Abstract:
:The results of balloon dilatation of upper digestive tract stricture in 111 patients were evaluated. Eighty-eight patients had esophageal strictures and 23 had gastric or pyloric strictures. Thirty-six patients had strictures associated with previous operations. Twenty-two percent of the patients with esophageal strictures had malignancies. Overall, 92% were successfully dilated, with a complication rate of 3%. Follow-up information was available in 95% of patients. Eighty-seven percent of living patients experienced symptomatic improvement, which lasted for a median period of 12 mo. Forty percent required a further procedure during the period of follow-up. We found no difference between esophageal strictures and gastric or pyloric strictures in success rate, complications, or need for further dilatation, although patients with esophageal strictures were more apt to have symptomatic improvement. Postoperative strictures responded as well as nonoperative strictures. Previously dilated strictures in patients with esophageal reflux were managed as successfully as strictures never before dilated. We found balloon dilatation of upper digestive tract stricture to be a safe, effective technique.
journal_name
Gastroenterologyjournal_title
Gastroenterologyauthors
Lindor KD,Ott BJ,Hughes RW Jrdoi
10.1016/0016-5085(85)90449-4subject
Has Abstractpub_date
1985-09-01 00:00:00pages
545-8issue
3eissn
0016-5085issn
1528-0012pii
0016-5085(85)90449-4journal_volume
89pub_type
杂志文章相关文献
GASTROENTEROLOGY文献大全abstract::A 22-yr-old woman with a 7-yr history of systemic lupus erythematosus presented with anasarca and a serum albumin of 0.8 g/dl. Renal and hepatic function were near normal; the major route of protein loss appeared to be the intestine. A full-thickness section of jejunum obtained at laparotomy demonstrated a severe, dif...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:
更新日期:1981-09-01 00:00:00
abstract::Hepatitis B virus (HBV) and hepatitis C virus (HCV) cause 1.3 million deaths annually. To prevent more than 7 million deaths by 2030, the World Health Organization set goals to eliminate HBV and HCV, defined as a 90% reduction in new infections and a 65% reduction in deaths, and prevent more than 7 million related dea...
journal_title:Gastroenterology
pub_type: 杂志文章,评审
doi:10.1053/j.gastro.2018.10.048
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND & AIMS:This study used a low lesion prevalence population reflective of the screening setting to estimate the sensitivity and specificity of computerized tomographic (CT) colonography for detection of colorectal polyps. METHODS:This prospective, blinded study comprised 703 asymptomatic persons at higher-tha...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1016/s0016-5085(03)00894-1
更新日期:2003-08-01 00:00:00
abstract::Intestinal mucosal biopsy immunoglobulin content in a patient with eosinophilia, allergic gastroenteropathy (atopy, food sensitivities, protein-losing enteropathy, iron deficiency anemia, and growth retardation), and hyperimmunoglobulinemia E (68,000 units) was compared with that of a control group and a group with eo...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:
更新日期:1979-09-01 00:00:00
abstract:BACKGROUND & AIMS:Helicobacter pylori is an important etiologic factor in the development of gastric cancer. The aim of this study was to analyze the role of H. pylori infections in the induction of mutagenic events in gastric epithelial cells. The effect of a high-salt diet as a genotoxic risk factor was also investig...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1016/s0016-5085(03)00266-x
更新日期:2003-05-01 00:00:00
abstract::To determine whether pancreatic polypeptide (PP) is a physiologic inhibitor of pancreatic secretion, we have studied the effects of normal rabbit serum and anti-PP serum on pancreatic secretion during infusion of a physiologic dose of PP or intragastric food instillation in dogs. Infusion of 180 pmol/kg X h of PP, pre...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1016/0016-5085(86)90263-5
更新日期:1986-06-01 00:00:00
abstract:BACKGROUND & AIMS:The effects of short-term antigenic activation of mast cells on the gastrointestinal tract have been well characterized, but little is known about the effects of long-term exposure to antigen on mucosal mast cell reactivity. The aim of this study was to determine the effects of long-term antigen expos...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1016/s0016-5085(96)70013-6
更新日期:1996-12-01 00:00:00
abstract::Gastrointestinal symptoms occur in a large number of patients with food allergies. Immediate hypersensitivity mechanisms may give rise to the nausea, vomiting, abdominal pain, and diarrhea experienced by these patients. However, there are limited human data about the pathophysiological basis for these symptoms. Most o...
journal_title:Gastroenterology
pub_type: 杂志文章,评审
doi:10.1016/0016-5085(92)90047-3
更新日期:1992-09-01 00:00:00
abstract::A case of enterogenous cysts of the duodenum in a 44-yr-old man complicated by duodenal obstruction and relapsing pancreatitis is presented. The cystic duodenal lesions were visualized by endoscopic retrograde cholangiopancreatography and for the first time by computed tomography and abdominal sonography. Thus, the di...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1016/0016-5085(85)90157-x
更新日期:1985-03-01 00:00:00
abstract::A prospective and randomized study was performed comparing pneumatic forceful dilatation and surgical esophagomyotomy as primary treatment of patients with achalasia of the esophagus. Eighteen dilated and 20 operated patients were studied before and after treatment with 1 patient lost. Clinical, radiologic, and manome...
journal_title:Gastroenterology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1981-04-01 00:00:00
abstract::To determine the frequency of a sustained remission and to assess the long-term prognosis of relapse and retreatment, 66 patients with severe hepatitis B surface antigen-negative chronic active hepatitis and prolonged follow-up after initial corticosteroid withdrawal (mean, 10 +/- 0.4 yr) were evaluated. Selection of ...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1016/0016-5085(87)90862-6
更新日期:1987-01-01 00:00:00
abstract::Using a newly developed radioimmunoassay for porcine gastrin-releasing peptide in plasma, we studied the pharmacokinetics of this peptide after infusing it into pigs at two dose levels. The disappearance of the peptide from plasma was characterized by two components, a fast one (t 1/2 1.4 min) and a slow one (t 1/2 6....
journal_title:Gastroenterology
pub_type: 杂志文章
doi:
更新日期:1984-08-01 00:00:00
abstract:BACKGROUND & AIMS:Approximately half of the families that fulfill Amsterdam criteria for Lynch syndrome or hereditary nonpolyposis colorectal cancer (HNPCC) do not have evidence of the germline mismatch repair gene mutations that define this syndrome and result in microsatellite instability (MSI). The carcinogenic path...
journal_title:Gastroenterology
pub_type: 杂志文章,多中心研究
doi:10.1053/j.gastro.2010.01.035
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND & AIMS:The mechanisms by which mutations in the familial intrahepatic cholestasis-1 gene cause Byler's disease (progressive familial intrahepatic cholestasis type 1) are unknown. METHODS:Interactions among the apical sodium-dependent bile acid transporter, the farnesoid X receptor (FXR), and familial intrah...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1053/j.gastro.2003.12.013
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND & AIMS:Cellular and molecular mechanisms of esophageal ulcer healing remain unexplored. We studied the sequential cellular events and the expression of keratinocyte growth factor (KGF) and its receptor (KGF-R) during the healing of experimental esophageal ulcers. METHODS:Esophageal ulcers were produced in r...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1053/gast.2002.31004
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND & AIMS:Spontaneous hepatitis B surface antigen (HBsAg) seroclearance is a rare event in patients with chronic hepatitis B virus infection. The aim of this study was to clarify the controversy on long-term prognosis following spontaneous HBsAg seroclearance using a large series of patients. METHODS:A total o...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1053/gast.2002.36026
更新日期:2002-10-01 00:00:00
abstract::Regional specific antibodies and gel permeation chromatography were used to analyze the molecular forms of motilin in the human gut and plasma and in the porcine gut. The same antibodies were also used for immunocytochemical localization of the cell of origin of motilin. Two main molecular forms of motilin were identi...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:
更新日期:1981-02-01 00:00:00
abstract::Two benzodiazepine-receptor partial inverse agonists (Ro 15-4513, Ro 15-3505) and one benzodiazepine-receptor antagonist (flumazenil) were administered to rats with hepatic encephalopathy due to acute liver ischemia. Significant improvement (P less than 0.002) of both the clinical grade of hepatic encephalopathy and t...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1016/0016-5085(91)90538-v
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND & AIMS:There is no clear and point for the response to treatment of gastrointestinal human cytomegalovirus (HCMV) disease. HCMV-DNA quantitation on gastrointestinal biopsy specimens has proven its value for the diagnosis of gastrointestinal HCMV disease in patients with acquired immunodeficiency syndrome (AI...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1053/gast.1996.v111.pm8690210
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND & AIMS:Among the human mucin complementary DNAs thus far identified, two (MUC5AC and MUC6) were cloned from stomach libraries. This study examines the distribution of MUC6 in normal tissues and compares it with that of MUC5AC as well as with the expression of Lewis blood group antigens. METHODS:Affinity-pur...
journal_title:Gastroenterology
pub_type: 评论,杂志文章
doi:10.1016/0016-5085(95)90379-8
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND & AIMS:Noninvasive methods are needed to identify clinically significant portal hypertension (CSPH) and esophageal varices (EVs) in patients with compensated cirrhosis. We looked for markers of the presence of CSPH and EVs in patients with cirrhosis. METHODS:We performed a cross-sectional study that include...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1053/j.gastro.2012.10.001
更新日期:2013-01-01 00:00:00
abstract::Intracerebroventricular prostaglandin E2 (PGE2) inhibits stimulated gastric acid secretion; however, the central site of action is unknown. Specific PGE2 binding sites have been localized to the ventromedial hypothalamic nucleus and central amygdala (A). The nuclear accumbens has been shown to play a role in central n...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1016/0016-5085(91)90198-t
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND & AIMS:Genetic factors are believed to affect risk for irritable bowel syndrome (IBS), but there have been no sufficiently powered and adequately sized studies. To identify DNA variants associated with IBS risk, we performed a genome-wide association study (GWAS) of the large UK Biobank population-based coho...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1053/j.gastro.2018.03.064
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND/AIMS:Hepatic glucuronidation is quantitatively the most important conjugation reaction by which an array of endogenous compounds and xenobiotics undergo biotransformation and detoxification. The active site of the uridine diphosphate (UDP) glucuronosyltransferases, which catalyze glucuronidation reactions, h...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1016/0016-5085(95)90023-3
更新日期:1995-01-01 00:00:00
abstract::Osteopenia in the form of osteoporosis is a common clinical problem associated with chronic cholestatic liver disease, and clinical morbidity from atraumatic fractures is increasing as more patients with PBC and PSC undergo successful liver transplantation. In the absence of symptomatic fractures, the clinical diagnos...
journal_title:Gastroenterology
pub_type: 杂志文章,评审
doi:10.1016/0016-5085(95)90033-0
更新日期:1995-01-01 00:00:00
abstract::In vivo and in vitro ultrasonic characteristics of gallstones were compared with stone size and composition with the aim of understanding the basis for these features. In vivo and in vitro ultrasonic features of the same stone were identical. Acoustic shadowing was not due to stone type, radiodensity, or calcium conte...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:
更新日期:1979-08-01 00:00:00
abstract::This report describes a 59-year-old woman, who, after an initial reaction to hydralazine, inadvertently took the drug again. She promptly developed symptoms of acute cholangitis--fever, right upper quadrant tenderness, obtundation, and hypotension. Cholecystectomy was performed and no obstruction or infection of the b...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:
更新日期:1984-11-01 00:00:00
abstract::In this review, we compared the outcome of 25 studies of experimentally induced pancreatitis in animals with 13 studies of human acute pancreatitis in which the same therapeutic agents were used (aprotinin, glucagon, 5-fluorouracil, somatostatin, peritoneal lavage). Whereas 81% of the animal studies had a positive out...
journal_title:Gastroenterology
pub_type: 临床试验,杂志文章,评审
doi:10.1016/0016-5085(87)90275-7
更新日期:1987-12-01 00:00:00
abstract:BACKGROUND & AIMS:Tumor necrosis factor alpha (TNF-alpha) release plays a pivotal role in the pathogenesis of liver injury induced by lipopolysaccharide (LPS) administration in D-galactosamine (GalN)-sensitized mice. Interleukin (IL) 10 is an anti-inflammatory cytokine that inhibits TNF-alpha synthesis and release both...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1053/gast.1996.v111.pm8780580
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND & AIMS:The early detection of colorectal cancer is desired because this cancer can be cured surgically if diagnosed early. The purpose of the present study was to determine the feasibility of a new methodology for isolating colonocytes from naturally evacuated feces, followed by cytology or molecular biology...
journal_title:Gastroenterology
pub_type: 杂志文章
doi:10.1053/j.gastro.2005.10.007
更新日期:2005-12-01 00:00:00