Periportal sinusoidal dilatation, inflammatory bowel disease, and the contraceptive pill.

Abstract:

:Two women, aged 19 and 28 yr, who had been on the contraceptive pill for at least 18 mo, developed abnormal levels of circulating liver enzymes, minimal hepatomegaly, and elevated erythrocyte sedimentation rate. Liver biopsy in both women showed a sinusoidal dilatation sparing the perihepatic venous regions. The liver function abnormality resolved on stopping the pill. Both patients also had clinically mild inflammatory bowel disease. The possibility of both liver and bowel abnormalities being effects of contraceptive steroids is discussed.

journal_name

Gastroenterology

journal_title

Gastroenterology

authors

Camilleri M,Schafler K,Chadwick VS,Hodgson HJ,Weinbren K

subject

Has Abstract

pub_date

1981-04-01 00:00:00

pages

810-5

issue

4

eissn

0016-5085

issn

1528-0012

pii

S0016508581000759

journal_volume

80

pub_type

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