Abstract：
:In eukaryotes, loss of cytoplasmic ribosomal proteins (RPs) results in a reduced growth rate and other phenotypic defects. The ability to transition from a unicellular budding yeast to a filamentous form is very important for biofilm formation and virulence in Candida albicans. Our recent study found that loss of the RPS41 (C2_10620W_A) gene but not its paralog RPS42 (C1_01640W_A) resulted in altered growth and filamentation changes in C. albicans, so we hypothesized that the RPS41 gene should play important roles in virulence and biofilm formation in this pathogen. We found that both virulence and the ability to form biofilms were defective due to deletion of the RPS41 gene. We also found that loss of the RPS41 gene increased sensitivity to hydrogen peroxide, and that hydrogen peroxide induced the expression of the RPS41 gene in a wild-type strain. These results suggested that the RPS41 gene plays important roles in C. albicans biofilm formation, virulence, and susceptibility to hydrogen peroxide.
journal_name
Curr Microbioljournal_title
Current microbiologyauthors
Lu H,Xiong J,Shang Q,Jiang Y,Cao Ydoi
10.1007/s00284-016-1019-7subject
Has Abstractpub_date
2016-06-01 00:00:00pages
783-7issue
6eissn
0343-8651issn
1432-0991pii
10.1007/s00284-016-1019-7journal_volume
72pub_type
杂志文章abstract：:The laccase gene lacD, cloned from a novel laccase-producing basidiomycete Trametes sp. 420, contained 2,052 base pairs (bp) interrupted by 8 introns. lacD displayed a relatively high homology with laccase genes from other white rot fungi, whereas the homology between lacD and laccase genes from plants, insects, or ba...
journal_title：Current microbiology
pub_type： 杂志文章
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journal_title：Current microbiology
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1007/s00284-014-0717-2
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journal_title：Current microbiology
pub_type： 杂志文章
doi：10.1007/s00284-015-0980-x
更新日期：2016-05-01 00:00:00
abstract：:A Gram-negative, short rod-shaped, gliding motile, and pale pink-pigmented bacterial strain, designated 15J9-9T, was isolated from the soil of Iho Tewoo Beach, Jeju Island, Korea, and characterized taxonomically using a polyphasic approach. Comparative 16S rRNA gene sequence analysis showed that strain 15J9-9T belonge...
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更新日期：2017-07-01 00:00:00
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journal_title：Current microbiology
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doi：10.1007/s00284-020-02075-3
更新日期：2020-10-01 00:00:00
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journal_title：Current microbiology
pub_type： 杂志文章
doi：10.1007/s00284-006-0116-4
更新日期：2006-09-01 00:00:00
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journal_title：Current microbiology
pub_type： 杂志文章
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更新日期：1996-08-01 00:00:00
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更新日期：2020-09-01 00:00:00
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journal_title：Current microbiology
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更新日期：2009-05-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00284-012-0243-z
更新日期：2013-01-01 00:00:00
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journal_title：Current microbiology
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更新日期：2019-06-01 00:00:00
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journal_title：Current microbiology
pub_type： 杂志文章
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更新日期：2020-08-01 00:00:00
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journal_title：Current microbiology
pub_type： 杂志文章
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更新日期：2019-11-01 00:00:00
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journal_title：Current microbiology
pub_type： 杂志文章
doi：10.1007/s00284-018-1553-6
更新日期：2018-11-01 00:00:00
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journal_title：Current microbiology
pub_type： 杂志文章
doi：10.1007/s00284-001-0004-x
更新日期：2002-05-01 00:00:00
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更新日期：2019-12-01 00:00:00
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journal_title：Current microbiology
pub_type： 杂志文章
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更新日期：2020-05-01 00:00:00
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更新日期：2009-01-01 00:00:00
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更新日期：2012-05-01 00:00:00
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更新日期：2005-09-01 00:00:00
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更新日期：2006-05-01 00:00:00
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更新日期：2010-03-01 00:00:00
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journal_title：Current microbiology
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更新日期：2020-03-01 00:00:00
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journal_title：Current microbiology
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更新日期：2018-10-01 00:00:00
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更新日期：2014-09-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/BF02602456
更新日期：1980-07-01 00:00:00
abstract：:Thymol (5-methyl-2-isopropylphenol) is a phenolic compound that is used to inhibit oral bacteria. Because little is known regarding the effects of this compound on ruminal microorganisms, the objective of this study was to determine the effects of thymol on growth and lactate production by the ruminal bacteria Strepto...
journal_title：Current microbiology
pub_type： 杂志文章
doi：10.1007/s002840010145
更新日期：2000-11-01 00:00:00
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journal_title：Current microbiology
pub_type： 杂志文章
doi：10.1007/BF01577379
更新日期：1993-04-01 00:00:00
