Influence of external factors on hair cortisol concentrations.


:Measuring hair cortisol has attracted interest as a long term parameter for chronic stress evaluation. However, some studies support the hypothesis that locally produced cortisol, originating from the hair follicle or skin cells, affects concentrations in the hair. In an animal model the influence of different treatments (extensive brushing, administration of a hyperemising fluid that enhances blood circulation or a synthetic glucocorticoid) on the local cortisol production of hair was evaluated. Therefore eight sheep were sheared and the area of the skin surface of the back was quartered, with three quarters being daily subjected to a certain treatment and one quarter remaining untreated. The skin areas were sheared again after three weeks and cortisol concentrations of all wool samples were determined by immunoassay. Systemic cortisol concentrations were additionally monitored with faecal samples, indicating a significant decline in concentrations of glucocorticoid metabolites between week 1 and 2 or 3, respectively. We found no significant difference in hair cortisol concentrations between fields before treatment (p=0.310). Comparing matched fields before and after treatment, we found no significant differences in wool cortisol concentrations for fields treated with hyperemising fluid as well as for the control fields (p=0.329, p=0.097). Hairs exposed to either extensive brushing or dexamethasone fluid had significantly higher immunoreactive cortisol concentrations after three weeks of treatment (p=0.016, p=0.01). We therefore advise cautious interpretation when measuring hair cortisol concentrations as a parameter for chronic stress, because external factors may have a significant influence on the results.


Gen Comp Endocrinol


Salaberger T,Millard M,Makarem SE,Möstl E,Grünberger V,Krametter-Frötscher R,Wittek T,Palme R




Has Abstract


2016-07-01 00:00:00












  • Cloning and differential expression of steroid 5 alpha-reductase type 1 (Srd5a1) and type 2 (Srd5a2) from the Harderian glands of hamsters.

    abstract::In hamsters, the Harderian glands (HGs) exhibit a marked sexual dimorphism which is thought to depend on dihydrotestosterone (DHT); however, it is unclear whether hamster HGs contain one or more 5 alpha-reductases and whether these enzymes are differentially expressed in males and females. In this study, we isolated s...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Ramos L,Chávez B,Vilchis F

    更新日期:2010-04-01 00:00:00

  • Measuring fecal metabolites of endogenous steroids using ESI-MS/MS spectra in Taiwanese pangolin, (order Pholidota, family Manidae, Genus: Manis): A non-invasive method for endangered species.

    abstract::Pangolins are 'keystone species' driven towards extinction due to a lack of profound awareness and illegal trade. The drivers urge for immediate development in the understanding of demographics and reproductive dynamics of this species. In this study, we developed and validated a quantitative method to measure pangoli...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Arora B,Jai-Chyi Pei K,Feng Weng C,Ching-Min Sun N

    更新日期:2020-12-01 00:00:00

  • Maternal androgen levels during pregnancy are associated with early-life growth in Geoffroy's marmosets, Callithrix geoffroyi.

    abstract::Fetal development is a critical period of physical development, and factors in the intrauterine environment can cause lasting effects on the growth and development of offspring. There is little research evaluating organizational effects of early androgen exposure of endogenous maternal origins on the prenatal and post...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Smith AS,Birnie AK,French JA

    更新日期:2010-04-01 00:00:00

  • Isolation, synthesis, and biological activity of flounder [Asn1,Ile5,Thr9] angiotensin I.

    abstract::A novel angiotensin I (ANG I) has been isolated from incubates of plasma and kidney extracts of the flounder, Platichthys flesus, using ion-exchange, gel-permeation, and reverse-phase high performance liquid chromatography (HPLC). Its sequence was determined as H-Asn-Arg-Val-Tyr-Ile-His-Pro-Phe-Thr-Leu-OH by sequence ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Balment RJ,Warne JM,Takei Y

    更新日期:2003-01-01 00:00:00

  • Parathyroid hormone-related protein is a factor in normal fish pituitary.

    abstract::Using antibodies to the amino-terminal region of human parathyroid hormone-related protein (PTHrP) we have demonstrated PTHrP immunoreactivity in pituitaries and plasma of the sea bream (Sparus aurata). Pituitary cells at two distinct locations contained immunodetectable PTHrP; an anterior group in the rostral pars di...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Danks JA,Devlin AJ,Ho PM,Diefenbach-Jagger H,Power DM,Canario A,Martin TJ,Ingleton PM

    更新日期:1993-11-01 00:00:00

  • Catecholamine effects on blood pressure and heart rate in warm- and cold-acclimated American bullfrogs (Rana catesbeiana).

    abstract::The effects of epinephrine (E), norepinephrine (NE), phenylephrine (PHE), and isoproterenol (ISO) were studied in vivo on the blood pressure and heart rate of the conscious American bullfrog, Rana catesbeiana. Bullfrogs were chronically cannulated with a T cannula in the right sciatic artery. In warm-acclimated (22 de...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Herman CA,Mata PL

    更新日期:1985-09-01 00:00:00

  • Sex steroids stimulate leptin gene expression in Atlantic salmon parr hepatocytes in vitro.

    abstract::In mammals, leptin plays an important role in puberty and reproduction and leptin is regulated by sex steroids. Elevated leptin levels have been associated with sexual maturation in some teleosts such as Atlantic salmon. In the present study, primary cultures of Atlantic salmon hepatocytes were used to investigate the...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Trombley S,Rocha A,Schmitz M

    更新日期:2015-09-15 00:00:00

  • In vitro biosynthesis of steroids, including 11-deoxycortisol and 5 alpha-pregnane-3 beta,7 alpha,17,20 beta-tetrol, by ovaries of the goldfish Carassius auratus during the stage of oocyte final maturation.

    abstract::To examine the production of steroids with potential oocyte maturation-inducing or pheromonal activity in the goldfish (Carassius auratus) we have incubated mature ovaries of this species with 17-[3H]hydroxyprogesterone. The metabolites in the unconjugated, glucuronide, and sulfate fractions were identified by chromat...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Kime DE,Scott AP,Canario AV

    更新日期:1992-09-01 00:00:00

  • BDNF stimulates Ca2+ oscillation frequency in melanotrope cells of Xenopus laevis: contribution of IP3-receptor-mediated release of intracellular Ca2+ to gene expression.

    abstract::Pituitary melanotrope cells of the amphibian Xenopus laevis are neuroendocrine cells regulating the animal's skin color adaptation through secretion of α-melanophore-stimulating hormone (α-MSH). To fulfill this function optimally, the melanotrope cell undergoes plastic changes in structure and secretory activity in re...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Kuribara M,Eijsink VD,Roubos EW,Jenks BG,Scheenen WJ

    更新日期:2010-11-01 00:00:00

  • The role of arginine vasotocin and prostaglandin F2 alpha on oviposition and luteolysis in the common snapping turtle Chelydra serpentina.

    abstract::The administration of arginine vasotocin (AVT) to gravid snapping turtles with steroidogenically active corpora lutea and high plasma progesterone concentration (1480 +/- 155 pg/ml) did not trigger oviposition, whereas 12 days after ovulation when luteolysis occurred and plasma progesterone concentration was low (570 ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Mahmoud IY,Cyrus RV,McAsey ME,Cady C,Woller MJ

    更新日期:1988-01-01 00:00:00

  • Presence of immunoreactive melatonin in different tissues of the pigeon (Columba livia).

    abstract::The distribution of melatonin was studied at midday and midnight in pigeon plasma, pineal, hypothalamus, eyes, Harderian glands, and duodenum. Tissue samples were homogenized, extracted with chloroform, evaporated, and measured by our melatonin radioimmunoassay (RIA). All the extracts gave dilution curves parallel to ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Vakkuri O,Rintamäki H,Leppäluoto J

    更新日期:1985-04-01 00:00:00

  • Relationships between CB1 cannabinoid receptors and pituitary endocrine cells in Xenopus laevis: an immunohistochemical study.

    abstract::The distribution of the cannabinoid CB1 receptor and its relationships with individual endocrine cell types were investigated by immunohistochemistry in the anterior lobe of the Xenopus adenohypophysis. By use of a specific primary antibody raised in rabbit against the amino terminus of the rat CB1, we have found nume...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Cesa R,Guastalla A,Cottone E,Mackie K,Beltramo M,Franzoni MF

    更新日期:2002-01-01 00:00:00

  • Relative roles of theca and granulosa cells in ovarian follicular steroidogenesis in the amphibian, Rana nigromaculata.

    abstract::Using frog ovarian follicles in vitro we assessed the role of the theca/epithelium (THEP) layer and granulosa cells in the production of steroids. The THEP layer and granulosa cell-enclosed oocytes (GCEOs) were separated from ovarian follicles of the frog, Rana nigromaculata, by microdissection. Intact follicles (IFs)...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Kwon HB,Ahn RS

    更新日期:1994-05-01 00:00:00

  • Binding of dexamethasone by hepatic, intestine, and tailfin cytosol in Rana catesbeiana tadpoles during spontaneous and triiodothyronine-induced metamorphosis.

    abstract::The binding of the synthetic glucocorticoid dexamethasone (dex) to Rana catesbeiana tadpole liver, intestine, and tailfin cytosol during both spontaneous and triiodothyronine (T3)-induced metamorphosis has been examined. No change was observed in the dissociation constant (KD) in the liver or intestine during either s...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Woody CJ,Jaffe RC

    更新日期:1984-05-01 00:00:00

  • Specific cell surface binding sites shared by human Pro-IGF-I Eb-peptides and rainbow trout Pro-IGF-I Ea-4-peptide.

    abstract::Human pro-IGF-I Eb-peptide (hEb) and rainbow trout pro-IGF-I Ea-4-peptide (rtEa-4) have recently been shown to share unique biological activities [Gen. Comp. Endocrinol. 126 (2002) 342; Cell. Exp. Cell. Res. 280 (2002) 75]. To further understand the action mechanism of these proteins, we studied the binding properties...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Kuo YH,Chen TT

    更新日期:2003-06-15 00:00:00

  • Conserved transcriptional activity and ligand responsiveness of avian PPARs: Potential role in regulating lipid metabolism in mirgratory birds.

    abstract::Migratory birds undergo metabolic remodeling in tissues, including increased lipid storage in white adipose and fatty acid uptake and oxidation in skeletal muscle, to optimize energy substrate availability and utilization in preparation for long-distance flight. Different tissues undergo gene expression changes in kee...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Hamilton A,Ly J,Robinson JR,Corder KR,DeMoranville KJ,Schaeffer PJ,Huss JM

    更新日期:2018-11-01 00:00:00

  • Adaptive evolution of GPR39 in diverse directions in vertebrates.

    abstract::G protein-coupled receptors (GPCRs) play an important role in physiology and disease and represent productive drug targets. Orphan GPCRs, which have unknown endogenous ligands, are considered drug targets and consequently have attracted great interest in identifying their endogenous cognate ligands for deorphanization...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Zhang L,Song J,Zang Z,Tang H,Li W,Lai S,Deng C

    更新日期:2020-12-01 00:00:00

  • Effects of guanethidine administration on compensatory ovarian hypertrophy, compensatory ovulation and follicular development in the prepubertal female guinea pig.

    abstract::We analyzed the participation of sympathetic ovarian innervation in the prepubertal female guinea pig on regulation of compensatory ovarian hypertrophy (COH) and compensatory ovulation at puberty. The COH of the left ovary was significantly higher that of the right one (left ovary: 41.5+/-5.2 vs. 27.5+/-5.6%, p<0.05, ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Riboni L

    更新日期:2002-07-01 00:00:00

  • Estradiol and testosterone modulate the tissue-specific expression of ghrelin, ghs-r, goat and nucb2 in goldfish.

    abstract::Ghrelin, and nesfatin-1 (encoded by nucleobindin2/nucb2) are two metabolic peptides with multiple biological effects in vertebrates. While sex steroids are known to regulate endogenous ghrelin and NUCB2 in mammals, such actions by steroids in fish remain unknown. This study aimed to determine whether estradiol (E2) an...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Bertucci JI,Blanco AM,Canosa LF,Unniappan S

    更新日期:2016-03-01 00:00:00

  • Parathyroid hormone-related protein in teleost fish.

    abstract::A brief description is given of the discovery of PTHrP and the roles of the peptide in mammalian physiology. Next, the occurrence of PTHrP in the earliest vertebrates, sharks, skates and fishes, is reviewed and the calciotropic functions of PTHrP are addressed more specifically in fishes. Parathyroid hormone-related p...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审


    authors: Abbink W,Flik G

    更新日期:2007-06-01 00:00:00

  • Maternal programming of offspring hypothalamic-pituitary-interrenal axis in wild sockeye salmon (Oncorhynchus nerka).

    abstract::In fishes, maternal exposure to a stressor can influence offspring size and behavior. However, less is known about how maternal stress influences physiological processes in offspring, such as function of the hypothalamic-pituitary-interrenal (HPI) axis. We examined the impact of chronic maternal exposure to an acute c...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Sopinka NM,Jeffrey JD,Burnett NJ,Patterson DA,Gilmour KM,Hinch SG

    更新日期:2017-02-01 00:00:00

  • Changes in plasma levels of adrenaline, noradrenaline, glucose, lactate and CO2 in the green turtle, Chelonia mydas, during peak period of nesting.

    abstract::Plasma concentrations of stress hormones [adrenaline (ADR), noradrenaline (NR)], lactate, glucose and CO2 were monitored during peak nesting period (May-October) at different phases of nesting in the green turtle, Chelonia mydas. These include, emergence from sea, excavating body and nest chambers, oviposition, coveri...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Alkindi AY,Al-Habsi AA,Mahmoud IY

    更新日期:2008-02-01 00:00:00

  • Changes in plasma hormone levels correlate with fledging in nestling Leach's storm-petrels.

    abstract::Leach's storm-petrels accumulate large amounts of body mass throughout the nestling period. Approximately 4days before fledging, nestlings weigh 50-100% more than adults. In order to shed this excess mass, nestlings engage in behavioral anorexia, and leave the burrow when they are light enough to fly. During this pref...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Kozlowski CP,Mauck RA,O'Reilly KM,Philipsborn J,Ricklefs RE

    更新日期:2010-10-01 00:00:00

  • Catecholamine-mediated pressor responses to angiotensin II in the Pekin duck, Anas platyrhynchos.

    abstract::Asp1,Val5-angiotensin II (AII) caused dose-dependent increases in aortic blood pressure (BP) when injected into anesthetized Pekin ducks. Norepinephrine (NE) and epinephrine (E) concentrations in arterial plasma were found to be elevated 1 min after injection of AII, when BP was peaking, while plasma levels of unconju...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Wilson JX,Butler DG

    更新日期:1983-09-01 00:00:00

  • Effects of dietary arachidonic acid on the reproductive physiology of female Atlantic cod (Gadus morhua L.).

    abstract::The present study was designed to investigate potential effects of arachidonic acid (ARA) on the reproductive physiology of female Atlantic cod (Gadus morhua L.). Two-year old Atlantic cod of both sexes were equally distributed into eight sea cages after completion of their first spawning in May 2005. Four experimenta...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Norberg B,Kleppe L,Andersson E,Thorsen A,Rosenlund G,Hamre K

    更新日期:2017-09-01 00:00:00

  • Cloning of the gene and complete cDNA encoding a type 2 deiodinase from Fundulus heteroclitus.

    abstract::Recently, we reported the cloning of a cDNA fragment from Fundulus heteroclitus liver encoding the open reading frame of type 2 deiodinase (FhD2). We here report the cloning of 14 kb of genomic sequence from F. heteroclitus that includes the previously reported coding region of the F. heteroclitus Dio2 gene (FhDio2), ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Orozco A,Jeziorski MC,Linser PJ,Greenberg RM,Valverde-R C

    更新日期:2002-09-01 00:00:00

  • Docosahexaenoic acid induces PPARγ-dependent preadipocytes apoptosis in grass carp Ctenopharyngodon idella.

    abstract::Our previous study showed that docosahexaenoic acid (DHA) plays an important role in decreasing lipid accumulation by inducing apoptosis of the adipocytes in grass carp. However, the mechanism involved remains unclear. DHA has been reported as the natural ligand of PPARγ. The present study aimed to assess whether PPAR...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Jin A,Shi XC,Liu Y,Sun J,Ji H

    更新日期:2018-09-15 00:00:00

  • Cryosurvival of isolated testicular cells and testicular tissue of tench Tinca tinca and goldfish Carassius auratus following slow-rate freezing.

    abstract::Experiments were carried out to test the efficiency of cryopreservation of whole testicular tissue in tench Tinca tinca and goldfish Carassius auratus and compare it to cryopreservation of isolated testicular cells. Additionally, effects of three cryoprotectants (dimethyl sulphoxyde - Me2SO, methanol - MeOH and ethyle...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Marinović Z,Lujić J,Kása E,Bernáth G,Urbányi B,Horváth Á

    更新日期:2017-05-01 00:00:00

  • The dopaminergic system in the brain of the native Thai chicken, Gallus domesticus: localization and differential expression across the reproductive cycle.

    abstract::Dopamine (DA) has a pivotal role in avian prolactin (PRL) secretion, acting centrally through D(1) DA receptors to stimulate PRL secretion by operating through vasoactive intestinal peptide (VIP). DA also inhibits PRL secretion by activating D(2) DA receptors at the pituitary level. This study was designed to investig...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Sartsoongnoen N,Kosonsiriluk S,Prakobsaeng N,Songserm T,Rozenboim I,Halawani ME,Chaiseha Y

    更新日期:2008-10-01 00:00:00

  • Plasma progesterone through pregnancy and the estrous cycle in the eastern quoll, Dasyurus viverrinus.

    abstract::Plasma progesterone concentrations were measured every 2 or 3 days in eastern quoll, Dasyurus viverrinus, during pregnancy (20.5 +/- 0.8 days, n = 6, mean +/- SEM) and the estrous cycle (37.5 +/- 0.7 days, n = 20, mean +/- SEM). The pattern was not apparently different between the two reproductive states. There was a ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Hinds LA

    更新日期:1989-07-01 00:00:00