Abstract:
:The osteoclast may play an important rŏle in the variable rate of osseous destruction seen in periodontitis. Current understanding of various aspects of the osteoclast may help explain this fact. This review paper will first look at two theories of cell origin of the osteoclast: the multipotential osteoprogenitor cell theory and the hemopoietic stem cell theory. Next, ultrastructural features characteristic to the cell such as the ruffled border, clear zone, and lysosomal system, will be discussed. Thirdly, current and proposed theories on the actual mechanism of bone degradation are considered. This includes the one-cell theory and the two-cell theory. Finally, elements which activate the osteoclast are enumerated and their delicate interplay is outlined. In the context of this information, pathways found in the periodontal lesion (microbial agents, inflammatory cells and their products) which attract and activate elements of the osteoclastic system are discussed.
journal_name
J Clin Periodontoljournal_title
Journal of clinical periodontologyauthors
Sterrett JDdoi
10.1111/j.1600-051x.1986.tb02220.xsubject
Has Abstractpub_date
1986-04-01 00:00:00pages
258-69issue
4eissn
0303-6979issn
1600-051Xjournal_volume
13pub_type
杂志文章,评审abstract:OBJECTIVES:The aim of this prospective, randomized, controlled clinical study was to compare the effectiveness of a newly developed ultrasonic device to that of scaling and root planing for non-surgical periodontal treatment. MATERIAL AND METHODS:Thirty-eight patients with moderate to advanced chronic periodontal dise...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-051X.2004.00496.x
更新日期:2004-06-01 00:00:00
abstract::In the present study, the effect of supra and subgingival plaque debridement on the dynamics of the subgingival microflora in deep pockets was investigated. 8 adult periodontitis patients participated in the study. In each patient, 4 clinically diseased sites were investigated microbiologically by phase contrast micro...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1988.tb01004.x
更新日期:1988-02-01 00:00:00
abstract::In four beagle dogs, periodontal tissue breakdown was experimentally induced around the upper left premolars (P1, P2 and P3). Wooden probes were inserted mesially and distally to each premolar. Six different probing forces were used in each dog. Microscopic examination showed: 1) the presence of an intact layer of epi...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1980.tb01975.x
更新日期:1980-08-01 00:00:00
abstract:AIM:There is a paucity of up-to-date data regarding prevalence and risk indicators of periodontitis in Italy. Therefore, the aim of this study was to evaluate the prevalence of periodontitis and its risk indicators among adults from an urban area in North Italy. MATERIAL AND METHODS:This cross-sectional survey used a ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12420
更新日期:2015-07-01 00:00:00
abstract:AIM:The objective of this study was to compare two different periodontal plastic surgery procedures to treat Miller's class I recession: a coronally advanced flap(control group) versus the pouch technique (test group), both of which were associated with connective tissue graft. METHODS:Forty consecutive patients were ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1111/jcpe.12207
更新日期:2014-04-01 00:00:00
abstract::Periodontitis (PD) is a chronic inflammatory disease characterised by tissue inflammation and destruction of the associated alveolar bone. It is caused by the colonisation of the bacterial plaque biofilm and the resultant host immune responses in the surrounding periodontal tissues. The pro-inflammatory cytokine IL-17...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/jcpe.12238
更新日期:2014-06-01 00:00:00
abstract::The concept of locally delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1998.tb02395.x
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:the aim of this study was to understand the cellular/molecular mechanisms of periodontal breakdown in a collagen-induced arthritis (CIA) model in mice to enhance the understanding of rheumatoid arthritis (RA)-associated alveolar bone loss in humans. MATERIALS AND METHODS:all analyses were performed on paired...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2010.01645.x
更新日期:2011-02-01 00:00:00
abstract::The purpose of this investigation was to analyze the clinical crown of the 3 tooth groups of the maxillary anterior sextant of the permanent dentition of normal subjects with respect to (i) width, length and the width/length ratios and (ii) determine if there is a correlation between tooth dimensions or tooth group ra...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.1999.260304.x
更新日期:1999-03-01 00:00:00
abstract::The present report describes the result of a clinical trial in which a group of adults have been maintained on a proper oral hygiene standard over a 6-year period. In 1971--72, 375 individuals were recruited to a test group and 180 to a control group. During the 6 years of trial, 65 persons from the test group and 34 ...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-051x.1981.tb02035.x
更新日期:1981-06-01 00:00:00
abstract::A socio-ecologic conceptual model for periodontal diseases has been proposed. The model, which includes 4 items: health-care organization, human biology, behavioral factors, and environment, has been tested on a random-sample of 50-year-old Oslo citizens. The investigation is based on a clinical examination as well as...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1993.tb00775.x
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:Quaternary ammonium compounds constitute a large group of antibacterial chemicals with a potential for inhibiting plaque and gingivitis. One compound, benzalkonium chloride (BC), may be of value, although there is a dearth of evidence to support efficacy. The aim of this study was to measure the ability of 2...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-051x.2000.027001037.x
更新日期:2000-01-01 00:00:00
abstract:INTRODUCTION:Chronic kidney disease (CKD) is associated with significant morbidity and mortality. There is a need to identify novel and modifiable risk factors in such patients. The periodontal component of the Renal Impairment In Secondary Care (RIISC) study aims to evaluate the association between chronic periodontit...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章
doi:10.1111/jcpe.12263
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:The antiplaque and antigingivitis effect of 3 dentifrices was evaluated using the 21-day partial-mouth experimental model of gingivitis. METHOD:25 volunteers took part in this cross-over, double-blind study, carried out in 4 phases of 21 days each. For each phase of the study, a toothshield of the IV quadra...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-051x.2000.027007494.x
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVE:To determine the concentration of cathepsin K secreted into the crevicular fluid around dental implants and its correlation with clinical parameters of healthy implants and implants showing clinical signs of peri-implantitis. MATERIAL AND METHODS:Nineteen patients with 40 implants with and without peri-impla...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2006.00904.x
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVES:The purpose of this article is to provide the necessary background and rationale for the accompanying studies, which are ultimately aimed at identifying genetic and environmental factors determining gingivitis susceptibility. MATERIALS AND METHODS:The literature on factors reported to modify the clinical ex...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051x.2004.00477.x
更新日期:2004-04-01 00:00:00
abstract:AIM:The objective of this literature review and subsequent case report is to discuss and illustrate the tunnel preparation procedure as a treatment alternative for furcation-involved molars. REVIEW OF THE LITERATURE:Furcation tunnel preparation, i.e., the creation of access for plaque control between periodontally dis...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:
更新日期:2001-01-01 00:00:00
abstract::The aims of the present study were to investigate whether the tachykinins substance P and neurokinin A were present in gingival crevicular fluid in both periodontal health and disease and to study the relationship with periodontal inflammation. Gingival crevicular fluid (GCF) was collected from a healthy, a gingivitis...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1997.tb01192.x
更新日期:1997-11-01 00:00:00
abstract:AIM AND BACKGROUND:The position of the most apical inter-dental portion of the alveolar crest is classically used in osseous resective surgery (ORS) to establish the amount of the inter-proximal and buccal/lingual bone resection. Supracrestal fibres connected to the root cementum are always present coronal to the alveo...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2006.01027.x
更新日期:2007-02-01 00:00:00
abstract:AIM:The purpose of this study was to investigate the relationship between cigarette smoking and the serum levels of folic acid, vitamin B(12) and some haematological variables in patients with periodontal disease. PATIENTS AND METHODS:The study base consisted of 88 volunteer patients with periodontal disease, includin...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2006.01003.x
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Gingival biotypes have been reported to influence the outcome of restorative therapies. The aim of this study was to evaluate the correlation of different morphometric parameters with the thickness of the buccal gingiva and alveolar bone at different apico-coronal levels. METHODS:In 60 periodontally healthy...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12169
更新日期:2013-12-01 00:00:00
abstract::The amount of plaque accumulation was assessed in an intraindividual study comprising 10 individuals. During different 2-week periods, the test subjects used nylon floss (unwaxed, waxed and specially treated), silk floss (unwaxed and waxed), Superfloss or triangular toothpicks for interdental tooth cleaning. Only teet...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1980.tb02158.x
更新日期:1980-12-01 00:00:00
abstract:FOCUSED QUESTION:What is the clinical influence of probiotics as an adjunctive therapy of scaling and root planing (SRP) when compared with SRP alone or in combination with placebo in the treatment of chronic periodontitis (CP). METHODS:Electronic databases were searched up to July 2015. Randomized controlled trials (...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/jcpe.12545
更新日期:2016-06-01 00:00:00
abstract:AIM:To investigate the impact of periodontal disease perception and oral health-related quality of life (OHRQoL), towards the initial periodontal treatment adherence (IPTA). MATERIAL AND METHODS:This prospective study included 571 patients (274 males and 297 females, mean age 63.1 ± 14.5) with periodontal disease, fro...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.13337
更新日期:2020-10-01 00:00:00
abstract::The aim of the study was to evaluate the adjunctive effect of systemic tetracycline (250 mg qds for 14 days) in sequential root planing and surgical phases of treatment in a randomised, double-blind controlled trial. 38 patients who were under 26 years of age, in good general health and with localised (15 test/15 cont...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-051x.1996.tb00592.x
更新日期:1996-07-01 00:00:00
abstract::A companion study reported that new connective tissue attachment did not occur to a surgically denuded root surface when transplanted into a normal periodontium. It was the purpose of this study to evaluate periodontal healing adjacent to a citric acid treated denuded root surface. In four squirrel monkeys, 12 teeth w...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1982.tb02105.x
更新日期:1982-11-01 00:00:00
abstract:BACKGROUND AND AIM:Tobacco users and especially cigarette smokers are at higher risk than non-smokers for periodontal disease. The pathogenic mechanism has been proposed to be the vasoconstrictive properties of nicotine, with reduced gingival blood flow (GBF) as a contributing factor in the development of periodontal d...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2002.290911.x
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:It is often recommended that manual toothbrushes should be replaced every 3 months. The aim of this study was to compare the effectiveness of new and 3-month-old toothbrushes in the removal of dental plaque. MATERIALS AND METHODS:A single examiner blind, randomized study was performed in which 40 adult pati...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-051x.2002.290709.x
更新日期:2002-07-01 00:00:00
abstract:AIM:The aim of this study was to determine whether an association exists between daily smoking and infrequent toothbrushing habits among adolescents. MATERIALS AND METHODS:Nationally representative samples of 14-, 16- and 18-year-old Finns (N=5643) took part in the survey. A 12-page structured questionnaire was posted...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2011.01709.x
更新日期:2011-05-01 00:00:00
abstract:AIM:The purpose of this study is to assess the associations between periodontal disease, tooth loss and liver diseases. MATERIALS AND METHODS:PubMed and Embase databases were utilized to search eligible studies. Odds ratio (OR) with 95% confidence interval (CI) was used as effect size to assess the associations betwee...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.13341
更新日期:2020-09-01 00:00:00