Abstract:
OBJECTIVES:New-onsetdiabetes after transplant (NODAT) is a major contributor to cardiovascular disease after transplantation. Kidney transplantation (KT) recipients have low levels of exercise capacity. Resistance training (RT) might be of special benefit in this population because underlying disease and immunosuppressive drugs favour muscle loss and insulin resistance. The aim of this study was to assess the feasibility of implementing an RT program within a population of KT recipients and its impact on the incidence of NODAT and cardiometabolic risk factors. METHODS:This pilot study was an open-randomized study. We randomized 24 patients with a 1:1 allocation to 2 parallel groups, the exercise group (E) or the control group (C). The E group was submitted to RT 3 times a week for 16 weeks. Anthropometric, body composition, cardiometabolic risk factors, muscle strength, cardiorespiratory fitness and well-being were measured before and after 16 weeks. RESULTS:Of the 24 recruited participants, 20 completed the study (10 in the E group and 10 in the C group). No injuries were reported. The intervention was associated with a significant increase in muscle strength (p=0.003). A significant group effect, in favour of the E group, was detected for the well-being score (p=0.03). However, no changes in body composition, cardiometabolic risk factors or cardiorespiratory fitness were noted for either group after the intervention. CONCLUSIONS:This pilot study suggests that RT appears to be secure and feasible and improves strength and well-being in patients after KT. However, it does not improve cardiometabolic risk factors.
journal_name
Can J Diabetesjournal_title
Canadian journal of diabetesauthors
Karelis AD,Hébert MJ,Rabasa-Lhoret R,Räkel Adoi
10.1016/j.jcjd.2015.08.014subject
Has Abstractpub_date
2016-10-01 00:00:00pages
382-388issue
5eissn
1499-2671issn
2352-3840pii
S1499-2671(15)00570-5journal_volume
40pub_type
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journal_title:Canadian journal of diabetes
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journal_title:Canadian journal of diabetes
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更新日期:2013-06-01 00:00:00
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pub_type: 杂志文章
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journal_title:Canadian journal of diabetes
pub_type: 杂志文章
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更新日期:2016-10-01 00:00:00
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journal_title:Canadian journal of diabetes
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更新日期:2014-06-01 00:00:00
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journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
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journal_title:Canadian journal of diabetes
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journal_title:Canadian journal of diabetes
pub_type: 杂志文章
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journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
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更新日期:2014-04-01 00:00:00
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更新日期:2016-02-01 00:00:00
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pub_type: 杂志文章,meta分析
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更新日期:2018-10-01 00:00:00
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journal_title:Canadian journal of diabetes
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
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journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2017.03.003
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journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2016.07.005
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journal_title:Canadian journal of diabetes
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更新日期:2015-08-01 00:00:00
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更新日期:2018-06-01 00:00:00
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更新日期:2009-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-12-01 00:00:00
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pub_type: 历史文章,杂志文章,评审
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更新日期:2016-08-01 00:00:00
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pub_type: 杂志文章,撤回出版物
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更新日期:2020-09-14 00:00:00
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更新日期:2013-08-01 00:00:00
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更新日期:2018-06-01 00:00:00