Abstract:
:Hyperglycemia is a significant cause of morbidity and mortality, often resulting in adverse outcomes. This review aimed to identify predictors of adverse outcomes, such as repeated hospital visits, hospitalization or death, in patients presenting to the emergency department (ED) with hyperglycemia. Electronic searches of Medline and EMBASE were conducted for studies in English of patients presenting to the ED with hyperglycemia. Both adult and pediatric populations were included, with and without diabetes. Two reviewers independently screened all titles and abstracts for relevance. If consensus was not reached, full-length manuscripts were reviewed. For discrepancies, a third reviewer was consulted. Study quality was assessed using the Newcastle-Ottawa Quality Assessment Scale. Study- and patient-specific data were extracted and presented descriptively. Eight observational studies were reviewed; they included a total of 96,970 patients. Predictors of adverse outcomes included age, lowest income quintile, urban dwellers, presence of comorbidities, coexisting hyperlactatemia, having a family physician, elevated serum creatinine level, diabetes managed with insulin, sentinel visit for hyperglycemia in the past month, and high blood glucose level measured in the ED. Conflicting evidence was found for whether known history of diabetes was associated with risk. Factors associated with favourable outcomes included systolic blood pressure of 90 to 150 mmHg and tachycardia. This systematic review found 12 factors associated with adverse outcomes, and 2 factors associated with more favourable outcomes in patients presenting to the ED with hyperglycemia. These factors should be considered for easier identification of patients at higher risk for adverse outcomes to guide management and follow up.
journal_name
Can J Diabetesjournal_title
Canadian journal of diabetesauthors
Siddiqi L,VanAarsen K,Iansavichene A,Yan Jdoi
10.1016/j.jcjd.2018.11.008subject
Has Abstractpub_date
2019-07-01 00:00:00pages
361-369.e2issue
5eissn
1499-2671issn
2352-3840pii
S1499-2671(18)30408-8journal_volume
43pub_type
杂志文章abstract::The Publisher regrets that this article is an accidental duplication of an article that has already been published, http://dx.doi.org/10.1016/j.jcjd.2017.02.003. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-busines...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2017.02.003
更新日期:2017-04-05 00:00:00
abstract::Effective glycemic control reduces the risk for diabetes-related complications. However, the majority of patients with type 2 diabetes still do not achieve glycemic targets. Beyond metformin therapy, current practice guidelines for the management of type 2 diabetes recommend individualized treatment based on patient a...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2015.09.001
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVES:Our purpose was to disseminate and implement the Diabetes Canada (formerly the Canadian Diabetes Association) 2013 Clinical Practice Guidelines and evaluate the impact of the dissemination and implementation strategy on process outcomes (reach, adoption, implementation and maintenance). METHODS:Our patient-...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2018.08.189
更新日期:2019-06-01 00:00:00
abstract::Diabetic mastopathy is an uncommon, benign breast condition seen in type 1 and less frequently type 2 diabetic patients. It is characterized by a dense fibrous stromal proliferation of breast tissue, clinically mimicking cancerous masses, thus leading to worrisome investigations. Clinicians and pathologists must disti...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2013.12.008
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVES:The objective of the study was to describe the demographic and clinical characteristics of MedsCheck Diabetes (MCD) recipients in Ontario between program launch on September 1, 2010, and March 31, 2014. METHODS:This cohort study leveraged linked administrative claims data. Trends in MCD claims and recipient...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2016.12.001
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:We evaluated the prevalence of type 2 diabetes, obesity and metabolic syndrome according to International Diabetes Federation criteria in the First Nations Cree community of Mistissini, Quebec. METHODS:A cross-sectional study of 172 adults was performed as part of a broader regional environmental study. RES...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/S1499-2671(09)33006-3
更新日期:2009-01-01 00:00:00
abstract::Patients with diabetes who are in emerging adulthood, defined as the life stage between 18 and 29 years of age, have unique challenges in managing their illness and are at risk for acute complications and loss to follow up. This study's objective was to describe emergency department (ED) utilization because of hypergl...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2017.06.016
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:To determine the long-term effects of changing the amount or source of dietary carbohydrate on quality of life (QOL), symptoms and dietary satisfaction in people with type 2 diabetes. METHODS:Subjects with diabetes treated by diet alone (n=162) were randomly assigned to high-carbohydrate/high-glycemic-index...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jcjd.2016.08.223
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:Hypokalemia, a frequently cited complication of diabetic ketoacidosis (DKA) treatment, can have critical implications, including arrhythmias and death. We assessed the prevalence of hypokalemia and its associated factors in patients with DKA at our tertiary-care centre and identified opportunities to improve...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2015.10.002
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:The effects of hyperglycemia and normoglycemia on gallbladder emptying have not been studied in detail. This prospective case-control study was designed to investigate the gallbladder ejection fraction in patients with newly detected diabetes and to assess the impact of restoring normoglycemia on gallbladder ...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2014.07.223
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVES:The short version of the Activities-Specific Balance Confidence Scale (ABC-6) is advantageous in busy clinical or research settings because it can be administered in less time than the original 16-item Activities-Specific Balance Confidence Scale (ABC-16). This pilot study examined the convergent, discrimina...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2016.10.007
更新日期:2017-06-01 00:00:00
abstract::Diabetes mellitus is a disabling, chronic cardiovascular and medical disease with a tremendous health, social and economic burden in our ageing communities. It has a prevalence of 10% to 30% in people older than 65 years of age, and more than half of all subjects with diabetes in the United States are older than 60 ye...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2015.09.004
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:As part of a larger project to develop quality standards in perioperative diabetes management, the goal of this project was to assess self-reported management of surgical patients with diabetes across healthcare institutions and specialties in Canada. METHODS:Current practice of perioperative management of p...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2020.10.011
更新日期:2020-10-27 00:00:00
abstract::If a disease state is highly prevalent and its consequences are severe, it may be appropriate to seek methods to identify it early to forestall its development and complications. Diabetes mellitus is a proven risk factor for the development of atherosclerosis, although its face and outcome are changing, as shown in co...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2019.08.009
更新日期:2020-02-01 00:00:00
abstract::While dysglycemia (hyperglycemia, hypoglycemia and glucose variability) is clearly associated with increased mortality in critically ill patients, target range of blood glucose control remains controversial. Standardized insulin infusion protocols constitute the basis of treatment of these patients. The choice of prot...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2014.01.016
更新日期:2014-04-01 00:00:00
abstract::The prevalence of chronic metabolic diseases, such as diabetes, cardiovascular diseases and cancer, is increasing around the world. Nutritional interventions can reduce the prevalence and provide effective treatment, even when weight loss is not dramatic. The 2013 Canadian Diabetes Association Clinical Practice Guidel...
journal_title:Canadian journal of diabetes
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.jcjd.2016.05.005
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:This study aimed to describe the risk of developing diabetes and the probable prevalence of diabetes and prediabetes in residents of subsidized or social housing who were 55 years of age or older. METHODS:We conducted a cross-sectional study using data collected from an ongoing community health program in s...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2020.10.005
更新日期:2020-10-16 00:00:00
abstract:OBJECTIVE:The Goal Oriented controL of Diabetes in the Elderly populatioN (GOLDEN) Program assessed the management of older persons with type 2 diabetes in Canadian primary care. METHODS:Data were extracted from the records of 833 consecutively identified persons 65 years of age or older who had type 2 diabetes and we...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2017.03.003
更新日期:2018-02-01 00:00:00
abstract::Dietary modifications play a central role in the treatment of diabetes. Educating and empowering individuals to make better dietary choices is a challenging task. In this context, 1 potential dietetic approach to achieve better glycemic control in type 2 diabetes is often overlooked: the use of short-term dietary oatm...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2019.08.020
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:It was uncertain whether an algorithm that involves increasing insulin dosages by 1 unit/day may cause more hypoglycemia with the longer-acting insulin glargine 300 units/mL (GLA-300). The objective of this study was to compare safety and efficacy of 2 titration algorithms, INSIGHT and EDITION, for GLA-300 in...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jcjd.2017.06.007
更新日期:2017-10-01 00:00:00
abstract::Cerebral edema (CE) is a rare but potentially fatal complication of diabetic ketoacidosis (DKA) in children with type 1 diabetes. CE is frequently mentioned as being more common in young children. The primary objective of this study was to review the evidence suggesting that younger age is a risk factor for the develo...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2019.04.013
更新日期:2020-02-01 00:00:00
abstract::Diabetes mellitus is one of the most common chronic diseases worldwide and a leading cause of morbidity and mortality. A high prevalence of type 2 diabetes mellitus has been noted among the South Asian population, in general, and migrant South Asians. Self-management is considered a proponent to the management of diab...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2019.04.010
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:No research to date has compared the beliefs of adolescents, parents and physicians with respect to type 1 diabetes mellitus self-care perceptions and barriers. This study examined how adolescents with type 1 diabetes, their parents and physicians perceive 4 key diabetes self-care behaviours (testing blood gl...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2013.02.057
更新日期:2013-06-01 00:00:00
abstract::The importance of glycemic control in hospitalized patients has been a relatively recent revelation. There is somewhat contradictory evidence concerning the optimal glycemic target in critically ill patients. There is only indirect evidence in non-critically ill patients. This article reviews the evidence for glycemic...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2014.01.001
更新日期:2014-04-01 00:00:00
abstract::Glucagon-like peptide-1 receptor agonists and sodium-dependent glucose cotransporter-2 inhibitors have demonstrated clinically significant benefits on glycated hemoglobin, weight, blood pressure and cardiorenal outcomes. The emerging evidence from clinical trials and meta-analyses that assessed the combination of thes...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2020.09.005
更新日期:2020-09-14 00:00:00
abstract::We report the case of a patient with diabetes presenting a severe insulin-resistance syndrome due to the production of insulin autoantibodies by a lymphocytic lymphoma. We describe the various mechanisms leading to the production of insulin autoantibodies and insulin receptor autoantibodies and review the therapeutic ...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2016.02.007
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:We aimed to build a risk score model to screen out the patients at high-risk status so as to prevent or delay the conversion of prediabetes to diabetes. METHODS:The population were divided into 2 groups: 1 was an exploratory population, and the other was a validation population. All the data were extracted ...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2016.02.013
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To describe the use patterns of metformin-based antidiabetic regimens in patients with type 2 diabetes and to identify predictors of initiating metformin monotherapy. METHODS:By using administrative databases from Alberta, Canada, we identified all metformin users ages 65 years and older between 1998 and 201...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2013.04.008
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:With the expanding armamentarium of noninsulin therapies for type 2 diabetes mellitus, the use of insulin with various oral agents is becoming more common. In this study, we assessed the efficacy and cardiovascular (CV) safety of the dipeptidyl peptidase-4 inhibitor linagliptin as add-on to insulin in patient...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jcjd.2015.06.010
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:To investigate the support needs of elderly patients with diabetes and to classify elderly patients with diabetes living alone on the basis of support needs. METHODS:Support needs were derived from a literature review of relevant journals and interviews of outpatients as well as expert nurses in the field o...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jcjd.2015.09.005
更新日期:2016-02-01 00:00:00