Abstract：
:The importance of glycemic control in hospitalized patients has been a relatively recent revelation. There is somewhat contradictory evidence concerning the optimal glycemic target in critically ill patients. There is only indirect evidence in non-critically ill patients. This article reviews the evidence for glycemic targets in hospitalized patients. It also investigates which hospital-based treatments can act as barriers to attaining optimal blood glucose levels in hospital and system barriers to attaining those optimal levels. The systematic approach to and evaluation of in-hospital diabetes management has a short history. The first large clinical trial, the DIGAMI trial of peri-myocardial infarction insulin therapy, was published in 1995 (1). The first guideline discussion of in-hospital diabetes management occurred briefly in 2003, more fully in 2008 and 2013 (2-4) by the Canadian Diabetes Association; in 2005 and annually since then by the American Diabetes Association (5,6). Recently, there have been many more publications on the topic. A recent PubMed search, limited to the last 5 years, "hospital" and "diabetes" as a Medical Subject Headings (MeSH) major topic, revealed more than 5000 English-language clinical trials (PubMed.gov; accessed 6 Oct 2013). Still, relatively little is certain about appropriate glycemic targets in hospital. This has left us, in 2014, with consensus recommendations only for glycemic targets in non-critically ill patients from both the Canadian Diabetes Association Clinical Practice Guidelines (4) and the American Diabetes Association Standards of Medical Care in Diabetes (6). This article reviews recommended glycemic targets in various in-hospital populations and the barriers to obtaining them.
journal_name
Can J Diabetesjournal_title
Canadian journal of diabetesauthors
Miller DBdoi
10.1016/j.jcjd.2014.01.001subject
Has Abstractpub_date
2014-04-01 00:00:00pages
74-8issue
2eissn
1499-2671issn
2352-3840pii
S1499-2671(14)00002-1journal_volume
38pub_type
杂志文章,评审abstract：:Hyperglycemia is a significant cause of morbidity and mortality, often resulting in adverse outcomes. This review aimed to identify predictors of adverse outcomes, such as repeated hospital visits, hospitalization or death, in patients presenting to the emergency department (ED) with hyperglycemia. Electronic searches...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2018.11.008
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:With the expanding armamentarium of noninsulin therapies for type 2 diabetes mellitus, the use of insulin with various oral agents is becoming more common. In this study, we assessed the efficacy and cardiovascular (CV) safety of the dipeptidyl peptidase-4 inhibitor linagliptin as add-on to insulin in patient...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jcjd.2015.06.010
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVE:To describe the use patterns of metformin-based antidiabetic regimens in patients with type 2 diabetes and to identify predictors of initiating metformin monotherapy. METHODS:By using administrative databases from Alberta, Canada, we identified all metformin users ages 65 years and older between 1998 and 201...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2013.04.008
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVES:This study describes associations between depressive symptoms and indices of obesity in a community sample of adults with prediabetes. The strengths of these associations were compared to those observed in individuals with normal blood glucose levels. METHODS:Cross-sectional data came from the baseline asse...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2018.05.005
更新日期：2018-12-01 00:00:00
abstract：:If a disease state is highly prevalent and its consequences are severe, it may be appropriate to seek methods to identify it early to forestall its development and complications. Diabetes mellitus is a proven risk factor for the development of atherosclerosis, although its face and outcome are changing, as shown in co...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2019.08.009
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVES:The short version of the Activities-Specific Balance Confidence Scale (ABC-6) is advantageous in busy clinical or research settings because it can be administered in less time than the original 16-item Activities-Specific Balance Confidence Scale (ABC-16). This pilot study examined the convergent, discrimina...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2016.10.007
更新日期：2017-06-01 00:00:00
abstract：:Routine quantification of urinary albumin levels is recommended for all Canadians with diabetes, yet many controversies remain when interpreting these tests. Elevated levels of albuminuria have traditionally been labeled as either microalbuminuria, representing 30 to 300 mg of albuminuria per day (a range not reliably...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2014.07.221
更新日期：2014-10-01 00:00:00
abstract：:Current management options for treating type 2 diabetes are diverse. Many different classes of antidiabetes therapies are used in clinic, and several new candidates are in late-phase clinical trial. This therapeutic abundance is a windfall for patients because it facilitates individualized patient care. Evidence-based...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2017.08.242
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVES:South Asian immigrants are generally healthy upon arrival, but precipitously develop diabetes after immigration. Whether cultural and psychosocial factors contribute to diabetes risk in this ethnic minority group remains unclear. Existing prediction models focus primarily on clinical and lifestyle factors. T...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2019.04.015
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVES:We aimed to build a risk score model to screen out the patients at high-risk status so as to prevent or delay the conversion of prediabetes to diabetes. METHODS:The population were divided into 2 groups: 1 was an exploratory population, and the other was a validation population. All the data were extracted ...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2016.02.013
更新日期：2016-10-01 00:00:00
abstract：:Diabetes mellitus is one of the most common chronic diseases worldwide and a leading cause of morbidity and mortality. A high prevalence of type 2 diabetes mellitus has been noted among the South Asian population, in general, and migrant South Asians. Self-management is considered a proponent to the management of diab...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2019.04.010
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:The Goal Oriented controL of Diabetes in the Elderly populatioN (GOLDEN) Program assessed the management of older persons with type 2 diabetes in Canadian primary care. METHODS:Data were extracted from the records of 833 consecutively identified persons 65 years of age or older who had type 2 diabetes and we...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2017.03.003
更新日期：2018-02-01 00:00:00
abstract：:Epidemiological studies suggest that adults and children who are habitual short sleepers tend to have a higher body mass index, fat percentage and abdominal circumference when compared to average-duration sleepers. Reduced or disturbed sleep is also associated with certain predictors of type 2 diabetes, such as glucos...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2013.02.060
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVES:Routine food insecurity screening is recommended in diabetes care to inform more tailored interventions that better support diabetes self-management among food-insecure patients. This pilot study explored the acceptability and feasibility of a food insecurity screening initiative within a diabetes care setti...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2017.06.004
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVES:Emerging evidence suggests that the neutrophil-to-lymphocyte ratio (NLR) may be a useful marker of inflammation and aortic stiffness. Markers of inflammation and aortic stiffness are both indicators of cardiovascular events. We, therefore, investigated whether the NLR is associated with aortic stiffness in p...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2015.01.004
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:The self-monitoring of blood glucose plays a critical role in management of diabetes mellitus. Although laboratory comparisons of glucose meter accuracy are often acceptable, clinical comparisons show frequent inaccuracies. In this paper, we evaluate the accuracy of self-monitoring blood glucose meters using ...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,撤回出版物
doi：10.1016/j.jcjd.2016.04.004
更新日期：2016-05-01 00:00:00
abstract：:Dietary modifications play a central role in the treatment of diabetes. Educating and empowering individuals to make better dietary choices is a challenging task. In this context, 1 potential dietetic approach to achieve better glycemic control in type 2 diabetes is often overlooked: the use of short-term dietary oatm...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2019.08.020
更新日期：2020-06-01 00:00:00
abstract：:Low grade inflammation has been linked to risk of type 2 diabetes and atherosclerotic vascular diseases. Obesity and, in particular, abdominal obesity increase the risk of diabetes and atherosclerotic vascular diseases. One of the mechanisms could be low grade inflammation and vascular endothelial dysfunction. Permane...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2013.07.029
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to determine whether perinatal outcomes differ between Caucasian and Asian subgroups of women with gestational diabetes mellitus (GDM) through use of standard vs ethnicity-specific birthweight curves. METHODS:This retrospective cohort study included 537 women with GDM, within the et...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2019.06.006
更新日期：2019-12-01 00:00:00
abstract：:Cerebral edema (CE) is a rare but potentially fatal complication of diabetic ketoacidosis (DKA) in children with type 1 diabetes. CE is frequently mentioned as being more common in young children. The primary objective of this study was to review the evidence suggesting that younger age is a risk factor for the develo...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2019.04.013
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVES:To describe trends in blood glucose test strip (TS) utilization and cost in Saskatchewan. METHODS:A retrospective analysis of TS use between January 1, 1996, and December 31, 2013, was conducted using population-based health administrative databases in Saskatchewan. The prescription drug database was used t...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2017.01.004
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVES:To investigate the content, quality and popularity of information about type 2 diabetes available on YouTube. METHODS:We searched YouTube with the terms Diabetes, Diabetes type 2, Diabetes South Asians, Diabetes Punjabi and Diabetes Hindi to identify videos concerning type 2 diabetes. A team of health-care ...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2017.10.056
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:No research to date has compared the beliefs of adolescents, parents and physicians with respect to type 1 diabetes mellitus self-care perceptions and barriers. This study examined how adolescents with type 1 diabetes, their parents and physicians perceive 4 key diabetes self-care behaviours (testing blood gl...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2013.02.057
更新日期：2013-06-01 00:00:00
abstract：:Diabetic mastopathy is an uncommon, benign breast condition seen in type 1 and less frequently type 2 diabetic patients. It is characterized by a dense fibrous stromal proliferation of breast tissue, clinically mimicking cancerous masses, thus leading to worrisome investigations. Clinicians and pathologists must disti...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2013.12.008
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVES:To examine the association between meeting physical-activity recommendations and health-related quality of life (HRQL) in adults with type 2 diabetes. METHODS:Data from the Alberta's Caring for Diabetes cohort were used. Self-report questionnaires were mailed to patients with type 2 diabetes who were living...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2016.07.004
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVES:Examining the diets of people living with type 2 diabetes may improve understanding of how diet affects disease progression. We derived dietary patterns in adults living with type 2 diabetes and explored associations among patterns, sociodemographic variables and cardiometabolic risk factors. METHODS:Dietar...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2015.11.006
更新日期：2016-08-01 00:00:00
abstract：OBJECTIVE:The effects of hyperglycemia and normoglycemia on gallbladder emptying have not been studied in detail. This prospective case-control study was designed to investigate the gallbladder ejection fraction in patients with newly detected diabetes and to assess the impact of restoring normoglycemia on gallbladder ...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2014.07.223
更新日期：2015-04-01 00:00:00
abstract：:Brain-derived neurotrophic factor (BDNF), a member of neurotrophin growth factor family, physiologically mediates induction of neurogenesis and neuronal differentiation, promotes neuronal growth and survival and maintains synaptic plasticity and neuronal interconnections. Unlike the central nervous system, its secreti...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.jcjd.2016.08.228
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVES:People with type 2 diabetes and increased systolic blood pressure (SBP) are at high risk of cardiovascular disease (CVD). In this study, we aimed to investigate the association between CVD-related hospital payments and SBP and tested whether this association is influenced by diabetes peer support. METHODS:T...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2020.07.008
更新日期：2020-08-10 00:00:00
abstract：OBJECTIVES:The objective of the study was to describe the demographic and clinical characteristics of MedsCheck Diabetes (MCD) recipients in Ontario between program launch on September 1, 2010, and March 31, 2014. METHODS:This cohort study leveraged linked administrative claims data. Trends in MCD claims and recipient...
journal_title：Canadian journal of diabetes
pub_type： 杂志文章
doi：10.1016/j.jcjd.2016.12.001
更新日期：2017-06-01 00:00:00
