E-selectin targeting to visualize tumors in vivo.

abstract：:Advances in regenerative medicine are rapidly transforming healthcare. A cornerstone of regenerative medicine is the introduction of cells that were grown or manipulated in vitro. Key questions that arise after these cells are re-introduced are: whether these cells are localized in the appropriate site; whether cells ...

journal_title：Contrast media & molecular imaging

authors： Modo M,Kolosnjaj-Tabi J,Nicholls F,Ling W,Wilhelm C,Debarge O,Gazeau F,Clement O

更新日期：2013-11-01 00:00:00

abstract：:Quantum dots (QDs) are fluorescent nanoparticles with broad excitation and narrow, wavelength-tunable emission spectra. They are used extensively for in vitro fluorescence imaging studies and more recently for in vivo small animal and pre-clinical studies. To date there has been little concern about the selection of Q...

journal_title：Contrast media & molecular imaging

authors： Rosenblum LT,Kosaka N,Mitsunaga M,Choyke PL,Kobayashi H

更新日期：2011-05-01 00:00:00

abstract：:Knowledge of the longitudinal and transverse relaxation times (T(1) and T(2)) of water protons in an aqueous solution of an MRI contrast agent is essential for its characterization. These parameters can be measured at low field on low resolution spectrometers or at high field on high resolution spectrometers. The reli...

journal_title：Contrast media & molecular imaging

authors： Henoumont C,Laurent S,Vander Elst L

更新日期：2009-11-01 00:00:00

abstract：:The gonadotropin-releasing hormone (GnRH) receptor is overexpressed in the majority of tumors of the human reproductive system. The purpose of this study was to develop an 18F-labeled peptide for tumor GnRH receptor imaging. In this study, the GnRH (pGlu1-His2-Trp3-Ser4-Tyr5-Gly6-Leu7-Arg8-Pro9-Gly10-NH2) peptide anal...

journal_title：Contrast media & molecular imaging

authors： Huang S,Li H,Han Y,Fu L,Ren Y,Zhang Y,Li Y,Sun P,Wang M,Wu H,Wang Q,Hu K

更新日期：2019-03-07 00:00:00

abstract：:Ferrite nanoparticles (F-NPs) can transform both cancer diagnostics and therapeutics. Superparamagnetic F-NPs exhibit high magnetic moment and susceptibility such that in presence of a static magnetic field transverse relaxation rate of water protons for MRI contrast is augmented to locate F-NPs (i.e., diagnostics) an...

journal_title：Contrast media & molecular imaging

authors： Hyder F,Manjura Hoque S

更新日期：2017-12-11 00:00:00

abstract：:Recent advances in artificial intelligence (AI) and deep learning (DL) have impacted many scientific fields including biomedical maging. Magnetic resonance imaging (MRI) is a well-established method in breast imaging with several indications including screening, staging, and therapy monitoring. The rapid development a...

journal_title：Contrast media & molecular imaging

authors： Meyer-Bäse A,Morra L,Meyer-Bäse U,Pinker K

更新日期：2020-08-28 00:00:00

abstract：:Various studies have shown that various cell types can be labeled with iron oxide particles and visualized by magnetic resonance imaging (MRI). However, reported protocols for cell labeling show a large variation in terms of labeling dose and incubation time. It is therefore not clear how different labeling protocols ...

journal_title：Contrast media & molecular imaging

authors： van Tiel ST,Wielopolski PA,Houston GC,Krestin GP,Bernsen MR

更新日期：2010-09-01 00:00:00

abstract：:The transplantation of pancreatic islets containing β-cells, which produce insulin, is an alternative approach to the treatment of type 1 diabetes mellitus. The non-invasive visualization of transplanted islets can be performed using MRI; however, this requires labeling of the islets with a suitable contrast agent pri...

journal_title：Contrast media & molecular imaging

authors： Herynek V,Berková Z,Dovolilová E,Jirák D,Kříž J,Girman P,Saudek F,Hájek M

更新日期：2011-07-01 00:00:00

abstract：:The use of superparamagnetic iron oxide (SPIO) for labeling cells holds great promise for clinically applicable cell tracking using magnetic resonance imaging. For clinical application, an effectively and specifically labeled cell preparation is highly desired (i.e. a large amount of intracellular iron and a negligibl...

journal_title：Contrast media & molecular imaging

authors： van Buul GM,Farrell E,Kops N,van Tiel ST,Bos PK,Weinans H,Krestin GP,van Osch GJ,Bernsen MR

更新日期：2009-09-01 00:00:00

abstract：:Self-aggregation of dyes even at low concentrations poses a considerable challenge in preparing sufficiently bright molecular probes for in vivo imaging, particularly in the conjugation of near infrared cyanine dyes to polypeptides with multiple labeling sites. Such self-aggregation leads to a significant energy trans...

journal_title：Contrast media & molecular imaging

authors： Zhegalova NG,He S,Zhou H,Kim DM,Berezin MY

更新日期：2014-09-01 00:00:00

abstract：:An experimental setup consisting of a hollow fiber module (HFM) was developed for the in vitro study of contrast agent (CA) permeability. Controllable flow and known fiber characteristics allowed permeability studies under well-defined conditions with CAs of different molecular weight (MW). In the MRI experiments perf...

journal_title：Contrast media & molecular imaging

authors： Heilmann M,Vautier J,Robert P,Volk A

更新日期：2009-03-01 00:00:00

abstract：:The combination of the size-dependent properties of nanomaterials with radioisotopes is emerging as a novel tool for molecular imaging. There are numerous examples already showing how the controlled synthesis of nanoparticles and the incorporation of a radioisotope in the nanostructure offer new features beyond the si...

journal_title：Contrast media & molecular imaging

authors： Pellico J,Llop J,Fernández-Barahona I,Bhavesh R,Ruiz-Cabello J,Herranz F

更新日期：2017-11-21 00:00:00

abstract：:The development of molecular probes and novel imaging modalities, allowing better resolution and specificity, is associated with an increased potential for molecular imaging of atherosclerotic plaques especially in basic and pre-clinical research applications. In that context, a photoacoustic molecular probe based on ...

journal_title：Contrast media & molecular imaging

authors： Rouleau L,Berti R,Ng VW,Matteau-Pelletier C,Lam T,Saboural P,Kakkar AK,Lesage F,Rhéaume E,Tardif JC

更新日期：2013-01-01 00:00:00

abstract：:Glioblastoma (GBM) is the most common primary malignant type of brain neoplasm in adults and carries a dismal prognosis. The current standard of care for GBM is surgical excision followed by radiation therapy (RT) with concurrent and adjuvant temozolomide-based chemotherapy (TMZ) by six additional cycles. In addition,...

journal_title：Contrast media & molecular imaging

authors： Zikou A,Sioka C,Alexiou GA,Fotopoulos A,Voulgaris S,Argyropoulou MI

更新日期：2018-12-02 00:00:00

abstract：:Recent reports have claimed a superior performance of HEPES buffer in comparison to alternative buffer systems for (67/68) Ga labeling in aqueous media. In this paper we report spectroscopic ((1) H and (71) Ga NMR), radiochemical, mass spectrometry and theoretical modeling studies on the Ga(3+)/HEPES system (HEPES = N...

journal_title：Contrast media & molecular imaging

authors： Martins AF,Prata MI,Rodrigues SP,Geraldes CF,Riss PJ,Amor-Coarasa A,Burchardt C,Kroll C,Roesch F

更新日期：2013-05-01 00:00:00

abstract：:The purpose of this study was to determine if parameters derived from diffusion-weighted (DW-) and dynamic contrast-enhanced (DCE-) magnetic resonance imaging (MRI) can help to assess early response to peptide receptor radionuclide therapy (PRRT) with 90Y-DOTATOC in neuroendocrine hepatic metastases (NET-HM). Twenty p...

journal_title：Contrast media & molecular imaging

authors： Weikert T,Maas OC,Haas T,Klarhöfer M,Bremerich J,Forrer F,Sauter AW,Sommer G

更新日期：2019-11-11 00:00:00

abstract：:The purpose was to investigate whether MnCl(2) can serve as an MRI contrast agent to detect chronic cryoinjury infarction in pigs in vivo and whether MnCl(2) causes significant hemodynamic disturbances. Hearts were subjected to a topical 2 min cryothermia to establish myocardial infarction (MI). Thereafter GdDTPA-enha...

journal_title：Contrast media & molecular imaging

authors： Yang Y,de Gervai PD,Sun J,Gruwel ML,Kupriyanov V

更新日期：2011-11-01 00:00:00

abstract：:Quantum dot micelles (pQDs) with a paramagnetic coating are promising nanoparticles for bimodal molecular imaging. Their bright fluorescence allows for optical detection, while their Gd payload enables visualization with contrast-enhanced MRI. A popular approach in molecular MRI is the targeting of abundantly expresse...

journal_title：Contrast media & molecular imaging

authors： Starmans LW,Kok MB,Sanders HM,Zhao Y,Donegá Cde M,Meijerink A,Mulder WJ,Grüll H,Strijkers GJ,Nicolay K

更新日期：2011-03-01 00:00:00

abstract：:For in vivo applications of magnetically labeled stem cells, biological effects of the labeling procedure have to be precluded. This study evaluates the effect of different ferucarbotran cell labeling protocols on chondrogenic differentiation of human mesenchymal stem cells (hMSC) as well as their implications for MR ...

journal_title：Contrast media & molecular imaging

authors： Henning TD,Sutton EJ,Kim A,Golovko D,Horvai A,Ackerman L,Sennino B,McDonald D,Lotz J,Daldrup-Link HE

更新日期：2009-07-01 00:00:00

abstract：:Perfluorocarbon (PFC) double emulsions loaded with a water-soluble, therapeutic agent can be triggered by ultrasound in a process known as acoustic droplet vaporization. Elucidating the stability and biodistribution of these sonosensitive vehicles and encapsulated agents is critical in developing targeted drug deliver...

journal_title：Contrast media & molecular imaging

authors： Fabiilli ML,Piert MR,Koeppe RA,Sherman PS,Quesada CA,Kripfgans OD

更新日期：2013-07-01 00:00:00

abstract：:We evaluated the difference in the status of dopamine transporters (DATs) depending on Parkinsonism, cerebellar, and autonomic features using F-18 FP-CIT positron emission tomography (PET) in multiple system atrophy with cerebellar ataxia (MSA-C). We also assessed whether the DAT PET could be useful in the management ...

journal_title：Contrast media & molecular imaging

authors： Jeong YJ,Cheon SM,Kang DY,Kim JW

更新日期：2017-11-29 00:00:00

abstract：:Purpose. To investigate the value of SUV metrics and radiomic features based on the ability of 18F-FDG PET/CT in differentiating between breast lymphoma and breast carcinoma. Methods. A total of 67 breast nodules from 44 patients who underwent 18F-FDG PET/CT pretreatment were retrospectively analyzed. Radiomic paramet...

journal_title：Contrast media & molecular imaging

authors： Ou X,Wang J,Zhou R,Zhu S,Pang F,Zhou Y,Tian R,Ma X

更新日期：2019-02-25 00:00:00

abstract：:The aim of the present study was to test alginate gels of different compositions as a system for controlled release of manganese ions (Mn(2+)) for application in manganese-enhanced MRI (MEMRI), in order to circumvent the challenge of achieving optimal MRI resolution without resorting to high, potentially cytotoxic dos...

journal_title：Contrast media & molecular imaging

authors： Mørch YA,Sandvig I,Olsen O,Donati I,Thuen M,Skjåk-Braek G,Haraldseth O,Brekken C

更新日期：2012-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this pilot study was to establish the ability of dynamic contrast enhanced computed tomography (DCE-CT) to detect changes in tumor blood flow (BF) and oxygenation induced by vasoactive substances in rats. MATERIALS AND METHODS:Under ultrasound guidance, a fiber-optic probe was g...

journal_title：Contrast media & molecular imaging

authors： Pollard RE,Larson RF

更新日期：2011-01-01 00:00:00

abstract：:D-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) is a Food and Drug Administration (FDA) approved biomaterial that can form nanosized micelles in aqueous solution. TPGS micelles stand as an interesting system to perform drug delivery as they can carry lipophilic drugs and overcome P glycoprotein efflux as well...

journal_title：Contrast media & molecular imaging

authors： Tesan FC,Nicoud MB,Nuñez M,Medina VA,Chiappetta DA,Salgueiro MJ

更新日期：2019-04-23 00:00:00

abstract：:Physicians and scientists use a broad spectrum of terms to classify contrast media (CM)-induced adverse reactions. In particular, the designation of hypersensitivity reactions is quite varied. Consequently, comparisons of different papers dealing with this subject are difficult or even impossible. Moreover, general de...

journal_title：Contrast media & molecular imaging

authors： Böhm I,Heverhagen JT,Klose KJ

更新日期：2012-11-01 00:00:00

abstract：Background:To evaluate the clinical and prognostic value of PET/CT with combination of 68Ga-DOTATATE and 18F-FDG in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). Method:83 patients of GEP-NENs who underwent 68Ga-DOTATATE and 18F-FDG PET/CT were enrolled between June 2013 and December 2016. Well-different...

journal_title：Contrast media & molecular imaging

authors： Zhang P,Yu J,Li J,Shen L,Li N,Zhu H,Zhai S,Zhang Y,Yang Z,Lu M

更新日期：2018-02-26 00:00:00

abstract：:A new high-throughput MRI method for screening chemical exchange saturation transfer (CEST) agents is demonstrated, allowing simultaneous testing of multiple samples with minimal attention to sample configuration and shimming of the main magnetic field (B(0)). This approach, which is applicable to diamagnetic, paramag...

journal_title：Contrast media & molecular imaging

authors： Liu G,Gilad AA,Bulte JW,van Zijl PC,McMahon MT

更新日期：2010-05-01 00:00:00

abstract：Objective:The purpose of this study was to demonstrate the feasibility of using hyperpolarized carbon-13 (13C) metabolic imaging with [1-13C]-labeled pyruvate for evaluating real-time in vivo metabolism of orthotopic diffuse intrinsic pontine glioma (DIPG) xenografts. Materials and Methods:3D 13C magnetic resonance sp...

journal_title：Contrast media & molecular imaging

authors： Autry AW,Hashizume R,James CD,Larson PEZ,Vigneron DB,Park I

更新日期：2018-07-30 00:00:00

abstract：:An observational study was set up to assess the feasibility of [18F]FPRGD2 PET/CT for imaging patients with multiple myeloma (MM) and to compare its detection rate with low dose CT alone and combined [18F]NaF/[18F]FDG PET/CT images. Four patients (2 newly diagnosed patients and 2 with relapsed MM) were included and un...

journal_title：Contrast media & molecular imaging

authors： Withofs N,Cousin F,De Prijck B,Bonnet C,Hustinx R,Gambhir SS,Beguin Y,Caers J

更新日期：2017-07-27 00:00:00