Abstract:
PURPOSE:To compare the outcome of Collagen cross-linking (CXL) with that following topography-guided customized ablation treatment (T-CAT) with simultaneous CXL in eyes with progressive keratoconus. MATERIALS AND METHODS:This was a prospective, non-randomized single centre study of 66 eyes with progressive keratoconus. Of these, 40 eyes underwent CXL and 26 eyes underwent T-CAT + CXL. The refractive, topographic, tomographic and aberrometric changes measured at baseline, 1, 3 and 6 months post-operatively were compared between both groups. RESULTS:After a mean follow-up of 7.7 ± 1.3 months, the mean retinoscopic cylinder decreased by 1.02 ± 3.16 D in the CXL group ( P = 0.1) and 2.87 ± 3.22 D in the T-CAT + CXL group ( P = 0.04). The Best corrected visual acuity increased by 2 lines or more in 10% of eyes in the CXL group and in 23.3% of eyes in the T-CAT + CXL group. The mean steepest-K reduced by 0.40 ± 3.71 D ( P = 0.77) in the CXL group and by 2.91 ± 2.01D ( P = 0.03) in the T-CAT + CXL group. The sag factor and surface asymmetry index showed no significant change in the CXL group but reduced by 3.59 ± 5.94 D ( P = 0.01) and 0.72 ± 1.18 ( P = 0.02) respectively in the T-CAT + CXL group. There was a significant increase in the highest posterior corneal elevation in both groups (9.57 ± 14.93 μ in the CXL group and 7.85 ± 9.25 μ in the T-CAT + CXL group, P ≤ 0.001 for both). There was significantly greater reduction of mean coma ( P < 0.001) and mean higher-order aberrations ( P = 0.01) following T-CAT + CXL compared to CXL. CONCLUSIONS:CAT + CXL is an effective approach to confer biomechanical stability and to improve the corneal contour in eyes with keratoconus and results in better refractive, topographic and aberrometric outcomes than CXL alone.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Padmanabhan P,Radhakrishnan A,Venkataraman AP,Gupta N,Srinivasan Bdoi
10.4103/0301-4738.111209subject
Has Abstractpub_date
2014-02-01 00:00:00pages
229-35issue
2eissn
0301-4738issn
1998-3689pii
111209journal_volume
62pub_type
临床试验,杂志文章abstract:PURPOSE:To compare Humphrey Visual Field Analyzer (HVF) and Frequency Doubling Perimetry (FDP) testing in the diagnosis of early glaucoma. METHODS:We performed HVF (24-2 standard full threshold) and FDP (N-30) evaluations in 34 consecutive patients with early primary glaucoma and 96 normal subjects. Early glaucoma was...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract:Purpose:The aim of this study was to compare the visual outcome of participants undergoing toric intraocular lens (IOL) implantation after cataract extraction using manual marking versus digital marking for intraoperative guidance. Methods:Randomized controlled trial of participants with cataract and corneal astigmati...
journal_title:Indian journal of ophthalmology
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abstract::Aripiprazole is a new drug for the treatment of adults with schizophrenia. Ocular side effects of aripiprazole are very rare. Review of literature revealed few cases of aripiprazole-induced myopia. We report a rare case of aripiprazole-induced transient myopia. A 22-year-old female patient presented to the department ...
journal_title:Indian journal of ophthalmology
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doi:10.4103/ijo.IJO_907_16
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
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abstract::This report deals with a chronological measurement of Na-K ATPase enzyme activity in human and bovine corneas stored in a moist chamber at 4 degrees C. Paired human and bovine eyes were sterilized by the standard eye bank procedure and stored up to 6 days. At the desired time, the corneal endothelium was assayed for N...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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更新日期:1996-03-01 00:00:00
abstract:AIM:To evaluate the management outcomes amongst various treatment modalities for submacular hemorrhage (SMH) in Indian subjects. SETTINGS AND DESIGN:Retrospective, single-center study. MATERIALS AND METHODS:Patients presenting with SMH between 1999 and 2006 were included. Treatment modalities included: vitrectomy wit...
journal_title:Indian journal of ophthalmology
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abstract:Purpose:Fifteen years after the publication of the Ophthalmic Clinical Evaluation Exercise (OCEX), it was deemed necessary to review and revise it, and to validate it for an international audience of ophthalmologists. This study to revise the OCEX and validate it for international use. Methods:The OCEX rubric was chan...
journal_title:Indian journal of ophthalmology
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abstract::Measles virus is a rare but important cause for acute retinitis as it can eventually lead to the fulminant complication of SSPE. We report a case of a young Indian male with acute viral retinitis who subsequently developed SSPE. It is of paramount importance to consider measles virus and SSPE as a cause in an immunoco...
journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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abstract::Visual functions of children with hearing disability were evaluated in a school of Muscat, Oman in 2006. Two hundred and twenty-three children were tested for near vision, distant vision, contrast sensitivity, color vision, field of vision, motion perception and crowding. Profound and severe hearing loss was noted in ...
journal_title:Indian journal of ophthalmology
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更新日期:2009-05-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.67042
更新日期:2010-09-01 00:00:00
abstract::Fibrous histiocytoma (FH) commonly occurs in the superficial layers of the skin. Orbit and limbus are documented ophthalmic sites of involvement but isolated corneal FH has never been reported in literature. We present the first case of FH exclusively involving the cornea where a 10-year-old male child presented with ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
pub_type:
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.103799
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:Platelets are an elective site for oxidative stress owing to their high content of polyunsaturated fatty acid. Increased lipid peroxidation and elevated platelet thiobarbituric acid-reacting substances (TBARS) signal oxidative stress. This possibly leads to retinal neovascularization in Eales' disease. METH...
journal_title:Indian journal of ophthalmology
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doi:
更新日期:2000-12-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,多中心研究
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abstract::Anterior segment infiltration in acute myeloid leukemia (AML) presenting as hypopyon uveitis is very rare. We report this case as an uncommon presentation in a patient on remission after bone marrow transplant for AML. In addition to the hypopyon, the patient presented with "red eye" caused by ocular surface disease d...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.83621
更新日期:2011-09-01 00:00:00
abstract::A 20-year-old patient, diagnosed with posterior polymorphous corneal dystrophy, developed corneal edema for which he underwent Descemet membrane endothelial keratoplasty with a stromal rim (DMEK-S) in the right eye. No intra- or postoperative complications were noted. At the last follow-up 2 years and 9 months after t...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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abstract:BACKGROUND:Many eyes with proliferative diabetic retinopathy (PDR) require vitreous surgery despite complete regression of new vessels with pan retinal laser photocoagulation (PRP). Changes in the vitreous caused by diabetes mellitus and diabetic retinopathy may continue to progress independent of laser regressed statu...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.37592
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abstract:BACKGROUND:The successful lowering of the intraocular pressure after glaucoma filtration surgery depends mostly on the nature of the healing response, which is also the single most important modifiable factor. AIMS:To evaluate and compare the effectiveness of two oxidated regenerated cellulose material, Interceed and ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.39114
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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abstract::"There are many classifications of xerophthalmia in existence. In the present study all these classification have been exhaustively reviewed. Many objections to previous classifications have been raised following experiences with these classifications for over six years. Based on these objections a self explanatory, e...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract:PURPOSE:The objective of the study was to assess the awareness and health-seeking practices related to cataract in urban slums of Delhi. METHODS:This study design was a population-based cross-sectional study. Participants aged 18-60 years were recruited from randomly selected five slums of South Delhi. They were inter...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,多中心研究
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abstract::To describe the optical coherence tomography (OCT) and electrophysiological changes in a case of closantel toxicity. A 25-year-old patient presented with sudden painless defective vision following intake of closantel. Visual acuity (VA) was counting fingers at 5 m in both eyes (BE). OCT revealed disruption of outer re...
journal_title:Indian journal of ophthalmology
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doi:10.4103/ijo.IJO_2070_18
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