Abstract:
AIMS:To report our experiences using Ozurdex, a biodegradable implant, containing 0.7 mg of dexamethasone in the treatment of noninfectious intermediate uveitis. SETTINGS AND DESIGN:Retrospective study design. METHODS:We conducted a retrospective study of medical records of patients with noninfectious intermediate uveitis having either cystoid macular edema (CME) or vitritis who were not responsive to standard treatment and subsequently received Ozurdex implant from March 2011 to April 2013. The outcomes measured were best-corrected visual acuity, central retinal thickness (CRT), and vitreous haze score. STATISTICAL ANALYSIS USED:Paired t-test was used to test the significance of difference between quantitative variables. A P < 0.05 is taken to denote significant relationship. RESULTS:Twenty eyes of 15 patients with mean age of 39.8 years who received Ozurdex implant were included in the study. The mean baseline visual acuity improved from 0. 666 logarithm of the minimum angle of resolution (logMAR) units to 0.479 logMAR units at 6 weeks after the implant. The mean CRT improved from 536.1 to 361.4 microns at 6 weeks postimplant both parameters were statistically significant. The ocular inflammation was controlled in almost all the patients. Cataract and raised intraocular pressure were documented complications. CONCLUSION:Ozurdex implant is a promising treatment option and efficient in controlling the inflammation and CME in cases of noninfectious intermediate uveitis not responding to standard treatment.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Palla S,Biswas J,Nagesha CKdoi
10.4103/0301-4738.171505subject
Has Abstractpub_date
2015-10-01 00:00:00pages
767-70issue
10eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2015_63_10_767_171505journal_volume
63pub_type
杂志文章abstract::Digital fundus imaging is being used in diagnosis, documentation, and sharing of many retinal diseases and hence forms an essential part of ophthalmology. The use of smartphones for the same has been ever increasing. There is a need for simpler devices to couple the 20D lens and smartphone so as to take fundus photogr...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1313_19
更新日期:2020-06-01 00:00:00
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,随机对照试验
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更新日期:2015-08-01 00:00:00
abstract::Pigmented paravenous chorioretinal atrophy (PPCRA) is an uncommon retinal disorder of unknown etiology that is neither well understood nor classified. We report an atypical case of PPCRA, associated with Coat's like response (CLR) in a 64-year-old man of Asian origin. Both the eyes were involved, though asymmetrically...
journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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doi:10.4103/0301-4738.162619
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 临床试验,杂志文章
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.136227
更新日期:2014-06-01 00:00:00
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journal_title:Indian journal of ophthalmology
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doi:10.4103/0301-4738.91337
更新日期:2012-01-01 00:00:00
abstract::A comparative retrospective study of 164 cases of juvenile secondary gla as presenting to the glaucoma service in 1984 and 100 cases in 1988, to the changes brought about by health education and innovations in ophthalmic care is undertaken. ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Indian journal of ophthalmology
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更新日期:2020-11-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.94056
更新日期:2012-03-01 00:00:00
abstract::A 78-year-old male who had received a dexamethasone implant (Ozurdex, Allergan, Inc., Irvine, CA, USA) 15 days back for recalcitrant diabetic macular edema in the left eye came to us for a second opinion. On examination, his corrected distance visual acuity was 20/20 in the right eye and 20/40 in the left eye. Early c...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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更新日期:2017-03-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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更新日期:2021-02-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.116457
更新日期:2014-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
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更新日期:2011-01-01 00:00:00