Abstract：
:The present study examined plasma concentrations of insulin-like growth factor (IGF)-I, IGF-II and IGF-binding proteins (IGFBPs) during posthatch growth and development in chickens. Three distinct proteins which bound 125I-IGF-I were observed irrespective of age or sex, these having apparent molecular weights of 22, 28, and 36 kDa. The major IGFBP present during much of the growth and development period was the 28-kDa form followed by the 36-kDa form. Plasma concentrations of IGF-II and of the 22-kDa IGFBP showed little ontogenic variation with the exception of elevated levels of the 22 kDa IGFBP in 1-day-old chicks. The circulating concentrations of IGF-I and of the 28-kDa IGFBP increased progressively between the time of hatching to reach a maximum at 6 weeks of age and subsequently declined to lower levels in adults. Somewhat similarly, the 36-kDa IGFBP increased during early pre- and posthatching growth to a maximum at 6 weeks of age. There were marked sex differences in circulating concentrations of IGF-I in young (4 week) and adult chickens and in the 36-kDa IGFBP in the adult, both being lower in females. Estrogen treatment of adult male chickens decreased the circulating concentrations of IGF-I together with the level of both the 28- and 36-kDa IGFBPs. Testosterone treatment had no effect on the circulating concentrations of either IGF-I or IGFBPs in adult female chickens. We conclude that the relative levels of IGF-I, IGF-II, and the IGFBPs change with age. In addition, circulating concentrations of estrogen may play a role in the regulation of IGF-I and IGFBPs.
journal_name
Gen Comp Endocrinoljournal_title
General and comparative endocrinologyauthors
Radecki SV,Capdevielle MC,Buonomo FC,Scanes CGdoi
10.1006/gcen.1997.6898subject
Has Abstractpub_date
1997-07-01 00:00:00pages
109-17issue
1eissn
0016-6480issn
1095-6840pii
S0016-6480(97)96898-2journal_volume
107pub_type
杂志文章abstract：:Hyperglycemia that is caused by the release of crustacean hyperglycemic hormone (CHH) from the sinus gland to hemolymph is one of the hallmark physiological phenomena, occurring in decapod crustaceans experiencing stressful conditions. However, the mechanism(s) by which such elevated glucose levels return to resting l...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2014.01.012
更新日期：2014-04-01 00:00:00
abstract：:In the genetic sex determination of vertebrates, the gonadal sex depends on the combination of sex chromosomes that a zygote possesses. Despite the discovery of the sex-determining gene (SRY/Sry) in mammals in 1990s, the sex-determining gene in non-mammalian vertebrates remained an enigma for over a decade. In most ma...
journal_title：General and comparative endocrinology
pub_type： 杂志文章,评审
doi：10.1016/j.ygcen.2015.10.004
更新日期：2016-12-01 00:00:00
abstract：:The copepod Calanus finmarchicus is the most abundant zooplankton species in the North Atlantic. While the life history of this crustacean is well studied, little is known about its peptidergic signaling systems despite the fact that these pathways are undoubtedly important components of its physiological/behavioral c...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2013.03.018
更新日期：2013-06-15 00:00:00
abstract：:Jawed vertebrates (Gnasthostomes) are broadly separated into cartilaginous fishes (Chondricthyes) and bony vertebrates (Osteichthyes). Cartilaginous fishes are divided into chimaeras (e.g. ratfish, rabbit fish and elephant shark) and elasmobranchs (e.g. sharks, rays and skates). Both cartilaginous fish and bony verteb...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2013.06.021
更新日期：2013-11-01 00:00:00
abstract：:Birds use both the corticosterone stress response and immune system to meet physiological challenges during exposure to adverse climatic conditions. To assess the stress level and immune response of the Asian Great Bustard during conditions of severe winter weather, we measured fecal corticosterone (CORT) and Immunogl...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2018.02.014
更新日期：2018-05-15 00:00:00
abstract：:The tegu lizard Salvator merianae is a large, widely distributed teiid lizard endemic to South America that exhibits annual cycles of high activity during the spring and summer, and hibernation during winter. This pattern of activity and hibernation is accompanied by profound seasonal changes in physiology and behavio...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2018.06.006
更新日期：2019-03-01 00:00:00
abstract：:Gonadotropin-releasing hormone (GnRH) of vertebrates is now believed to have multiple functions in addition to its role as a hypophysiotropic hormone, as originally defined. Recently, it has been shown that GnRH occurs also in the ascidians, which are considered ancestral chordates. Here the author shows that GnRH ind...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.2001.7728
更新日期：2001-12-01 00:00:00
abstract：:Vitamin D binding protein (DBP) was isolated from the plasma of the snapping turtle, Chelydra serpentina (mixed sex adult), and compared with the previously characterized dual function binding plasma protein that binds both thyroxine (T4) and vitamin D (tsTDBP) in an emydid turtle, Trachemys scripta. Purification of C...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1996.0182
更新日期：1996-12-01 00:00:00
abstract：:Progesterone, 4-androstenedione, testosterone, dihydrotestosterone, 5 alpha-androstane-3 alpha,17 beta-diol (3 alpha-diol), 5 alpha-androstane-3 beta, 17 beta-diol (3 beta-diol), estrone, and estradiol levels were determined by radioimmunoassay in the different lobules of the testis of Salamandra salamandra throughout...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(85)90337-5
更新日期：1985-05-01 00:00:00
abstract：:Explants of tail fin from tadpoles of Rana catesbeiana maintained in tissue culture underwent resorption when exposed to a medium containing 150 nM thyroxine (T4). Increases in the specific activity of hexosaminidase (Hex) and of acid phosphatase (AP) were associated with this response. Ovine prolactin inhibited resor...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(86)90025-0
更新日期：1986-10-01 00:00:00
abstract：:Vitellogenesis in tuatara (Sphenodon punctatus) on Stephens Island, New Zealand, at the southern (coolest) end of the geographical range of this species involves a prolonged period of about 3 years of the average 4-year reproductive cycle. These studies used a semiquantitative electrophoretic assay for vitellogenin (V...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1994.1117
更新日期：1994-08-01 00:00:00
abstract：:Aromatase is the key enzyme for estrogen biosynthesis and is encoded by Cyp19 gene. Placental cotyledons are the main site of Cyp19 gene expression during pregnancy. The present study was aimed to investigate if DNA methylation and thus epigenetic mechanisms play a potential role in stage-specific regulation of Cyp19 ...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2010.07.012
更新日期：2010-11-01 00:00:00
abstract：:The presence of specific, saturable, high-affinity gonadotropin receptors was demonstrated in membrane preparations from preovulatory ovarian follicles of amago salmon (Oncorhynchus rhodurus), including intact follicles, isolated thecal layers, and isolated granulosa cells. Optimum conditions for the binding study usi...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(88)90177-3
更新日期：1988-10-01 00:00:00
abstract：:The G-protein-coupled receptor 54 (muGPR54) cDNA was cloned from the brain of the grey mullet, and its expression level, as well as those of the gonadotropin-releasing hormones (GnRH1, GnRH2, GnRH3) and dopamine receptor D2 (drd2), in the brain, pituitary and ovary of pubertal fish (early, intermediate, advanced) were...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2006.09.008
更新日期：2007-01-15 00:00:00
abstract：:Phenotypic effects of global warming have been documented in many different taxa. However, the importance of transgenerational phenotypic plasticity in these adaptations are seldom studied. In birds, temperature could affect egg characteristics. Higher temperatures during egg-laying may reduce maintenance costs for fe...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2019.02.004
更新日期：2019-05-01 00:00:00
abstract：:The functional abilities of 9.5-, 10.5-, 11.5-, and 12.5-day-old chick embryos to respond to exogenous thyrotrophin-releasing hormone (TRH) were evaluated by means of changes in plasma total thyroxine (T4). T4 concentrations were determined 3.0, 6.0, 12.0, and 24.0 hr after TRH treatment. The data of the present inves...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(84)90112-6
更新日期：1984-08-01 00:00:00
abstract：:Plasma levels of testosterone and corticosterone were measured in free-living male bush warblers captured on their breeding ground at different times of the breeding season. Their territoriality was also estimated from their singing response to song playbacks. The pattern of change detected in the levels of plasma tes...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1999.7381
更新日期：1999-12-01 00:00:00
abstract：:The vertebrate oxytocin and vasopressin receptors form a family of G-protein-coupled receptors (GPCRs) that mediate a large variety of functions, including social behavior and the regulation of blood pressure, water balance and reproduction. In mammals four family members have been identified, three of which respond t...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2011.10.011
更新日期：2012-01-01 00:00:00
abstract：:Thyroid hormones (THs) are crucial for normal vertebrate development and are the one obligate morphogen that drives amphibian metamorphosis. However, contrary to other metamorphosing vertebrates, lampreys exhibit a sharp drop in serum TH early in metamorphosis, and anti-thyroid agents such as potassium perchlorate (KC...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2012.12.007
更新日期：2013-03-01 00:00:00
abstract：:The distribution of melatonin was studied at midday and midnight in pigeon plasma, pineal, hypothalamus, eyes, Harderian glands, and duodenum. Tissue samples were homogenized, extracted with chloroform, evaporated, and measured by our melatonin radioimmunoassay (RIA). All the extracts gave dilution curves parallel to ...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(85)90136-4
更新日期：1985-04-01 00:00:00
abstract：:Effects of fasting on the growth hormone (GH)--growth hormone receptor (GHR)-insulin-like growth factor-I (IGF-I) axis were characterized in seawater-acclimated tilapia (Oreochromis mossambicus). Fasting for 4 weeks resulted in significant reductions in body weight and specific growth rate. Plasma GH and pituitary GH ...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2006.04.007
更新日期：2006-09-15 00:00:00
abstract：:Glucagon plays a pivotal role in the regulation of metabolism. A glucagon receptor has been previously characterized in the frog, Rana tigrina rugulosa, and the frog and human glucagon receptors have been shown to possess similar binding affinities toward human glucagon. To study the structural evolution of glucagon p...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.2001.7697
更新日期：2001-11-01 00:00:00
abstract：:We investigated the effect of several potential carbohydrate secretagogues, amino acids, a ketoacid, and potassium chloride on insulin, glucagon, and somatostatin release from the in vitro perfused Brockmann body of channel catfish (Ictalurus punctatus). Mannose (15 mM) stimulated the release of insulin and somatostat...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(87)90120-1
更新日期：1987-03-01 00:00:00
abstract：:Dopamine (DA) was infused into the third ventricle of anesthetized laying turkey hens at various concentrations to determine its effect on both basal prolactin (PRL) levels and ongoing electrically induced PRL secretion. The infusion of DA at rates of 1.0 or 10.0 nmol/min resulted in dose dependent increases in plasma...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1995.1049
更新日期：1995-04-01 00:00:00
abstract：:Receptors for vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) in turkey cerebral cortex were characterized using two approaches: (1) in vitro radioreceptor binding of [125I]-VIP, and (2) effects of peptides from the PACAP/VIP/secretin family on cyclic AMP formation. T...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2004.03.007
更新日期：2004-06-01 00:00:00
abstract：:The role of ovarian hormones in the expression of parental behavior and in the regulation of LH secretion was investigated in incubating commercial meat-type hens. After ovariectomy, incubating hens continued to incubate eggs normally and brooded day-old chicks given to replace eggs, in a manner similar to sham-ovarie...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1996.0013
更新日期：1996-01-01 00:00:00
abstract：:Juvenile coho salmon, Oncorhynchus kisutch, were either immersed in thyroxin-containing water (T4; 20 micrograms/ml) or implanted with cortisol (5 mg), bovine growth hormone (GH; 1.5 microgram/g body wt), or ovine prolactin (PRL; 1.5 microgram/g body wt), both early and late in smoltification. T4 and cortisol treatmen...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(86)90007-9
更新日期：1986-11-01 00:00:00
abstract：:The zebrafish is a powerful genetic model organism. In recent years, zebrafish has been increasingly used to model human diseases. Due to a number of recent technological advancements, the genetic tool box is now also stocked with sophisticated transgenic and reverse genetic tools. Here, we focus on both commonly used...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2013.02.002
更新日期：2013-07-01 00:00:00
abstract：:Free-living starlings (Sturnus vulgaris) were caught by mist netting. Blood samples were taken from them between 20 sec and 4 min after capture and assayed for corticosterone. Before 1 min corticosterone levels were constant (10.3 nmol litre-1) but after 1 min they increased rapidly (27.0 +/- 3.6 nmol litre-1 min-1). ...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(83)90085-0
更新日期：1983-08-01 00:00:00
abstract：:The cell types within the endocrine pancreatic tissue and anterior intestine of larvae and juveniles of representatives of the two southern-hemisphere families (Mordaciidae and Geotriidae) were compared, using immunohistochemistry and antisera against insulin (lamprey, bovine), two somatostatins (SST-14, -34), two PP-...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1993.1152
更新日期：1993-11-01 00:00:00
