Abstract:
AIM:The aim of this study was to determine the prevalence and the structure of the leukotoxin promoter region of Actinobacillus actinomycetemcomitans in an ethnic Chinese population. METHOD:Subgingival plaque samples were collected from 42 patients with moderate to advanced periodontitis and 50 periodontally healthy patients. A. actinomycetemcomitans was detected directly from the crude subgingival plaque by PCR using leukotoxin gene specific primers. The presence of A. actinomycetemcomitans was determined by a single 285 bp PCR amplicon. RESULTS:A. actinomycetemcomitans was found to be present in the subgingival plaque of 68 out of a total of 92 patients examined (74%). 29 out of the 42 periodontitis patients tested were carriers of A. actinomycetemcomitans (69%). Among the periodontally healthy patients studied, 39 out of 50 subjects possessed the bacteria (78%). PCR analysis of the promoter region of the ltx operon revealed that none of the 42 moderate to advanced periodontitis patients examined harboured A. actinomycetemcomitans strains with the JP2-like promoter of the ltx operon, known to enhance leukotoxin expression. 2 out of the 27 advanced periodontitis patients clinically diagnosed as suffering from rapidly progressive periodontitis were found to be carriers of the mildly toxic strain of A. actinomycetemcomitans with the characteristic 652-like promoter. CONCLUSIONS:The high prevalence of A. actinomycetemcomitans, regardless of whether the subgingival samples were analysed from patients with healthy or diseased periodontium suggests that this bacterial species is part of the normal oral flora of ethnic Chinese. Our preliminary results also suggested that subjects who harboured the mildly toxic strain of A. actinomycetemcomitans were potentially susceptible to aggressive forms of periodontitis.
journal_name
J Clin Periodontoljournal_title
Journal of clinical periodontologyauthors
Tan KS,Woo CH,Ong G,Song KPdoi
10.1034/j.1600-051x.2001.028009886.xkeywords:
subject
Has Abstractpub_date
2001-09-01 00:00:00pages
886-90issue
9eissn
0303-6979issn
1600-051Xpii
cpe280912journal_volume
28pub_type
杂志文章abstract:BACKGROUND/AIMS:This study aimed to investigate the concentration of the cytokine interleukin (IL)-1beta and its receptor antagonist IL-1ra in gingival crevicular fluid (GCF) in patients with adult periodontitis who were heavy smokers compared with non-smokers. METHOD:GCF samples were collected from two groups of subj...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2003.300107.x
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:The aim of this prospective, randomized, controlled clinical study was to compare the effectiveness of a newly developed ultrasonic device to that of scaling and root planing for non-surgical periodontal treatment. MATERIAL AND METHODS:Thirty-eight patients with moderate to advanced chronic periodontal dise...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-051X.2004.00496.x
更新日期:2004-06-01 00:00:00
abstract::A total of 383 students, ages 12-16, were examined clinically to determine periodontal attachment loss by a trained examiner, utilizing standard techniques. 70 of these were selected, for whom bitewing radiographs were available for assessment of early alveolar bone loss by 2 radiologists and a general dentist, utiliz...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1985.tb00922.x
更新日期:1985-03-01 00:00:00
abstract::In four beagle dogs, periodontal tissue breakdown was experimentally induced around the upper left premolars (P1, P2 and P3). Wooden probes were inserted mesially and distally to each premolar. Six different probing forces were used in each dog. Microscopic examination showed: 1) the presence of an intact layer of epi...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1980.tb01975.x
更新日期:1980-08-01 00:00:00
abstract::The purpose of this cross-sectional epidemiological study was to determine the prevalence of pathologic tooth migration (PTM) among periodontal patients and to investigate the relationship and degree of association between PTM and the following factors: bone loss, tooth loss, gingival inflammation according to the gin...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1997.tb00217.x
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate the association between serum lipids and periodontal infection and the role of serum lipids in the association between body weight and periodontal infection. MATERIAL AND METHODS:The Health 2000 Health Examination Survey, which included 8028 subjects aged 30 or older l...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2008.01331.x
更新日期:2008-12-01 00:00:00
abstract::The purpose of this study was to evaluate the sensitivity of 4 clinical techniques used in detecting early plaque during a period of dietary sucrose restriction and during a period of sucrose supplementation. The accumulation of plaque during experimental periods of 3 h, 6 h and 18 h was recorded in a group of 38 dent...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1986.tb00862.x
更新日期:1986-08-01 00:00:00
abstract:AIMS:Long-term oral chronic inflammatory process is closely related to systemic inflammation, which is a main mechanism involved in non-alcoholic fatty liver disease (NAFLD). Tooth loss could reflect the accumulation of oral local inflammation, implying that number of missing teeth may associate with NAFLD. This study ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12929
更新日期:2018-08-01 00:00:00
abstract:AIMS:To compare a monotherapy of Er:YAG laser debridement (ERL), wavelength 2940 nm, with mechanical scaling and root planing (SRP) for the treatment of chronic periodontitis using clinical and patient-centred outcomes. METHODS:Twenty-eight participants had two randomly assigned quadrants treated with ERL and two with...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-051X.2012.01873.x
更新日期:2012-06-01 00:00:00
abstract:AIM:The aim of this study was to compare peri-implant conditions between fully edentulous (FES) and partially edentulous subjects (PES). MATERIAL AND METHODS:A systematic review was conducted. The MEDLINE, EMBASE and COCHRANE databases were searched for publications up to January 1st 2012. Studies reporting on the ble...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/jcpe.12013
更新日期:2013-03-01 00:00:00
abstract:AIM:The aim of this study was to identify long-term prognostic factors for the loss of molars with different degrees of furcation involvement (FI) during supportive periodontal therapy (SPT). METHODS:Three hundred and seventy-nine compliant subjects with 2373 molars at baseline were retrospectively assessed. After non...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12460
更新日期:2015-10-01 00:00:00
abstract:AIM:To evaluate the clinical outcomes of the use of a xenogeneic collagen matrix (CM) in combination with the coronally advanced flap (CAF) in the treatment of localized recession defects. MATERIAL & METHODS:In a multicentre single-blinded, randomized, controlled, split-mouth trial, 90 recessions (Miller I, II) in 45 ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/jcpe.12019
更新日期:2013-01-01 00:00:00
abstract:AIMS:To evaluate the associations between serum inflammatory biomarkers and periodontal inflammation in subjects with type 1 diabetes mellitus (T1DM). Our hypothesis was that local host responses may be modulated by the serum inflammatory mediators. MATERIAL AND METHODS:Plaque, bleeding on probing and probing pocket d...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2011.01731.x
更新日期:2011-08-01 00:00:00
abstract:AIM:This case-control study investigates the relationship of stress and anxiety with periodontal clinical characteristics. METHOD:Seventy-nine selected patients (mean age 46.8+/-8 years) were assigned to three groups in accordance with their levels of probing pocket depth (PPD): control group (PPD< or =3 mm, n=22), te...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2003.10271.x
更新日期:2003-05-01 00:00:00
abstract:AIM:To evaluate the 1-year outcome of Minimally Invasive Single Implant Treatment (M.I.S.I.T.) based on ridge preservation and contour augmentation in patients with a high aesthetic risk profile. MATERIALS AND METHODS:Periodontally healthy non-smoking patients with a failing tooth in the anterior maxilla (15-25) were ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12384
更新日期:2015-04-01 00:00:00
abstract::Early plaque growth and plaque topography were studied in 15 young adults with a healthy periodontium during a 4-day period of no oral hygiene. After perfect tooth-cleaning, the recolonisation of the buccal surfaces of 48 teeth (front teeth and premolars) was recorded at the start and after 6, 12, 24, 30, 36, 48, 54, ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1989.tb01655.x
更新日期:1989-05-01 00:00:00
abstract:AIM:The aim of this systematic review was to evaluate whether maternal periodontal disease treatment (MPDT) can reduce the incidence of preterm birth (PB) and/or low birth weight (LBW). METHODS:The Cochrane Central Register of Controlled Trials, MEDLINE and EMBASE were searched for entries up to October 2010 without r...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1600-051X.2011.01761.x
更新日期:2011-10-01 00:00:00
abstract:AIM:To evaluate whether obesity affects the subgingival microbial composition of patients with periodontal health or chronic periodontitis (CP). MATERIALS AND METHODS:Based on periodontal parameters, body mass index and waist-hip ratio, 166 patients were allocated into one of the following groups: Normal weight (NW) p...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12634
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:This retrospective study described the pattern of bone loss around teeth with endodontic posts in periodontitis patients, and compared it with contra-lateral teeth without posts. MATERIAL AND METHODS:From full-mouth radiographic surveys of 146 periodontitis patients (> or =35 years), 194 roots with endodont...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2009.01465.x
更新日期:2009-11-01 00:00:00
abstract::13 patients with untreated adult periodontitis (AP) were compared to 8 subjects free of periodontal disease (H) with respect to plaque index (PlI), gingival index (GI), probing depth (PD) and differential counts of subgingival bacterial morphotypes from a pooled sample of 6 surfaces with the greatest probing depth. Se...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1986.tb00878.x
更新日期:1986-09-01 00:00:00
abstract::The aim of the present study was to characterize the eventual presence and molecular forms of gelatinase/type IV collagenase activities in gingival crevicular fluid (GCF) and saliva in different forms of periodontitis; patients with clinically healthy periodontium served as controls. Enzyme activities were monitored e...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1994.tb00272.x
更新日期:1994-01-01 00:00:00
abstract::A review of the literature was made, focusing on experimental designs used in clinical studies for assessment of the efficacy of interdental cleaning aids with regard to plaque removal and the prevention of caries and gingivitis. After careful consideration of the pros and cons of published procedures, an experimental...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051x.1993.tb00695.x
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to conduct a review on quality of reporting on descriptive studies in implant dentistry using the STROBE Statement and to analyse possible changes in quality of reporting on descriptive studies in implant dentistry over time. MATERIAL AND METHODS:A hand search to select descriptive...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051X.2011.01834.x
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:Investigate the association between the frequency of alcohol consumption and periodontitis. Moreover, evaluate the influence of biological, behavioural, and social risk variables in this association. METHODS:Sample was comprised by 542 subjects of both genders, 35-55 years of age, who underwent a complete pe...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2011.01809.x
更新日期:2012-02-01 00:00:00
abstract:AIM:The purpose of this study was to investigate the relationship between cigarette smoking and the serum levels of folic acid, vitamin B(12) and some haematological variables in patients with periodontal disease. PATIENTS AND METHODS:The study base consisted of 88 volunteer patients with periodontal disease, includin...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2006.01003.x
更新日期:2006-12-01 00:00:00
abstract::The periodontal status of 85 12-18 year-old Finnish adolescents with insulin-dependent diabetes mellitus (IDDM) and their paired, age- and sex-matched healthy controls was assessed clinically and radiographically. The clinical examination consisted of plaque index, gingival index (GI), retentive calculus index, WHO co...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1989.tb01028.x
更新日期:1989-11-01 00:00:00
abstract:BACKGROUND:A polymorphism in the promoter region of the transforming growth factor beta-1 (TGF-beta1) gene was described at position -509. This polymorphism represents a C-to-T base exchange, which creates a YY1 consensus sequence in an area involved with down transcription regulation. This polymorphism has been associ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2003.00323.x
更新日期:2003-06-01 00:00:00
abstract::A cross-sectional study was designed to evaluate the periodontal status of 85 12-18 year-old French adolescents with insulin-dependent diabetes (IDDM) and 38 healthy controls in the same age group. The clinical examination consisted of plaque control and gingival inflammation evaluation and probing attachment level. T...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1992.tb01710.x
更新日期:1992-10-01 00:00:00
abstract::The purpose of this study was to assess the effect of rinsing and topical application of sanguinarine on labial surface plaque accumulation, compared with topically applied water, and compared with rinsing with chlorhexidine, while refraining from all oral hygiene measures for 5 days. Color photographs of the disclose...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1988.tb01002.x
更新日期:1988-02-01 00:00:00
abstract:BACKGROUND:Bone morphogenetic proteins (BMPs) have shown considerable promise as a therapeutic agent to enhance periodontal regeneration although the optimal characteristics of a suitable release system are not known. AIM:The aim of this study was to compare the effects of slow and fast degrading gelatin carriers on B...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2001.028004340.x
更新日期:2001-04-01 00:00:00