Leukotriene E4 is a full functional agonist for human cysteinyl leukotriene type 1 receptor-dependent gene expression.

abstract：:Endocannabinoids are amphiphilic molecules that play crucial neurophysiological functions acting as lipid messengers. Antagonists and knockdown of the classical CB1 and CB2 cannabinoid receptors do not completely abolish many endocannabinoid activities, supporting the idea of a mechanism independent of receptors whose...

journal_title：Scientific reports

authors： Medeiros D,Silva-Gonçalves LC,da Silva AM,Dos Santos Cabrera MP,Arcisio-Miranda M

更新日期：2017-01-27 00:00:00

abstract：:Glucokinase (GK), the hexokinase involved in glucosensing in pancreatic β-cells, is also expressed in arcuate nucleus (AN) neurons and hypothalamic tanycytes, the cells that surround the basal third ventricle (3V). Several lines of evidence suggest that tanycytes may be involved in the regulation of energy homeostasis...

journal_title：Scientific reports

authors： Uranga RM,Millán C,Barahona MJ,Recabal A,Salgado M,Martinez F,Ordenes P,Elizondo-Vega R,Sepúlveda F,Uribe E,García-Robles MLÁ

更新日期：2017-06-16 00:00:00

abstract：:Electrical contacts on the top surface of solar cells and light emitting diodes cause shadow losses. The phenomenon of extraordinary optical transmission through arrays of subwavelength holes suggests the possibility of engineering such contacts to reduce the shadow using plasmonics, but resonance effects occur only a...

journal_title：Scientific reports

authors： San Román E,Vitrey A,Buencuerpo J,Prieto I,Llorens JM,García-Martín A,Alén B,Chaudhuri A,Neumann A,Brueck SR,Ripalda JM

更新日期：2016-06-24 00:00:00

abstract：:Immune checkpoint inhibitors (ICIs) elicit antitumour effects by activating the host immunity and cause immune-related adverse events (irAEs). ICI-related interstitial lung disease (ICI-ILD) is a fatal irAE that is difficult to treat; moreover, its incidence is relatively higher in patients with lung cancer. Therefore...

journal_title：Scientific reports

authors： Okada N,Matsuoka R,Sakurada T,Goda M,Chuma M,Yagi K,Zamami Y,Nishioka Y,Ishizawa K

更新日期：2020-08-13 00:00:00

abstract：:Hydrophilic polymers have garnered much attention due to their critical roles in various applications such as molecular separation membranes, bio-interfaces, and surface engineering. However, a long-standing problem is that their mechanical properties usually deteriorate at high relative humidity (RH). Through the sim...

journal_title：Scientific reports

authors： Liu T,An QF,Zhao Q,Wu JK,Song YH,Zhu BK,Gao CJ

更新日期：2015-01-14 00:00:00

abstract：:Twisting light in both phase and intensity has recently drawn great interests in various fields related to light-matter interactions such as optical manipulation of particles and quantum entanglement of photons. Conventionally, bulky optical components are required to produce such twisted optical beams, which signific...

journal_title：Scientific reports

authors： Zhang Y,Yang X,Gao J

更新日期：2018-03-20 00:00:00

abstract：:Mesoporous silica nanoscale microsphere (MSNM), with a special morphology, high porosity, large pore volume and specific surface area, was successfully prepared and used as the matrix material of lauric acid (LA) to prepare a favorable shape-stabilized phase change material (LA/MSNM). The porous network structure of M...

journal_title：Scientific reports

authors： Zhang Z,Wang J,Tang X,Liu Y,Han Z,Chen Y

更新日期：2019-11-05 00:00:00

abstract：:Predicting regions at risk from introductions of non-native species and the subsequent invasions is a fundamental aspect of horizon scanning activities that enable the development of more effective preventative actions and planning of management measures. The Asian cyprinid fish topmouth gudgeon Pseudorasbora parva ha...

journal_title：Scientific reports

authors： Fletcher DH,Gillingham PK,Britton JR,Blanchet S,Gozlan RE

更新日期：2016-05-20 00:00:00

abstract：:Hallmarks of Retinitis Pigmentosa (RP), a family of genetic diseases, are a typical rod-cone-degeneration with initial night blindness and loss of peripheral vision, followed by decreased daylight sight and progressive visual acuity loss up to legal blindness. Great heterogeneity in nature and function of mutated gene...

journal_title：Scientific reports

authors： Gargini C,Novelli E,Piano I,Biagioni M,Strettoi E

更新日期：2017-07-18 00:00:00

abstract：:We aimed to investigate the diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in evaluating blunt abdominal trauma for patients presenting to the emergency department. Electronic search of Scopus and Pubmed was performed from inception to September 2016. Human studies investigating the diagnostic accuracy of ...

journal_title：Scientific reports

authors： Zhang Z,Hong Y,Liu N,Chen Y

更新日期：2017-06-30 00:00:00

abstract：:Thus far, underwater and underground positioning techniques have been limited to those using classical waves (sound waves, electromagnetic waves or their combination). However, the positioning accuracy is strongly affected by the conditions of media they propagate (temperature, salinity, density, elastic constants, op...

journal_title：Scientific reports

authors： Tanaka HKM

更新日期：2020-11-03 00:00:00

abstract：:Many aspects of song learning in songbirds resemble characteristics of speech acquisition in humans. Genetic, anatomical and behavioural parallels have most recently been extended with demonstrated similarities in hemispheric dominance between humans and songbirds: the avian higher order auditory cortex is left-latera...

journal_title：Scientific reports

authors： Chirathivat N,Raja SC,Gobes SM

更新日期：2015-06-22 00:00:00

abstract：:Pituitary adenylate cyclase activating polypeptide (PACAP) is a regulatory and cytoprotective neuropeptide, its deficiency implies accelerated aging in mice. It is present in the auditory system having antiapoptotic effects. Expression of Ca2+-binding proteins and its PAC1 receptor differs in the inner ear of PACAP-de...

journal_title：Scientific reports

authors： Fulop DB,Humli V,Szepesy J,Ott V,Reglodi D,Gaszner B,Nemeth A,Szirmai A,Tamas L,Hashimoto H,Zelles T,Tamas A

更新日期：2019-10-10 00:00:00

abstract：:The structural characterization correlated to the processing control of hierarchical structure of planar heterojunction perovskite layer is still incomplete due to the limitations of conventional microscopy and X-ray diffraction. This present study performed the simultaneously grazing-incidence small-angle scattering ...

journal_title：Scientific reports

authors： Huang YC,Tsao CS,Cho YJ,Chen KC,Chiang KM,Hsiao SY,Chen CW,Su CJ,Jeng US,Lin HW

更新日期：2015-09-04 00:00:00

abstract：:Slow disintegration and poor solubility are common problems facing the dispersible tablets of Traditional Chinese Medicine (TCM). In an early study, the research group found that co-grinding of extracts and silica could achieve a rapid disintegration effect, though the mechanism of this effect was not thoroughly eluci...

journal_title：Scientific reports

authors： Li P,Feng B,Jiang H,Han X,Wu Z,Wang Y,Lin J,Zhang Y,Yang M,Han L,Zhang D

更新日期：2018-07-09 00:00:00

abstract：:Older patients, especially those with malignancy, may have an increased risk of pulmonary embolism (PE). However, few studies have evaluated the clinical characteristics and prognosis of older patients. We evaluated the clinical characteristics, prognosis, and risk factors in older patients with lung cancer complicate...

journal_title：Scientific reports

authors： Junjun L,Pei W,Ying Y,Kui S

更新日期：2020-01-27 00:00:00

abstract：:An accurate knowledge of tissue optical properties (absorption coefficients, μa, and reduced scattering coefficients, μs') is critical for precise modeling of light propagation in biological tissue, essential for developing diagnostic and therapeutic optical techniques that utilize diffusive photons. A great number of...

journal_title：Scientific reports

authors： Hoshi Y,Tanikawa Y,Okada E,Kawaguchi H,Nemoto M,Shimizu K,Kodama T,Watanabe M

更新日期：2019-06-24 00:00:00

abstract：:El Niño-Southern Oscillation (ENSO), which is one of the main drivers of Earth's inter-annual climate variability, often causes a wide range of climate anomalies, and the advance prediction of ENSO is always an important and challenging scientific issue. Since a unified and complete ENSO theory has yet to be establish...

journal_title：Scientific reports

authors： Yan J,Mu L,Wang L,Ranjan R,Zomaya AY

更新日期：2020-05-15 00:00:00

abstract：:Recent decades have experienced the discovery of numerous complex materials. At the root of the complexity underlying many of these materials lies a large number of contending atomic- and largerscale configurations. In order to obtain a more detailed understanding of such systems, we need tools that enable the detecti...

journal_title：Scientific reports

authors： Ronhovde P,Chakrabarty S,Hu D,Sahu M,Sahu KK,Kelton KF,Mauro NA,Nussinov Z

更新日期：2012-01-01 00:00:00

abstract：:Enterovirus A89 (EV-A89) is a novel member of the EV-A species. To date, only one full-length genome sequence (the prototype strain) has been published. Here, we report the molecular identification and genomic characterization of a Chinese EV-A89 strain, KSYPH-TRMH22F/XJ/CHN/2011, isolated in 2011 from a contact of an...

journal_title：Scientific reports

authors： Fan Q,Zhang Y,Hu L,Sun Q,Cui H,Yan D,Sikandaner H,Tang H,Wang D,Zhu Z,Zhu S,Xu W

更新日期：2015-12-21 00:00:00

abstract：:The niacin receptor HCA2 is implicated in controlling inflammatory host responses with yet poorly understood mechanistic basis. We previously reported that HCA2 in A431 epithelial cells transduced Gβγ-protein kinase C- and Gβγ-metalloproteinase/EGFR-dependent MAPK/ERK signaling cascades. Here, we investigated the role...

journal_title：Scientific reports

authors： Shi Y,Lai X,Ye L,Chen K,Cao Z,Gong W,Jin L,Wang C,Liu M,Liao Y,Wang JM,Zhou N

更新日期：2017-02-10 00:00:00

abstract：:Biofilms are complex microbial communities that present serious contamination risks to our environment and health. In this study, atmospheric air plasma and airborne acoustic ultrasound technology were applied to inactivate Escherichia coli and Listeria innocua biofilms. Both technologies were efficient in controlling...

journal_title：Scientific reports

authors： Patange AD,Simpson JC,Curtin JF,Burgess CM,Cullen PJ,Tiwari BK

更新日期：2021-01-27 00:00:00

abstract：:This work describes a simple technique to produce porous ceramics with aligned porosity having very high permeability and specific surface area. SiOC-based compositions were processed from blends of three types of preceramic polymer and a catalyst, followed by curing and pyrolysis. The heating applied from the bottom ...

journal_title：Scientific reports

authors： Vakifahmetoglu C,Zeydanli D,Innocentini MD,Ribeiro FD,Lasso PR,Soraru GD

更新日期：2017-01-20 00:00:00

abstract：:We present axial plane optical microscopy (APOM) that can, in contrast to conventional microscopy, directly image a sample's cross-section parallel to the optical axis of an objective lens without scanning. APOM combined with conventional microscopy simultaneously provides two orthogonal images of a 3D sample. More im...

journal_title：Scientific reports

authors： Li T,Ota S,Kim J,Wong ZJ,Wang Y,Yin X,Zhang X

更新日期：2014-12-01 00:00:00

abstract：:The mitochondrial genome almost exclusively encodes a handful of transmembrane constituents of the oxidative phosphorylation (OXPHOS) system. Coordinated expression of these genes ensures the correct stoichiometry of the system's components. Translation initiation in mitochondria is assisted by two general initiation ...

journal_title：Scientific reports

authors： Kuzmenko A,Derbikova K,Salvatori R,Tankov S,Atkinson GC,Tenson T,Ott M,Kamenski P,Hauryliuk V

更新日期：2016-01-05 00:00:00

abstract：:The functionalization of graphene remains an important challenge for numerous applications expected by this fascinating material. To keep advantageous properties of graphene after modification or functionalization of its structure, local approaches are a promising road. A novel technique is reported here that allows p...

journal_title：Scientific reports

authors： Li H,Daukiya L,Haldar S,Lindblad A,Sanyal B,Eriksson O,Aubel D,Hajjar-Garreau S,Simon L,Leifer K

更新日期：2016-01-29 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is currently a global pandemic, and there are limited laboratory studies targeting pathogen resistance. This study aimed to investigate the effect of selected disinfection products and methods on the inactivation of SARS-CoV-2 in the laboratory. We...

journal_title：Scientific reports

authors： Xiling G,Yin C,Ling W,Xiaosong W,Jingjing F,Fang L,Xiaoyan Z,Yiyue G,Ying C,Lunbiao C,Liubo Z,Hong S,Yan X

更新日期：2021-01-28 00:00:00

abstract：:Multisensory integration is a powerful mechanism for constructing body awareness and key for the sense of selfhood. Recent evidence has shown that the specialised C tactile modality that gives rise to feelings of pleasant, affective touch, can enhance the experience of body ownership during multisensory integration. N...

journal_title：Scientific reports

authors： Panagiotopoulou E,Filippetti ML,Tsakiris M,Fotopoulou A

更新日期：2017-10-10 00:00:00

abstract：:Magnetic-charge ordering and corresponding magnetic/monopole phase transitions in spin ices are the emergent topics of condensed matter physics. In this work, we investigate a series of magnetic-charge (monopole) phase transitions in artificial square spin ice model using the conserved monopole density algorithm. It i...

journal_title：Scientific reports

authors： Xie YL,Du ZZ,Yan ZB,Liu JM

更新日期：2015-10-29 00:00:00

abstract：:Distinct regions of long-range genetic fixation in the human MHC region, known as conserved extended haplotypes (CEHs), possess unique genomic characteristics and are strongly associated with numerous diseases. While CEHs appear to be homogeneous by SNP analysis, the nature of fine variations within their genomic stru...

journal_title：Scientific reports

authors： Lam TH,Tay MZ,Wang B,Xiao Z,Ren EC

更新日期：2015-11-23 00:00:00