Estrogen enhances dietary cholesterol induction of saturated bile in the hamster.

abstract：:Detailed porphyrin analysis and additional ultrastructural abnormalities of liver cells are described in a patient with features of Rotor's syndrome. Normal values of porphyrin precursors, delta-aminolevulinic acid and porphobilinogen, and porphyrins were found in plasma, urine, and erythrocytes. However, fecal porphy...

journal_title：Gastroenterology

authors： Evans J,Lefkowitch J,Lim CK,Billing B

更新日期：1981-12-01 00:00:00

abstract：:Experiments were designed to test the hypothesis that alterations of intestinal motility accompany enteric helminth infections. Motility was measured in rats during the intestinal phase of infection with the nematode Trichinella spiralis by following the transit of radioactive chromium through the gut. Intraduodenal c...

journal_title：Gastroenterology

authors： Castro GA,Badial-Aceves F,Smith JW,Dudrick SJ,Weisbrodt NW

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND & AIMS:We performed a prospective, randomized, controlled study to compare the combination of esomeprazole and clopidogrel vs clopidogrel alone in preventing recurrent peptic ulcers in patients with atherosclerosis and a history of peptic ulcers. We also investigated the effects of esomeprazole on the antipl...

journal_title：Gastroenterology

authors： Hsu PI,Lai KH,Liu CP

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND & AIMS:Biliary epithelial cells are the target of numerous immune-mediated liver diseases, yet their role in pathogenesis remains unclear because of difficulties in obtaining pure preparations. The aim of this study was to establish pure clones of immortalized murine intrahepatic biliary epithelial cells. M...

journal_title：Gastroenterology

authors： Paradis K,Le ON,Russo P,St-Cyr M,Fournier H,Bu D

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND & AIMS:Probiotics can reduce symptoms of irritable bowel syndrome (IBS), but little is known about their effects on psychiatric comorbidities. We performed a prospective study to evaluate the effects of Bifidobacterium longum NCC3001 (BL) on anxiety and depression in patients with IBS. METHODS:We performed ...

journal_title：Gastroenterology

authors： Pinto-Sanchez MI,Hall GB,Ghajar K,Nardelli A,Bolino C,Lau JT,Martin FP,Cominetti O,Welsh C,Rieder A,Traynor J,Gregory C,De Palma G,Pigrau M,Ford AC,Macri J,Berger B,Bergonzelli G,Surette MG,Collins SM,Moayyedi P,

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND/AIMS:Cytokines are thought to be important in mediating tissue damage in inflammatory bowel disease (IBD). Many of the in vivo activities of tumor necrosis factor alpha (TNF-alpha) match the changes found in IBD, but its importance is controversial. METHODS:A sensitive, reverse hemolytic plaque assay was us...

journal_title：Gastroenterology

authors： Breese EJ,Michie CA,Nicholls SW,Murch SH,Williams CB,Domizio P,Walker-Smith JA,MacDonald TT

更新日期：1994-06-01 00:00:00

abstract：:The role of the endothelium-derived vasodilator, nitric oxide, as a mediator of the increase in gastric mucosal blood flow and as a modulator of the acid secretory response induced by pentagastrin was investigated in the anesthetised rat. Intravenous administration of the selective inhibitor of endogenous nitric oxide...

journal_title：Gastroenterology

authors： Pique JM,Esplugues JV,Whittle BJ

更新日期：1992-01-01 00:00:00

abstract：:Obese subjects are prone to supersaturated bile, which is maintained or increased during weight loss. In this report, two related studies were carried out on obese subjects to investigate effects of bile acid feeding on biliary lipid metabolism before and during weight reduction. In one study, chenodeoxycholic acid (...

journal_title：Gastroenterology

authors： Mok HY,von Bergmann K,Crouse JR,Grundy SM

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND & AIMS:Standardized instruments are needed to assess the activity of eosinophilic esophagitis (EoE) and to provide end points for clinical trials and observational studies. We aimed to develop and validate a patient-reported outcome (PRO) instrument and score, based on items that could account for variations...

journal_title：Gastroenterology

authors： Schoepfer AM,Straumann A,Panczak R,Coslovsky M,Kuehni CE,Maurer E,Haas NA,Romero Y,Hirano I,Alexander JA,Gonsalves N,Furuta GT,Dellon ES,Leung J,Collins MH,Bussmann C,Netzer P,Gupta SK,Aceves SS,Chehade M,Moawad F

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:There is a significant interobserver and intraobserver variation in grading dysplasia in Barrett's metaplasia. New markers are needed to optimize the assessment of potential risk of cancer development in these patients. The aim of this study is to explore the use of p53 as a marker of neoplastic progression ...

journal_title：Gastroenterology

authors： Younes M,Lebovitz RM,Lechago LV,Lechago J

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND & AIMS:Trinitrobenzene sulfonic acid (TNBS)-induced colitis is a T-helper 1 (Th1) T cell-mediated inflammation that is rapidly reversed by administration of anti-interleukin (IL) 12. This study sought to define the mechanism of this curative effect. METHODS:Cells and tissue from mice with TNBS colitis recei...

journal_title：Gastroenterology

authors： Fuss IJ,Marth T,Neurath MF,Pearlstein GR,Jain A,Strober W

更新日期：1999-11-01 00:00:00

abstract：:The results of balloon dilatation of upper digestive tract stricture in 111 patients were evaluated. Eighty-eight patients had esophageal strictures and 23 had gastric or pyloric strictures. Thirty-six patients had strictures associated with previous operations. Twenty-two percent of the patients with esophageal stric...

journal_title：Gastroenterology

authors： Lindor KD,Ott BJ,Hughes RW Jr

更新日期：1985-09-01 00:00:00

abstract：:The aim of the present study was to characterize rat mucosal colonic cells harvested from the crypt continuum during differentiation and dimethylhydrazine-induced neoplasia. The collection of colonocytes was performed using a modified nonenzymatic isolation procedure based on Ca2+ chelation and gentle mechanical disso...

journal_title：Gastroenterology

authors： Schwartz B,Avivi C,Lamprecht SA

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND & AIMS:Empirical therapy has been proposed for initial management of dyspepsia. The aim of this study was to evaluate initial endoscopy, empirical therapy, and testing for Helicobacter pylori in the management of patients with a new onset of dyspepsia. METHODS:Decision analysis was used to compare the direc...

journal_title：Gastroenterology

authors： Silverstein MD,Petterson T,Talley NJ

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND & AIMS:During severe pancreatitis, interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha are produced in large quantities. The aim of this study was to determine whether either one plays a more dominant role and if their detrimental effects are additive. METHODS:Necrotizing pancreatitis was induced i...

journal_title：Gastroenterology

authors： Denham W,Yang J,Fink G,Denham D,Carter G,Ward K,Norman J

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND & AIMS:Although patients with inflammatory bowel disease (IBD) have reduced bone mass, there is controversy whether there is an increased risk of fracture. This study examines the risk of fracture and its predictors in patients with IBD. METHODS:In a primary care- based nested case-control study, 231,778 fr...

journal_title：Gastroenterology

authors： van Staa TP,Cooper C,Brusse LS,Leufkens H,Javaid MK,Arden NK

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND & AIMS:Development of pancreatic ductal adenocarcinoma (PDA) involves acinar to ductal metaplasia and genesis of tuft cells. It has been a challenge to study these rare cells because of the lack of animal models. We investigated the role of tuft cells in pancreatic tumorigenesis. METHODS:We performed studie...

journal_title：Gastroenterology

authors： DelGiorno KE,Chung CY,Vavinskaya V,Maurer HC,Novak SW,Lytle NK,Ma Z,Giraddi RR,Wang D,Fang L,Naeem RF,Andrade LR,Ali WH,Tseng H,Tsui C,Gubbala VB,Ridinger-Saison M,Ohmoto M,Erikson GA,O'Connor C,Shokhirev MN,Hah

更新日期：2020-11-01 00:00:00

abstract：:The effects of a variety of substances influencing the initiation of cyclic motor events at the gastroduodenal junction were studied in conscious sheep. A significant and long-lasting decrease in the frequency of cyclic events from approximately 100 min to 30-40 min was elicited by the intraduodenal bulb administratio...

journal_title：Gastroenterology

authors： Ruckebusch Y

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND & AIMS:Visceral hypersensitivity plays a major role in the pathophysiology of inflammatory bowel syndrome (IBS). Opioid kappa receptors on afferent nerves may modulate it and may be the target of new IBS treatments. The aim of this study was to evaluate the effects of fedotozine, a potent and selective kappa...

journal_title：Gastroenterology

authors： Delvaux M,Louvel D,Lagier E,Scherrer B,Abitbol JL,Frexinos J

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND & AIMS:De novo hepatitis B virus (HBV)-related hepatitis after chemotherapy results in high morbidity and mortality. We evaluate the clinical course of de novo HBV-related hepatitis after chemotherapy. METHODS:Two hundred forty-four consecutive hepatitis B surface antigen (HBsAg)-negative lymphoma patients ...

journal_title：Gastroenterology

authors： Hui CK,Cheung WW,Zhang HY,Au WY,Yueng YH,Leung AY,Leung N,Luk JM,Lie AK,Kwong YL,Liang R,Lau GK

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND AIMS:To influence host and disease phenotype, compositional microbiome changes, which have been demonstrated in patients with primary sclerosing cholangitis (PSC), must be accompanied by functional changes. We therefore aimed to characterize the genetic potential of the gut microbiome in PSC compared to ...

journal_title：Gastroenterology

authors： Kummen M,Thingholm LB,Rühlemann MC,Holm K,Hansen SH,Moitinho-Silva L,Liwinski T,Zenouzi R,Storm-Larsen C,Midttun Ø,McCann A,Ueland PM,Høivik ML,Vesterhus M,Trøseid M,Laudes M,Lieb W,Karlsen TH,Bang C,Schramm C,Fra

更新日期：2020-12-30 00:00:00

abstract：BACKGROUND & AIMS:Patients affected by familial adenomatous polyposis (FAP) are at increased risk of developing duodenal adenomas. In this study, cell proliferation of duodenal mucosa was analyzed to detect kinetic abnormalities related to cancer risk. METHODS:Duodenal biopsy specimens were collected in three groups o...

journal_title：Gastroenterology

authors： Santucci R,Volpe L,Zannoni U,Paganelli GM,Poggi B,Calabrese C,Biasco G

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND & AIMS:Proinflammatory cytokines alter function in enteric nerves, but little is known about underlying mechanisms. This study was designed to investigate the roles of prostanoids and of macrophage-like cells in cytokine-induced suppression of [3H]norepinephrine release from rat myenteric plexus. METHODS:Th...

journal_title：Gastroenterology

authors： Rühl A,Berezin I,Collins SM

更新日期：1995-12-01 00:00:00

abstract：DESCRIPTION:The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update is to review the available evidence and best practice advice statements regarding the use of endoscopic therapies in treating patients with non-variceal upper gastrointestinal bleeding. METHODS:This expert...

journal_title：Gastroenterology

authors： Mullady DK,Wang AY,Waschke KA

更新日期：2020-09-01 00:00:00

abstract：:Intramural pH of the gastric mucosa was measured using a microelectrode technique in rabbit gastric pouches under different secretory conditions and luminal acidity. Exposure of spontaneously secreting or metiamide-treated fundic pouches to a relatively high concentration of luminal acid. HCl 120 mM, for 60 min, led ...

journal_title：Gastroenterology

authors： Kivilaakso E,Fromm D,Silen W

更新日期：1978-10-01 00:00:00

abstract：:Canine ileal segments were luminally perfused with known amounts of polyethylene glycol (PEG), and samples obtained were freed of protein by a cold acetone (CA) method and assayed for PEG by trichloroacetic acid in the presence of calcium cations. This procedure was compared to the Barium salt (BaS) protein precipitat...

journal_title：Gastroenterology

authors： Buxton TB,Crockett JK,Moore WL 3rd,Moore WL Jr,Rissing JP

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND & AIMS:Patients with chronic hepatitis B virus (HBV) infection have a high risk for developing hepatocellular carcinoma (HCC). Patients with lower levels of hepatitis B surface antigen (HBsAg) have higher chances of losing HBsAg than those with high levels. However, little is known about whether higher level...

journal_title：Gastroenterology

authors： Tseng TC,Liu CJ,Yang HC,Su TH,Wang CC,Chen CL,Kuo SF,Liu CH,Chen PJ,Chen DS,Kao JH

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND & AIMS:High-carbohydrate diets with a high glycemic response may exacerbate the metabolic consequences of the insulin-resistance syndrome. The effect on the incidence of gallstone disease is not clear. METHODS:We examined the associations between high-carbohydrate diets with a high glycemic response and the...

journal_title：Gastroenterology

authors： Tsai CJ,Leitzmann MF,Willett WC,Giovannucci EL

更新日期：2005-07-01 00:00:00

abstract：:Thirty-five 1-day-old Pekin-Aylesbury ducks were inoculated intravenously or intraperitoneally with duck hepatitis B virus, and the time-course of infection was examined by Southern-blot, dot-blot, and in situ hybridization and by immunohistochemistry. Randomly scattered single infected hepatocytes were first seen on ...

journal_title：Gastroenterology

authors： Jilbert AR,Freiman JS,Burrell CJ,Holmes M,Gowans EJ,Rowland R,Hall P,Cossart YE

更新日期：1988-11-01 00:00:00

abstract：:Adverse effects associated with nonsteroidal antiinflammatory drug treatment are reported more commonly to regulatory authorities than the adverse effects of any other form of treatment. Epidemiologic evidence in general suggests a doubling or quadrupling of the risk of ulcer complications or death in recipients of su...

journal_title：Gastroenterology

authors： Langman MJ

更新日期：1989-02-01 00:00:00