当前位置： SCI文献检索 > JOURNAL OF CLINICAL PERIODONTOLOGY期刊下所有文献 > Treatment of gingival recession defects with a coronally advanced flap and a xenogeneic collagen matrix: a multicenter randomized clinical trial.

Treatment of gingival recession defects with a coronally advanced flap and a xenogeneic collagen matrix: a multicenter randomized clinical trial.

Abstract：

AIM:To evaluate the clinical outcomes of the use of a xenogeneic collagen matrix (CM) in combination with the coronally advanced flap (CAF) in the treatment of localized recession defects. MATERIAL & METHODS:In a multicentre single-blinded, randomized, controlled, split-mouth trial, 90 recessions (Miller I, II) in 45 patients received either CAF + CM or CAF alone. RESULTS:At 6 months, root coverage (primary outcome) was 75.29% for test and 72.66% for control defects (p = 0.169), with 36% of test and 31% of control defects exhibiting complete coverage. The increase in mean width of keratinized tissue (KT) was higher in test (from 1.97 to 2.90 mm) than in control defects (from 2.00 to 2.57 mm) (p = 0.036). Likewise, test sites had more gain in gingival thickness (GT) (0.59 mm) than control sites (0.34 mm) (p = 0.003). Larger (≥3 mm) recessions (n = 35 patients) treated with CM showed higher root coverage (72.03% versus 66.16%, p = 0.043), as well as more gain in KT and GT. CONCLUSIONS:CAF + CM was not superior with regard to root coverage, but enhanced gingival thickness and width of keratinized tissue when compared with CAF alone. For the coverage of larger defects, CAF + CM was more effective.

journal_name

J Clin Periodontol

journal_title

Journal of clinical periodontology

authors

Jepsen K,Jepsen S,Zucchelli G,Stefanini M,de Sanctis M,Baldini N,Greven B,Heinz B,Wennström J,Cassel B,Vignoletti F,Sanz M

doi

10.1111/jcpe.12019

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

82-9

issue

1

eissn

0303-6979

issn

1600-051X

journal_volume

40

pub_type

杂志文章,多中心研究,随机对照试验

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