Reversible blindness in a patient with closantel toxicity.

Abstract:

:To describe the optical coherence tomography (OCT) and electrophysiological changes in a case of closantel toxicity. A 25-year-old patient presented with sudden painless defective vision following intake of closantel. Visual acuity (VA) was counting fingers at 5 m in both eyes (BE). OCT revealed disruption of outer retinal layers and electroretinogram (ERG) and visual evoked potential (VEP) were subnormal in BE. The patient was treated with systemic corticosteroids, after which his VA improved to 6/9, OCT revealed preservation of central outer retinal layers, and ERG and VEP responses improved in BE. This is the first case report of successful treatment with systemic steroids for closantel-related reversible blindness.

journal_name

Indian J Ophthalmol

authors

Kumar K,Mishra C,Anjanamurthy R,Kannan NB,Ramasamy K

doi

10.4103/ijo.IJO_2070_18

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

1768-1771

issue

10

eissn

0301-4738

issn

1998-3689

pii

IndianJOphthalmol_2019_67_10_1768_267421

journal_volume

67

pub_type

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