A prospective, randomized study of pregnancy rates after transuterotubal and intrauterine insemination.

Abstract:

OBJECTIVE:To assess the relative efficacy, in terms of clinical pregnancy rates (PRs), of transuterotubal insemination versus the more traditional intrauterine insemination (IUI) procedure. DESIGN:Prospective, randomized, cross-over. SETTING:University-affiliated tertiary care center. PATIENTS:One hundred sixty infertile patients underwent 414 inseminations with or without controlled ovarian hyperstimulation. INTERVENTIONS:All patients were randomized in their initial cycle to transuterotubal insemination or IUI then crossed-over in subsequent cycles (n = 191 total cycles of transuterotubal insemination and n = 223 total cycles of IUI). Transuterotubal insemination was performed initially with ultrasound guidance, and then a tactile technique was used for the last 6 months of the study. MAIN OUTCOME MEASURES:Clinical PRs and complications after both insemination methods. RESULTS:The clinical PR per treatment cycle was 7% (13/191) after transuterotubal insemination and 7% (16/223) after IUI. The overall PR per patient was 18% (29/160). The incidence of ectopic pregnancy was 1 in 191 for transuterotubal insemination cycles and 0 in 223 for IUI cycles. Other complications included 3 vasovagal episodes with transuterotubal insemination and 1 with IUI. There was no clinical evidence of tubal infection, trauma, or perforation in either group. CONCLUSION:Transuterotubal insemination did not appear to be associated with a higher PR when compared with IUI in this study. The potential for increased risk from complications related to the more invasive tubal technique does not appear to justify its use presently.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Oei ML,Surrey ES,McCaleb B,Kerin JF

keywords:

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

167-71

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)55155-3

journal_volume

58

pub_type

临床试验,杂志文章,随机对照试验
  • Environmental contaminants and pregnancy outcomes.

    abstract:OBJECTIVE:To review selected environmental, occupational, and other important risk factors for the following adverse pregnancy outcomes: low birth weight (LBW), intrauterine growth retardation (IUGR), and preterm delivery (PTD). DESIGN:The evidence is explored in greater detail for environmental tobacco smoke, drinkin...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2007.12.041

    authors: Windham G,Fenster L

    更新日期:2008-02-01 00:00:00

  • Forty years of IVF.

    abstract::This monograph, written by the pioneers of IVF and reproductive medicine, celebrates the history, achievements, and medical advancements made over the last 40 years in this rapidly growing field. ...

    journal_title:Fertility and sterility

    pub_type: 历史文章,杂志文章,评审

    doi:10.1016/j.fertnstert.2018.06.005

    authors: Niederberger C,Pellicer A,Cohen J,Gardner DK,Palermo GD,O'Neill CL,Chow S,Rosenwaks Z,Cobo A,Swain JE,Schoolcraft WB,Frydman R,Bishop LA,Aharon D,Gordon C,New E,Decherney A,Tan SL,Paulson RJ,Goldfarb JM,Brännström

    更新日期:2018-07-15 00:00:00

  • Follicular fluid levels of insulin-like growth factor I, insulin-like growth factor binding protein I, and ovarian steroids collected during ovum pick-up.

    abstract:OBJECTIVE:To evaluate interrelationships between levels of insulin-like growth factor I (IGF-I), insulin-like growth factor binding protein (IGFBP-I), and ovarian steroids in late preovulatory follicular fluid (FF) after pituitary desensitization with GnRH agonist and controlled ovarian hyperstimulation. DESIGN:Follic...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)57179-9

    authors: Chang SY,Hsieh KC,Wang HS,Soong YK

    更新日期:1994-12-01 00:00:00

  • Protein O-carboxylmethyltransferase in spermatozoa from normal and infertile men.

    abstract::In confirmation of several reports, suspensions of normal washed human spermatozoa exposed to a nonionic detergent exhibited considerable activity of the enzyme protein O-carboxylmethyltransferase (PCM), which catalyzes the methyl esterification of carboxyl groups of dicarboxylic amino acid residues in proteins. Vario...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Hatch R,Harvey SE,Williams-Ashman HG

    更新日期:1985-04-01 00:00:00

  • Identification of a uteroglobin-like antigen in human uterine washings.

    abstract::A uteroglobin-like molecule was detected with a sensitive radioimmunoassay for rabbit uteroglobin in the uterine washings of women. This antigen was detectable only in small amounts in the uterine washings obtained from women in the late luteal phase or proliferative phase, but was detected in large amounts in uterine...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)49399-4

    authors: Cowan BD,North DH,Whitworth NS,Fujita R,Shumacher EK,Mukherjee AB

    更新日期:1986-06-01 00:00:00

  • Modification of germinal epithelium ischemia by perfusion.

    abstract::Three groups of dogs underwent testicular ischemia for a 3-hour period. Group I (10 animals) was not subsequently perfused. Group II (10 animals) underwent subsequent perfusion by a new in vivo reversible method via the internal spermatic artery with heparinized saline. Group III (5 animals) underwent perfusion with S...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)42924-9

    authors: Stiles RE Jr,Klugo RC,Farah RN,Cerny JC

    更新日期:1977-11-01 00:00:00

  • Results of artificial insemination at home by the partner with cryopreserved donor semen: a randomized study.

    abstract::The use of cryopreserved semen offers the possibility of home insemination by the instructed partner. A comparative study was designed whereby participants were randomly allocated to use home or clinic insemination for six cycles. If no pregnancy had occurred after six cycles, the site of insemination was switched to ...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0015-0282(16)59956-7

    authors: Hogerzeil HV,Hamerlynck JV,van Amstel N,Nagelkerke NJ,Lammes FB

    更新日期:1988-06-01 00:00:00

  • The International Endogene Study: a collection of families for genetic research in endometriosis.

    abstract:OBJECTIVE:The aim of the International Endogene Study is to discover genes that influence susceptibility to endometriosis. DESIGN:The study brings together two research groups based in Australia and the United Kingdom that independently have been collecting families for linkage analysis and candidate gene studies. Bot...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(02)03341-1

    authors: Treloar S,Hadfield R,Montgomery G,Lambert A,Wicks J,Barlow DH,O'Connor DT,Kennedy S,International Endogene Study Group.

    更新日期:2002-10-01 00:00:00

  • Introduction: IVF's 40th world birthday.

    abstract::Forty years ago this month the first baby was born as a result of in vitro fertilization (IVF). The arrival of Louise Brown brought with her a new hope and possibility for the many men and women across the global struggling with infertility who previously had very few options for treatment or family building. In this ...

    journal_title:Fertility and sterility

    pub_type: 历史文章

    doi:10.1016/j.fertnstert.2018.05.017

    authors: Niederberger C,Pellicer A

    更新日期:2018-07-01 00:00:00

  • Tests of prolactin secretion in the diagnosis of hyperprolactinemic states: nomifensine and domperidone.

    abstract::Forty-one subjects with hyperprolactinemia underwent testing on separate occasions with nomifensine, an indirectly acting dopamine agonist, and domperidone, a dopamine receptor-blocking agent. Nomifensine (200 mg orally) did not significantly modify plasma levels of prolactin (PRL) in 17 subjects in whom the existence...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)45314-8

    authors: Massara F,Genazzani AR,Camanni F,De Leo V,Molinatti GM,Müller EE

    更新日期:1981-02-01 00:00:00

  • Increased expression of endothelin-1 and its receptors in varicocele: an immunohistochemical study.

    abstract::We hypothesized that diminished endothelin 1 (ET-1) expression at the spermatic vein wall level might be responsible for the development of varicocele. However, immunohistochemical evaluation of spermatic and control vein samples from 55 patients with varicocele showed overexpression of ET-1 and its receptors ETA and ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.04.062

    authors: Gyftopoulos K,Chondrogianni C,Papadaki H

    更新日期:2011-06-30 00:00:00

  • Müllerian-inhibiting substance in follicular fluid and serum: a comparison of patients with tubal factor infertility, polycystic ovary syndrome, and endometriosis.

    abstract:OBJECTIVE:To determine Müllerian inhibiting substance (MIS) levels in follicular fluid (FF) and sera of IVF patients. DESIGN:Prospective study. SETTING:Fertility center. PATIENT(S):Sixty-six patients: 20 with tubal factor infertility, 17 with polycystic ovary syndrome (PCOS), and 29 with endometriosis. INTERVENTION...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(97)81417-3

    authors: Fallat ME,Siow Y,Marra M,Cook C,Carrillo A

    更新日期:1997-05-01 00:00:00

  • Nelson's syndrome in pregnancy.

    abstract::A patient with Nelson's syndrome whose pregnancy was complicated by symptomatic enlargement of an ACTH-producing pituitary tumor was described. Emergency ablative surgery was performed with successful outcomes for both mother and infant. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)48932-6

    authors: Surrey ES,Chang RJ

    更新日期:1985-10-01 00:00:00

  • Strategies to minimize discomfort during diagnostic hysterosalpingography with disposable balloon catheters: a randomized placebo-controlled study with oral nonsteroidal premedication.

    abstract:OBJECTIVE:To assess whether oral administration of 100 mg of nimesulide reduces pain during or after a hysterosalpingography (HSG) performed with disposable balloon catheters. DESIGN:Prospective, randomized, placebo-controlled study. SETTING:Reproductive Centre, Department of Obstetrics and Gynaecology, University of...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2007.07.1302

    authors: Anserini P,Delfino F,Ferraiolo A,Remorgida V,Menoni S,De Caro G

    更新日期:2008-09-01 00:00:00

  • Gonadotropin-releasing hormone agonists for the preservation of ovarian function among women with breast cancer who did not use tamoxifen after chemotherapy: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To determine whether concurrent use of GnRH agonists with chemotherapy preserves ovarian function in women with breast cancer who did not use tamoxifen. DESIGN:Systematic review and meta-analysis. SETTING:University-based hospitals. PATIENT(S):Premenopausal women with breast cancer treated with chemotherap...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.fertnstert.2014.06.003

    authors: Vitek WS,Shayne M,Hoeger K,Han Y,Messing S,Fung C

    更新日期:2014-09-01 00:00:00

  • Endometriosis and infertility: a committee opinion.

    abstract::Women with endometriosis typically present with pelvic pain, infertility, or an adnexal mass, and may require surgery. Treatment of endometriosis in the setting of infertility raises a number of complex clinical questions that do not have simple answers. This document replaces the 2006 ASRM Practice Committee document...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2012.05.031

    authors: Practice Committee of the American Society for Reproductive Medicine.

    更新日期:2012-09-01 00:00:00

  • What factors currently limit magnetic resonance-guided focused ultrasound of leiomyomas? A survey conducted at the first international symposium devoted to clinical magnetic resonance-guided focused ultrasound.

    abstract:OBJECTIVE:To see if clinicians' impressions were influenced by expert opinion on patient selection criteria that influence magnetic resonance-guided focused ultrasound (MRgFUS) leiomyoma treatment. DESIGN:Survey-based study. SETTING:First international symposium devoted to MRgFUS, "MRgFUS 2008," October 6-7, 2008, Wa...

    journal_title:Fertility and sterility

    pub_type:

    doi:10.1016/j.fertnstert.2009.02.083

    authors: Taran FA,Hesley GK,Gorny KR,Stewart EA

    更新日期:2010-06-01 00:00:00

  • The dilemma of endometriosis: is consensus possible with an enigma?

    abstract::Many will agree that the use of laparoscopy to diagnose and potientially treat endometriosis in patients who suffer from infertility has been superseded by IVF and sometimes oocyte donation, especially in older patients. The findings of our study add another dimension to management of endometriosis in the setting of i...

    journal_title:Fertility and sterility

    pub_type: 评论,杂志文章,评审

    doi:10.1016/j.fertnstert.2005.06.033

    authors: Nezhat C,Littman ED,Lathi RB,Berker B,Westphal LM,Giudice LC,Milki AA

    更新日期:2005-12-01 00:00:00

  • Protein expression profiling of endometriosis: validation of 2-mm tissue microarrays.

    abstract::Tissue microarrays (TMAs) are useful tools for studying protein expression in endometriosis. Tissue microarray analyses of immunohistochemical profiles of estrogen receptor-alpha and P receptor corroborate previously published results from the use of conventional immunohistochemistry, thus validating TMA use in endome...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2004.06.044

    authors: Kamat AA,Younes PS,Sayeeduddin M,Wheeler TM,Simpson JL,Agoulnik AI

    更新日期:2004-12-01 00:00:00

  • The effect of gonadotropin-releasing hormone agonists on growth hormone secretion in adult premenopausal women.

    abstract::Suppression of the pituitary-gonadal axis by the administration of gonadotropin-releasing hormone agonists (GnRH-a) has been used for a variety of endocrinological and gynecological disorders. The suppressive effect of GnRH-a on luteinizing hormone, follicle-stimulating hormone, and sex steroid production is well docu...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)53639-5

    authors: Word RA,Odom MJ,Byrd W,Carr BR

    更新日期:1990-07-01 00:00:00

  • Growth factor expression by human oviduct and buffalo rat liver coculture cells.

    abstract:OBJECTIVE:To characterize growth factor gene expression by passaged coculture cell lines demonstrated to enhance in vitro pre-embryo growth. DESIGN:Ribonucleic acids isolated from the isthmus, ampullary, and fimbriae portions of the human oviduct, and from buffalo rat liver cell monolayers were subjected to Northern a...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(97)81382-9

    authors: Barmat LI,Worrilow KC,Paynton BV

    更新日期:1997-04-01 00:00:00

  • Functional differentiation in progesterone secretion by granulosa versus cumulus cells in the human preovulatory follicle and the effect of different induction of ovulation protocols.

    abstract:OBJECTIVE:To investigate P secretion by granulosa cells (GCs) versus cumulus cells derived from human preovulatory follicles. DESIGN:Cells were recovered by aspiration of preovulatory follicles in 44 women participating in an IVF program. Induction of ovulation was performed using clomiphene citrate, hMG and hCG (grou...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)56404-8

    authors: Dirnfeld M,Goldman S,Gonen Y,Koifman M,Lissak A,Kraiem Z,Abramovici H

    更新日期:1993-12-01 00:00:00

  • Uterine artery occlusion at myomectomy.

    abstract:OBJECTIVE:To demonstrate three approaches to uterine artery occlusion at time of myomectomy as a blood-sparing intraoperative technique. DESIGN:A step-by-step explanation of the procedure with surgical video footage. SETTING:Academic medical center. PATIENT(S):Patients undergoing laparoscopic myomectomy, for whom a ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2019.01.019

    authors: Zakhari A,Sanders AP,Murji A

    更新日期:2019-05-01 00:00:00

  • Two cases of cholestasis in the first trimester of pregnancy after ovarian hyperstimulation.

    abstract:OBJECTIVE:To report two cases of early onset cholestasis of pregnancy associated with IVF and ovarian hyperstimulation syndrome. DESIGN:Case report. SETTING:University-based IVF program. PATIENT(S):Two patients with first-trimester cholestasis of pregnancy after IVF that was associated with ovarian hyperstimulation ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.08.072

    authors: Zamah AM,El-Sayed YY,Milki AA

    更新日期:2008-10-01 00:00:00

  • Perinatal outcome of twin pregnancies after early transvaginal multifetal pregnancy reduction.

    abstract:OBJECTIVE:To compare the pregnancy outcomes of twin pregnancies following early transvaginal multifetal pregnancy reduction (MPR) with nonreduced twin gestations. DESIGN:Prospective cohort study. SETTING:Two tertiary medical centers. PATIENT(S):A cohort of 77 multiple pregnancies after reduction to twins and 78 dich...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.fertnstert.2014.01.032

    authors: Haas J,Hourvitz A,Dor J,Elizur S,Yinon Y,Barzilay E,Shulman A

    更新日期:2014-05-01 00:00:00

  • The cation composition of the seminal plasma and prostatic fluid and its correlation to semen quality.

    abstract::The concentrations of calcium, magnesium, and zinc were measured by atomic absorption spectrometry. The concentrations of all three cations were found to be strongly correlated with one another and with acidity (pH). Analysis of the relative concentrations in prostatic fluid, split ejaculates, and whole seminal plasma...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)43281-4

    authors: Homonnai ZT,Matzkin H,Fainman N,Paz G,Kraicer PF

    更新日期:1978-05-01 00:00:00

  • Reevaluating response and failure of medical treatment of endometriosis: a systematic review.

    abstract:OBJECTIVE:To assess patient response rates to medical therapies used to treat endometriosis-associated pain. DESIGN:A systematic review with the use of Medline and Embase. SETTING:Not applicable. PATIENT(S):Women receiving medical therapy to treat endometriosis. INTERVENTIONS(S):None. MAIN OUTCOME MEASURE(S):The p...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.fertnstert.2017.05.004

    authors: Becker CM,Gattrell WT,Gude K,Singh SS

    更新日期:2017-07-01 00:00:00

  • Human cumulus cell gene expression as a biomarker of pregnancy outcome after single embryo transfer.

    abstract:OBJECTIVE:To identify the cumulus cell gene expression associated with oocyte developmental competence, specifically live birth, after single ET (SET) assisted reproductive technology. DESIGN:Retrospective gene expression analysis in human cumulus cells from oocytes that established a pregnancy resulting in live birth...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.04.033

    authors: Gebhardt KM,Feil DK,Dunning KR,Lane M,Russell DL

    更新日期:2011-07-01 00:00:00

  • Higher luteinizing hormone levels associated with antimüllerian hormone in postmenarchal daughters of women with polycystic ovary syndrome.

    abstract:OBJECTIVE:To study the reproductive and metabolic differences between daughters of women with polycystic ovary syndrome (PCOSd) and control women (Cd) after menarche. DESIGN:Case-control study. SETTING:Clinical endocrinology unit. PATIENT(S):We studied 43 PCOSd and 28 Cd 1.5-6 years after menarche. INTERVENTION(S):...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2018.10.011

    authors: Crisosto N,Ladrón de Guevara A,Echiburú B,Maliqueo M,Cavada G,Codner E,Paez F,Sir-Petermann T

    更新日期:2019-02-01 00:00:00

  • Retroperitoneal mobilization of the vas deferens in the complex vasovasostomy.

    abstract::Anatomic distances along retroperitoneal, inguinal, and infrainguinal segments of the vas deferens were measured in 14 formalin fixed cadavers and in 15 recently postmortem males. There were no significant differences in segment lengths between the two groups nor between the right and left vasa. Data from the recent p...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)53959-4

    authors: Buch JP,Woods T

    更新日期:1990-11-01 00:00:00