当前位置： SCI文献检索 > JOURNAL OF CLINICAL PERIODONTOLOGY期刊下所有文献 > Evidence grade associating periodontitis with preterm birth and/or low birth weight: II: a systematic review of randomized trials evaluating the effects of periodontal treatment.

Evidence grade associating periodontitis with preterm birth and/or low birth weight: II: a systematic review of randomized trials evaluating the effects of periodontal treatment.

Abstract：

AIM:The aim of this systematic review was to evaluate whether maternal periodontal disease treatment (MPDT) can reduce the incidence of preterm birth (PB) and/or low birth weight (LBW). METHODS:The Cochrane Central Register of Controlled Trials, MEDLINE and EMBASE were searched for entries up to October 2010 without restrictions regarding the language of publication. Only randomized-controlled clinical trials (RCTs) that evaluated the effect of MPDT on birth term and birth weight were included. The search was conducted by two independent reviewers and random-effects meta-analyses were conducted methodically. RESULTS:Thirteen RCTs provided data, but only five trials were considered to be at a low risk of bias. The results of eight studies (61.5%) showed that MPDT may reduce the incidence of PB and/or LBW. However, the results of all meta-analyses showed contrasting results for PB [RR: 0.88 (95% CI: 0.72, 1.09)], LBW [RR: 0.78 (95% CI: 0.53, 1.17)] and PB/LBW [RR: 0.52 (95% CI: 0.08, 3.31)]. CONCLUSION:The results of this review show that MPDT did not decrease the risk of PB and/or LBW; however, the influence of specific aspects that were not investigated (disease diagnosis, extension and severity and the success of MPDT) should be evaluated by future RCTs.

journal_name

J Clin Periodontol

journal_title

Journal of clinical periodontology

authors

Chambrone L,Pannuti CM,Guglielmetti MR,Chambrone LA

doi

10.1111/j.1600-051X.2011.01761.x

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

902-14

issue

10

eissn

0303-6979

issn

1600-051X

journal_volume

38

pub_type

杂志文章,meta分析,评审

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