In vitro fertilization without ovarian stimulation: a simplified protocol applied in 80 cycles.

Abstract:

:Ovulation induction with various hormonal agents has become a standard component of in vitro fertilization (IVF) cycles to obtain multiple oocytes. Failure to anticipate the retrieval of more than two oocytes often results in cancellation of the cycle. In this study, we report our results in 80 unstimulated IVF cycles. Serum estradiol (E2) and pelvic ultra-sound monitoring were begun on day 9 of the cycle. Human chorionic gonadotropin (hCG) was administered when the E2 level exceeded 180 pg/mL and the dominant follicle was greater than 18 mm. Eighteen pregnancies were obtained (22.5%/cycle), and 14 (17.5%/cycle) are ongoing. We conclude that favorable results can be obtained from unstimulated IVF cycles, despite replacement of a single embryo.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Foulot H,Ranoux C,Dubuisson JB,Rambaud D,Aubriot FX,Poirot C

doi

10.1016/s0015-0282(16)60974-3

subject

Has Abstract

pub_date

1989-10-01 00:00:00

pages

617-21

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)60974-3

journal_volume

52

pub_type

杂志文章
  • Von Willebrand factor expression in endometrial endothelial cells in women with menorrhagia.

    abstract::This prospective study assessed von Willebrand factor (VWF) expression in the endometrium using immunohistochemical staining in women with menorrhagia with or without von Willebrand disease (VWD) compared with a control group of women with normal menstrual loss. Endometrial VWF expression is significantly lower in wom...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2010.02.055

    authors: Agarwal U,El Sheikh S,Kulkarni A,Baff D,Kadir RA

    更新日期:2010-11-01 00:00:00

  • Blastocoele expansion degree predicts live birth after single blastocyst transfer for fresh and vitrified/warmed single blastocyst transfer cycles.

    abstract:OBJECTIVE:To evaluate the independent effects of the degree of blastocoele expansion and re-expansion and the inner cell mass (ICM) and trophectoderm (TE) grades on predicting live birth after fresh and vitrified/warmed single blastocyst transfer. DESIGN:Retrospective study. SETTING:Reproductive medical center. PATI...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2015.12.014

    authors: Du QY,Wang EY,Huang Y,Guo XY,Xiong YJ,Yu YP,Yao GD,Shi SL,Sun YP

    更新日期:2016-04-01 00:00:00

  • Ovarian pregnancy after in vitro fertilization.

    abstract::We report a rare ovarian pregnancy after in vitro fertilization and transcervical embryo transfer. Ultrasound guidance of embryo transfer does not eliminate the risk of this potentially lethal complication. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.02.026

    authors: Trolice MP,Dozier SC

    更新日期:2008-02-01 00:00:00

  • Blastocyst culture and transfer: a step toward improved in vitro fertilization outcome.

    abstract:OBJECTIVE:To evaluate the efficacy of blastocyst culture and transfer in human in vitro fertilization (IVF) as compared to day 3 embryo transfer. DESIGN:Prospective randomized trial. SETTING:Private assisted reproduction unit. PATIENT(S):A total of 162 IVF patients were included in the day 3 embryo transfer (n = 82)...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0015-0282(01)02939-9

    authors: Karaki RZ,Samarraie SS,Younis NA,Lahloub TM,Ibrahim MH

    更新日期:2002-01-01 00:00:00

  • Heritability of dehydroepiandrosterone sulfate in women with polycystic ovary syndrome and their sisters.

    abstract:OBJECTIVE:To test the hypothesis that adrenal androgen (AA) secretion is an inherited trait in PCOS and that serum DHEAS concentrations, as a marker of AA secretion, will be correlated between women with PCOS and their sisters. DESIGN:Prospective case-control. SETTING:Tertiary care center. PATIENT(S):Sixty-two PCOS ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.05.045

    authors: Yildiz BO,Goodarzi MO,Guo X,Rotter JI,Azziz R

    更新日期:2006-12-01 00:00:00

  • Hormonal secretions in singleton pregnancies arising from the implantation of fresh or frozen embryos after oocyte donation in women with ovarian failure.

    abstract:OBJECTIVE:To determine whether levels of human chorionic gonadotropin (hCG), 17 beta-estradiol (E2), and progesterone (P) are different in the peri-implantation phase of fresh versus frozen embryos. DESIGN:Hormonal secretions were measured on days 9 and 11 after implantation and at 4, 5, and 6 weeks gestation. PATIEN...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0015-0282(16)54792-x

    authors: Salat-Baroux J,Cornet D,Alvarez S,Antoine JM,Mandelbaum J,Plachot M

    更新日期:1992-01-01 00:00:00

  • Effect of antifreeze protein supplementation in vitrification medium on mouse oocyte developmental competence.

    abstract:OBJECTIVE:To investigate the effect of antifreeze protein (AFP) supplementation during mouse oocyte vitrification on the survival, fertilization and embryonic development. DESIGN:Animal study. SETTING:University laboratory. ANIMAL(S):BDF-1 mice. INTERVENTION(S):In vivo-matured metaphase II oocytes were vitrified wi...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.08.023

    authors: Jo JW,Jee BC,Lee JR,Suh CS

    更新日期:2011-11-01 00:00:00

  • Comparison of microdissection testicular sperm extraction, conventional testicular sperm extraction, and testicular sperm aspiration for nonobstructive azoospermia: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To investigate the relative differences in outcomes among microdissection testicular sperm extraction (micro-TESE), conventional testicular sperm extraction (cTESE), and testicular sperm aspiration (TESA) in men with nonobstructive azoospermia. DESIGN:Systematic review and meta-analysis. SETTING:Outpatient ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.fertnstert.2015.07.1136

    authors: Bernie AM,Mata DA,Ramasamy R,Schlegel PN

    更新日期:2015-11-01 00:00:00

  • Expression of vascular endothelial growth factor messenger ribonucleic acid and protein in human preimplantation embryos.

    abstract::In contrast to a previous report by Krussel et al., with the inclusion of larger numbers of unfertilized oocytes and normal embryos and more sensitive immunofluorescence, this study shows that expression of vascular endothelial growth factor messenger ribonucleic acid can be detected from the oocyte to the blastocyst ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2005.11.047

    authors: Hwu YM,Chen CP,Li SH,Chen PW,Lee RK,Fleming S

    更新日期:2006-06-01 00:00:00

  • Twin tubal pregnancy: a rising complication?

    abstract:OBJECTIVE:To present four cases of twin tubal pregnancies and discuss possible etiologies. Twin tubal pregnancies are a rare event, with incidence rates estimated as 1 out of 725-1,580 of tubal pregnancies. DESIGN:Case series. SETTING:Department of obstetrics and gynecology at a tertiary health care facility. PATIEN...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2010.03.017

    authors: Svirsky R,Maymon R,Vaknin Z,Mendlovic S,Weissman A,Halperin R,Herman A,Pansky M

    更新日期:2010-10-01 00:00:00

  • Chlamydia antibody by enzyme-linked immunosorbent assay and associated severity of tubal factor infertility.

    abstract::We have evaluated the clinical utility of the serum chlamydial antibody value by ELISA in predicting the severity of tubal factor infertility quantified by the use of a previously reported pelvic scoring system. Significant differences in salpingitis scores, tubal occlusion scores, adhesion scores, and pelvic stages w...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)55579-4

    authors: Minassian SS,Wu CH

    更新日期:1992-12-01 00:00:00

  • Basal and stimulated secretion of cytokines by peritoneal macrophages in women with endometriosis.

    abstract:OBJECTIVE:To evaluate basal (constitutive) and stimulated synthesis of tumor necrosis factor alpha (TNF alpha), interleukin (IL)-8, IL-10 by peritoneal macrophages (PM) in women with endometriosis. DESIGN:Peritoneal macrophages were cultured in the presence or absence of lipopolysaccharide (LPS) for 24 hours. Peritone...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Rana N,Braun DP,House R,Gebel H,Rotman C,Dmowski WP

    更新日期:1996-05-01 00:00:00

  • Magnetic resonance imaging and serum CA-125 in evaluating patients with endometriomas prior to medical therapy.

    abstract:OBJECTIVE:To determine whether magnetic resonance imaging (MRI) and serum levels of CA-125 can be used to evaluate patients with endometriomas before initiating medical treatment. DESIGN:Comparative study before and after medical treatment. SETTING:Shimane Medical University Hospital, Izumo, Japan. PATIENTS:Eleven c...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0015-0282(16)58087-x

    authors: Takahashi K,Okada S,Okada M,Kitao M,Kaji Y,Sugimura K

    更新日期:1996-02-01 00:00:00

  • Tubal embryo transfer as a treatment for infertility due to male factor.

    abstract::Transvaginal follicular aspiration (TVA) with ultrasonically guided needles allows the transfer of in vitro generated embryos to the fallopian tubes (TET), performing only one surgical procedure in the process. Up to now, this approach has been used to treat 16 couples with infertility due to severe male factor. Folli...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)60136-x

    authors: Balmaceda JP,Gastaldi C,Remohi J,Borrero C,Ord T,Asch RH

    更新日期:1988-09-01 00:00:00

  • The relation of fertility and ovarian histology after bilateral ovarian wedge resection.

    abstract::The immediate and long term fertility after bilateral ovarian wedge resection in 53 women with clomiphene citrate-resistant hyperandrogenic chronic anovulation is related to the histology of the ovarian wedges. Patients with polycystic ovaries and hyperplastic stromal abnormalities had most spontaneous conceptions and...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)60845-2

    authors: Lappöhn RE,Bogchelman DH

    更新日期:1989-08-01 00:00:00

  • A randomized controlled trial of tubal flushing with lipiodol for unexplained infertility.

    abstract:OBJECTIVE:To test the hypothesis that, in couples with unexplained infertility, tubal flushing with an oil-soluble media (lipiodol) would increase the pregnancy rate within 6 months compared with expectant management. DESIGN:A prospective, randomized, controlled study in which couples were allocated to either a single...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0015-0282(01)02925-9

    authors: Nugent D,Watson AJ,Killick SR,Balen AH,Rutherford AJ

    更新日期:2002-01-01 00:00:00

  • Executive summary of the Stages of Reproductive Aging Workshop + 10: addressing the unfinished agenda of staging reproductive aging.

    abstract:OBJECTIVE:The aim of this article is to summarize the recommended updates to the 2001 Stages of Reproductive Aging Workshop (STRAW) criteria. The 2011 STRAW + 10 reviewed advances in understanding of the critical changes in hypothalamic-pituitary-ovarian function that occur before and after the final menstrual period. ...

    journal_title:Fertility and sterility

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1016/j.fertnstert.2012.01.128

    authors: Harlow SD,Gass M,Hall JE,Lobo R,Maki P,Rebar RW,Sherman S,Sluss PM,de Villiers TJ,STRAW + 10 Collaborative Group.

    更新日期:2012-04-01 00:00:00

  • The activity (calcium oscillator?) responsible for human oocyte activation after injection with round spermatids is associated with spermatid nuclei.

    abstract:OBJECTIVE:To compare the oocyte-activating ability of whole human round spermatids and their isolated nuclei. DESIGN:Prospective study using sibling oocytes from patients undergoing spermatid conception and intracytoplasmic sperm injection treatment cycles. SETTING:Private assisted reproduction laboratories and a uni...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(00)01598-3

    authors: Tesarik J,Mendoza C,Greco E

    更新日期:2000-12-01 00:00:00

  • HOXA10 mutations in congenital absence of uterus and vagina.

    abstract:OBJECTIVE:To analyze the HOXA10 genes in CAUV patients for mutations. Congenital absence of the uterus and vagina (CAUV) is the most extreme female reproductive tract developmental defect known. The HOXA10 gene is expressed in the developing and adult uterus. Female mice with loss-of-function Hoxa10 gene mutations have...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.03.033

    authors: Lalwani S,Wu HH,Reindollar RH,Gray MR

    更新日期:2008-02-01 00:00:00

  • Timing luteal support in assisted reproductive technology: a systematic review.

    abstract:OBJECTIVE:To summarize the available published randomized controlled trial data regarding timing of P supplementation during the luteal phase of patients undergoing assisted reproductive technology (ART). DESIGN:A systematic review. SETTING:Not applicable. PATIENT(S):Undergoing IVF. INTERVENTION(S):Different starti...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2014.12.125

    authors: Connell MT,Szatkowski JM,Terry N,DeCherney AH,Propst AM,Hill MJ

    更新日期:2015-04-01 00:00:00

  • Nicotine induces apoptosis in TM3 mouse Leydig cells.

    abstract:OBJECTIVE:To investigate whether nicotine-induced testicular toxicity involves the induction of apoptosis in Leydig cells. DESIGN:Cell study using cells of the TM3 cell line derived from mouse Leydig cells. SETTING:Academic research laboratory. INTERVENTION(S):Morphological and biochemical analyses for the detection...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2004.12.013

    authors: Kim KH,Joo KJ,Park HJ,Kwon CH,Jang MH,Kim CJ

    更新日期:2005-04-01 00:00:00

  • Percutaneous vasal sperm aspiration and intrauterine insemination for infertile males with anejaculation.

    abstract:OBJECTIVE:To explore the effectiveness of percutaneous vasal sperm aspiration (PVSA) in combination with intrauterine insemination (IUI) to treat infertile men with anejaculation. DESIGN:Clinical study. SETTING:Department of reproductive endocrinology and andrology of a family planning research clinic. PATIENT(S):Tw...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(02)04697-6

    authors: Qiu Y,Wang SM,Yang DT,Wang LG

    更新日期:2003-03-01 00:00:00

  • A randomized trial comparing the endometrial effects of daily subcutaneous administration of 25 mg and 50 mg progesterone in aqueous preparation.

    abstract:OBJECTIVE:To study the efficacy of a new P preparation in aqueous solution for subcutaneous injection for inducing the predecidual transformation of the endometrium. DESIGN:Prospective, single-blinded, randomized, parallel pilot trial. SETTING:University-affiliated clinical research center. PATIENT(S):Twenty-five re...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2013.05.029

    authors: de Ziegler D,Sator M,Binelli D,Leuratti C,Cometti B,Bourgain C,Fu YS,Garhöfer G

    更新日期:2013-09-01 00:00:00

  • Abdominal myomectomy for otherwise unexplained infertility.

    abstract::Twenty-three patients with otherwise unexplained infertility underwent abdominal myomectomy for the removal of subserous or intramural myomata. None were submucosal in location. Fifteen of these patients (65.2%) conceived. There were 18 term births in 13 patients. All but 1 patient conceived within the first year. The...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)49536-1

    authors: Rosenfeld DL

    更新日期:1986-08-01 00:00:00

  • Criteria for number of embryos to transfer: a committee opinion.

    abstract::Based on American Society for Reproductive Medicine (ASRM) and Society for Assisted Reproductive Technology data available for 2010, ASRM's guidelines for the number of embryos to be transferred in in vitro fertilization cycles have been further refined in continuing efforts to reduce the number of higher-order multip...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.fertnstert.2012.09.038

    authors: Practice Committee of the American Society for Reproductive Medicine and the Practice Committee of the Society for Assisted Reproductive Technology.

    更新日期:2013-01-01 00:00:00

  • Pharmacological stimulation of sperm motility in frozen and thawed testicular sperm using the dimethylxanthine theophylline.

    abstract:OBJECTIVE:To evaluate whether the use of theophylline improves sperm motility and treatment outcome in frozen-thawed testicular sperm extraction (TESE). DESIGN:Artificial sperm activation was offered to azoospermic patients between January and October 2010 in two different centers (identical lab conditions). SETTING:...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.08.041

    authors: Ebner T,Tews G,Mayer RB,Ziehr S,Arzt W,Costamoling W,Shebl O

    更新日期:2011-12-01 00:00:00

  • A prospective, randomized study of pregnancy rates after transuterotubal and intrauterine insemination.

    abstract:OBJECTIVE:To assess the relative efficacy, in terms of clinical pregnancy rates (PRs), of transuterotubal insemination versus the more traditional intrauterine insemination (IUI) procedure. DESIGN:Prospective, randomized, cross-over. SETTING:University-affiliated tertiary care center. PATIENTS:One hundred sixty infe...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Oei ML,Surrey ES,McCaleb B,Kerin JF

    更新日期:1992-07-01 00:00:00

  • Ethnic variation in estradiol metabolism in reproductive age Asian and white women treated with transdermal estradiol.

    abstract::Asian women have significantly higher serum E(2) levels during treatment with transdermal E(2) compared with white women. This finding suggests altered metabolic clearance of this steroid hormone. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.06.023

    authors: Huddleston HG,Rosen MP,Gibson M,Cedars MI,Fujimoto VY

    更新日期:2011-09-01 00:00:00

  • Induction of endometrial cycles and ovulation in a woman with combined 17alpha-hydroxylase/17,20-lyase deficiency due to compound heterozygous mutations on the p45017alpha gene.

    abstract:OBJECTIVE:To describe the case of a Japanese woman with combined 17alpha-hydroxylase/17,20-lyase deficiency (congenital adrenal hyperplasia type V) and to discuss possible therapeutic procedures in such patients. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 26-year-old woman with secondary amenorrhe...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(00)00500-8

    authors: Matsuzaki S,Yanase T,Murakami T,Uehara S,Nawata H,Yajima A

    更新日期:2000-06-01 00:00:00

  • Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity.

    abstract:OBJECTIVE:To evaluate the phenotype, proliferative, and differentiation capacities in vitro of stromal cells derived from peritoneal, ovarian, and deeply infiltrating endometriosis. DESIGN:Experimental study using phase contrast microscopy, immunocytochemistry, and functional bioassays. SETTING:University-based labor...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2005.08.046

    authors: Klemmt PA,Carver JG,Kennedy SH,Koninckx PR,Mardon HJ

    更新日期:2006-03-01 00:00:00