Abstract：
BACKGROUND:Quaternary ammonium compounds constitute a large group of antibacterial chemicals with a potential for inhibiting plaque and gingivitis. One compound, benzalkonium chloride (BC), may be of value, although there is a dearth of evidence to support efficacy. The aim of this study was to measure the ability of 2 BC mouthrinses (0.05% and 0.1%) to inhibit de novo plaque reformation. METHOD:A 4-day plaque regrowth model. For comparative purposes, a commercial mouthrinse containing cetyl pyridinium chloride (CPC) and a positive control chlorhexidine (CX) mouthrinse were also evaluated. RESULTS:Compared to water control, a reduction in plaque scores of 52% was noted for the CX mouthrinse, 22.5% for CPC and 5% and 6% for the 2 BC rinses. For plaque area, reductions of 84%, 47%, 16% and 15% were found for CX, CPC, and the 2 BC rinses, respectively. Significant reductions in plaque area compared to the water rinse were also seen with the 2 BC rinses (p<0.05). However, for both plaque score and plaque area, the CX and CPC rinses significantly reduced plaque compared to the BC rinses (p<0.0001). CONCLUSIONS:These findings would suggest that the 2 benzalkonium rinses would only have a limited value at inhibiting plaque formation.
journal_name
J Clin Periodontoljournal_title
Journal of clinical periodontologyauthors
Moran J,Addy M,Jackson R,Newcombe RGdoi
10.1034/j.1600-051x.2000.027001037.xkeywords:
subject
Has Abstractpub_date
2000-01-01 00:00:00pages
37-40issue
1eissn
0303-6979issn
1600-051Xjournal_volume
27pub_type
临床试验,杂志文章,随机对照试验abstract：:Chlorhexidine was tested for its ability to inhibit a wide range of glycosidic and proteolytic enzyme activities produced by Treponema denticola, Porphyromonas gingivalis, Bacteroides intermedius, Actinobacillus actinomycemcomitans, Capnocytophaga sputigena, Capnocytophaga gingivalis, Capnocytophaga orchracea, Capnocy...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1991.tb01693.x
更新日期：1991-02-01 00:00:00
abstract：:Periodontitis is an inflammatory disease of the periodontium which is characterized by a progressive destruction of the tissues supporting the tooth. Its primary etiology is an ill-defined series of microbial infections which may be composed of only some of the more than 300 species of bacteria currently recognized in...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,评审
doi：10.1111/j.1600-051x.1986.tb01485.x
更新日期：1986-05-01 00:00:00
abstract：:There have been no published reports characterizing gingival vascular function in humans of different ages. In this study, we compared gingival vascular dynamics in 60 healthy male humans ranging in age from 18-75 years (young, 18-25 years (Y); middle, 35-45 years (M); old, 65-75 years (O), 20 subjects/group). Both vi...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1993.tb00393.x
更新日期：1993-08-01 00:00:00
abstract：AIM:The aim of this study was to determine the prevalence and the structure of the leukotoxin promoter region of Actinobacillus actinomycetemcomitans in an ethnic Chinese population. METHOD:Subgingival plaque samples were collected from 42 patients with moderate to advanced periodontitis and 50 periodontally healthy p...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1034/j.1600-051x.2001.028009886.x
更新日期：2001-09-01 00:00:00
abstract：:This study was undertaken to test the hypothesis that seeded periodontal ligament cells are able to create new attachment. In one beagle dog, a premolar was removed and scrapings of the ligament were cultured. Artificial periodontal defects were made and the cultured ligament cells were seeded on the planed root surfa...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1991.tb01133.x
更新日期：1991-03-01 00:00:00
abstract：BACKGROUND:The aim of this randomized controlled clinical trial was to determine the effects of single-visit full-mouth ultrasonic debridement versus quadrant-wise therapy. MATERIAL AND METHODS:Thirty-six subjects with chronic periodontitis, were randomly allocated to three groups--quadrant-wise ultrasonic debridement...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2005.00775.x
更新日期：2005-07-01 00:00:00
abstract：PRIMARY OBJECTIVE:To evaluate a multicentre clinical trial design for testing powered toothbrushes. SECONDARY OBJECTIVE:To compare the efficacy of a prototype brush head (N2.3) for the Philips Jordan Sensiflex 2000 powered toothbrush (PTB) to that of Braun Oral-B D15 PTB in removing dental plaque MATERIAL AND METHODS...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1034/j.1600-051x.2002.291003.x
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVES:Assessment of patient-related factors contributing (1) to tooth loss and (2) to the quality of treatment outcome 10 years after initiation of anti-infective therapy. MATERIAL AND METHODS:All patients who had received active periodontal treatment 10 years ago by the same examiner were recruited consecutively...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2007.01184.x
更新日期：2008-02-01 00:00:00
abstract：AIM:the purpose of the present study was to assess the effect of non-surgical periodontal therapy on glycaemic control of type 2 diabetes patients with moderate-to-severe periodontitis. MATERIALS AND METHODS:this was a randomized, controlled clinical trial of patients with type 2 diabetes. A total of 60 patients with ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2010.01652.x
更新日期：2011-02-01 00:00:00
abstract：:The purpose of this study was to assess the effect of rinsing and topical application of sanguinarine on labial surface plaque accumulation, compared with topically applied water, and compared with rinsing with chlorhexidine, while refraining from all oral hygiene measures for 5 days. Color photographs of the disclose...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1988.tb01002.x
更新日期：1988-02-01 00:00:00
abstract：:116 subjects were recruited from a population of patients previously treated for adult periodontitis and maintained in periodontal health by means of periodic prophylaxes every 3-6 months. The subjects were divided into a control (C) and a test (T) group. A total of 33 patients in the T group and 47 in the C group com...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1989.tb01622.x
更新日期：1989-02-01 00:00:00
abstract：:Short-chain carboxylic acids (SCCA; C < or = 5; e.g., lactic acid, propionic acid, butyric acid) are metabolic by-products of bacterial metabolism which accumulate in the gingival crevice, and exhibit significant biological activity, including the ability to alter gene expression. It has been hypothesized that among t...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1996.tb00604.x
更新日期：1996-08-01 00:00:00
abstract：AIM:The current investigation evaluated changes in levels and proportions of 40 bacterial species in subgingival plaque samples during, immediately after and up to 1 year after metronidazole or amoxicillin therapy combined with SRP. METHOD:After baseline clinical and microbiological monitoring, 17 adult periodontitis ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1034/j.1600-051x.2001.028007597.x
更新日期：2001-07-01 00:00:00
abstract：AIM:To investigate the association of the Periodontal Risk Assessment (PRA) model categories with periodontitis recurrence and tooth loss during supportive periodontal therapy (SPT) and to explore the role of patient compliance. MATERIAL AND METHODS:In a retrospective cohort, PRA was performed for 160 patients after a...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2009.01508.x
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:Information about the agreement between intra-oral (I-O) and panoramic (OPG) radiographs is limited. AIMS:: (1) To assess the agreement between I-Os and OPGs for direct measurements of the distance between the cemento-enamel junction (CEJ) and the alveolar bone level (BL) as well as the proportional values ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1034/j.1600-051x.2003.00379.x
更新日期：2003-09-01 00:00:00
abstract：:A trial was conducted to compare the effectiveness of povidone iodine and chlorhexidine gluconate with buffered peroxyborate in the treatment of acute ulcerative gingivitis. After 20 patients had entered the trial and 11 had required additional therapy with metronidazole to control their symptoms, the study was termin...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-051x.1978.tb01919.x
更新日期：1978-11-01 00:00:00
abstract：OBJECTIVES:This study evaluated the dimensional ridge alteration in a buccal-bone-deficient extraction socket, and ridge regeneration following socket grafting accompanied by recombinant human bone morphogenetic protein 2 (rhBMP-2) or a collagen membrane covering. MATERIAL AND METHODS:In five beagle dogs, entire bucca...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.12414
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:Peri-implantitis is common in patients with dental implants. We performed a single-blinded longitudinal randomized study to assess the effects of mechanical debridement on the peri-implant microbiota in peri-implantitis lesions. MATERIALS AND METHODS:An expanded checkerboard DNA-DNA hybridization assay enco...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2010.01561.x
更新日期：2010-06-01 00:00:00
abstract：:The present clinical trial was designed to evaluate the effects of a bioactive glass, Perioglas, in the treatment of periodontal intrabony defects. 20 patients, 23-55 years of age (44 sites), with intrabony defects completed the 1-year study. Teeth with furcation involvement were excluded. After completion of initial ...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1600-051x.1997.tb00205.x
更新日期：1997-06-01 00:00:00
abstract：AIM:To quantify reduced and oxidized glutathione (GSH and GSSG) levels in gingival crevicular fluid (GCF) of periodontitis patients pre-therapy (versus periodontally healthy controls) and ascertain whether successful non-surgical therapy alters glutathione levels. MATERIALS AND METHODS:Thirty-second GCF samples (6/sub...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2009.01504.x
更新日期：2010-01-01 00:00:00
abstract：:This paper summarizes the rationale for the application of microbiology in the management of destructive periodontal diseases. The subgingival microbiota in patients with severe periodontitis is complex and contains high numbers of obligate anaerobic bacteria as well as facultative micro-organisms. It has become clear...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,评审
doi：10.1111/j.1600-051x.1991.tb02308.x
更新日期：1991-07-01 00:00:00
abstract：OBJECTIVE:We have investigated whether a purified immunomodulatory water soluble beta-1,3/1,6-glucan isolated from the cell wall of Bakers yeast, Saccharomyces cerevisiae, would influence the progression of ligature-induced periodontal disease, and to modulate accompanying cytokine and hypothalamic-pituitary-adrenal (H...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2005.00672.x
更新日期：2005-04-01 00:00:00
abstract：:Although it is established that the immunosuppressant cyclosporin-A (CsA) and calcium antagonists [Nifedipine (Nif) and Diltiazem (Dz)] can independently induce gingival enlargement, little has been documented on the significance of the salivary CsA levels and the combined effect of CsA and a calcium antagonist upon g...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1993.tb00360.x
更新日期：1993-04-01 00:00:00
abstract：:A scanning electron microscopic study of the brushing surface of 17 different types of commercial toothbrushes with natural and nylon bristles was conducted on new unused brushes as well as on 65 brushes used from 1 month up to 1 year, once, twice or three times a day, with various brushing techniques. Natural swine o...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1982.tb01231.x
更新日期：1982-03-01 00:00:00
abstract：:In the present two-year longitudinal investigation, the progression of periodontal disease was assessed after 1 year from the baseline examination in 38 dentate subjects and after 2 years in 22 dentate subjects with a mean duration of 18 years of insulin-dependent diabetes mellitus. The diabetics, aged 35 to 56 years ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1993.tb00338.x
更新日期：1993-03-01 00:00:00
abstract：:This investigation compares the Periotron 6000, Periotron 600, and ninhydrin area systems for quantifying gingival fluid. All systems have highly significant (p less than 0.001) linear relationships between measurements and fluid volumes. Additional curvilinear components have virtually no clinically significant impli...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1984.tb01313.x
更新日期：1984-11-01 00:00:00
abstract：AIM:Aim of this study was to investigate the influence of an anti-inflammatory diet on different parameters in patients with gingivitis. MATERIALS AND METHODS:Thirty patients were randomly allocated to an experimental and a control group stratified by their plaque values. The experimental group had to change to a diet...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jcpe.13094
更新日期：2019-04-01 00:00:00
abstract：AIMS:The objective of this study was to characterize the inhibitory effects of Weissella cibaria isolates on volatile sulphur compounds (VSC) production both in vitro and in vivo. MATERIAL AND METHODS:We isolated and identified three hydrogen peroxide-generating lactobacilli from children's saliva, and assessed their ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2006.00893.x
更新日期：2006-03-01 00:00:00
abstract：:A case of juvenile periodontitis is described where biopsy material taken from a lower right incisor during periodontal surgery revealed plaque-derived bacteria present within the periodontal connective tissue. The gingival connective tissue contained an inflammatory infiltrate which exhibited a profound loss of colla...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1982.tb01225.x
更新日期：1982-01-01 00:00:00
abstract：AIMS:Both, vitamin D3 and human periodontal ligament cells (hPDLCs) possess immunosuppressive properties, but their combined effect on immune cells has never been investigated. Here, we analysed the impact of vitamin D3 on the immunosuppressive properties of hPDLCs towards CD4+ T lymphocytes. MATERIAL AND METHODS:Allo...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.13283
更新日期：2020-06-01 00:00:00
