Abstract:
OBJECTIVE:The effects of hyperglycemia and normoglycemia on gallbladder emptying have not been studied in detail. This prospective case-control study was designed to investigate the gallbladder ejection fraction in patients with newly detected diabetes and to assess the impact of restoring normoglycemia on gallbladder ejection fraction in such patients. METHODS:(99m)Tc-mebrofenin scintigraphy was performed in 22 patients with newly detected type 2 diabetes for measurement of gallbladder ejection fraction. The scintigraphy was performed at the time of first presentation and again 6 months after control of diabetes (glycated hemoglobin [A1C] <7%). Also, gallbladder ejection fraction was measured in 20 age- and sex-matched controls without diabetes. RESULTS:Gallbladder ejection fraction was lower in patients with newly detected diabetes compared with controls (31.4%±5.9% vs. 70.7%±4.3%, p<0.001). Gallbladder ejection fraction did not improve after the treatment of diabetes mellitus (21.3%±5.7%, p=0.395). CONCLUSIONS:Gallbladder ejection fraction was markedly reduced in patients with newly detected diabetes compared to controls without diabetes. Control of diabetes and normalization of A1C did not reverse the motility defect.
journal_name
Can J Diabetesjournal_title
Canadian journal of diabetesauthors
Arshad F,Laway BA,Rather TA,Kuchay MS,Khan SHdoi
10.1016/j.jcjd.2014.07.223subject
Has Abstractpub_date
2015-04-01 00:00:00pages
101-4issue
2eissn
1499-2671issn
2352-3840pii
S1499-2671(14)00529-2journal_volume
39pub_type
杂志文章abstract:OBJECTIVES:Hypokalemia, a frequently cited complication of diabetic ketoacidosis (DKA) treatment, can have critical implications, including arrhythmias and death. We assessed the prevalence of hypokalemia and its associated factors in patients with DKA at our tertiary-care centre and identified opportunities to improve...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2015.10.002
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:We aimed to build a risk score model to screen out the patients at high-risk status so as to prevent or delay the conversion of prediabetes to diabetes. METHODS:The population were divided into 2 groups: 1 was an exploratory population, and the other was a validation population. All the data were extracted ...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2016.02.013
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:To investigate the support needs of elderly patients with diabetes and to classify elderly patients with diabetes living alone on the basis of support needs. METHODS:Support needs were derived from a literature review of relevant journals and interviews of outpatients as well as expert nurses in the field o...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jcjd.2015.09.005
更新日期:2016-02-01 00:00:00
abstract::Diabetic mastopathy is an uncommon, benign breast condition seen in type 1 and less frequently type 2 diabetic patients. It is characterized by a dense fibrous stromal proliferation of breast tissue, clinically mimicking cancerous masses, thus leading to worrisome investigations. Clinicians and pathologists must disti...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2013.12.008
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVES:Examining the diets of people living with type 2 diabetes may improve understanding of how diet affects disease progression. We derived dietary patterns in adults living with type 2 diabetes and explored associations among patterns, sociodemographic variables and cardiometabolic risk factors. METHODS:Dietar...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2015.11.006
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:To investigate the content, quality and popularity of information about type 2 diabetes available on YouTube. METHODS:We searched YouTube with the terms Diabetes, Diabetes type 2, Diabetes South Asians, Diabetes Punjabi and Diabetes Hindi to identify videos concerning type 2 diabetes. A team of health-care ...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2017.10.056
更新日期:2018-08-01 00:00:00
abstract::While dysglycemia (hyperglycemia, hypoglycemia and glucose variability) is clearly associated with increased mortality in critically ill patients, target range of blood glucose control remains controversial. Standardized insulin infusion protocols constitute the basis of treatment of these patients. The choice of prot...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2014.01.016
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:To describe trends in blood glucose test strip (TS) utilization and cost in Saskatchewan. METHODS:A retrospective analysis of TS use between January 1, 1996, and December 31, 2013, was conducted using population-based health administrative databases in Saskatchewan. The prescription drug database was used t...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2017.01.004
更新日期:2018-02-01 00:00:00
abstract::Glucagon-like peptide-1 receptor agonists and sodium-dependent glucose cotransporter-2 inhibitors have demonstrated clinically significant benefits on glycated hemoglobin, weight, blood pressure and cardiorenal outcomes. The emerging evidence from clinical trials and meta-analyses that assessed the combination of thes...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2020.09.005
更新日期:2020-09-14 00:00:00
abstract:OBJECTIVES:To examine the association between meeting physical-activity recommendations and health-related quality of life (HRQL) in adults with type 2 diabetes. METHODS:Data from the Alberta's Caring for Diabetes cohort were used. Self-report questionnaires were mailed to patients with type 2 diabetes who were living...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2016.07.004
更新日期:2017-02-01 00:00:00
abstract::The importance of glycemic control in hospitalized patients has been a relatively recent revelation. There is somewhat contradictory evidence concerning the optimal glycemic target in critically ill patients. There is only indirect evidence in non-critically ill patients. This article reviews the evidence for glycemic...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2014.01.001
更新日期:2014-04-01 00:00:00
abstract::Hyperglycemia is a significant cause of morbidity and mortality, often resulting in adverse outcomes. This review aimed to identify predictors of adverse outcomes, such as repeated hospital visits, hospitalization or death, in patients presenting to the emergency department (ED) with hyperglycemia. Electronic searches...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2018.11.008
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:This article describes a qualitative research study that examines the encounters by patients of low socioeconomic status with a group medical visit (GMV) program for individuals with or at risk for diabetes. The goal of this study was to generate insights that could be used to guide the development of an inne...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2014.03.012
更新日期:2014-06-01 00:00:00
abstract::Diabetes mellitus is a disabling, chronic cardiovascular and medical disease with a tremendous health, social and economic burden in our ageing communities. It has a prevalence of 10% to 30% in people older than 65 years of age, and more than half of all subjects with diabetes in the United States are older than 60 ye...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2015.09.004
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine whether perinatal outcomes differ between Caucasian and Asian subgroups of women with gestational diabetes mellitus (GDM) through use of standard vs ethnicity-specific birthweight curves. METHODS:This retrospective cohort study included 537 women with GDM, within the et...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2019.06.006
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:The short version of the Activities-Specific Balance Confidence Scale (ABC-6) is advantageous in busy clinical or research settings because it can be administered in less time than the original 16-item Activities-Specific Balance Confidence Scale (ABC-16). This pilot study examined the convergent, discrimina...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2016.10.007
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:Although metformin has traditionally been avoided in pregnancy, evidence now supports its safety and efficacy for management of gestational diabetes mellitus (GDM). The primary objective of this study was to evaluate the clinical impact of a metformin-based approach for GDM management through assessment of p...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2019.06.005
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:East African (EA) women are a subpopulation who are at very high risk for gestational diabetes (GDM) and poor obstetric outcomes, but little is known about the care experiences of this understudied group. The objective of this study was to document the impact of a diagnosis of GDM and the perceptions of diab...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2018.01.013
更新日期:2018-12-01 00:00:00
abstract::The most common presentation of chronic disease is multimorbidity. Disease management strategies are similar across most chronic diseases. Given the prevalence of multimorbidity and the commonality in approaches, fragmented single disease management must be replaced with integrated care of the whole person. The Albert...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2013.04.001
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:South Asian immigrants are generally healthy upon arrival, but precipitously develop diabetes after immigration. Whether cultural and psychosocial factors contribute to diabetes risk in this ethnic minority group remains unclear. Existing prediction models focus primarily on clinical and lifestyle factors. T...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2019.04.015
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:It was uncertain whether an algorithm that involves increasing insulin dosages by 1 unit/day may cause more hypoglycemia with the longer-acting insulin glargine 300 units/mL (GLA-300). The objective of this study was to compare safety and efficacy of 2 titration algorithms, INSIGHT and EDITION, for GLA-300 in...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jcjd.2017.06.007
更新日期:2017-10-01 00:00:00
abstract::Whether consumption of omega-3 affects circulating adiponectin has not been established. The objective of this study was to evaluate the effect of omega-3 (food or supplement) on circulating adiponectin in patients with type 2 diabetes through a systematic review of meta-analyses of randomized controlled trials. PubMe...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,meta分析
doi:10.1016/j.jcjd.2017.12.002
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:As part of a larger project to develop quality standards in perioperative diabetes management, the goal of this project was to assess self-reported management of surgical patients with diabetes across healthcare institutions and specialties in Canada. METHODS:Current practice of perioperative management of p...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2020.10.011
更新日期:2020-10-27 00:00:00
abstract:OBJECTIVES:(1) to describe pediatric patients with T1D and their caregivers' perceptions of measures of glycemic control (hemoglobin [A1C] and blood glucose [BG] levels) and (2) to determine the relationship between patients' and caregivers' perceptions of measures of glycemic control with actual A1C levels and adheren...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2017.07.002
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:1) to describe current utilization of e-mail in the clinical care of patients with diabetes; and 2) to identify barriers to and facilitators of the adoption of e-mail in diabetes care. METHODS:Participants included diabetes care providers, including 9 physicians and 7 allied health professionals (AHPs). Par...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2015.07.001
更新日期:2015-12-01 00:00:00
abstract::Routine quantification of urinary albumin levels is recommended for all Canadians with diabetes, yet many controversies remain when interpreting these tests. Elevated levels of albuminuria have traditionally been labeled as either microalbuminuria, representing 30 to 300 mg of albuminuria per day (a range not reliably...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2014.07.221
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVES:Routine food insecurity screening is recommended in diabetes care to inform more tailored interventions that better support diabetes self-management among food-insecure patients. This pilot study explored the acceptability and feasibility of a food insecurity screening initiative within a diabetes care setti...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2017.06.004
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:There are currently no recommendations on following the ketogenic diet (KD) in the context of diabetes and, therefore, health-care professionals may not be comfortable in supporting this dietary regimen. In this qualitative study, we aim to understand the perspective of patients with diabetes when following ...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章
doi:10.1016/j.jcjd.2020.06.016
更新日期:2020-06-27 00:00:00
abstract::Current management options for treating type 2 diabetes are diverse. Many different classes of antidiabetes therapies are used in clinic, and several new candidates are in late-phase clinical trial. This therapeutic abundance is a windfall for patients because it facilitates individualized patient care. Evidence-based...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2017.08.242
更新日期:2017-10-01 00:00:00
abstract::Effective glycemic control reduces the risk for diabetes-related complications. However, the majority of patients with type 2 diabetes still do not achieve glycemic targets. Beyond metformin therapy, current practice guidelines for the management of type 2 diabetes recommend individualized treatment based on patient a...
journal_title:Canadian journal of diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.jcjd.2015.09.001
更新日期:2015-12-01 00:00:00