当前位置： SCI文献检索 > JOURNAL OF CLINICAL PERIODONTOLOGY期刊下所有文献 > Guided tissue regeneration combined with a deproteinized bovine bone mineral (Bio-Oss) in the treatment of intrabony periodontal defects: 6-year results from a randomized-controlled clinical trial.

Guided tissue regeneration combined with a deproteinized bovine bone mineral (Bio-Oss) in the treatment of intrabony periodontal defects: 6-year results from a randomized-controlled clinical trial.

Abstract：

AIM:To present the 6-year results of a randomized-controlled clinical trial evaluating guided tissue regeneration (GTR) combined with or without deproteinized bovine bone mineral (DBBM) in intrabony defects. MATERIAL & METHODS:In each of 45 patients, one defect was treated with GTR combined with DBBM hydrated in saline (DBBM-) or gentamicin sulphate (DBBM+) or with GTR alone. Clinical parameters were recorded pre-surgery, at 1 and 6 years postsurgery. RESULTS:Thirty-six patients/33 teeth were available for the 6-year control. Statistically significant clinical improvements were observed for all treatments. Clinical attachment level (CAL) gain averaged 2.5 mm (DBBM-), 4.1 mm (DBBM+), and 3.0 mm (GTR) at 1 year postsurgery, and remained stable over 5 additional years (2.3, 4.1, and 2.7 mm, respectively). Treatment did not appear to influence residual probing depths (PDs) or CAL gains at 6 years postsurgery, or the extent of PD and CAL change from 1 to 6 years, and did not associate with sites losing CAL during follow-up. No association of grafting with sites showing CAL gain >or=4 mm at the 1- or 6-year control was observed. CONCLUSION:The improvements in periodontal conditions obtained after GTR treatment with or without the adjunct use of DBBM can be preserved on a long-term basis.

journal_name

J Clin Periodontol

journal_title

Journal of clinical periodontology

authors

Stavropoulos A,Karring T

doi

10.1111/j.1600-051X.2009.01520.x

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

200-10

issue

2

eissn

0303-6979

issn

1600-051X

pii

CPE1520

journal_volume

37

pub_type

杂志文章,随机对照试验

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