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Basal Glucose on Tolerance Test During Pregnancy Predicts Impaired Fasting Glucose and Type 2 Diabetes Within 2 Months After Gestational Diabetes.

Abstract：

OBJECTIVES:Postpartum mothers with gestational diabetes may remain with either type 2 diabetes mellitus, impaired glucose tolerance or impaired fasting glucose. Our aim in this study was to identify maternal variables that could predict 1 or more of these conditions. METHODS:In 193 singleton pregnancies with gestational diabetes, we applied bivariate logistic regression and receiver-operating characteristic curves to data from the index glucose-challenge test that allowed the diagnosis of gestational diabetes. RESULTS:Receiver-operating characteristic curves of fasting glucose from the index glucose-challenge test predicted impaired fasting glucose and type 2 diabetes mellitus combined, with a sensitivity of 100%, false-positive rate of 40.5%, area under the curve of 0.849, p=0.004 and positive predictive value 45%, and with a cutoff point of 4.7 mmol/L. CONCLUSIONS:At the time of diagnosis of gestational diabetes during pregnancy, a basal glucose level of ≥4.7 mmol/L on index glucose-challenge test indicates a 45% probability of either type 2 diabetes mellitus or impending diabetes early postpartum.

journal_name

Can J Diabetes

journal_title

Canadian journal of diabetes

authors

Olmos P,Borzone G,Poblete A

doi

10.1016/j.jcjd.2020.06.008

subject

Has Abstract

pub_date

2020-06-17 00:00:00

eissn

1499-2671

issn

2352-3840

pii

S1499-2671(20)30181-7

pub_type

杂志文章

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