Abstract:
OBJECTIVES:This study aimed to investigate the levels of 11 oral species in plaque samples and cytokine levels in biofluid samples of patients with idiopathic uveitis (IU) and systemically healthy individuals (H) with or without gingival inflammation. MATERIAL & METHODS:Twenty-one patients with IU (n = 21), and 22 systemically healthy individuals (n = 22) were enrolled in the study. Clinical periodontal measurements were recorded. Cytokine levels in the biofluid samples were determined by ELISA. Bacterial gene copy numbers were determined by qPCR on plaque microbial DNA preparations. RESULTS:According to two-step cluster analysis, anova and t-test: GCF, serum and salivary TNF-α, IL-17A, IL-17A/E; GCF and serum IL-6; salivary IL-17F, and salivary and serum IL-17A/F levels were higher in the IU group than the H group (p < 0.05). However, serum IL-10 and IL-17E levels were higher in the H group than the IU group (p < 0.05). A. actinomycetemcomitans, F. nucleatum, S. oralis, A. naeslundii, and V. dispar counts were higher in IU group compared to H group (p < 0.05). CONCLUSION:Altered local and systemic cytokine profiles are associated with differences in the microbial plaque composition in IU. Anti-inflammatory cytokines; IL-10, IL-17E are reduced in patients with IU and Th-1 and Th-17 driven inflammatory responses in biofluids are altered.
journal_name
J Clin Periodontoljournal_title
Journal of clinical periodontologyauthors
Akcalı A,Güven Yılmaz S,Lappin DF,Eğrilmez S,Buduneli Ndoi
10.1111/jcpe.12555subject
Has Abstractpub_date
2016-08-01 00:00:00pages
637-45issue
8eissn
0303-6979issn
1600-051Xjournal_volume
43pub_type
杂志文章abstract:AIM:This study aims to explore the effect of two commercially available haemostatic agents (i.e., collagen sponge and oxide cellulose) on early healing of the extraction socket. MATERIAL AND METHODS:In a murine model, bilateral maxillary first molars were extracted and the sockets were filled with or without haemostat...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.13122
更新日期:2019-07-01 00:00:00
abstract:AIM:Our aim was to measure the association of maternal periodontitis with low birth weight (LBW), pre-term LBW, and intra-uterine growth restriction. MATERIAL AND METHODS:An inclusive case-control design including subjects examined for periodontitis through attachment loss, information on perinatal outcomes and genera...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2006.01012.x
更新日期:2007-01-01 00:00:00
abstract::Root resorption of 2nd molars in proximity to non-erupted 3rd molars has been widely reported. The purpose of this study was to determine the prevalence of root resorption in second molars adjacent to non-erupted third molars. Its association to age and gender of the patient, location and inclination of the non-erupte...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1996.tb00616.x
更新日期:1996-09-01 00:00:00
abstract::A cross-sectional study was designed to evaluate the periodontal status of 85 12-18 year-old French adolescents with insulin-dependent diabetes (IDDM) and 38 healthy controls in the same age group. The clinical examination consisted of plaque control and gingival inflammation evaluation and probing attachment level. T...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1992.tb01710.x
更新日期:1992-10-01 00:00:00
abstract::The effect of a collagen gel matrix as a submembranous space-maintaining material was evaluated in guided tissue regeneration procedures. In 4 dogs, contralateral surgical circular fenestration defects, 5 mm in diameter, were produced at the midbuccal aspect of the alveolar bone in 8 maxillary canines. Removal of bone...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1996.tb00496.x
更新日期:1996-01-01 00:00:00
abstract::Healing events following nonsurgical periodontal therapy were studied, comparing the effect of a single initial instrumentation to the effect of 3 instrumentations, each separated by 3 months. Incisors, cuspids and premolars with periodontal pockets up to 11 mm deep in 13 patients were treated by plaque control and su...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1984.tb00839.x
更新日期:1984-02-01 00:00:00
abstract::Alveolar bone loss measurements made using digitized dental radiographs have been shown to be precise and accurate. We determined the influence of alignment errors introduced when exposing the radiographs on the precision and accuracy of bone loss measurements. Bitewing radiographs of 15 day skulls were obtained using...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1991.tb00114.x
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND AND AIM:Tobacco users and especially cigarette smokers are at higher risk than non-smokers for periodontal disease. The pathogenic mechanism has been proposed to be the vasoconstrictive properties of nicotine, with reduced gingival blood flow (GBF) as a contributing factor in the development of periodontal d...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2002.290911.x
更新日期:2002-09-01 00:00:00
abstract::The osteoclast may play an important rŏle in the variable rate of osseous destruction seen in periodontitis. Current understanding of various aspects of the osteoclast may help explain this fact. This review paper will first look at two theories of cell origin of the osteoclast: the multipotential osteoprogenitor cell...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051x.1986.tb02220.x
更新日期:1986-04-01 00:00:00
abstract:AIM:To study whether periodontal condition is associated with the development of type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS:A population-based follow-up study was conducted among persons born in 1935 and living in the city of Oulu, Finland (n = 395). The baseline examinations were done during 1990-1992, an...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.13005
更新日期:2018-11-01 00:00:00
abstract::Both transforming growth factor-beta (TGF-beta) and platelet-derived growth factor (PDGF) have been shown to affect cell proliferation in vitro. The hypothesis being tested was that the effects of the 2 cytokines would be modulated by the presence of serum in the medium. Gingival fibroblasts, obtained from periodontal...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1998.tb02363.x
更新日期:1998-01-01 00:00:00
abstract::The purpose of this study was to compare 2 groups of adolescents undergoing orthodontic treatment with fixed appliances to determine whether once daily use of a mouthrinse containing 1.5% H2O2 along with toothbrushing would be better than toothbrushing alone in maintaining their periodontal health. The 2 groups of sub...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1989.tb02137.x
更新日期:1989-10-01 00:00:00
abstract:AIM:The aim of the study was to evaluate the prevalence and simultaneous occurrence of periodontal disease and dental caries in Finnish adults. MATERIAL AND METHODS:The study was performed as part of the nationally representative Health 2000 Survey. The study population was 5255 subjects aged 30 years and older. Probi...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2010.01620.x
更新日期:2010-11-01 00:00:00
abstract:AIMS:To systematically review the literature addressing the following focused questions: "What is the efficacy of either (#1) alternative or (#2) additional methods to professional mechanical plaque removal (PMPR) on progression of attachment loss during supportive periodontal therapy (SPT) in periodontitis patients?"....
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.13269
更新日期:2020-07-01 00:00:00
abstract:FOCUSED QUESTION:What is the clinical influence of probiotics as an adjunctive therapy of scaling and root planing (SRP) when compared with SRP alone or in combination with placebo in the treatment of chronic periodontitis (CP). METHODS:Electronic databases were searched up to July 2015. Randomized controlled trials (...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/jcpe.12545
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND AND AIMS:Induction of the pro-fibrotic growth factor TGF-beta1 has been suggested as a possible mechanism through which immunosuppressant drugs may induce gingival overgrowth. This study aims to investigate plasma levels of TGF-beta1 and relate them to the development and severity of gingival overgrowth in i...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2004.00572.x
更新日期:2004-10-01 00:00:00
abstract::A total of 383 students, ages 12-16, were examined clinically to determine periodontal attachment loss by a trained examiner, utilizing standard techniques. 70 of these were selected, for whom bitewing radiographs were available for assessment of early alveolar bone loss by 2 radiologists and a general dentist, utiliz...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1985.tb00922.x
更新日期:1985-03-01 00:00:00
abstract::A double-blind, randomised, 6-month clinical trial with parallel group design in 149 patients with gingivitis was conducted to study the efficacy and safety of delmopinol hydrochloride 2 mg/ml (0.2% w/v, Decapinol Mouthwash) used for partly supervised mouthrinsing in comparison with chlorhexidine digluconate 2 mg/ml (...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-051x.1998.tb02516.x
更新日期:1998-09-01 00:00:00
abstract:INTRODUCTION:The remit of this group was to update the knowledge base on periodontal diseases and health. MATERIAL AND METHODS:The literature was systematically searched and critically reviewed in five specific topics. RESULTS:Prevalence of periodontitis: The data suggest a trend towards a lower prevalence of periodo...
journal_title:Journal of clinical periodontology
pub_type: 共识发展会议,杂志文章
doi:10.1111/j.1600-051X.2008.01278.x
更新日期:2008-09-01 00:00:00
abstract::Periodontal microbiology is reviewed with regard to the potential of certain characteristics to serve as markers of high risk groups or individuals for periodontal diseases. The generally accepted associations between particular organisms and the various periodontal diseases are discussed. The usefulness of various cl...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051x.1990.tb01040.x
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to conduct a review on quality of reporting on descriptive studies in implant dentistry using the STROBE Statement and to analyse possible changes in quality of reporting on descriptive studies in implant dentistry over time. MATERIAL AND METHODS:A hand search to select descriptive...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051X.2011.01834.x
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:While there seems to be a common belief that psychosocial stress affects oral hygiene behavior, this assumption has rarely been proved. The present study thus aims to analyse stress effects on oral hygiene. MATERIAL AND METHODS:16 matched pairs of medical students each consisting of 1 student participating ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2001.028005459.x
更新日期:2001-05-01 00:00:00
abstract::This paper summarizes the rationale for the application of microbiology in the management of destructive periodontal diseases. The subgingival microbiota in patients with severe periodontitis is complex and contains high numbers of obligate anaerobic bacteria as well as facultative micro-organisms. It has become clear...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051x.1991.tb02308.x
更新日期:1991-07-01 00:00:00
abstract:BACKGROUND AND AIMS:Periodontitis is an infection with an episodic nature of tissue support destruction. The aim of this work was to determine the levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal pathogens and inflammatory cells in periodontal sites characterized by active periodontal connectiv...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2007.01190.x
更新日期:2008-03-01 00:00:00
abstract::Premature exposure of membrane in the oral cavity is considered the most common complication as well as a reason for failure or incomplete success of guided tissue regeneration, as the exposed membrane undergoes plaque accumulation. A method to control, or at least to reduce the bacterial invasion of the membrane allo...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1995.tb00155.x
更新日期:1995-04-01 00:00:00
abstract:AIM:The primary goal was to compare the amount of keratinized tissue width (KTW) gain after free gingival graft (FGG) procedures around implants and teeth after 6 and 12 months of healing. MATERIALS AND METHODS:Patients with mucogingival defects (<2 mm of KT) around teeth and implants underwent a gingival augmentation...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.13394
更新日期:2021-02-01 00:00:00
abstract::Little is known about the relationship of aging to periodontal disease. The immune response undergoes aging-related changes resulting in loss of functional capacity. The aim of this study was to investigate the relationship between levels of serum IgG antibodies against suspected periodontal pathogenic microorganisms ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1995.tb01782.x
更新日期:1995-11-01 00:00:00
abstract:AIM:To evaluate the impact of two non-surgical periodontal treatment modalities on metabolic and periodontal clinical parameters in subjects with type 2 diabetes mellitus (T2DM) and poor glycaemic control and chronic periodontitis. MATERIAL AND METHODS:A randomized controlled clinical trial was conducted. Ninety-three...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1111/jcpe.12991
更新日期:2018-09-01 00:00:00
abstract:AIM:To evaluate the effectiveness of mobile applications and text messages, compared with conventional oral hygiene instructions, for improving oral health knowledge and/or reducing gingival inflammation, when delivered to adolescents, adults and mothers of young children. METHODS:Randomized clinical trials evaluating...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/jcpe.13083
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND, AIMS:Zinc-citrate-containing toothpastes have previously been suggested to be of value at inhibiting plaque and gingival inflammation. Present formulations have included triclosan which is thought to contribute major antibacterial/antiplaque effects. Alternative antimicrobial agents and other ingredients su...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-051x.2001.028002157.x
更新日期:2001-02-01 00:00:00