Contrast agent comparison for three-dimensional micro-CT angiography: A cadaveric study.

abstract：:Red blood cells (RBCs) loaded with iron oxide nanoparticles have been proposed as biomimetic constructs with long half-life (ca. 20 days) in the blood compartment and potentially interesting properties (such as relaxivity) as intravascular contrast agents for magnetic resonance imaging. However, the encapsulation of n...

journal_title：Contrast media & molecular imaging

authors： Boni A,Ceratti D,Antonelli A,Sfara C,Magnani M,Manuali E,Salamida S,Gozzi A,Bifone A

更新日期：2014-05-01 00:00:00

abstract：:Various contrast agents (Magnevist, Gadovist and Multihance) loaded into polymeric nanocapsules were synthesized by the inverse miniemulsion technique. The relaxivity of the resultant contrast agents was assessed at 1.5 T magnetic field strength. The ionic relaxivity of the contrast agents could at least be maintained...

journal_title：Contrast media & molecular imaging

authors： Sharma S,Paiphansiri U,Hombach V,Mailänder V,Zimmermann O,Landfester K,Rasche V

更新日期：2010-03-01 00:00:00

abstract：:Knowledge of the longitudinal and transverse relaxation times (T(1) and T(2)) of water protons in an aqueous solution of an MRI contrast agent is essential for its characterization. These parameters can be measured at low field on low resolution spectrometers or at high field on high resolution spectrometers. The reli...

journal_title：Contrast media & molecular imaging

authors： Henoumont C,Laurent S,Vander Elst L

更新日期：2009-11-01 00:00:00

abstract：:Carcinoma of the prostate is the most frequent diagnosed malignant tumor in men and is the second leading cause of cancer-related death in this group. The cure rate of prostate cancer is highly dependent on the stage of disease at the diagnosis and early detection is key to designing effective treatment strategies. Th...

journal_title：Contrast media & molecular imaging

authors： Abdolahi M,Shahbazi-Gahrouei D,Laurent S,Sermeus C,Firozian F,Allen BJ,Boutry S,Muller RN

更新日期：2013-03-01 00:00:00

abstract：:Inorganic doping was used to create flexible, paramagnetic nanoparticle contrast agents for in vivo molecular magnetic resonance imaging (MRI) with low transverse relaxivity (r2). Most nanoparticle contrast agents formed from superparamagnetic metal oxides are developed with high r2. While sensitive, they can have lim...

journal_title：Contrast media & molecular imaging

authors： Clavijo Jordan MV,Beeman SC,Baldelomar EJ,Bennett KM

更新日期：2014-09-01 00:00:00

abstract：:Generally angiogenic factors induce the expression of E-selectin in vascular endothelial cells in the tumors. In this study, we employed an anti-E-selectin monoclonal antibody to target tumors in vivo and evaluated an optical imaging reagent to visualize tumor regions. The anti-E-selectin antibody was conjugated on th...

journal_title：Contrast media & molecular imaging

authors： Hirai M,Hiramatsu Y,Iwashita S,Otani T,Chen L,Li YG,Okada M,Oie K,Igarashi K,Wakita H,Seno M

更新日期：2010-03-01 00:00:00

abstract：Objective:To synthesize 68Ga-Glu-urea-Lys(Ahx)-HBED-CC (68Ga-PSMA-11) with a synthesis module and investigate PET-CT imaging to monitor PSMA expression during prostate cancer (PCa) progression and tumor growth in mice bearing subcutaneous PCa xenografts. Method:The radiochemical purity and stability of  68Ga-PSMA-11 w...

journal_title：Contrast media & molecular imaging

authors： Wang Y,Shao G,Wu J,Cui C,Zang S,Qiu F,Jia R,Wang Z,Wang F

更新日期：2018-04-26 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this pilot study was to establish the ability of dynamic contrast enhanced computed tomography (DCE-CT) to detect changes in tumor blood flow (BF) and oxygenation induced by vasoactive substances in rats. MATERIALS AND METHODS:Under ultrasound guidance, a fiber-optic probe was g...

journal_title：Contrast media & molecular imaging

authors： Pollard RE,Larson RF

更新日期：2011-01-01 00:00:00

abstract：:We evaluated the difference in the status of dopamine transporters (DATs) depending on Parkinsonism, cerebellar, and autonomic features using F-18 FP-CIT positron emission tomography (PET) in multiple system atrophy with cerebellar ataxia (MSA-C). We also assessed whether the DAT PET could be useful in the management ...

journal_title：Contrast media & molecular imaging

authors： Jeong YJ,Cheon SM,Kang DY,Kim JW

更新日期：2017-11-29 00:00:00

abstract：PURPOSE:Regional wall thickening measurement by delayed contrast MRI may assess myocardial viability and functional recovery of ischemic cardiomyopathy. MATERIALS AND METHODS:Delayed contrast MRI data was used in 40 patients with significant coronary artery disease and severe left ventricular dysfunction. Regional wal...

journal_title：Contrast media & molecular imaging

authors： Sharma R,Katz JK

更新日期：2009-01-01 00:00:00

abstract：:Developing agents with 'seek, treat and see' capability is critical for personalized molecular medicine. Those agents will specifically target the disease markers for diagnosis and apply the biologically effective dose for treatment. Retinoids regulate a multitude of biological processes. In addition, retinoic acid ca...

journal_title：Contrast media & molecular imaging

authors： Wang W,Qiu X,Zhang F,Sun J,Cameron AG,Wendt JA,Mawad ME,Ke S

更新日期：2011-07-01 00:00:00

abstract：:A generic site-specific conjugation method that generates a homogeneous product is of utmost importance in tracer development for molecular imaging and therapy. We explored the protein-ligation capacity of the enzyme Sortase A to label camelid single-domain antibody-fragments, also known as nanobodies. The versatility...

journal_title：Contrast media & molecular imaging

authors： Massa S,Vikani N,Betti C,Ballet S,Vanderhaegen S,Steyaert J,Descamps B,Vanhove C,Bunschoten A,van Leeuwen FW,Hernot S,Caveliers V,Lahoutte T,Muyldermans S,Xavier C,Devoogdt N

更新日期：2016-09-01 00:00:00

abstract：Objective:To qualitatively and quantitatively compare the contrast-enhanced magnetic resonance angiography (MRA) and magnetic resonance imaging (MRI) in one-stop shop of abdominal imaging with Gadobutrol and Gd-DTPA at equimolar doses of gadolinium. Materials and Methods:This was a prospective designed, multiple cente...

journal_title：Contrast media & molecular imaging

authors： Liu X,Li Z,Zhang W,Yang C,Diao Y,Duan T,Fu Y,Ren J,Bin S

更新日期：2019-12-02 00:00:00

abstract：:A new high-throughput MRI method for screening chemical exchange saturation transfer (CEST) agents is demonstrated, allowing simultaneous testing of multiple samples with minimal attention to sample configuration and shimming of the main magnetic field (B(0)). This approach, which is applicable to diamagnetic, paramag...

journal_title：Contrast media & molecular imaging

authors： Liu G,Gilad AA,Bulte JW,van Zijl PC,McMahon MT

更新日期：2010-05-01 00:00:00

abstract：:Recent advances in artificial intelligence (AI) and deep learning (DL) have impacted many scientific fields including biomedical maging. Magnetic resonance imaging (MRI) is a well-established method in breast imaging with several indications including screening, staging, and therapy monitoring. The rapid development a...

journal_title：Contrast media & molecular imaging

authors： Meyer-Bäse A,Morra L,Meyer-Bäse U,Pinker K

更新日期：2020-08-28 00:00:00

abstract：:An experimental setup consisting of a hollow fiber module (HFM) was developed for the in vitro study of contrast agent (CA) permeability. Controllable flow and known fiber characteristics allowed permeability studies under well-defined conditions with CAs of different molecular weight (MW). In the MRI experiments perf...

journal_title：Contrast media & molecular imaging

authors： Heilmann M,Vautier J,Robert P,Volk A

更新日期：2009-03-01 00:00:00

abstract：:The combination of the size-dependent properties of nanomaterials with radioisotopes is emerging as a novel tool for molecular imaging. There are numerous examples already showing how the controlled synthesis of nanoparticles and the incorporation of a radioisotope in the nanostructure offer new features beyond the si...

journal_title：Contrast media & molecular imaging

authors： Pellico J,Llop J,Fernández-Barahona I,Bhavesh R,Ruiz-Cabello J,Herranz F

更新日期：2017-11-21 00:00:00

abstract：Aim:To evaluate reproducibility and stability of radiomic features as effects of the use of different volume segmentation methods and reconstruction settings. The potential of radiomics in really capturing the presence of heterogeneous tumor uptake and irregular shape was also investigated. Materials and Methods:An an...

journal_title：Contrast media & molecular imaging

authors： Gallivanone F,Interlenghi M,D'Ambrosio D,Trifirò G,Castiglioni I

更新日期：2018-09-10 00:00:00

abstract：:Chemical exchange saturation transfer (CEST) imaging is an emerging MRI technique relying on the use of endogenous or exogenous molecules containing exchangeable proton pools. The heterogeneity of the water resonance frequency offset plays a key role in the occurrence of artifacts in CEST-MR images. To limit this draw...

journal_title：Contrast media & molecular imaging

authors： Stancanello J,Terreno E,Castelli DD,Cabella C,Uggeri F,Aime S

更新日期：2008-07-01 00:00:00

abstract：:Monodisperse mesoporous silica (mSiO(2) ) coated superparamagnetic iron oxide (Fe(3) O(4) @mSiO(2) ) nanoparticles (NPs) have been developed as a potential magnetic resonance imaging (MRI) T(2) contrast agent. To evaluate the effect of surface coating on MRI contrast efficiency, we examined the proton relaxivities of ...

journal_title：Contrast media & molecular imaging

authors： Ye F,Laurent S,Fornara A,Astolfi L,Qin J,Roch A,Martini A,Toprak MS,Muller RN,Muhammed M

更新日期：2012-09-01 00:00:00

abstract：:In this study we report the development of a bioconjugate between superparamagnetic iron oxide nanoparticles and Phl p5a (one of the major allergens from grass pollen). The bioconjugate also contains an optical probe (Alexa647) conjugated to the nanoparticle via biotin-streptavidin association. We show that this conju...

journal_title：Contrast media & molecular imaging

authors： Herranz F,Schmidt-Weber CB,Shamji MH,Narkus A,Ruiz-Cabello J,Vilar R

更新日期：2012-07-01 00:00:00

abstract：:A novel tumor stroma targeting and membrane-penetrating cyclic peptide, named iCREKA, was designed and labeled by fluorescein isothiocyanate (FITC) and positron emitter 18F to build the tumor-targeting tracers. The FITC-iCREKA was proved to have significantly higher cellular uptake in the glioma U87 cells in the prese...

journal_title：Contrast media & molecular imaging

authors： Wang LJ,Li HS,Wang QS,Wu HB,Han YJ,Zhou WL,Wang M,Huang S

更新日期：2018-03-04 00:00:00

abstract：:Gold nanoparticles coated by gadolinium (III) chelates (Au@DTDTPA) where DTDTPA is a dithiolated bisamide derivative of diethylenetriamine-N,N,N',N'',N''-pentaacetic acid (DTPA), constituted contrast agents for both X-ray computed tomography and magnetic resonance imaging. In an MRI context, highly stable Gd(3+) compl...

journal_title：Contrast media & molecular imaging

authors： Mogilireddy V,Déchamps-Olivier I,Alric C,Laurent G,Laurent S,Vander Elst L,Muller R,Bazzi R,Roux S,Tillement O,Chuburu F

更新日期：2015-05-01 00:00:00

abstract：Rationale:To assess the diagnostic value of 18F-FDG-PET/CT for different retroperitoneal soft tissue sarcomas (STS) and other similar tumors. To analyze the predictive value of 18F-FDG-PET/CT for histological grade and main prognostic factors. Methods:195 patients with 44 different diseases have been included. Relatio...

journal_title：Contrast media & molecular imaging

authors： Liu DN,Li ZW,Wang HY,Zhao M,Zhao W,Hao CY

更新日期：2018-07-02 00:00:00

abstract：:A specific mouse whole body coil and a dedicated gradient system at 4.7 T were coupled with an ultra-fast 3D gradient echo MRI and keyhole reconstruction technique to obtain 3D whole-body dynamic T(1)-weighted or T(2)*-weighted imaging. The technique was used to visualize the real-time distribution of non-targeting T(...

journal_title：Contrast media & molecular imaging

authors： Bled E,Hassen WB,Pourtau L,Mellet P,Lanz T,Schüler D,Voisin P,Franconi JM,Thiaudière E,Miraux S

更新日期：2011-07-01 00:00:00

abstract：:The use of superparamagnetic iron oxide (SPIO) for labeling cells holds great promise for clinically applicable cell tracking using magnetic resonance imaging. For clinical application, an effectively and specifically labeled cell preparation is highly desired (i.e. a large amount of intracellular iron and a negligibl...

journal_title：Contrast media & molecular imaging

authors： van Buul GM,Farrell E,Kops N,van Tiel ST,Bos PK,Weinans H,Krestin GP,van Osch GJ,Bernsen MR

更新日期：2009-09-01 00:00:00

abstract：:MRI cell tracking is a promising technique to track various cell types (stem cells, tumor cells, etc.) in living animals. Usually, cells are incubated with iron oxides (T(2) contrast agent) in order to take up the particles before being injected in vivo. Iron oxide quantification is important in such studies for valid...

journal_title：Contrast media & molecular imaging

authors： Danhier P,De Preter G,Boutry S,Mahieu I,Leveque P,Magat J,Haufroid V,Sonveaux P,Bouzin C,Feron O,Muller RN,Jordan BF,Gallez B

更新日期：2012-05-01 00:00:00

abstract：:Quantum dot micelles (pQDs) with a paramagnetic coating are promising nanoparticles for bimodal molecular imaging. Their bright fluorescence allows for optical detection, while their Gd payload enables visualization with contrast-enhanced MRI. A popular approach in molecular MRI is the targeting of abundantly expresse...

journal_title：Contrast media & molecular imaging

authors： Starmans LW,Kok MB,Sanders HM,Zhao Y,Donegá Cde M,Meijerink A,Mulder WJ,Grüll H,Strijkers GJ,Nicolay K

更新日期：2011-03-01 00:00:00

abstract：Objective:The purpose of this study was to demonstrate the feasibility of using hyperpolarized carbon-13 (13C) metabolic imaging with [1-13C]-labeled pyruvate for evaluating real-time in vivo metabolism of orthotopic diffuse intrinsic pontine glioma (DIPG) xenografts. Materials and Methods:3D 13C magnetic resonance sp...

journal_title：Contrast media & molecular imaging

authors： Autry AW,Hashizume R,James CD,Larson PEZ,Vigneron DB,Park I

更新日期：2018-07-30 00:00:00

abstract：:The over-expression of sialic acid on the surface of cancer cells compared with normal ones makes this nine-carbon sugar an attractive biomarker for molecular diagnosis and therapy. Here, we describe a study on the molecular recognition of sialic acid end groups on the surface of human glioma cells by (160)Tb-DTPA-EN(...

journal_title：Contrast media & molecular imaging

authors： Djanashvili K,Koning GA,van der Meer AJ,Wolterbeek HT,Peters JA

更新日期：2007-01-01 00:00:00