Abstract：
:Diabetes mellitus is a disabling, chronic cardiovascular and medical disease with a tremendous health, social and economic burden in our ageing communities. It has a prevalence of 10% to 30% in people older than 65 years of age, and more than half of all subjects with diabetes in the United States are older than 60 years of age. The main impact of diabetes in older adults stems from its effect on function, both physical and cognitive, that finally impairs their quality of life, although the impact on survival is modest. Frailty has emerged during the past 2 decades as the most powerful predictor of disability and other adverse outcomes, including mortality, disability and institutionalization in older adults. In this article we explore the relationship between diabetes and frailty, and we recognize that they are intimately related chronic medical conditions that result in huge societal and personal health burdens.
journal_name
Can J Diabetesjournal_title
Canadian journal of diabetesauthors
Sinclair AJ,Rodriguez-Mañas Ldoi
10.1016/j.jcjd.2015.09.004subject
Has Abstractpub_date
2016-02-01 00:00:00pages
77-83issue
1eissn
1499-2671issn
2352-3840pii
S1499-2671(15)00632-2journal_volume
40pub_type
杂志文章,评审abstract：OBJECTIVES:We aimed to build a risk score model to screen out the patients at high-risk status so as to prevent or delay the conversion of prediabetes to diabetes. METHODS:The population were divided into 2 groups: 1 was an exploratory population, and the other was a validation population. All the data were extracted ...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2016.02.013
更新日期：2016-10-01 00:00:00
abstract：:Effective glycemic control reduces the risk for diabetes-related complications. However, the majority of patients with type 2 diabetes still do not achieve glycemic targets. Beyond metformin therapy, current practice guidelines for the management of type 2 diabetes recommend individualized treatment based on patient a...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2015.09.001
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVES:Our purpose was to disseminate and implement the Diabetes Canada (formerly the Canadian Diabetes Association) 2013 Clinical Practice Guidelines and evaluate the impact of the dissemination and implementation strategy on process outcomes (reach, adoption, implementation and maintenance). METHODS:Our patient-...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2018.08.189
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:It was uncertain whether an algorithm that involves increasing insulin dosages by 1 unit/day may cause more hypoglycemia with the longer-acting insulin glargine 300 units/mL (GLA-300). The objective of this study was to compare safety and efficacy of 2 titration algorithms, INSIGHT and EDITION, for GLA-300 in...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.jcjd.2017.06.007
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVES:To investigate the support needs of elderly patients with diabetes and to classify elderly patients with diabetes living alone on the basis of support needs. METHODS:Support needs were derived from a literature review of relevant journals and interviews of outpatients as well as expert nurses in the field o...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jcjd.2015.09.005
更新日期：2016-02-01 00:00:00
abstract：:If a disease state is highly prevalent and its consequences are severe, it may be appropriate to seek methods to identify it early to forestall its development and complications. Diabetes mellitus is a proven risk factor for the development of atherosclerosis, although its face and outcome are changing, as shown in co...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2019.08.009
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVES:There are currently no recommendations on following the ketogenic diet (KD) in the context of diabetes and, therefore, health-care professionals may not be comfortable in supporting this dietary regimen. In this qualitative study, we aim to understand the perspective of patients with diabetes when following ...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2020.06.016
更新日期：2020-06-27 00:00:00
abstract：OBJECTIVES:Emerging evidence suggests that the neutrophil-to-lymphocyte ratio (NLR) may be a useful marker of inflammation and aortic stiffness. Markers of inflammation and aortic stiffness are both indicators of cardiovascular events. We, therefore, investigated whether the NLR is associated with aortic stiffness in p...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2015.01.004
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVES:This study describes associations between depressive symptoms and indices of obesity in a community sample of adults with prediabetes. The strengths of these associations were compared to those observed in individuals with normal blood glucose levels. METHODS:Cross-sectional data came from the baseline asse...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2018.05.005
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVES:To determine the long-term effects of changing the amount or source of dietary carbohydrate on quality of life (QOL), symptoms and dietary satisfaction in people with type 2 diabetes. METHODS:Subjects with diabetes treated by diet alone (n=162) were randomly assigned to high-carbohydrate/high-glycemic-index...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jcjd.2016.08.223
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVES:Hypokalemia, a frequently cited complication of diabetic ketoacidosis (DKA) treatment, can have critical implications, including arrhythmias and death. We assessed the prevalence of hypokalemia and its associated factors in patients with DKA at our tertiary-care centre and identified opportunities to improve...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2015.10.002
更新日期：2016-06-01 00:00:00
abstract：:The Publisher regrets that this article is an accidental duplication of an article that has already been published, http://dx.doi.org/10.1016/j.jcjd.2017.02.003. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-busines...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2017.02.003
更新日期：2017-04-05 00:00:00
abstract：OBJECTIVES:Routine food insecurity screening is recommended in diabetes care to inform more tailored interventions that better support diabetes self-management among food-insecure patients. This pilot study explored the acceptability and feasibility of a food insecurity screening initiative within a diabetes care setti...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2017.06.004
更新日期：2018-06-01 00:00:00
abstract：:Epidemiological studies suggest that adults and children who are habitual short sleepers tend to have a higher body mass index, fat percentage and abdominal circumference when compared to average-duration sleepers. Reduced or disturbed sleep is also associated with certain predictors of type 2 diabetes, such as glucos...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2013.02.060
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVES:East African (EA) women are a subpopulation who are at very high risk for gestational diabetes (GDM) and poor obstetric outcomes, but little is known about the care experiences of this understudied group. The objective of this study was to document the impact of a diagnosis of GDM and the perceptions of diab...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2018.01.013
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:To examine the relationship of inadequate health literacy (HL) with changes in depressive symptoms, health-related quality of life and cardiometabolic outcomes in patients with type 2 diabetes mellitus recently screened positive for depression. METHODS:Secondary analysis of data from a clinical trial (N=154)...
journal_title：Canadian journal of diabetes
pub_type： 临床试验,杂志文章
doi：10.1016/j.jcjd.2014.11.005
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:This article describes a qualitative research study that examines the encounters by patients of low socioeconomic status with a group medical visit (GMV) program for individuals with or at risk for diabetes. The goal of this study was to generate insights that could be used to guide the development of an inne...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2014.03.012
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVES:(1) to describe pediatric patients with T1D and their caregivers' perceptions of measures of glycemic control (hemoglobin [A1C] and blood glucose [BG] levels) and (2) to determine the relationship between patients' and caregivers' perceptions of measures of glycemic control with actual A1C levels and adheren...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2017.07.002
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVE:As part of a larger project to develop quality standards in perioperative diabetes management, the goal of this project was to assess self-reported management of surgical patients with diabetes across healthcare institutions and specialties in Canada. METHODS:Current practice of perioperative management of p...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2020.10.011
更新日期：2020-10-27 00:00:00
abstract：:Current management options for treating type 2 diabetes are diverse. Many different classes of antidiabetes therapies are used in clinic, and several new candidates are in late-phase clinical trial. This therapeutic abundance is a windfall for patients because it facilitates individualized patient care. Evidence-based...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2017.08.242
更新日期：2017-10-01 00:00:00
abstract：:Glucagon-like peptide-1 receptor agonists and sodium-dependent glucose cotransporter-2 inhibitors have demonstrated clinically significant benefits on glycated hemoglobin, weight, blood pressure and cardiorenal outcomes. The emerging evidence from clinical trials and meta-analyses that assessed the combination of thes...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2020.09.005
更新日期：2020-09-14 00:00:00
abstract：OBJECTIVES:Individuals with type 1 diabetes try to manage the risk of exercise-induced hypoglycemia by either pre-exercise/pre-meal bolus insulin dose reductions and/or consuming additional carbohydrates during exercise. Both strategies have proven to be effective in offsetting hypoglycemia, but it remains unclear whic...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2020.03.003
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVES:People with type 2 diabetes and increased systolic blood pressure (SBP) are at high risk of cardiovascular disease (CVD). In this study, we aimed to investigate the association between CVD-related hospital payments and SBP and tested whether this association is influenced by diabetes peer support. METHODS:T...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2020.07.008
更新日期：2020-08-10 00:00:00
abstract：OBJECTIVES:The objective of the study was to describe the demographic and clinical characteristics of MedsCheck Diabetes (MCD) recipients in Ontario between program launch on September 1, 2010, and March 31, 2014. METHODS:This cohort study leveraged linked administrative claims data. Trends in MCD claims and recipient...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2016.12.001
更新日期：2017-06-01 00:00:00
abstract：:Routine quantification of urinary albumin levels is recommended for all Canadians with diabetes, yet many controversies remain when interpreting these tests. Elevated levels of albuminuria have traditionally been labeled as either microalbuminuria, representing 30 to 300 mg of albuminuria per day (a range not reliably...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2014.07.221
更新日期：2014-10-01 00:00:00
abstract：:Diabetes mellitus is one of the most common chronic diseases worldwide and a leading cause of morbidity and mortality. A high prevalence of type 2 diabetes mellitus has been noted among the South Asian population, in general, and migrant South Asians. Self-management is considered a proponent to the management of diab...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2019.04.010
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVES:Postpartum mothers with gestational diabetes may remain with either type 2 diabetes mellitus, impaired glucose tolerance or impaired fasting glucose. Our aim in this study was to identify maternal variables that could predict 1 or more of these conditions. METHODS:In 193 singleton pregnancies with gestation...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2020.06.008
更新日期：2020-06-17 00:00:00
abstract：:Brain-derived neurotrophic factor (BDNF), a member of neurotrophin growth factor family, physiologically mediates induction of neurogenesis and neuronal differentiation, promotes neuronal growth and survival and maintains synaptic plasticity and neuronal interconnections. Unlike the central nervous system, its secreti...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2016.08.228
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVES:This study aimed to describe the risk of developing diabetes and the probable prevalence of diabetes and prediabetes in residents of subsidized or social housing who were 55 years of age or older. METHODS:We conducted a cross-sectional study using data collected from an ongoing community health program in s...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2020.10.005
更新日期：2020-10-16 00:00:00
abstract：OBJECTIVES:Examining the diets of people living with type 2 diabetes may improve understanding of how diet affects disease progression. We derived dietary patterns in adults living with type 2 diabetes and explored associations among patterns, sociodemographic variables and cardiometabolic risk factors. METHODS:Dietar...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2015.11.006
更新日期：2016-08-01 00:00:00
