose-response-relationship for the utmost treatment success is, thus, still unknown. The purpose is to systematically review the dose-response-relationship of stabilisation exercises on pain and disabilit...

journal_title：Scientific reports

authors： Mueller J,Niederer D

更新日期：2020-10-09 00:00:00

abstract：:Septic shock is associated with multiple injuries to organs and tissues. These events may induce the regenerative response of adult stem cells. However, little is known about how endogenous stem cells are modulated by sepsis. This study analyzed the circulation of hematopoietic stem cells (HSCs), endothelial progenito...

journal_title：Scientific reports

authors： Skirecki T,Mikaszewska-Sokolewicz M,Godlewska M,Dołęgowska B,Czubak J,Hoser G,Kawiak J,Zielińska-Borkowska U

更新日期：2019-03-01 00:00:00

abstract：:Polarization control using single plasmonic nanoantennas is of interest for subwavelength optical components in nano-optical circuits and metasurfaces. Here, we investigate the role of two mechanisms for polarization conversion by plasmonic antennas: Structural asymmetry and plasmon hybridization through strong coupli...

journal_title：Scientific reports

authors： Wiecha PR,Black LJ,Wang Y,Paillard V,Girard C,Muskens OL,Arbouet A

更新日期：2017-01-19 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Weckmann K,Diefenthäler P,Baeken MW,Yusifli K,Turck CW,Asara JM,Behl C,Hajieva P

更新日期：2018-08-10 00:00:00

abstract：:Mechanosensitive ion channels are pore-forming transmembrane proteins that allow ions to move down their electrochemical gradient in response to mechanical stimuli. They participate in many plant developmental processes including the maintenance of plastid shape, pollen tube growth, etc. Herein, a total of 11, 10, 6, ...

journal_title：Scientific reports

authors： Kaur A,Taneja M,Tyagi S,Sharma A,Singh K,Upadhyay SK

更新日期：2020-10-06 00:00:00

abstract：:Visualization of the surgically operated tissues is vital to improve surgical model animals including mouse. Urological surgeries for urethra include series of fine manipulations to treat the increasing number of birth defects such as hypospadias. Hence visualization of the urethral status is vital. Inappropriate uret...

journal_title：Scientific reports

authors： Hyuga T,Hashimoto D,Matsumaru D,Kumegawa S,Asamura S,Suzuki K,Katayama KI,Nakamura S,Nakai H,Yamada G

更新日期：2020-10-26 00:00:00

abstract：:CeTe3 is a unique platform to investigate the itinerant magnetism in a van der Waals (vdW) coupled metal. Despite chemical pressure being a promising route to boost quantum fluctuation in this system, a systematic study on the chemical pressure effect on Ce3+(4f1) states is absent. Here, we report on the successful gr...

journal_title：Scientific reports

authors： Okuma R,Ueta D,Kuniyoshi S,Fujisawa Y,Smith B,Hsu CH,Inagaki Y,Si W,Kawae T,Lin H,Chuang FC,Masuda T,Kobayashi R,Okada Y

更新日期：2020-09-17 00:00:00

abstract：:The combination of a solid-phase microextraction process with graphite furnace atomic absorption spectrometry provides a very sensitive determination method for determining chromium in waters. Freshly prepared ferrite particles are used to retain the chromium species, and then separated by a magnet without the need fo...

journal_title：Scientific reports

authors： López-García I,Marín-Hernández JJ,Hernández-Córdoba M

更新日期：2020-03-24 00:00:00

abstract：:Bed bugs have shown a recent and rapid global expansion that has been suggested to be caused by cheap air travel. How a small, flightless and anachoretic insect that hides within its host's sleeping area manages to travel long distances is not yet clear. Bed bugs are attracted to the odour of sleeping humans and we su...

journal_title：Scientific reports

authors： Hentley WT,Webster B,Evison SEF,Siva-Jothy MT

更新日期：2017-09-28 00:00:00

abstract：:Transmembrane flux of Cs+ (a K+ congener) was measured in human red blood cells (RBCs; erythrocytes) on the 10-s time scale. This is the first report on dissolution dynamic nuclear polarization (dDNP) nuclear magnetic resonance (NMR) spectroscopy with this nuclide in mammalian cells. Four technical developments regula...

journal_title：Scientific reports

authors： Kuchel PW,Karlsson M,Lerche MH,Shishmarev D,Ardenkjaer-Larsen JH

更新日期：2019-12-23 00:00:00

abstract：:Modern flow cytometry instruments have become vital tools for high-throughput analysis of single cells. However, as issues with the cellular labeling techniques often used in flow cytometry have become more of a concern, the development of label-free modalities for cellular analysis is increasingly desired. Non-linear...

journal_title：Scientific reports

authors： Collier BB,Awasthi S,Lieu DK,Chan JW

更新日期：2015-05-29 00:00:00

abstract：:We introduce a new chemical space for drugs and drug-like molecules, exclusively based on their in silico ADME behaviour. This ADME-Space is based on self-organizing map (SOM) applied to 26,000 molecules. Twenty accurate QSPR models, describing important ADME properties, were developed and, successively, used as new m...

journal_title：Scientific reports

authors： Bocci G,Carosati E,Vayer P,Arrault A,Lozano S,Cruciani G

更新日期：2017-07-25 00:00:00

abstract：:We aimed to evaluate the association of plasma biomarkers linked to inflammation (bacterial translocation, inflammatory response, and endothelial dysfunction), coagulopathy, and angiogenesis with the severity of liver cirrhosis (assessed by the Child-Pugh-Turcotte score, CTP) and Child-Pugh B cirrhosis (CTP 7-9) in pa...

journal_title：Scientific reports

authors： Salgüero S,Medrano LM,González-García J,Berenguer J,Montes ML,Diéz C,Garcia-Broncano P,Llop-Herrera E,Pérez-Latorre L,Bellóno JM,Jiménez-Sousa MÁ,Resino S

更新日期：2020-06-25 00:00:00