Abstract：
AIMS:To evaluate the associations between serum inflammatory biomarkers and periodontal inflammation in subjects with type 1 diabetes mellitus (T1DM). Our hypothesis was that local host responses may be modulated by the serum inflammatory mediators. MATERIAL AND METHODS:Plaque, bleeding on probing and probing pocket depth (PD) were examined in 80 T1DM subjects at the baseline and in 58 subjects 8 weeks after periodontal therapy. The levels of glycosylated haemoglobin, serum interleukin (IL)-6, ultrasensitive C-reactive protein and the lipid profile were measured at the baseline and after therapy. Stratification of the sample separately by smoking and body mass index (BMI) was performed. Adjusted associations between the levels of systemic biomarkers and periodontal parameters were studied using multiple regression models. RESULTS:The level of serum IL-6 was associated with the extent of bleeding and PD≥4 mm at the baseline in non-smokers and in subjects with BMI≤26 kg/m(2). These associations were also evident after periodontal therapy. Subjects with a high after-therapy IL-6 level presented poorer periodontal healing than those with a low level. CONCLUSIONS:The observed associations may be considered to be suggestive of a modulatory effect of IL-6 on host responses in T1DM subjects.
journal_name
J Clin Periodontoljournal_title
Journal of clinical periodontologyauthors
Passoja A,Knuuttila M,Hiltunen L,Karttunen R,Niemelä O,Raunio T,Vainio O,Hedberg P,Tervonen Tdoi
10.1111/j.1600-051X.2011.01731.xsubject
Has Abstractpub_date
2011-08-01 00:00:00pages
687-93issue
8eissn
0303-6979issn
1600-051Xjournal_volume
38pub_type
杂志文章abstract：OBJECTIVES:The primary aim was to address the following focused question: What is the clinical effect of laser application compared with mechanical debridement in non-surgical periodontal therapy in patients with chronic periodontitis? A secondary aim was to survey the relevant literature in relation to safety of laser...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1600-051X.2008.01259.x
更新日期：2008-09-01 00:00:00
abstract：AIM:The objective of this prospective study was to assess clinical and patient-centred outcomes of aesthetic crown lengthening surgery for the treatment of altered passive eruption. MATERIALS AND METHODS:Twenty-two patients were treated and followed up for 6 months. The evaluated clinical parameters included, among ot...
journal_title：Journal of clinical periodontology
pub_type：
doi：10.1111/jcpe.12482
更新日期：2015-12-01 00:00:00
abstract：:Studies during the last 20 years have indicated that enamel-related proteins are involved in the formation of cementum. In the present article, this relation is further explored. Attention is called to the fact that coronal acellular extrinsic fiber cementum is formed on the enamel surface in a number of species. The ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,评审
doi：10.1111/j.1600-051x.1997.tb00247.x
更新日期：1997-09-01 00:00:00
abstract：AIM:We aimed to investigate the association of periodontitis and oral hygiene indicators with changes in blood lipid parameters in a nationwide, population-based cohort in a longitudinal setting. MATERIALS AND METHODS:We included nationwide health screening program participants who underwent oral health examination in...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.13373
更新日期：2020-12-01 00:00:00
abstract：:A double-blind, randomised, 6-month clinical trial with parallel group design in 149 patients with gingivitis was conducted to study the efficacy and safety of delmopinol hydrochloride 2 mg/ml (0.2% w/v, Decapinol Mouthwash) used for partly supervised mouthrinsing in comparison with chlorhexidine digluconate 2 mg/ml (...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1600-051x.1998.tb02516.x
更新日期：1998-09-01 00:00:00
abstract：INTRODUCTION:Chronic kidney disease (CKD) is associated with significant morbidity and mortality. There is a need to identify novel and modifiable risk factors in such patients. The periodontal component of the Renal Impairment In Secondary Care (RIISC) study aims to evaluate the association between chronic periodontit...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章
doi：10.1111/jcpe.12263
更新日期：2014-07-01 00:00:00
abstract：AIM:The purpose of this study was to investigate the relationship between cigarette smoking and the serum levels of folic acid, vitamin B(12) and some haematological variables in patients with periodontal disease. PATIENTS AND METHODS:The study base consisted of 88 volunteer patients with periodontal disease, includin...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2006.01003.x
更新日期：2006-12-01 00:00:00
abstract：:A cross-sectional study was designed to evaluate the periodontal status of 85 12-18 year-old French adolescents with insulin-dependent diabetes (IDDM) and 38 healthy controls in the same age group. The clinical examination consisted of plaque control and gingival inflammation evaluation and probing attachment level. T...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1992.tb01710.x
更新日期：1992-10-01 00:00:00
abstract：AIM:This prospective multicenter randomized controlled clinical trial was designed to compare the clinical outcomes of papilla preservation flap surgery with or without the application of a guided tissue regeneration (GTR)/bone replacement material. MATERIALS AND METHODS:One hundred and twenty-four patients with advan...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1111/j.1600-051X.2004.00562.x
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVES:We aimed to assess how the 2018 and 1999 classifications of periodontal diseases reflect (a) patients' characteristics, (b) disease severity/extent/progression and (c) tooth loss (TL) during observation period. METHODS:A total of 251 patients were followed over 21.8 ± 6.2 years. For the 1999 classification,...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.13157
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:B-cells are prominent immune cells in established periodontitis lesions. Tumour necrosis factor superfamily (TNFSF) cytokines play roles in supporting B-cell function as well as bone re-modelling. The influence of smoking on factors that support B-cell function in periodontitis remains unclear. AIM:To inves...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.12134
更新日期：2013-09-01 00:00:00
abstract：AIMS:The objective of this study was to characterize the inhibitory effects of Weissella cibaria isolates on volatile sulphur compounds (VSC) production both in vitro and in vivo. MATERIAL AND METHODS:We isolated and identified three hydrogen peroxide-generating lactobacilli from children's saliva, and assessed their ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2006.00893.x
更新日期：2006-03-01 00:00:00
abstract：AIMS:Patient-reported outcomes have attracted interest as there has been a shift from clinician-centric endpoints. This qualitative study aimed to develop an understanding of the psychosocial impact of periodontitis and its treatment. MATERIALS AND METHODS:Fourteen adults were asked to document their experiences of un...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.13309
更新日期：2020-08-01 00:00:00
abstract：AIM:Small incision surgery has become routine in many areas of medicine but has not been widely accepted in periodontal therapy. A videoscope to assist minimally invasive surgery (MIS) has been developed. The clinical outcomes from MIS performed using this videoscope (V-MIS) are reported. MATERIALS AND METHODS:Patient...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.12294
更新日期：2014-09-01 00:00:00
abstract：AIM:The current investigation evaluated changes in levels and proportions of 40 bacterial species in subgingival plaque samples during, immediately after and up to 1 year after metronidazole or amoxicillin therapy combined with SRP. METHOD:After baseline clinical and microbiological monitoring, 17 adult periodontitis ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1034/j.1600-051x.2001.028007597.x
更新日期：2001-07-01 00:00:00
abstract：:The aim of the present study was to compare periodontal healing after successive removal of periodontal tissue components, from the alveolar bone to the dentin surface. The prevailing tissue reaction when adhering PDM was left on the exposed roots was that most of the bone tissue that had been removed from the buccal ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1993.tb01753.x
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVES:The aim of the present study was to compare the combination therapy of deep intrabony periodontal defects using an Er:YAG laser (ERL) and enamel matrix protein derivative (EMD) to scaling and root planing+ ethylenediaminetetraacetic acid (EDTA)+EMD. MATERIAL AND METHODS:Twenty-two patients with chronic peri...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1034/j.1600-051x.2003.00412.x
更新日期：2003-11-01 00:00:00
abstract：AIM:To present the 6-year results of a randomized-controlled clinical trial evaluating guided tissue regeneration (GTR) combined with or without deproteinized bovine bone mineral (DBBM) in intrabony defects. MATERIAL & METHODS:In each of 45 patients, one defect was treated with GTR combined with DBBM hydrated in salin...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2009.01520.x
更新日期：2010-02-01 00:00:00
abstract：:The present study was designed to examine if alveolar bone, located adjacent to a root surface deprived of its periodontal ligament and cementum layer, can stimulate the reformation of a connective tissue attachment. The maxillary and mandibular incisors in 3 monkeys were extracted. Immediately after tooth extraction,...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1984.tb01306.x
更新日期：1984-01-01 00:00:00
abstract：AIM:The aim of this study was to compare short- and long-term root coverage and aesthetic outcomes of the coronally advanced flap (CAF) alone or in combination with a connective tissue graft (CTG) for the treatment of multiple gingival recessions. METHODS:Fifty patients with multiple (≥2) adjacent gingival recessions ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jcpe.12224
更新日期：2014-04-01 00:00:00
abstract：INTRODUCTION:The remit of this group was to update the knowledge base on periodontal diseases and health. MATERIAL AND METHODS:The literature was systematically searched and critically reviewed in five specific topics. RESULTS:Prevalence of periodontitis: The data suggest a trend towards a lower prevalence of periodo...
journal_title：Journal of clinical periodontology
pub_type： 共识发展会议,杂志文章
doi：10.1111/j.1600-051X.2008.01278.x
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:The purpose of the present study was to assess the relation between clinical parameters and concentrations of the key (IL-1beta, TNF-alpha, IL-2, IFN-gamma, IL-4, IL-10) cytokines, important in the initiation and progression of periodontal diseases, within inflamed gingival tissues and serum samples from pati...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1046/j.0303-6979.2003.00425.x
更新日期：2003-12-01 00:00:00
abstract：BACKGROUND:Cross-arch bridges are used to stabilize teeth for patients with reduced periodontal support. Little is known about technical or biological complications, whether teeth and implants can be combined in this type of bridge and the long-term effects on tooth loss. MATERIALS AND METHODS:All patients treated in ...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-051X.2009.01528.x
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:Quaternary ammonium compounds constitute a large group of antibacterial chemicals with a potential for inhibiting plaque and gingivitis. One compound, benzalkonium chloride (BC), may be of value, although there is a dearth of evidence to support efficacy. The aim of this study was to measure the ability of 2...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1034/j.1600-051x.2000.027001037.x
更新日期：2000-01-01 00:00:00
abstract：:The present investigation attempted to determine if the pattern of past periodontal destruction could be concisely summarized, and related to other clinical and microbiological parameters. 61 subjects between the ages of 12 and 61 years with destructive periodontal disease were evaluated at 6 sites per tooth for redne...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1986.tb00856.x
更新日期：1986-07-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to describe self-reported oral health, oral hygiene habits, and frequency of visits to a dentist among pregnant women in Kuwait. MATERIAL AND METHODS:A cross-sectional study with an anonymous structured questionnaire was distributed among 650 pregnant women during May-June 2003, wh...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2005.00770.x
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:Although a growing body of evidence indicates that oral irrigation with water has therapeutic benefits in periodontitis, the mechanisms of action have not been elucidated. The aims of this study were: (1) to analyze the effects of oral irrigation (Water Pik Oral Irrigator) on the clinical signs of adult peri...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章
doi：10.1034/j.1600-051x.2000.027002134.x
更新日期：2000-02-01 00:00:00
abstract：:One child and one adult with severe periodontitis were investigated for relevant systemic factors and predominant periodontal pocket bacteria. The child had a chronic neutropenia, the adult late yaws, a chronic iron deficiency and possibly rheumatoid arthritis. The predominant organisms in both pocket floras were gram...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1983.tb02202.x
更新日期：1983-03-01 00:00:00
abstract：:A longitudinal study was conducted on 106 patients attending a dental school and undergoing periodontal treatment, to assess the relationship between some commonly used periodontal indices and the time taken to treat periodontal disease. The data were analysed by assessing the times taken for examination motivation, s...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：
更新日期：1979-06-01 00:00:00
abstract：OBJECTIVE:This paper reports a meta-analysis of studies that have investigated the effect of scaling and root planing on periodontal probing depth and attachment loss. MATERIAL AND METHODS:The criteria used for inclusion of studies were as follows: root planing and scaling alone was one of the primary treatment arms; ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,meta分析
doi：10.1034/j.1600-051x.2002.291102.x
更新日期：2002-11-01 00:00:00
