Abstract：
:Macromolecular cell markers are essential for the classification and characterization of the highly complex and cellularly diverse vertebrate retina. Although a plethora of markers are described in the current literature, the immunoreactivity of these markers in normal human tissue has not been fully determined. This is problematic as they are quintessential to the characterization of morphological changes associated with human retinal disease. This review provides an overview of the macromolecular markers currently available to assess human retinal cell types. We draw on immunohistochemical studies conducted in our laboratories to describe marker immunoreactivity in human retina alongside comparative descriptions in non-human tissues. Considering the growing number of eye banks services offering healthy and diseased human retinal tissue, this review provides a point of reference for future human retina studies and highlights key species specific disease applications of some macromolecular markers.
journal_name
Exp Eye Resjournal_title
Experimental eye researchauthors
de Souza CF,Nivison-Smith L,Christie DL,Polkinghorne P,McGhee C,Kalloniatis M,Acosta MLdoi
10.1016/j.exer.2016.01.002subject
Has Abstractpub_date
2016-09-01 00:00:00pages
135-48eissn
0014-4835issn
1096-0007pii
S0014-4835(16)30002-1journal_volume
150pub_type
杂志文章,评审abstract：:Ciliary ganglionectomy inhibits the development of myopia in chicks (Schmid et al., 1999), but has no effect on the compensatory responses to spectacle lenses (Schmid and Wildsoet, 1996). This study was done to assess the potential influence of the other parasympathetic input to the choroid, the pterygopalatine gangli...
journal_title：Experimental eye research
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journal_title：Experimental eye research
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journal_title：Experimental eye research
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pub_type： 杂志文章
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journal_title：Experimental eye research
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journal_title：Experimental eye research
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更新日期：2006-06-01 00:00:00
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journal_title：Experimental eye research
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journal_title：Experimental eye research
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