Abstract:
:Nonalcoholic fatty liver disease (NAFLD) is one of the main chronic noncommunicable diseases in Westernized societies; its worldwide prevalence has doubled during the last 20 years. NAFLD has serious health implications not only for adults, but also for children. However, pediatric NAFLD is not only an important global problem in itself, but it is likely to be associated with increases in comorbidities, such as metabolic syndrome and cardiovascular diseases. There are several differences between NAFLD in children and adults, and it is not clear whether the disease observed in children is the initial phase of a process that progresses with age. The increasing prevalence of pediatric NAFLD has serious implications for the future adult population requiring appropriate action. Studies of NAFLD progression, pathogenesis, and management should evaluate disease phenotypes in children and follow these over the patient's lifetime. We review the similarities and differences of NAFLD between children and adults.
journal_name
Gastroenterologyjournal_title
Gastroenterologyauthors
Nobili V,Alisi A,Newton KP,Schwimmer JBdoi
10.1053/j.gastro.2016.03.009subject
Has Abstractpub_date
2016-06-01 00:00:00pages
1798-810issue
8eissn
0016-5085issn
1528-0012pii
S0016-5085(16)00355-3journal_volume
150pub_type
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