Evaluation of surgical procedures of mouse urethra by visualization and the formation of fistula.

abstract：:Histone lysine acetyltransferase (KAT)-catalyzed acetylation of lysine residues in histone tails plays a key role in regulating gene expression in eukaryotes. Here, we examined the role of lysine side chain length in the catalytic activity of human KATs by incorporating shorter and longer lysine analogs into synthetic...

journal_title：Scientific reports

authors： Proietti G,Wang Y,Rainone G,Mecinović J

更新日期：2020-08-03 00:00:00

abstract：:Bacterial microcompartments (BMCs) are promising natural protein structures for applications that require the segregation of certain metabolic functions or molecular species in a defined microenvironment. To understand how endogenous cargos are packaged inside the protein shell is key for using BMCs as nano-scale reac...

journal_title：Scientific reports

authors： Liu Y,He X,Lim W,Mueller J,Lawrie J,Kramer L,Guo J,Niu W

更新日期：2018-10-10 00:00:00

abstract：:The recent discovery that human noroviruses (huNoVs) recognize sialic acids (SAs) in addition to histo-blood group antigens (HBGAs) pointed to a new direction in studying virus-host interactions during calicivirus infection. HuNoVs remain difficult to study due to the lack of an effective cell culture model. In this s...

journal_title：Scientific reports

authors： Tan M,Wei C,Huang P,Fan Q,Quigley C,Xia M,Fang H,Zhang X,Zhong W,Klassen JS,Jiang X

更新日期：2015-07-06 00:00:00

abstract：:The present work assessed the effects of dietary ratios of essential fatty acids, arachidonic (ARA), eicosapentaenoic (EPA) and docosahexaenoic acid (DHA), on liver and intestine oxidative status, intestinal histomorphology and gut microbiota of gilthead sea bream. Four isoproteic and isolipidic plant-based diets were...

journal_title：Scientific reports

authors： Magalhães R,Guerreiro I,Santos RA,Coutinho F,Couto A,Serra CR,Olsen RE,Peres H,Oliva-Teles A

更新日期：2020-08-14 00:00:00

abstract：:Endothelial dysfunction, which is caused by endothelial nitric oxide synthase (eNOS) uncoupling, is an initial step in atherosclerosis. This study was designed to explore whether Chinese medicine xin-mai-jia (XMJ) recouples eNOS to exert anti-atherosclerotic effects. Pretreatment of XMJ (25, 50, 100 μg/ml) for 30 minu...

journal_title：Scientific reports

authors： Yin YL,Zhu ML,Wan J,Zhang C,Pan GP,Lu JX,Ping S,Chen Y,Zhao FR,Yu HY,Guo T,Jian X,Liu LY,Zhang JN,Wan GR,Wang SX,Li P

更新日期：2017-03-02 00:00:00

abstract：:Low haemocompatibility of left ventricular assist devices (LVAD) surfaces necessitates anticoagulative therapy. Endothelial cell (EC) seeding can support haemocompatibility, however, the availability of autologous ECs is limited. In contrast, allogeneic ECs are readily available in sufficient quantity, but HLA dispari...

journal_title：Scientific reports

authors： Figueiredo C,Eicke D,Yuzefovych Y,Avsar M,Hanke JS,Pflaum M,Schmitto JD,Blasczyk R,Haverich A,Wiegmann B

更新日期：2019-08-05 00:00:00

abstract：:Mixtures of B4C, α-AlB12 and B powders were reactively spark plasma sintered at 1800 °C. Crystalline and amorphous boron powders were used. Samples were tested for their impact behavior by the Split Hopkinson Pressure Bar method. When the ratio R = B4C/α-AlB12 ≥ 1.3 for a constant B-amount, the major phase in the samp...

journal_title：Scientific reports

authors： Vasylkiv O,Borodianska H,Demirskyi D,Li P,Suzuki TS,Grigoroscuta MA,Pasuk I,Kuncser A,Badica P

更新日期：2019-12-20 00:00:00

abstract：:Although hepatitis B virus (HBV) infection is the leading cause of liver fibrosis (LF), the mechanisms underlying liver fibrotic progression remain unclear. Here, we investigated the gene expression profiles of HBV-related LF patients. Whole genome expression arrays were used to detect gene expression in liver biopsy ...

journal_title：Scientific reports

authors： Wang M,Gong Q,Zhang J,Chen L,Zhang Z,Lu L,Yu D,Han Y,Zhang D,Chen P,Zhang X,Yuan Z,Huang J,Zhang X

更新日期：2017-03-06 00:00:00

abstract：:The prediction of drug-target interactions is a key step in the drug discovery process, which serves to identify new drugs or novel targets for existing drugs. However, experimental methods for predicting drug-target interactions are expensive and time-consuming. Therefore, the in silico prediction of drug-target inte...

journal_title：Scientific reports

authors： Kuang Q,Xu X,Li R,Dong Y,Li Y,Huang Z,Li Y,Li M

更新日期：2015-09-09 00:00:00

abstract：:The intrinsic atomic mechanisms responsible for electronic doping of epitaxial graphene Moirés on transition metal surfaces is still an open issue. To better understand this process we have carried out a first-principles full characterization of the most representative Moiré superstructures observed on the Gr/Pt(111) ...

journal_title：Scientific reports

authors： Martínez JI,Merino P,Pinardi AL,Gonzalo OI,López MF,Méndez J,Martín-Gago JA

更新日期：2016-02-08 00:00:00

abstract：:Weathered granite of ion-adsorption rare earth elements (REEs) ore collected at Jiangxi Province, China was investigated to identify the minerals abundant in REEs. The analyses of scanning electron microscopy (SEM)-energy dispersive spectrometry (EDS) and laser ablation inductively coupled plasma mass spectrometry (LA...

journal_title：Scientific reports

authors： Mukai H,Kon Y,Sanematsu K,Takahashi Y,Ito M

更新日期：2020-11-19 00:00:00

abstract：:Inflammatory and cardiovascular biomarkers have been associated with obesity, but little is known about how they change upon dietary intervention and concomitant weight loss. Further, protein biomarkers might be useful for predicting weight loss in overweight and obese individuals. We performed secondary analyses in t...

journal_title：Scientific reports

authors： Figarska SM,Rigdon J,Ganna A,Elmståhl S,Lind L,Gardner CD,Ingelsson E

更新日期：2020-05-13 00:00:00

abstract：:Hierarchical classification (HC) stratifies and classifies data from broad classes into more specific classes. Unlike commonly used data classification strategies, this enables the probabilistic prediction of unknown classes at different levels, minimizing the burden of incomplete databases. Despite these advantages, ...

journal_title：Scientific reports

authors： Galea D,Inglese P,Cammack L,Strittmatter N,Rebec M,Mirnezami R,Laponogov I,Kinross J,Nicholson J,Takats Z,Veselkov KA

更新日期：2017-11-03 00:00:00

abstract：:The epidermis of snakes efficiently protects against dehydration and mechanical stress. However, only few proteins of the epidermal barrier to the environment have so far been identified in snakes. Here, we determined the organization of the Epidermal Differentiation Complex (EDC), a cluster of genes encoding protein ...

journal_title：Scientific reports

authors： Holthaus KB,Mlitz V,Strasser B,Tschachler E,Alibardi L,Eckhart L

更新日期：2017-03-27 00:00:00

abstract：:We report on measurements of the switching current distributions on two-dimensional superconducting NbTiN strips that are 5 nm thick and 80 nm wide. We observe that the width of the switching current distributions has a non-monotonous temperature dependence, where it is constant at the lowest temperatures up to about ...

journal_title：Scientific reports

authors： Ejrnaes M,Salvoni D,Parlato L,Massarotti D,Caruso R,Tafuri F,Yang XY,You LX,Wang Z,Pepe GP,Cristiano R

更新日期：2019-05-29 00:00:00

abstract：:Linearly polarized microwave radiation is shown to have its plane of polarization converted to the orthogonal state upon reflection from an ultrathin (λ/25) cavity array. The structure benefits from an uncomplicated design consisting of a metallic grating closely separated from a ground plane by a dielectric spacer. A...

journal_title：Scientific reports

authors： Tremain B,Rance HJ,Hibbins AP,Sambles JR

更新日期：2015-03-23 00:00:00

abstract：:Plant extracts contain many active compounds, which are tremendously fruitful for plant defence against several insect pests. The prime objectives of the present study were to calculate the extraction yield and to evaluate the leaf extracts of Citrullus colocynthis (L.), Cannabis indica (L.) and Artemisia argyi (L.) a...

journal_title：Scientific reports

authors： Ahmed M,Peiwen Q,Gu Z,Liu Y,Sikandar A,Hussain D,Javeed A,Shafi J,Iqbal MF,An R,Guo H,Du Y,Wang W,Zhang Y,Ji M

更新日期：2020-01-16 00:00:00

abstract：:Although lizards are often described as having robust neurogenic abilities, only a handful of the more than 6300 species have been explored. Here, we provide the first evidence of homeostatic neurogenesis in the leopard gecko (Eublepharis macularius). We focused our study on the medial cortex, homologue of the mammali...

journal_title：Scientific reports

authors： McDonald RP,Vickaryous MK

更新日期：2018-06-25 00:00:00

abstract：:Rab small GTPases play key roles in intracellular membrane trafficking. Rab33a promotes axon outgrowth of cultured rat hippocampal neurons by mediating the anterograde axonal transport of Golgi-derived vesicles and the concomitant exocytosis of these vesicles at the growth cone. However, the functions of Rab33 in vivo...

journal_title：Scientific reports

authors： Huang L,Urasaki A,Inagaki N

更新日期：2019-02-12 00:00:00

abstract：:In this decade coherent X-ray diffraction imaging has been demonstrated to reveal internal structures of whole biological cells and organelles. However, the spatial resolution is limited to several tens of nanometers due to the poor scattering power of biological samples. The challenge is to recover correct phase info...

journal_title：Scientific reports

authors： Takayama Y,Maki-Yonekura S,Oroguchi T,Nakasako M,Yonekura K

更新日期：2015-01-28 00:00:00

abstract：:This paper describes a Functional Electrical Stimulation (FES) standing system for rehabilitation of bone mineral density (BMD) in people with Spinal Cord Injury (SCI). BMD recovery offers an increased quality of life for people with SCI by reducing their risk of fractures. The standing system developed comprises an i...

journal_title：Scientific reports

authors： Zoulias ID,Armengol M,Poulton A,Andrews B,Gibbons R,Harwin WS,Holderbaum W

更新日期：2019-09-10 00:00:00

abstract：:Leptin has a central role in the maintenance of energy homeostasis, and its sensitivity is influenced by both the photoperiod and dietary polyphenols. The aim of this study was to investigate the effect of seasonal consumption of polyphenol-rich fruits on the hypothalamic leptin signaling system in non-obese and obese...

journal_title：Scientific reports

authors： Ibars M,Aragonès G,Ardid-Ruiz A,Gibert-Ramos A,Arola-Arnal A,Suárez M,Bladé C

更新日期：2018-09-11 00:00:00

abstract：:Rats are effective model animals and have contributed to the development of human medicine and basic research. However, the application of reproductive engineering techniques to rats is not as advanced compared with mice, and genome editing in rats has not been achieved using embryos obtained by in vitro fertilization...

journal_title：Scientific reports

authors： Honda A,Tachibana R,Hamada K,Morita K,Mizuno N,Morita K,Asano M

更新日期：2019-08-09 00:00:00

abstract：:In this study, we propose a novel sensitive solid-based immunosensor developed on a plasmonic nanopaper platform for the detection of Escherichia coli (E. coli) bacteria. This plasmonic nanopaper that comprises of carboxylated bacterial cellulose (CBC) impregnated with gold nanoparticles (AuNP-CBC), employed as a quen...

journal_title：Scientific reports

authors： Heli B,Ajji A

更新日期：2020-09-01 00:00:00

abstract：:Carbon nanotubes exhibit mechanical properties ideally suited for reinforced structural composites and surface area and conductivity attractive for electrochemical capacitors. Here we demonstrate the multifunctional synergy between these properties in a composite material exhibiting simultaneous mechanical and energy ...

journal_title：Scientific reports

authors： Muralidharan N,Teblum E,Westover AS,Schauben D,Itzhak A,Muallem M,Nessim GD,Pint CL

更新日期：2018-12-05 00:00:00

abstract：:Legionnaires' disease (LD) is an atypical pneumonia caused by the inhalation of Legionella. The methods used for the diagnosis of LD are direct culture of respiratory samples and urinary antigen detection. However, the sensitivity of culture is low, and the urinary antigen test is specific only for L. pneumophila sg1....

journal_title：Scientific reports

authors： Quero S,Párraga-Niño N,Sabria M,Barrabeig I,Sala MR,Jané M,Mateu L,Sopena N,Pedro-Botet ML,Garcia-Nuñez M

更新日期：2019-01-24 00:00:00

abstract：:Optical fibers have been utilized in various fields owing to their superior guiding performance. However, the modification of optical properties and light manipulation in fibers are restricted by the limitation of the core and cladding materials. In addition, the spot size of the light is constrained by the diffractio...

journal_title：Scientific reports

authors： Kim M,Kim S

更新日期：2020-12-01 00:00:00

abstract：:Measurements of volcanic tephra fallout deposits provide useful information about the magnitude and intensity of explosive volcanic eruptions and potential for remobilization of deposits as dangerous volcanic flows. However, gathering information in the vicinity of erupting craters is extremely dangerous, and moreover...

journal_title：Scientific reports

authors： Tanaka HKM

更新日期：2020-09-09 00:00:00

abstract：:Chlorophyll derivatives are known to enhance vision in vertebrates. They are thought to bind visual pigments (i.e., opsins apoproteins bound to retinal chromophores) directly within the retina. Consistent with previous findings in vertebrates, here we show that chlorin e6 - a chlorophyll derivative - enhances photopho...

journal_title：Scientific reports

authors： Degl'Innocenti A,Rossi L,Salvetti A,Marino A,Meloni G,Mazzolai B,Ciofani G

更新日期：2017-06-13 00:00:00

abstract：:Electrical stimulation is a common adjunct used to promote bone healing; its efficacy, however, remains uncertain. We conducted a meta-analysis of randomized sham-controlled trials to establish the efficacy of electrical stimulation for bone healing. We identified all trials randomizing patients to electrical or sham ...

journal_title：Scientific reports

authors： Aleem IS,Aleem I,Evaniew N,Busse JW,Yaszemski M,Agarwal A,Einhorn T,Bhandari M

更新日期：2016-08-19 00:00:00